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UniProtKB - O94818 (NOL4_HUMAN)

Protein

Nucleolar protein 4

Gene

NOL4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • RNA binding Source: ProtInc
View the complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar protein 4
Alternative name(s):
Nucleolar-localized protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NOL4
Synonyms:NOLP
ORF Names:HRIHFB2255
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000101746.15

Human Gene Nomenclature Database

More...HGNCi		HGNC:7870 NOL4

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		603577 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O94818

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		8715

Open Targets

More...OpenTargetsi		ENSG00000101746

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA31674

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		NOL4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000969351 – 638Nucleolar protein 4Add BLAST638

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O94818

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O94818

MaxQB - The MaxQuant DataBase

More...MaxQBi		O94818

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O94818

PeptideAtlas

More...PeptideAtlasi		O94818

PRoteomics IDEntifications database

More...PRIDEi		O94818

ProteomicsDB human proteome resource

More...ProteomicsDBi		50459
50460 [O94818-2]
50461 [O94818-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O94818

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O94818

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed predominantly in fetal brain, adult brain and testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000101746 Expressed in 112 organ(s), highest expression level in frontal cortex

CleanEx database of gene expression profiles

More...CleanExi		HS_NOL4

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O94818 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O94818 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA046740

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		114256, 11 interactors

Protein interaction database and analysis system

More...IntActi		O94818, 14 interactors

Molecular INTeraction database

More...MINTi		O94818

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		O94818

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IEBQ Eukaryota
ENOG411245F LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159992

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000220856

The HOVERGEN Database of Homologous Vertebrate Genes

More...HOVERGENi		HBG031438

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O94818

Identification of Orthologs from Complete Genome Data

More...OMAi		NETVGHS

Database of Orthologous Groups

More...OrthoDBi		1009964at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O94818

TreeFam database of animal gene trees

More...TreeFami		TF325594

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026747 NOL4
IPR039788 NOL4/NOL4L

The PANTHER Classification System

More...PANTHERi		PTHR12449 PTHR12449, 1 hit
PTHR12449:SF17 PTHR12449:SF17, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O94818-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESERDMYRQ FQDWCLRTYG DSGKTKTVTR KKYERIVQLL NGSESSSTDN 
        60         70         80         90        100
AKFKFWVKSK GFQLGQPDEV RGGGGGAKQV LYVPVKTTDG VGVDEKLSLR 
       110        120        130        140        150
RVAVVEDFFD IIYSMHVETG PNGEQIRKHA GQKRTYKAIS ESYAFLPREA 
       160        170        180        190        200
VTRFLMSCSE CQKRMHLNPD GTDHKDNGKP PTLVTSMIDY NMPITMAYMK 
       210        220        230        240        250
HMKLQLLNSQ QDEDESSIES DEFDMSDSTR MSAVNSDLSS NLEERMQSPQ 
       260        270        280        290        300
NLHGQQDDDS AAESFNGNET LGHSSIASGG THSREMGDSN SDGKTGLEQD 
       310        320        330        340        350
EQPLNLSDSP LSAQLTSEYR IDDHNSNGKN KYKNLLISDL KMEREARENG 
       360        370        380        390        400
SKSPAHSYSS YDSGKNESVD RGAEDLSLNR GDEDEDDHED HDDSEKVNET 
       410        420        430        440        450
DGVEAERLKA FNMFVRLFVD ENLDRMVPIS KQPKEKIQAI IDSCRRQFPE 
       460        470        480        490        500
YQERARKRIR TYLKSCRRMK RSGFEMSRPI PSHLTSAVAE SILASACESE 
       510        520        530        540        550
SRNAAKRMRL ERQQDESAPA DKQCKPEATQ ATYSTSAVPG SQDVLYINGN 
       560        570        580        590        600
GTYSYHSYRG LGGGLLNLND ASSSGPTDLS MKRQLATSSG SSSSSNSRPQ 
       610        620        630 
LSPTEINAVR QLVAGYRESA AFLLRSADEL ENLILQQN
Length:638
Mass (Da):71,357
Last modified:April 5, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i02DF0130F10E0B3F
GO
Isoform 2 (identifier: O94818-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     413-514: Missing.

