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Protein

RNA exonuclease 4

Gene

rex4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease
Biological processrRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA exonuclease 4 (EC:3.1.-.-)
Gene namesi
Name:rex4
ORF Names:SPBC1604.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1604.09c
PomBaseiSPBC1604.09c rex4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001316991 – 260RNA exonuclease 4Add BLAST260

Proteomic databases

MaxQBiO94375
PaxDbiO94375
PRIDEiO94375

PTM databases

iPTMnetiO94375

Interactioni

Protein-protein interaction databases

BioGridi276736, 3 interactors
STRINGi4896.SPBC1604.09c.1

Structurei

3D structure databases

ProteinModelPortaliO94375
SMRiO94375
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 242ExonucleaseAdd BLAST150

Sequence similaritiesi

Belongs to the REXO4 family.Curated

Phylogenomic databases

HOGENOMiHOG000182422
InParanoidiO94375
KOiK18327
OMAiMLLWREA
OrthoDBiEOG092C2R0D
PhylomeDBiO94375

Family and domain databases

CDDicd06144 REX4_like, 1 hit
Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR013520 Exonuclease_RNaseT/DNA_pol3
IPR037431 REX4_DEDDh_dom
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF00929 RNase_T, 1 hit
SMARTiView protein in SMART
SM00479 EXOIII, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit

Sequencei

Sequence statusi: Complete.

O94375-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSNWEKLK KKLDSAKSGR VEKKHSNEKK YLKSVKGKNN ENENSYIVDK
60 70 80 90 100
KRMNELKKFA KENDIPESQV LDAYGVDASK LTRKTNLETL GKYIAMDCEM
110 120 130 140 150
VGVADDMSVL ARVSIVNYHG HVVYDTYVRP KEKVTDWRTW VSGVKSFHMR
160 170 180 190 200
DAPSFEKVQA EVAKILDNRV LVGHAVHNDL KVLLLSHPRR MIRDTSRFSG
210 220 230 240 250
YRKLAKGRTP GLKKLAEVIL GRDIQSGQHS SVQDAQATME LYKKVKKEMD
260
EVAFKGLSKS
Length:260
Mass (Da):29,602
Last modified:May 1, 1999 - v1
Checksum:i1BEBBA1E8381F9F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA22342.1
PIRiT39505
RefSeqiNP_596631.1, NM_001022552.2

Genome annotation databases

EnsemblFungiiSPBC1604.09c.1; SPBC1604.09c.1:pep; SPBC1604.09c
GeneIDi2540203
KEGGispo:SPBC1604.09c

Similar proteinsi

Entry informationi

Entry nameiREXO4_SCHPO
AccessioniPrimary (citable) accession number: O94375
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: May 1, 1999
Last modified: June 20, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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