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Entry version 168 (31 Jul 2019)
Sequence version 2 (01 May 2000)
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Protein

Apolipoprotein M

Gene

APOM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei136Fatty acid1
Binding sitei143Fatty acid1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-975634 Retinoid metabolism and transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Apolipoprotein M
Short name:
Apo-M
Short name:
ApoM
Alternative name(s):
Protein G3a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:APOM
Synonyms:G3A, NG20
ORF Names:HSPC336
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13916 APOM

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606907 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O95445

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

HDL, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi22Q → A: Introduces a signal cleavage site. Abolishes interaction with lipoprotein particles. Leads to rapid elimination from plasma. 3 Publications1
Mutagenesisi135N → Q: Loss of glycosylation. 1 Publication1
Mutagenesisi148N → Q: No loss of glycosylation. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
55937

Open Targets

More...
OpenTargetsi
ENSG00000204444

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38370

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB08231 MYRISTIC ACID

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
APOM

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002232781 – 188Apolipoprotein MAdd BLAST188
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – ?22Not cleavedAdd BLAST22

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi23 ↔ 1671 Publication
Disulfide bondi95 ↔ 1831 Publication
Disulfide bondi128 ↔ 1571 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi135N-linked (GlcNAc...) asparagine2 Publications1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-1088
non-CPTAC-2630

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O95445

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O95445

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O95445

PeptideAtlas

More...
PeptideAtlasi
O95445

PRoteomics IDEntifications database

More...
PRIDEi
O95445

ProteomicsDB human proteome resource

More...
ProteomicsDBi
50881 [O95445-1]
63861

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1015

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O95445

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O95445

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Plasma protein. Expressed in liver and kidney.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000204444 Expressed in 159 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O95445 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O95445 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB034086
HPA051006

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
121006, 7 interactors

Protein interaction database and analysis system

More...
IntActi
O95445, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000365081

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1188
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O95445

Database of comparative protein structure models

More...
ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
O95445

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IG6S Eukaryota
ENOG4111Z0U LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001026

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000034009

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O95445

Identification of Orthologs from Complete Genome Data

More...
OMAi
WTYHLTE

Database of Orthologous Groups

More...
OrthoDBi
1302737at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O95445

TreeFam database of animal gene trees

More...
TreeFami
TF330771

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.128.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022734 ApoM
IPR012674 Calycin

The PANTHER Classification System

More...
PANTHERi
PTHR32028 PTHR32028, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11032 ApoM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50814 SSF50814, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: O95445-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFHQIWAALL YFYGIILNSI YQCPEHSQLT TLGVDGKEFP EVHLGQWYFI
60 70 80 90 100
AGAAPTKEEL ATFDPVDNIV FNMAAGSAPM QLHLRATIRM KDGLCVPRKW
110 120 130 140 150
IYHLTEGSTD LRTEGRPDMK TELFSSSCPG GIMLNETGQG YQRFLLYNRS
160 170 180
PHPPEKCVEE FKSLTSCLDS KAFLLTPRNQ EACELSNN
Length:188
Mass (Da):21,253
Last modified:May 1, 2000 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4C35FEC32B7CB86
GO
Isoform 2 (identifier: O95445-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-72: Missing.

Note: No experimental confirmation available.
Show »
Length:116
Mass (Da):13,051
Checksum:iF78244DE4A76A382
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5SRP5Q5SRP5_HUMAN
Apolipoprotein M
APOM
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1 – 38MFHQI…VDGKE → RFPDSIWGSRSDTSGSPQVP KLYFCGARRESPQPQT in AAF29014 (Ref. 3) CuratedAdd BLAST38
Sequence conflicti175 – 188LTPRN…ELSNN → VDS in CAB51604 (Ref. 2) CuratedAdd BLAST14

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0455861 – 72Missing in isoform 2. 1 PublicationAdd BLAST72

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF118393 mRNA Translation: AAD11443.2
AJ245434 mRNA Translation: CAB51604.1
AF161454 mRNA Translation: AAF29014.1
AF129756 Genomic DNA Translation: AAD18084.1
CN428415 mRNA No translation available.
BA000025 Genomic DNA Translation: BAB63389.1
AL662801 Genomic DNA No translation available.
AL670886 Genomic DNA No translation available.
AL805934 Genomic DNA No translation available.
BX511262 Genomic DNA No translation available.
CR753842 Genomic DNA No translation available.
CR354443 Genomic DNA No translation available.
CR759761 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03461.1
CH471081 Genomic DNA Translation: EAX03463.1
BC020683 mRNA Translation: AAH20683.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4710.1 [O95445-1]
CCDS59004.1 [O95445-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001243098.1, NM_001256169.1 [O95445-2]
NP_061974.2, NM_019101.2 [O95445-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000375916; ENSP00000365081; ENSG00000204444 [O95445-1]
ENST00000375920; ENSP00000365085; ENSG00000204444 [O95445-2]
ENST00000383438; ENSP00000372930; ENSG00000206409 [O95445-1]
ENST00000400157; ENSP00000383021; ENSG00000206409 [O95445-2]
ENST00000416324; ENSP00000393581; ENSG00000224290 [O95445-2]
ENST00000422771; ENSP00000392021; ENSG00000226215 [O95445-2]
ENST00000425177; ENSP00000403062; ENSG00000235754 [O95445-2]
ENST00000426800; ENSP00000405730; ENSG00000227567 [O95445-1]
ENST00000430282; ENSP00000401684; ENSG00000224290 [O95445-1]
ENST00000432598; ENSP00000389591; ENSG00000235754 [O95445-1]
ENST00000436931; ENSP00000394610; ENSG00000231974 [O95445-1]
ENST00000439902; ENSP00000413446; ENSG00000227567 [O95445-2]
ENST00000441436; ENSP00000398944; ENSG00000226215 [O95445-1]
ENST00000443975; ENSP00000416335; ENSG00000231974 [O95445-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55937

