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Protein

U3 small nucleolar RNA-associated protein 15

Gene

utp15

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs) (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing, Transcription

Enzyme and pathway databases

ReactomeiR-SPO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 15
Short name:
U3 snoRNA-associated protein 15
Alternative name(s):
U3 protein 15 required for transcription
Gene namesi
Name:utp15
ORF Names:SPBC428.19c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC428.19c
PomBaseiSPBC428.19c utp15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003079221 – 494U3 small nucleolar RNA-associated protein 15Add BLAST494

Proteomic databases

MaxQBiO94365
PaxDbiO94365
PRIDEiO94365

PTM databases

iPTMnetiO94365

Interactioni

Subunit structurei

Component of the ribosomal small subunit (SSU) processome.By similarity

Protein-protein interaction databases

BioGridi277375, 1 interactor
STRINGi4896.SPBC428.19c.1

Structurei

3D structure databases

ProteinModelPortaliO94365
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati37 – 76WD 1Sequence analysisAdd BLAST40
Repeati79 – 118WD 2Sequence analysisAdd BLAST40
Repeati121 – 161WD 3Sequence analysisAdd BLAST41
Repeati164 – 202WD 4Sequence analysisAdd BLAST39
Repeati205 – 243WD 5Sequence analysisAdd BLAST39
Repeati248 – 287WD 6Sequence analysisAdd BLAST40
Repeati289 – 328WD 7Sequence analysisAdd BLAST40

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000185028
InParanoidiO94365
KOiK14549
OMAiRFKDTAY
OrthoDBiEOG092C1VIW
PhylomeDBiO94365

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR018983 U3_snoRNA-assocProt_15_C
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF09384 UTP15_C, 1 hit
PF00400 WD40, 3 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O94365-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAPAGRLQP QRFAALPNPV TAENKFWRSF KVPVVAKEYS AITSIHFSAE
60 70 80 90 100
SPYDFAVTSG ARVQIYGASS RSVKKTIARF KDTAYSGNIR KDGKLLLAGD
110 120 130 140 150
ATGLVQIFDL STRSILRALD AHQFPVHVTQ FCPYANTTFL SGSDDKTVKV
160 170 180 190 200
WDLSTGAVQY DLSGHEDYVR TASWMSATRL VSGGYDGTIR LWDTRIADPE
210 220 230 240 250
VMSFSHGEAI DVVLPMQSGS TVISAGGPSI KVWDLVAGRQ TPTKKLSNHQ
260 270 280 290 300
KSITCLAMNS ENTRLLSGGL DGHVKIYNIS DWKVVHGMKY SGPILSMGLS
310 320 330 340 350
PDSCNLVVGM SNGTLSQRTR RITKQTSSKT PFLGGVGSAF GVVGKKKQIY
360 370 380 390 400
KGENDEFYVE EARRKRLRPF DKALKSFCYS DALDMVLENG SPVLIITMLI
410 420 430 440 450
ELLHVGGLRI ALSNRDDLSL TPLINFLRKY IRDPRFSETL CIVTSTILDI
460 470 480 490
YGAALGGSVM VENAISKLRE KVEQEVAVTQ RANELVGMLQ MLSA
Length:494
Mass (Da):54,112
Last modified:May 1, 1999 - v1
Checksum:i3D3C484C12950B31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA22294.1
PIRiT40471
RefSeqiNP_595197.1, NM_001021104.2

Genome annotation databases

EnsemblFungiiSPBC428.19c.1; SPBC428.19c.1:pep; SPBC428.19c
GeneIDi2540858
KEGGispo:SPBC428.19c

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA22294.1
PIRiT40471
RefSeqiNP_595197.1, NM_001021104.2

3D structure databases

ProteinModelPortaliO94365
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277375, 1 interactor
STRINGi4896.SPBC428.19c.1

PTM databases

iPTMnetiO94365

Proteomic databases

MaxQBiO94365
PaxDbiO94365
PRIDEiO94365

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC428.19c.1; SPBC428.19c.1:pep; SPBC428.19c
GeneIDi2540858
KEGGispo:SPBC428.19c

Organism-specific databases

EuPathDBiFungiDB:SPBC428.19c
PomBaseiSPBC428.19c utp15

Phylogenomic databases

HOGENOMiHOG000185028
InParanoidiO94365
KOiK14549
OMAiRFKDTAY
OrthoDBiEOG092C1VIW
PhylomeDBiO94365

Enzyme and pathway databases

ReactomeiR-SPO-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

PROiPR:O94365

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR018983 U3_snoRNA-assocProt_15_C
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF09384 UTP15_C, 1 hit
PF00400 WD40, 3 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUTP15_SCHPO
AccessioniPrimary (citable) accession number: O94365
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: May 1, 1999
Last modified: February 28, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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Main funding by: National Institutes of Health

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