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Entry version 124 (08 May 2019)
Sequence version 1 (01 May 1999)
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Protein

Lebercilin-like protein

Gene

LCA5L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • intraciliary transport Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lebercilin-like protein
Alternative name(s):
Leber congenital amaurosis 5-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LCA5L
Synonyms:C21orf13
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:1255 LCA5L

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O95447

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000157578

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162393809

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
LCA5L

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000795071 – 670Lebercilin-like proteinAdd BLAST670

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O95447

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O95447

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O95447

PeptideAtlas

More...
PeptideAtlasi
O95447

PRoteomics IDEntifications database

More...
PRIDEi
O95447

ProteomicsDB human proteome resource

More...
ProteomicsDBi
50882

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
O95447

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O95447

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O95447

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000157578 Expressed in 102 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O95447 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O95447 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA019790
HPA032010

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127258, 8 interactors

Protein interaction database and analysis system

More...
IntActi
O95447, 19 interactors

Molecular INTeraction database

More...
MINTi
O95447

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000351008

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O95447

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili148 – 259Sequence analysisAdd BLAST112
Coiled coili305 – 336Sequence analysisAdd BLAST32
Coiled coili420 – 440Sequence analysisAdd BLAST21

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the LCA5 family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIMI Eukaryota
ENOG4111QVK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00560000077266

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000037923

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O95447

Identification of Orthologs from Complete Genome Data

More...
OMAi
RQRKHYS

Database of Orthologous Groups

More...
OrthoDBi
461316at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O95447

TreeFam database of animal gene trees

More...
TreeFami
TF323306

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026188 Lebercilin-like
IPR028933 Lebercilin_dom

The PANTHER Classification System

More...
PANTHERi
PTHR16650 PTHR16650, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15619 Lebercilin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

O95447-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLADLTKTN IDEHFFGVAL ENNRRSAACK RSPGTGDFSR NSNASNKSVD
60 70 80 90 100
YSRSQCSCGS LSSQYDYSED FLCDCSEKAI NRNYLKQPVV KEKEKKKYNV
110 120 130 140 150
SKISQSKGQK EISVEKKHTW NASLFNSQIH MIAQRRDAMA HRILSARLHK
160 170 180 190 200
IKGLKNELAD MHHKLEAILT ENQFLKQLQL RHLKAIGKYE NSQNNLPQIM
210 220 230 240 250
AKHQNEVKNL RQLLRKSQEK ERTLSRKLRE TDSQLLKTKD ILQALQKLSE
260 270 280 290 300
DKNLAEREEL THKLSIITTK MDANDKKIQS LEKQLRLNCR AFSRQLAIET
310 320 330 340 350
RKTLAAQTAT KTLQVEVKHL QQKLKEKDRE LEIKNIYSHR ILKNLHDTED
360 370 380 390 400
YPKVSSTKSV QADRKILPFT SMRHQGTQKS DVPPLTTKGK KATGNIDHKE
410 420 430 440 450
KSTEINHEIP HCVNKLPKQE DSKRKYEDLS GEEKHLEVQI LLENTGRQKD
460 470 480 490 500
KKEDQEKKNI FVKEEQELPP KIIEVIHPER ESNQEDVLVR EKFKRSMQRN
510 520 530 540 550
GVDDTLGKGT APYTKGPLRQ RRHYSFTEAT ENLHHGLPAS GGPANAGNMR
560 570 580 590 600
YSHSTGKHLS NREEMELEHS DSGYEPSFGK SSRIKVKDTT FRDKKSSLME
610 620 630 640 650
ELFGSGYVLK TDQSSPGVAK GSEEPLQSKE SHPLPPSQAS TSHAFGDSKV
660 670
TVVNSIKPSS PTEGKRKIII
Length:670
Mass (Da):76,505
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF0EE28F8F5AB70F8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
U3KPS7U3KPS7_HUMAN
Chromosome 21 open reading frame 13...
LCA5L C21orf13, hCG_401229
288Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JFB6C9JFB6_HUMAN
Lebercilin-like protein
LCA5L
189Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J198C9J198_HUMAN
Lebercilin-like protein
LCA5L
95Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J9Z3C9J9Z3_HUMAN
Lebercilin-like protein
LCA5L
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J293C9J293_HUMAN
Lebercilin-like protein
LCA5L
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JRD7C9JRD7_HUMAN
Lebercilin-like protein
LCA5L
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J5D2C9J5D2_HUMAN
Lebercilin-like protein
LCA5L
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JIJ8C9JIJ8_HUMAN
Lebercilin-like protein
LCA5L
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JYR0C9JYR0_HUMAN
Lebercilin-like protein
LCA5L
30Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RMP5A0A1D5RMP5_HUMAN
Lebercilin-like protein
LCA5L
10Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB90455 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02194717G → S. Corresponds to variant dbSNP:rs2837029Ensembl.1
Natural variantiVAR_042739547G → S1 PublicationCorresponds to variant dbSNP:rs11558767Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF121781 Genomic DNA Translation: AAD12066.1
AL163279 Genomic DNA Translation: CAB90455.1 Different initiation.
CH471079 Genomic DNA Translation: EAX09641.1
CH471079 Genomic DNA Translation: EAX09642.1
CH471079 Genomic DNA Translation: EAX09644.1
BC031059 mRNA Translation: AAH31059.1
BC043006 mRNA Translation: AAH43006.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13665.1

