Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 151 (08 May 2019)
Sequence version 2 (26 Jul 2002)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Arginyl-tRNA--protein transferase 1

Gene

ATE1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).By similarity

Caution

It is uncertain whether Met-1 or Met-37 is the initiator.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • arginyltransferase activity Source: GO_Central

GO - Biological processi

  • proteasomal protein catabolic process Source: MGI
  • protein arginylation Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processUbl conjugation pathway

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:HS03017-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.3.2.8 2681

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Arginyl-tRNA--protein transferase 1 (EC:2.3.2.8)
Short name:
Arginyltransferase 1
Short name:
R-transferase 1
Alternative name(s):
Arginine-tRNA--protein transferase 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ATE1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:782 ATE1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
607103 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O95260

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
11101

Open Targets

More...
OpenTargetsi
ENSG00000107669

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25082

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ATE1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001950881 – 518Arginyl-tRNA--protein transferase 1Add BLAST518

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei169PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O95260

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O95260

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O95260

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O95260

PeptideAtlas

More...
PeptideAtlasi
O95260

PRoteomics IDEntifications database

More...
PRIDEi
O95260

ProteomicsDB human proteome resource

More...
ProteomicsDBi
50757
50758 [O95260-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O95260

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O95260

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000107669 Expressed in 205 organ(s), highest expression level in prostate gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O95260 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O95260 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038444
HPA057549

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer. Interacts with LIAT1 (By similarity).By similarityCurated

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
SUV39H1O434632EBI-1043378,EBI-349968

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116282, 38 interactors

Protein interaction database and analysis system

More...
IntActi
O95260, 4 interactors

Molecular INTeraction database

More...
MINTi
O95260

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000224652

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O95260

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the R-transferase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1193 Eukaryota
COG2935 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00500000044926

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007968

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O95260

KEGG Orthology (KO)

More...
KOi
K00685

Database of Orthologous Groups

More...
OrthoDBi
1446907at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O95260

TreeFam database of animal gene trees

More...
TreeFami
TF105976

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR017137 Arg-tRNA-P_Trfase_1_euk
IPR030700 N-end_Aminoacyl_Trfase
IPR007472 N-end_Aminoacyl_Trfase_C
IPR007471 N-end_Aminoacyl_Trfase_N

The PANTHER Classification System

More...
PANTHERi
PTHR21367 PTHR21367, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04377 ATE_C, 1 hit
PF04376 ATE_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037207 ATE1_euk, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55729 SSF55729, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform ATE1-1 (identifier: O95260-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAFWAGGSPS VVDYFPSEDF YRCGYCKNES GSRSNGMWAH SMTVQDYQDL
60 70 80 90 100
IDRGWRRSGK YVYKPVMNQT CCPQYTIRCR PLQFQPSKSH KKVLKKMLKF
110 120 130 140 150
LAKGEVPKGS CEDEPMDSTM DDAVAGDFAL INKLDIQCDL KTLSDDIKES
160 170 180 190 200
LESEGKNSKK EEPQELLQSQ DFVGEKLGSG EPSHSVKVHT VPKPGKGADL
210 220 230 240 250
SKPPCRKAKE IRKERKRLKL MQQNPAGELE GFQAQGHPPS LFPPKAKSNQ
260 270 280 290 300
PKSLEDLIFE SLPENASHKL EVRVVRSSPP SSQFKATLLE SYQVYKRYQM
310 320 330 340 350
VIHKNPPDTP TESQFTRFLC SSPLEAETPP NGPDCGYGSF HQQYWLDGKI
360 370 380 390 400
IAVGVIDILP NCVSSVYLYY DPDYSFLSLG VYSALREIAF TRQLHEKTSQ
410 420 430 440 450
LSYYYMGFYI HSCPKMKYKG QYRPSDLLCP ETYVWVPIEQ CLPSLENSKY
460 470 480 490 500
CRFNQDPEAV DEDRSTEPDR LQVFHKRAIM PYGVYKKQQK DPSEEAAVLQ
510
YASLVGQKCS ERMLLFRN
Length:518
Mass (Da):59,090
Last modified:July 26, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBFD1CF8925CF5820
GO
Isoform ATE1-2 (identifier: O95260-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     274-314: VVRSSPPSSQ...NPPDTPTESQ → LVPVSFEDPE...DPPDECGKTE

