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UniProtKB - O95625 (ZBT11_HUMAN)

Protein

Zinc finger and BTB domain-containing protein 11

Gene

ZBTB11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri569 – 591C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri597 – 619C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri651 – 673C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri679 – 701C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri707 – 729C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri735 – 757C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri766 – 788C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri794 – 816C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri822 – 846C2H2-type 9PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri858 – 880C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri886 – 908C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri914 – 937C2H2-type 12PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 11
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBTB111 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000066422.4

Human Gene Nomenclature Database

More...HGNCi		HGNC:16740 ZBTB11

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O95625

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Disease mutation, Mental retardation

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000066422

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134907354

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZBTB11

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000477271 – 1053Zinc finger and BTB domain-containing protein 11Add BLAST1053

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki1043Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1050PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O95625

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O95625

MaxQB - The MaxQuant DataBase

More...MaxQBi		O95625

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O95625

PeptideAtlas

More...PeptideAtlasi		O95625

PRoteomics IDEntifications database

More...PRIDEi		O95625

ProteomicsDB human proteome resource

More...ProteomicsDBi		50956

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O95625

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O95625

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000066422 Expressed in 232 organ(s), highest expression level in sperm

CleanEx database of gene expression profiles

More...CleanExi		HS_ZBTB11

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O95625 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O95625 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA015328
HPA024138

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		118005, 24 interactors

Protein interaction database and analysis system

More...IntActi		O95625, 8 interactors

Molecular INTeraction database

More...MINTi		O95625

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000326200

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		O95625

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O95625

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini214 – 282BTBPROSITE-ProRule annotationAdd BLAST69

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri569 – 591C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri597 – 619C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri651 – 673C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri679 – 701C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri707 – 729C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri735 – 757C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri766 – 788C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri794 – 816C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri822 – 846C2H2-type 9PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri858 – 880C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri886 – 908C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri914 – 937C2H2-type 12PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00900000141090

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000155761

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG097138

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O95625

KEGG Orthology (KO)

More...KOi		K10498

Identification of Orthologs from Complete Genome Data

More...OMAi		CNEAYID

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O95625

TreeFam database of animal gene trees

More...TreeFami		TF332263

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 6 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O95625-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSEESYRAI LRYLTNEREP YAPGTEGNVK RKIRKAAACY VVRGGTLYYQ 
        60         70         80         90        100
RRQRHRKTFA ELEVVLQPER RRDLIEAAHL GPGGTHHTRH QTWHYLSKTY 
       110        120        130        140        150
WWRGILKQVK DYIKQCSKCQ EKLDRSRPIS DVSEMLEELG LDLESGEESN 
       160        170        180        190        200
ESEDDLSNFT SSPTTASKPA KKKPVSKHEL VFVDTKGVVK RSSPKHCQAV 
       210        220        230        240        250
LKQLNEQRLS NQFCDVTLLI EGEEYKAHKS VLSANSEYFR DLFIEKGAVS 
       260        270        280        290        300
SHEAVVDLSG FCKASFLPLL EFAYTSVLSF DFCSMADVAI LARHLFMSEV 
       310        320        330        340        350
LEICESVHKL MEEKQLTVYK KGEVQTVAST QDLRVQNGGT APPVASSEGT 
       360        370        380        390        400
TTSLPTELGD CEIVLLVNGE LPEAEQNGEV GRQPEPQVSS EAESALSSVG 
       410        420        430        440        450
CIADSHPEME SVDLITKNNQ TELETSNNRE NNTVSNIHPK LSKENVISSS 
       460        470        480        490        500
PEDSGMGNDI SAEDICAEDI PKHRQKVDQP LKDQENLVAS TAKTDFGPDD 
       510        520        530        540        550
DTYRSRLRQR SVNEGAYIRL HKGMEKKLQK RKAVPKSAVQ QVAQKLVQRG 
       560        570        580        590        600
KKMKQPKRDA KENTEEASHK CGECGMVFQR RYALIMHKLK HERARDYKCP 
       610        620        630        640        650
LCKKQFQYSA SLRAHLIRHT RKDAPSSSSS NSTSNEASGT SSEKGRTKRE 
       660        670        680        690        700
FICSICGRTL PKLYSLRIHM LKHTGVKPHA CQVCGKTFIY KHGLKLHQSL 
       710        720        730        740        750
HQSQKQFQCE LCVKSFVTKR SLQEHMSIHT GESKYLCSVC GKSFHRGSGL 
       760        770        780        790        800
SKHFKKHQPK PEVRGYHCTQ CEKSFFEARD LRQHMNKHLG VKPFQCQFCD 
       810        820        830        840        850
KCYSWKKDWY SHVKSHSVTE PYRCNICGKE FYEKALFRRH VKKATHGKKG 
       860        870        880        890        900
RAKQNLERVC EKCGRKFTQL REYRRHMNNH EGVKPFECLT CGVAWADARS 
       910        920        930        940        950
LKRHVRTHTG ERPYVCPVCS EAYIDARTLR KHMTKFHRDY VPCKIMLEKD 
       960        970        980        990       1000
TLQFHNQGTQ VAHAVSILTA GMQEQESSGP QELETVVVTG ETMEALEAVA 
      1010       1020       1030       1040       1050
ATEEYPSVST LSDQSIMQVV NYVLAQQQGQ KLSEVAEAIQ TVKVEVAHIS 