Show »
Length:536
Mass (Da):59,300
Checksum:i3264872F49A76C1C
GO
Isoform 3 (identifier: O94818-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-87: MESERDMYRQ...KQVLYVPVKT → MADLMQETFLHHA

Note: No experimental confirmation available.
Show »
Length:564
Mass (Da):62,970
Checksum:iF9F37733388F664D
GO
Isoform 4 (identifier: O94818-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-285: Missing.

Note: No experimental confirmation available.
Show »
Length:353
Mass (Da):39,293
Checksum:i3CF8C54C76B703FA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EPC5K7EPC5_HUMAN
Nucleolar protein 4
NOL4
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQ17K7EQ17_HUMAN
Nucleolar protein 4
NOL4
558Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ENM5K7ENM5_HUMAN
Nucleolar protein 4
NOL4
219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EID6K7EID6_HUMAN
Nucleolar protein 4
NOL4
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EIK8K7EIK8_HUMAN
Nucleolar protein 4
NOL4
24Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH00313 differs from that shown. Contaminating sequence. Sequence of unknown origin in the N-terminal part.Curated
The sequence BAA34576 differs from that shown. Reason: Frameshift at position 82.Curated
The sequence BAA34576 differs from that shown. Reason: Erroneous termination at position 38. Translated as Gln.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti637Q → H in BAH12383 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0458361 – 285Missing in isoform 4. 1 PublicationAdd BLAST285
Alternative sequenceiVSP_0433441 – 87MESER…VPVKT → MADLMQETFLHHA in isoform 3. 1 PublicationAdd BLAST87
Alternative sequenceiVSP_010080413 – 514Missing in isoform 2. 3 PublicationsAdd BLAST102

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB017800 mRNA Translation: BAA34576.1 Sequence problems.
AK296539 mRNA Translation: BAH12383.1
AK299850 mRNA Translation: BAG61712.1
AC010798 Genomic DNA No translation available.
AC018972 Genomic DNA No translation available.
AC087397 Genomic DNA No translation available.
AC104985 Genomic DNA No translation available.
BC000313 mRNA Translation: AAH00313.1 Sequence problems.
BT006763 mRNA Translation: AAP35409.1
CR456730 mRNA Translation: CAG33011.1
AB015339 mRNA Translation: BAA34797.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS11907.2 [O94818-1]
CCDS56058.1 [O94818-4]
CCDS56059.1 [O94818-3]
CCDS59308.1 [O94818-2]

Protein sequence database of the Protein Information Resource

More...PIRi		JE0335

NCBI Reference Sequences

More...RefSeqi		NP_001185475.1, NM_001198546.1
NP_001185476.1, NM_001198547.1 [O94818-3]
NP_001185477.1, NM_001198548.1 [O94818-2]
NP_001185478.1, NM_001198549.1 [O94818-4]
NP_001269456.1, NM_001282527.1
NP_003778.2, NM_003787.4 [O94818-1]
XP_006722626.1, XM_006722563.2 [O94818-1]
XP_011524539.1, XM_011526237.1 [O94818-1]
XP_011524540.1, XM_011526238.1
XP_016881548.1, XM_017026059.1 [O94818-4]

UniGene gene-oriented nucleotide sequence clusters

More...UniGenei		Hs.514795

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000261592; ENSP00000261592; ENSG00000101746 [O94818-1]
ENST00000535384; ENSP00000445733; ENSG00000101746 [O94818-4]
ENST00000538587; ENSP00000443472; ENSG00000101746 [O94818-3]
ENST00000589544; ENSP00000465450; ENSG00000101746 [O94818-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		8715

