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1 to 25 of 143  Show
  1. 1
    "Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas."
    Meyerhardt J.A., Caca K., Eckstrand B.C., Hu G., Lengauer C., Banavali S., Look A.T., Fearon E.R.
    Cell Growth Differ. 10:35-42(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], INTERACTION WITH DCC, TISSUE SPECIFICITY, VARIANTS HIS-351 AND GLU-489.
    Category: Expression, Interaction, Sequences.
    Tissue: Brain stem and Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4670 other entries.

  3. 3
    "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins."
    Li J., Liu F., Wang H., Liu X., Liu J., Li N., Wan F., Wang W., Zhang C., Jin S., Liu J., Zhu P., Liu Y.
    Mol. Cell. Proteomics 9:2517-2528(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    Category: Expression, Sequences.
    Tissue: Epididymis.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 27 other entries.

  4. 4
    "Netrin-1 controls colorectal tumorigenesis by regulating apoptosis."
    Mazelin L., Bernet A., Bonod-Bidaud C., Pays L., Arnaud S., Gespach C., Bredesen D.E., Scoazec J.-Y., Mehlen P.
    Nature 431:80-84(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 11 other entries.

  5. 5
    "DSCAM functions as a netrin receptor in commissural axon pathfinding."
    Liu G., Li W., Wang L., Kar A., Guan K.L., Rao Y., Wu J.Y.
    Proc. Natl. Acad. Sci. U.S.A. 106:2951-2956(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH DSCAM.
    Category: Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 10 other entries.

  6. 6
    "Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion."
    Shao Q., Yang T., Huang H., Alarmanazi F., Liu G.
    J. Neurosci. 37:5620-5633(2017) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 7 and mapped to 9 other entries.

  7. 7
    "A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion."
    Hong K., Hinck L., Nishiyama M., Poo M.-M., Tessier-Lavigne M., Stein E.
    Cell 97:927-941(1999) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is cited by 2 and mapped to 11 other entries.

  8. 8
    "Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate."
    Rohatgi R., Ho H.Y., Kirschner M.W.
    J. Cell Biol. 150:1299-1310(2000) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 22 other entries.

  9. 9
    "Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation."
    Stein E., Zou Y., Poo M., Tessier-Lavigne M.
    Science 291:1976-1982(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 1 other entry.

  10. 10
    "Netrin stimulates tyrosine phosphorylation of the UNC-5 family of netrin receptors and induces Shp2 binding to the RCM cytodomain."
    Tong J., Killeen M., Steven R., Binns K.L., Culotti J., Pawson T.
    J. Biol. Chem. 276:40917-40925(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is cited by 1 and mapped to 4 other entries.

  11. 11
    "The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1."
    Shekarabi M., Kennedy T.E.
    Mol. Cell. Neurosci. 19:1-17(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 12 other entries.

  12. 12
    "The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism."
    Li X., Meriane M., Triki I., Shekarabi M., Kennedy T.E., Larose L., Lamarche-Vane N.
    J. Biol. Chem. 277:37788-37797(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 7 other entries.

  13. 13
    "The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM."
    Gitai Z., Yu T.W., Lundquist E.A., Tessier-Lavigne M., Bargmann C.I.
    Neuron 37:53-65(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 11 other entries.

  14. 14
    "Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis."
    Srinivasan K., Strickland P., Valdes A., Shin G.C., Hinck L.
    Dev. Cell 4:371-382(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 7 other entries.

  15. 15
    "Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin."
    Geisbrecht B.V., Dowd K.A., Barfield R.W., Longo P.A., Leahy D.J.
    J. Biol. Chem. 278:32561-32568(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparinImported.
    Source: GeneRIF:9423.

    This publication is mapped to 5 other entries.

  16. 16
    "Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration."
    Yebra M., Montgomery A.M., Diaferia G.R., Kaido T., Silletti S., Perez B., Just M.L., Hildbrand S., Hurford R., Florkiewicz E., Tessier-Lavigne M., Cirulli V.
    Dev. Cell 5:695-707(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Interaction.
    Annotation: Data demonstrate that alpha6beta4 integrin mediates pancreatic epithelial cell adhesion to Netrin-1 whereas recruitment of alpha6beta4 and alpha3beta1 regulate the migration of putative pancreatic progenitors on Netrin-1.Imported.
    Source: GeneRIF:9423.

    This publication is mapped to 10 other entries.

  17. 17
    "Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex."
    Millard T.H., Sharp S.J., Machesky L.M.
    Biochem. J. 380:1-17(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 41 other entries.

  18. 18
    "Expression of DCC and netrin-1 in normal human endometrium and its implication in endometrial carcinogenesis."
    Kato H.D., Kondoh H., Inoue T., Asanoma K., Matsuda T., Arima T., Kato K., Yoshikawa T., Wake N.
    Gynecol. Oncol. 95:281-289(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: DCC/netrin-1 signaling may commit cells to the transition of endometrial gland architecture or function from a proliferating to a secretory phase.Imported.
    Source: GeneRIF:9423.

    This publication is mapped to 5 other entries.

  19. 19
    "Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction."
    Liu G., Beggs H., Jurgensen C., Park H.T., Tang H., Gorski J., Jones K.R., Reichardt L.F., Wu J., Rao Y.
    Nat. Neurosci. 7:1222-1232(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 4 other entries.

  20. 20
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is cited by 2 and mapped to 16 other entries.

  21. 21
    "Activation of FAK and Src are receptor-proximal events required for netrin signaling."
    Li W., Lee J., Vikis H.G., Lee S.H., Liu G., Aurandt J., Shen T.L., Fearon E.R., Guan J.L., Han M., Rao Y., Hong K., Guan K.L.
    Nat. Neurosci. 7:1213-1221(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is cited by 2 and mapped to 4 other entries.

  22. 22
    "Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance."
    Meriane M., Tcherkezian J., Webber C.A., Danek E.I., Triki I., McFarlane S., Bloch-Gallego E., Lamarche-Vane N.
    J. Cell Biol. 167:687-698(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is cited by 1 and mapped to 6 other entries.

  23. 23
    "Netrin-1 and its receptors in tumorigenesis."
    Arakawa H.
    Nat. Rev. Cancer 4:978-987(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Binding of netrin-1 to its receptors inhibits tumour suppressor p53-dependent apoptosis (review)Imported.
    Source: GeneRIF:9423.

    This publication is mapped to 14 other entries.

  24. 24
    "Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation."
    Kruger R.P., Lee J., Li W., Guan K.L.
    J. Neurosci. 24:10826-10834(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: Netrin binds through multiple domains to both DCC and Unc5c.Imported.
    Source: GeneRIF:9423.

    This publication is mapped to 13 other entries.

  25. 25
    "Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion."
    Shekarabi M., Moore S.W., Tritsch N.X., Morris S.J., Bouchard J.F., Kennedy T.E.
    J. Neurosci. 25:3132-3141(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: PathwayImported.
    Source: Reactome:R-HSA-373624.

    This publication is mapped to 11 other entries.

1 to 25 of 143  Show
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