NCBI Reference Sequences

More...
RefSeqi
NP_689718.1, NM_152505.3
XP_005260983.1, XM_005260926.1
XP_006724030.1, XM_006723967.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000288350; ENSP00000288350; ENSG00000157578
ENST00000358268; ENSP00000351008; ENSG00000157578
ENST00000380671; ENSP00000370046; ENSG00000157578

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
150082

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:150082

UCSC genome browser

More...
UCSCi
uc002yxv.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF121781 Genomic DNA Translation: AAD12066.1
AL163279 Genomic DNA Translation: CAB90455.1 Different initiation.
CH471079 Genomic DNA Translation: EAX09641.1
CH471079 Genomic DNA Translation: EAX09642.1
CH471079 Genomic DNA Translation: EAX09644.1
BC031059 mRNA Translation: AAH31059.1
BC043006 mRNA Translation: AAH43006.1
CCDSiCCDS13665.1
RefSeqiNP_689718.1, NM_152505.3
XP_005260983.1, XM_005260926.1
XP_006724030.1, XM_006723967.1

3D structure databases

SMRiO95447
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127258, 8 interactors
IntActiO95447, 19 interactors
MINTiO95447
STRINGi9606.ENSP00000351008

PTM databases

CarbonylDBiO95447
iPTMnetiO95447
PhosphoSitePlusiO95447

Polymorphism and mutation databases

BioMutaiLCA5L

Proteomic databases

EPDiO95447
jPOSTiO95447
PaxDbiO95447
PeptideAtlasiO95447
PRIDEiO95447
ProteomicsDBi50882

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
150082
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000288350; ENSP00000288350; ENSG00000157578
ENST00000358268; ENSP00000351008; ENSG00000157578
ENST00000380671; ENSP00000370046; ENSG00000157578
GeneIDi150082
KEGGihsa:150082
UCSCiuc002yxv.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
150082

GeneCards: human genes, protein and diseases

More...
GeneCardsi
LCA5L
HGNCiHGNC:1255 LCA5L
HPAiHPA019790
HPA032010
neXtProtiNX_O95447
OpenTargetsiENSG00000157578
PharmGKBiPA162393809

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IIMI Eukaryota
ENOG4111QVK LUCA
GeneTreeiENSGT00560000077266
HOGENOMiHOG000037923
InParanoidiO95447
OMAiRQRKHYS
OrthoDBi461316at2759
PhylomeDBiO95447
TreeFamiTF323306

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
150082

Protein Ontology

More...
PROi
PR:O95447

Gene expression databases

BgeeiENSG00000157578 Expressed in 102 organ(s), highest expression level in testis
ExpressionAtlasiO95447 baseline and differential
GenevisibleiO95447 HS

Family and domain databases

InterProiView protein in InterPro
IPR026188 Lebercilin-like
IPR028933 Lebercilin_dom
PANTHERiPTHR16650 PTHR16650, 1 hit
PfamiView protein in Pfam
PF15619 Lebercilin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLCA5L_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95447
Secondary accession number(s): D3DSI0, Q3ZCT0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 8, 2019
This is version 124 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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