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:8715

UCSC genome browser

More...UCSCi		uc002kxt.5 human [O94818-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB017800 mRNA Translation: BAA34576.1 Sequence problems.
AK296539 mRNA Translation: BAH12383.1
AK299850 mRNA Translation: BAG61712.1
AC010798 Genomic DNA No translation available.
AC018972 Genomic DNA No translation available.
AC087397 Genomic DNA No translation available.
AC104985 Genomic DNA No translation available.
BC000313 mRNA Translation: AAH00313.1 Sequence problems.
BT006763 mRNA Translation: AAP35409.1
CR456730 mRNA Translation: CAG33011.1
AB015339 mRNA Translation: BAA34797.1
CCDSiCCDS11907.2 [O94818-1]
CCDS56058.1 [O94818-4]
CCDS56059.1 [O94818-3]
CCDS59308.1 [O94818-2]
PIRiJE0335
RefSeqiNP_001185475.1, NM_001198546.1
NP_001185476.1, NM_001198547.1 [O94818-3]
NP_001185477.1, NM_001198548.1 [O94818-2]
NP_001185478.1, NM_001198549.1 [O94818-4]
NP_001269456.1, NM_001282527.1
NP_003778.2, NM_003787.4 [O94818-1]
XP_006722626.1, XM_006722563.2 [O94818-1]
XP_011524539.1, XM_011526237.1 [O94818-1]
XP_011524540.1, XM_011526238.1
XP_016881548.1, XM_017026059.1 [O94818-4]
UniGeneiHs.514795

3D structure databases

ProteinModelPortaliO94818
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi114256, 11 interactors
IntActiO94818, 14 interactors
MINTiO94818

PTM databases

iPTMnetiO94818
PhosphoSitePlusiO94818

Polymorphism and mutation databases

BioMutaiNOL4

Proteomic databases

EPDiO94818
jPOSTiO94818
MaxQBiO94818
PaxDbiO94818
PeptideAtlasiO94818
PRIDEiO94818
ProteomicsDBi50459
50460 [O94818-2]
50461 [O94818-3]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		8715
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000261592; ENSP00000261592; ENSG00000101746 [O94818-1]
ENST00000535384; ENSP00000445733; ENSG00000101746 [O94818-4]
ENST00000538587; ENSP00000443472; ENSG00000101746 [O94818-3]
ENST00000589544; ENSP00000465450; ENSG00000101746 [O94818-2]
GeneIDi8715
KEGGihsa:8715
UCSCiuc002kxt.5 human [O94818-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8715
DisGeNETi8715
EuPathDBiHostDB:ENSG00000101746.15

GeneCards: human genes, protein and diseases

More...GeneCardsi		NOL4
HGNCiHGNC:7870 NOL4
HPAiHPA046740
MIMi603577 gene
neXtProtiNX_O94818
OpenTargetsiENSG00000101746
PharmGKBiPA31674

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IEBQ Eukaryota
ENOG411245F LUCA
GeneTreeiENSGT00940000159992
HOGENOMiHOG000220856
HOVERGENiHBG031438
InParanoidiO94818
OMAiNETVGHS
OrthoDBi1009964at2759
PhylomeDBiO94818
TreeFamiTF325594

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		NOL4 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		8715

Protein Ontology

More...PROi		PR:O94818

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000101746 Expressed in 112 organ(s), highest expression level in frontal cortex
CleanExiHS_NOL4
ExpressionAtlasiO94818 baseline and differential
GenevisibleiO94818 HS

Family and domain databases

InterProiView protein in InterPro
IPR026747 NOL4
IPR039788 NOL4/NOL4L
PANTHERiPTHR12449 PTHR12449, 1 hit
PTHR12449:SF17 PTHR12449:SF17, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOL4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O94818
Secondary accession number(s): B4DSQ0
, B7Z3Z7, F5H1E3, Q6IBS2, Q9BWF1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: April 5, 2011
Last modified: January 16, 2019
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
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