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55937

UCSC genome browser

More...
UCSCi
uc003nvk.5 human [O95445-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF118393 mRNA Translation: AAD11443.2
AJ245434 mRNA Translation: CAB51604.1
AF161454 mRNA Translation: AAF29014.1
AF129756 Genomic DNA Translation: AAD18084.1
CN428415 mRNA No translation available.
BA000025 Genomic DNA Translation: BAB63389.1
AL662801 Genomic DNA No translation available.
AL670886 Genomic DNA No translation available.
AL805934 Genomic DNA No translation available.
BX511262 Genomic DNA No translation available.
CR753842 Genomic DNA No translation available.
CR354443 Genomic DNA No translation available.
CR759761 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03461.1
CH471081 Genomic DNA Translation: EAX03463.1
BC020683 mRNA Translation: AAH20683.1
CCDSiCCDS4710.1 [O95445-1]
CCDS59004.1 [O95445-2]
RefSeqiNP_001243098.1, NM_001256169.1 [O95445-2]
NP_061974.2, NM_019101.2 [O95445-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2WEWX-ray1.95A22-188[»]
2WEXX-ray2.00A22-188[»]
2YG2X-ray1.70A/B22-188[»]
SMRiO95445
ModBaseiSearch...

Protein-protein interaction databases

BioGridi121006, 7 interactors
IntActiO95445, 2 interactors
STRINGi9606.ENSP00000365081

Chemistry databases

DrugBankiDB08231 MYRISTIC ACID

PTM databases

GlyConnecti1015
iPTMnetiO95445
PhosphoSitePlusiO95445

Polymorphism and mutation databases

BioMutaiAPOM

Proteomic databases

CPTACinon-CPTAC-1088
non-CPTAC-2630
jPOSTiO95445
MaxQBiO95445
PaxDbiO95445
PeptideAtlasiO95445
PRIDEiO95445
ProteomicsDBi50881 [O95445-1]
63861

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55937
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375916; ENSP00000365081; ENSG00000204444 [O95445-1]
ENST00000375920; ENSP00000365085; ENSG00000204444 [O95445-2]
ENST00000383438; ENSP00000372930; ENSG00000206409 [O95445-1]
ENST00000400157; ENSP00000383021; ENSG00000206409 [O95445-2]
ENST00000416324; ENSP00000393581; ENSG00000224290 [O95445-2]
ENST00000422771; ENSP00000392021; ENSG00000226215 [O95445-2]
ENST00000425177; ENSP00000403062; ENSG00000235754 [O95445-2]
ENST00000426800; ENSP00000405730; ENSG00000227567 [O95445-1]
ENST00000430282; ENSP00000401684; ENSG00000224290 [O95445-1]
ENST00000432598; ENSP00000389591; ENSG00000235754 [O95445-1]
ENST00000436931; ENSP00000394610; ENSG00000231974 [O95445-1]
ENST00000439902; ENSP00000413446; ENSG00000227567 [O95445-2]
ENST00000441436; ENSP00000398944; ENSG00000226215 [O95445-1]
ENST00000443975; ENSP00000416335; ENSG00000231974 [O95445-2]
GeneIDi55937
KEGGihsa:55937
UCSCiuc003nvk.5 human [O95445-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55937
DisGeNETi55937

GeneCards: human genes, protein and diseases

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GeneCardsi
APOM
HGNCiHGNC:13916 APOM
HPAiCAB034086
HPA051006
MIMi606907 gene
neXtProtiNX_O95445
OpenTargetsiENSG00000204444
PharmGKBiPA38370

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IG6S Eukaryota
ENOG4111Z0U LUCA
GeneTreeiENSGT00390000001026
HOGENOMiHOG000034009
InParanoidiO95445
OMAiWTYHLTE
OrthoDBi1302737at2759
PhylomeDBiO95445
TreeFamiTF330771

Enzyme and pathway databases

ReactomeiR-HSA-975634 Retinoid metabolism and transport

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
APOM human
EvolutionaryTraceiO95445

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
APOM

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55937

Protein Ontology

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PROi
PR:O95445

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000204444 Expressed in 159 organ(s), highest expression level in liver
ExpressionAtlasiO95445 baseline and differential
GenevisibleiO95445 HS

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR022734 ApoM
IPR012674 Calycin
PANTHERiPTHR32028 PTHR32028, 1 hit
PfamiView protein in Pfam
PF11032 ApoM, 1 hit
SUPFAMiSSF50814 SSF50814, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAPOM_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95445
Secondary accession number(s): B0UX98
, Q5SRP4, Q9P046, Q9UMP6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: May 1, 2000
Last modified: July 31, 2019
This is version 168 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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