GGE
Length:1,053
Mass (Da):119,384
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i156765B7334BF101
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J2L2C9J2L2_HUMAN
Zinc finger and BTB domain-containi...
ZBTB11
215Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti495D → N in AAD00172 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02189444G → S. Corresponds to variant dbSNP:rs3749323Ensembl.1
Natural variantiVAR_047465350T → N. Corresponds to variant dbSNP:rs33957144Ensembl.1
Natural variantiVAR_080760880H → Q Probable disease-associated mutation found in a consanguineous family with intellectual disability. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U69274 mRNA Translation: AAD00172.1
AK312859 mRNA Translation: BAG35711.1
CH471052 Genomic DNA Translation: EAW79786.1
BC111700 mRNA Translation: AAI11701.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS2943.1

NCBI Reference Sequences

More...RefSeqi		NP_055230.2, NM_014415.3

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.655286
Hs.743292

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000312938; ENSP00000326200; ENSG00000066422

Database of genes from NCBI RefSeq genomes

More...GeneIDi		27107

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:27107

UCSC genome browser

More...UCSCi		uc003dve.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U69274 mRNA Translation: AAD00172.1
AK312859 mRNA Translation: BAG35711.1
CH471052 Genomic DNA Translation: EAW79786.1
BC111700 mRNA Translation: AAI11701.1
CCDSiCCDS2943.1
RefSeqiNP_055230.2, NM_014415.3
UniGeneiHs.655286
Hs.743292

3D structure databases

ProteinModelPortaliO95625
SMRiO95625
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi118005, 24 interactors
IntActiO95625, 8 interactors
MINTiO95625
STRINGi9606.ENSP00000326200

PTM databases

iPTMnetiO95625
PhosphoSitePlusiO95625

Polymorphism and mutation databases

BioMutaiZBTB11

Proteomic databases

EPDiO95625
jPOSTiO95625
MaxQBiO95625
PaxDbiO95625
PeptideAtlasiO95625
PRIDEiO95625
ProteomicsDBi50956

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000312938; ENSP00000326200; ENSG00000066422
GeneIDi27107
KEGGihsa:27107
UCSCiuc003dve.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		27107
EuPathDBiHostDB:ENSG00000066422.4

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZBTB11

H-Invitational Database, human transcriptome db

More...H-InvDBi		HIX0003510
HIX0003511
HGNCiHGNC:16740 ZBTB11
HPAiHPA015328
HPA024138
neXtProtiNX_O95625
OpenTargetsiENSG00000066422
PharmGKBiPA134907354

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00900000141090
HOGENOMiHOG000155761
HOVERGENiHBG097138
InParanoidiO95625
KOiK10498
OMAiCNEAYID
OrthoDBi1318335at2759
PhylomeDBiO95625
TreeFamiTF332263

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ZBTB11

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		27107

Protein Ontology

More...PROi		PR:O95625

Gene expression databases

BgeeiENSG00000066422 Expressed in 232 organ(s), highest expression level in sperm
CleanExiHS_ZBTB11
ExpressionAtlasiO95625 baseline and differential
GenevisibleiO95625 HS

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00096 zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 12 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZBT11_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95625
Secondary accession number(s): Q2NKP9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: November 25, 2008
Last modified: January 16, 2019
This is version 153 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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