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Protein

Snurportin-1

Gene

SNUPN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • nuclear import signal receptor activity Source: InterPro
  • RNA cap binding Source: ProtInc

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processTransport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-191859 snRNP Assembly

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Snurportin-1
Alternative name(s):
RNA U transporter 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SNUPN
Synonyms:RNUT1, SPN1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000169371.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14245 SNUPN

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
607902 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O95149

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi27R → A: Abolishes interaction with KPNB1 and m3G-cap U1 snRNP import receptor activity. 1 Publication1
Mutagenesisi107W → A: Reduces binding to m3G-cap structure, interaction with XPO1 and snRNP import receptor activity. 2 Publications1
Mutagenesisi203 – 207FRFYW → A: Reduces binding to m3G-cap structure. 1 Publication5
Mutagenesisi276W → A: Reduces binding to m3G-cap structure, interaction with XPO1 and snRNP import receptor activity. 2 Publications1

Organism-specific databases

DisGeNET

More...
DisGeNETi
10073

Open Targets

More...
OpenTargetsi
ENSG00000169371

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34611

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL3885569

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SNUPN

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001910711 – 360Snurportin-1Add BLAST360

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei75PhosphoserineCombined sources1
Modified residuei350PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O95149

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
O95149

MaxQB - The MaxQuant DataBase

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MaxQBi
O95149

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O95149

PeptideAtlas

More...
PeptideAtlasi
O95149

PRoteomics IDEntifications database

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PRIDEi
O95149

ProteomicsDB human proteome resource

More...
ProteomicsDBi
50662

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O95149

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O95149

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000169371 Expressed in 104 organ(s), highest expression level in testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_SNUPN

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O95149 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O95149 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB005004

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259. Component of a nuclear export receptor complex composed of KPNB1, Ran, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, Ran and XPO1. Interacts (via IBB domain) with KPNB1; the interaction is direct. Interacts with DDX20, IPO7, SMN1, SNRPB and XPO1. Interacts directly with XPO1. Its interaction with XPO1 and binding to m3G-cap U snRNPs appears to be mutually exclusive.7 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei105Interaction with m3G-cap structureCombined sources1 Publication1
Sitei144Interaction with m3G-cap structureCombined sources1 Publication1
Sitei276Interaction with m3G-cap structureCombined sources1 Publication1

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115384, 31 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1032 Importin complex, Snurportin variant

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
O95149

Database of interacting proteins

More...
DIPi
DIP-48513N

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
O95149

Protein interaction database and analysis system

More...
IntActi
O95149, 20 interactors

Molecular INTeraction database

More...
MINTi
O95149

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000309831

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1360
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XK5X-ray2.40A97-300[»]
2P8QX-ray2.35B25-64[»]
2Q5DX-ray3.20C/D25-64[»]
2QNAX-ray2.84B1-66[»]
3GB8X-ray2.90B1-328[»]
3GJXX-ray2.50B/E1-360[»]
3LWWX-ray3.15B/D25-64[»]
3NBYX-ray3.42B/E15-360[»]
3NBZX-ray2.80B/E15-360[»]
3NC0X-ray2.90B/E15-360[»]
5DISX-ray2.85C1-287[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O95149

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O95149

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
O95149

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini11 – 73IBBPROSITE-ProRule annotationAdd BLAST63

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 159Necessary for interaction with XPO11 PublicationAdd BLAST159
Regioni1 – 65Necessary for interaction with KPNB1 and m3G-cap U1 and U5 snRNP import receptor activity2 PublicationsAdd BLAST65
Regioni127 – 129Interaction with m3G-cap structureCombined sources1 Publication3
Regioni208 – 328Necessary for binding to the m3G-cap structure1 PublicationAdd BLAST121

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the snurportin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3132 Eukaryota
ENOG410XQNJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000047494

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000012990

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG053257

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O95149

KEGG Orthology (KO)

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KOi
K13151

Identification of Orthologs from Complete Genome Data

More...
OMAi
YHRQTHY

Database of Orthologous Groups

More...
OrthoDBi
1342398at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O95149

TreeFam database of animal gene trees

More...
TreeFami
TF313108

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR002652 Importin-a_IBB
IPR017336 Snurportin-1
IPR024721 Snurportin-1_N

The PANTHER Classification System

More...
PANTHERi
PTHR13403 PTHR13403, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11538 Snurportin1, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037955 Snurportin-1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51214 IBB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

O95149-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELSQALAS SFSVSQDLNS TAAPHPRLSQ YKSKYSSLEQ SERRRRLLEL
60 70 80 90 100
QKSKRLDYVN HARRLAEDDW TGMESEEENK KDDEEMDIDT VKKLPKHYAN
110 120 130 140 150
QLMLSEWLID VPSDLGQEWI VVVCPVGKRA LIVASRGSTS AYTKSGYCVN
160 170 180 190 200
RFSSLLPGGN RRNSTAKDYT ILDCIYNEVN QTYYVLDVMC WRGHPFYDCQ
210 220 230 240 250
TDFRFYWMHS KLPEEEGLGE KTKLNPFKFV GLKNFPCTPE SLCDVLSMDF
260 270 280 290 300
PFEVDGLLFY HKQTHYSPGS TPLVGWLRPY MVSDVLGVAV PAGPLTTKPD
310 320 330 340 350
YAGHQLQQIM EHKKSQKEGM KEKLTHKASE NGHYELEHLS TPKLKGSSHS
360
PDHPGCLMEN
Length:360
Mass (Da):41,143
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i50B456D1C23B4BA1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BQR0H3BQR0_HUMAN
Snurportin-1
SNUPN
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTA6H3BTA6_HUMAN
Snurportin-1
SNUPN
100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BSK1H3BSK1_HUMAN
Snurportin-1
SNUPN
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BRI5H3BRI5_HUMAN
Snurportin-1
SNUPN
209Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BUB4H3BUB4_HUMAN
Snurportin-1
SNUPN
200Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF039029 mRNA Translation: AAC70906.1
CR456811 mRNA Translation: CAG33092.1
AK289475 mRNA Translation: BAF82164.1
CH471136 Genomic DNA Translation: EAW99245.1
CH471136 Genomic DNA Translation: EAW99246.1
BC004203 mRNA Translation: AAH04203.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10281.1

