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UniProtKB - O94312 (PDP2_SCHPO)
Protein
PWWP domain-containing protein2
Gene
pdp2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- double-stranded DNA binding Source: GO_Central
- methylated histone binding Source: PomBase
- transcription coregulator activity Source: GO_Central
GO - Biological processi
- chromatin remodeling Source: PomBase
- regulation of transcription by RNA polymerase II Source: PomBase
Names & Taxonomyi
Protein namesi | Recommended name: PWWP domain-containing protein2 |
Gene namesi | Name:pdp2 ORF Names:SPBC215.07c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC215.07c, pdp2 |
VEuPathDBi | FungiDB:SPBC215.07c |
Subcellular locationi
Nucleus
- NuA3 histone acetyltransferase complex Source: PomBase
- nucleus Source: PomBase
Other locations
- chromatin Source: PomBase
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000116768 | 1 – 568 | PWWP domain-containing protein2Add BLAST | 568 |
Proteomic databases
MaxQBi | O94312 |
PaxDbi | O94312 |
PTM databases
iPTMneti | O94312 |
Interactioni
GO - Molecular functioni
- methylated histone binding Source: PomBase
Protein-protein interaction databases
BioGRIDi | 277178, 21 interactors |
STRINGi | 4896.SPBC215.07c.1 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | O94312 |
BMRBi | O94312 |
SMRi | O94312 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | O94312 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 125 – 189 | PWWPPROSITE-ProRule annotationAdd BLAST | 65 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 126 | DisorderedSequence analysisAdd BLAST | 126 | |
Regioni | 213 – 340 | DisorderedSequence analysisAdd BLAST | 128 | |
Regioni | 465 – 568 | DisorderedSequence analysisAdd BLAST | 104 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 23 | Basic and acidic residuesSequence analysisAdd BLAST | 23 | |
Compositional biasi | 24 – 49 | Polar residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 51 – 89 | Basic and acidic residuesSequence analysisAdd BLAST | 39 | |
Compositional biasi | 90 – 104 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 105 – 121 | Basic and acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 229 – 245 | Acidic residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 268 – 311 | Polar residuesSequence analysisAdd BLAST | 44 | |
Compositional biasi | 465 – 487 | Polar residuesSequence analysisAdd BLAST | 23 | |
Compositional biasi | 488 – 502 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 515 – 541 | Basic and acidic residuesSequence analysisAdd BLAST | 27 |
Phylogenomic databases
eggNOGi | ENOG502S5RN, Eukaryota |
HOGENOMi | CLU_032844_0_0_1 |
InParanoidi | O94312 |
OMAi | IVCDEEM |
PhylomeDBi | O94312 |
Family and domain databases
CDDi | cd05840, SPBC215_ISWI_like, 1 hit |
IDEALi | IID50183 |
InterProi | View protein in InterPro IPR035503, IOC4-like_PWWP IPR000313, PWWP_dom |
Pfami | View protein in Pfam PF00855, PWWP, 1 hit |
SMARTi | View protein in SMART SM00293, PWWP, 1 hit |
PROSITEi | View protein in PROSITE PS50812, PWWP, 1 hit |
i Sequence
Sequence statusi: Complete.
O94312-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTEIKDSSVK DENPGKQEES SIAVESREMS TATNNSKNIE TTSSNGAEDI
60 70 80 90 100
KIQRDVGDDK DLDDKEANDK SSKGLEEESD SKDRKTIETD QPSNNIGDIK
110 120 130 140 150
SQKSEKSNGN ARKETKQSER VNYKPGMRVL TKMSGFPWWP SMVVTESKMT
160 170 180 190 200
SVARKSKPKR AGTFYPVIFF PNKEYLWTGS DSLTPLTSEA ISQFLEKPKP
210 220 230 240 250
KTASLIKAYK MAQSTPDLDS LSVPSSESEV SEEESDQEMS EPSPIEEDYN
260 270 280 290 300
DTKARRITRK GTKKKTVTFD PSLESVPQKR LNASSNVSSN PAKKTRVSPR
310 320 330 340 350
RSTAASKKKS PSSKRASSDE IEKDKEEEEG SVANEEDVAK RTFHSREQSL
360 370 380 390 400
LFLRHKLQSS LLSPKQDLSQ VDYKLVHNYL DKLANFQGID VPLIQKTKIA
410 420 430 440 450
VVVRKIFSLA GLPKENEDEV KSICGDILEN RWKSLLQEIS SQKQLSTDAS
460 470 480 490 500
QTQDASIANE NETEIASLDE GSESKPTPSP PAEQLTDQKQ NEDNEDKVKA
510 520 530 540 550
DSNGPTQNEN ETADASKDMI SEEKSSKDAD NSLEVAGKDF AEDGTEQTPN
560
LAEPEDGVAA VDLSTGQK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA22121.1 |
PIRi | T39897 |
RefSeqi | NP_596684.1, NM_001022607.2 |
Genome annotation databases
EnsemblFungii | SPBC215.07c.1; SPBC215.07c.1:pep; SPBC215.07c |
GeneIDi | 2540653 |
KEGGi | spo:SPBC215.07c |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA22121.1 |
PIRi | T39897 |
RefSeqi | NP_596684.1, NM_001022607.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1H3Z | NMR | - | A | 118-225 | [»] | |
AlphaFoldDBi | O94312 | |||||
BMRBi | O94312 | |||||
SMRi | O94312 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 277178, 21 interactors |
STRINGi | 4896.SPBC215.07c.1 |
PTM databases
iPTMneti | O94312 |
Proteomic databases
MaxQBi | O94312 |
PaxDbi | O94312 |
Genome annotation databases
EnsemblFungii | SPBC215.07c.1; SPBC215.07c.1:pep; SPBC215.07c |
GeneIDi | 2540653 |
KEGGi | spo:SPBC215.07c |
Organism-specific databases
PomBasei | SPBC215.07c, pdp2 |
VEuPathDBi | FungiDB:SPBC215.07c |
Phylogenomic databases
eggNOGi | ENOG502S5RN, Eukaryota |
HOGENOMi | CLU_032844_0_0_1 |
InParanoidi | O94312 |
OMAi | IVCDEEM |
PhylomeDBi | O94312 |
Miscellaneous databases
EvolutionaryTracei | O94312 |
PROi | PR:O94312 |
Family and domain databases
CDDi | cd05840, SPBC215_ISWI_like, 1 hit |
IDEALi | IID50183 |
InterProi | View protein in InterPro IPR035503, IOC4-like_PWWP IPR000313, PWWP_dom |
Pfami | View protein in Pfam PF00855, PWWP, 1 hit |
SMARTi | View protein in SMART SM00293, PWWP, 1 hit |
PROSITEi | View protein in PROSITE PS50812, PWWP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PDP2_SCHPO | |
Accessioni | O94312Primary (citable) accession number: O94312 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | May 1, 1999 | |
Last modified: | May 25, 2022 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references