Show »
Length:518
Mass (Da):59,032
Checksum:iD01E1D6024F04565
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GXE4F5GXE4_HUMAN
Arginyl-tRNA--protein transferase 1
ATE1
511Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B4DK25B4DK25_HUMAN
Arginyl-tRNA--protein transferase 1
ATE1
403Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B4E107B4E107_HUMAN
Arginyl-tRNA--protein transferase 1
ATE1
422Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y5C2H0Y5C2_HUMAN
Arginyl-tRNA--protein transferase 1
ATE1
515Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5SQQ1Q5SQQ1_HUMAN
Arginyl-tRNA--protein transferase 1
ATE1
222Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti5 – 11AGGSPSV → GGGFAAS in AAD12366 (PubMed:9858543).Curated7

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_000336274 – 314VVRSS…PTESQ → LVPVSFEDPEFKSSFSQSFS LYVKYQVAIHQDPPDECGKT E in isoform ATE1-2. 2 PublicationsAdd BLAST41

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC025947 Genomic DNA No translation available.
AL731542 Genomic DNA No translation available.
AL731566 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49334.1
BC022026 mRNA Translation: AAH22026.2
AF079098 mRNA Translation: AAD12366.1
AF079099 mRNA Translation: AAD12367.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31299.1 [O95260-2]
CCDS31300.1 [O95260-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001001976.1, NM_001001976.2 [O95260-1]
NP_001275663.1, NM_001288734.1
NP_001275664.1, NM_001288735.1
NP_001275665.1, NM_001288736.1
NP_008972.2, NM_007041.3 [O95260-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000224652; ENSP00000224652; ENSG00000107669 [O95260-1]
ENST00000369043; ENSP00000358039; ENSG00000107669 [O95260-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11101

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:11101

UCSC genome browser

More...
UCSCi
uc001lfp.5 human [O95260-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025947 Genomic DNA No translation available.
AL731542 Genomic DNA No translation available.
AL731566 Genomic DNA No translation available.
CH471066 Genomic DNA Translation: EAW49334.1
BC022026 mRNA Translation: AAH22026.2
AF079098 mRNA Translation: AAD12366.1
AF079099 mRNA Translation: AAD12367.1
CCDSiCCDS31299.1 [O95260-2]
CCDS31300.1 [O95260-1]
RefSeqiNP_001001976.1, NM_001001976.2 [O95260-1]
NP_001275663.1, NM_001288734.1
NP_001275664.1, NM_001288735.1
NP_001275665.1, NM_001288736.1
NP_008972.2, NM_007041.3 [O95260-2]

3D structure databases

SMRiO95260
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi116282, 38 interactors
IntActiO95260, 4 interactors
MINTiO95260
STRINGi9606.ENSP00000224652

PTM databases

iPTMnetiO95260
PhosphoSitePlusiO95260

Polymorphism and mutation databases

BioMutaiATE1

Proteomic databases

EPDiO95260
jPOSTiO95260
MaxQBiO95260
PaxDbiO95260
PeptideAtlasiO95260
PRIDEiO95260
ProteomicsDBi50757
50758 [O95260-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
11101
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000224652; ENSP00000224652; ENSG00000107669 [O95260-1]
ENST00000369043; ENSP00000358039; ENSG00000107669 [O95260-2]
GeneIDi11101
KEGGihsa:11101
UCSCiuc001lfp.5 human [O95260-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
11101
DisGeNETi11101

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ATE1
HGNCiHGNC:782 ATE1
HPAiHPA038444
HPA057549
MIMi607103 gene
neXtProtiNX_O95260
OpenTargetsiENSG00000107669
PharmGKBiPA25082

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1193 Eukaryota
COG2935 LUCA
GeneTreeiENSGT00500000044926
HOGENOMiHOG000007968
InParanoidiO95260
KOiK00685
OrthoDBi1446907at2759
PhylomeDBiO95260
TreeFamiTF105976

Enzyme and pathway databases

BioCyciMetaCyc:HS03017-MONOMER
BRENDAi2.3.2.8 2681

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ATE1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
11101

Protein Ontology

More...
PROi
PR:O95260

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000107669 Expressed in 205 organ(s), highest expression level in prostate gland
ExpressionAtlasiO95260 baseline and differential
GenevisibleiO95260 HS

Family and domain databases

InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR017137 Arg-tRNA-P_Trfase_1_euk
IPR030700 N-end_Aminoacyl_Trfase
IPR007472 N-end_Aminoacyl_Trfase_C
IPR007471 N-end_Aminoacyl_Trfase_N
PANTHERiPTHR21367 PTHR21367, 1 hit
PfamiView protein in Pfam
PF04377 ATE_C, 1 hit
PF04376 ATE_N, 1 hit
PIRSFiPIRSF037207 ATE1_euk, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATE1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95260
Secondary accession number(s): O95261, Q5SQQ3, Q8WW04
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: July 26, 2002
Last modified: May 8, 2019
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again