NCBI Reference Sequences

More...
RefSeqi
NP_001036046.1, NM_001042581.1
NP_001036053.1, NM_001042588.1
NP_005692.1, NM_005701.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.21577

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000308588; ENSP00000309831; ENSG00000169371
ENST00000564644; ENSP00000454852; ENSG00000169371
ENST00000564675; ENSP00000458053; ENSG00000169371
ENST00000567134; ENSP00000456224; ENSG00000169371

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10073

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10073

UCSC genome browser

More...
UCSCi
uc002ban.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF039029 mRNA Translation: AAC70906.1
CR456811 mRNA Translation: CAG33092.1
AK289475 mRNA Translation: BAF82164.1
CH471136 Genomic DNA Translation: EAW99245.1
CH471136 Genomic DNA Translation: EAW99246.1
BC004203 mRNA Translation: AAH04203.1
CCDSiCCDS10281.1
RefSeqiNP_001036046.1, NM_001042581.1
NP_001036053.1, NM_001042588.1
NP_005692.1, NM_005701.3
UniGeneiHs.21577

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XK5X-ray2.40A97-300[»]
2P8QX-ray2.35B25-64[»]
2Q5DX-ray3.20C/D25-64[»]
2QNAX-ray2.84B1-66[»]
3GB8X-ray2.90B1-328[»]
3GJXX-ray2.50B/E1-360[»]
3LWWX-ray3.15B/D25-64[»]
3NBYX-ray3.42B/E15-360[»]
3NBZX-ray2.80B/E15-360[»]
3NC0X-ray2.90B/E15-360[»]
5DISX-ray2.85C1-287[»]
ProteinModelPortaliO95149
SMRiO95149
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115384, 31 interactors
ComplexPortaliCPX-1032 Importin complex, Snurportin variant
CORUMiO95149
DIPiDIP-48513N
ELMiO95149
IntActiO95149, 20 interactors
MINTiO95149
STRINGi9606.ENSP00000309831

Chemistry databases

ChEMBLiCHEMBL3885569

PTM databases

iPTMnetiO95149
PhosphoSitePlusiO95149

Polymorphism and mutation databases

BioMutaiSNUPN

Proteomic databases

EPDiO95149
jPOSTiO95149
MaxQBiO95149
PaxDbiO95149
PeptideAtlasiO95149
PRIDEiO95149
ProteomicsDBi50662

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
10073
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000308588; ENSP00000309831; ENSG00000169371
ENST00000564644; ENSP00000454852; ENSG00000169371
ENST00000564675; ENSP00000458053; ENSG00000169371
ENST00000567134; ENSP00000456224; ENSG00000169371
GeneIDi10073
KEGGihsa:10073
UCSCiuc002ban.4 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
10073
DisGeNETi10073
EuPathDBiHostDB:ENSG00000169371.13

GeneCards: human genes, protein and diseases

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GeneCardsi
SNUPN
HGNCiHGNC:14245 SNUPN
HPAiCAB005004
MIMi607902 gene
neXtProtiNX_O95149
OpenTargetsiENSG00000169371
PharmGKBiPA34611

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3132 Eukaryota
ENOG410XQNJ LUCA
GeneTreeiENSGT00510000047494
HOGENOMiHOG000012990
HOVERGENiHBG053257
InParanoidiO95149
KOiK13151
OMAiYHRQTHY
OrthoDBi1342398at2759
PhylomeDBiO95149
TreeFamiTF313108

Enzyme and pathway databases

ReactomeiR-HSA-191859 snRNP Assembly

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SNUPN human
EvolutionaryTraceiO95149

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
SNUPN

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
10073

Protein Ontology

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PROi
PR:O95149

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000169371 Expressed in 104 organ(s), highest expression level in testis
CleanExiHS_SNUPN
ExpressionAtlasiO95149 baseline and differential
GenevisibleiO95149 HS

Family and domain databases

InterProiView protein in InterPro
IPR002652 Importin-a_IBB
IPR017336 Snurportin-1
IPR024721 Snurportin-1_N
PANTHERiPTHR13403 PTHR13403, 1 hit
PfamiView protein in Pfam
PF11538 Snurportin1, 1 hit
PIRSFiPIRSF037955 Snurportin-1, 1 hit
PROSITEiView protein in PROSITE
PS51214 IBB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPN1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O95149
Secondary accession number(s): A6NE34, A8K0B0, D3DW76
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: May 1, 1999
Last modified: January 16, 2019
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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