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UniProtKB - O94297 (OXSM_SCHPO)
Protein
Putative 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial
Gene
SPBC887.13c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
By similarityCatalytic activityi
- EC:2.3.1.41By similarityThis reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
- This reaction proceeds in the forwardBy similarity direction.
: fatty acid biosynthesis Pathwayi
This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.
GO - Molecular functioni
- 3-oxoacyl-[acyl-carrier-protein] synthase activity Source: PomBase
GO - Biological processi
- fatty acid biosynthetic process Source: PomBase
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism |
Enzyme and pathway databases
UniPathwayi | UPA00094 |
Names & Taxonomyi
Protein namesi | Recommended name: Putative 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrialCurated (EC:2.3.1.41By similarity)Alternative name(s): Beta-ketoacyl-ACP synthase mtKAS |
Gene namesi | ORF Names:SPBC887.13c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC887.13c |
VEuPathDBi | FungiDB:SPBC887.13c |
Subcellular locationi
Mitochondrion
- Mitochondrion By similarity
Mitochondrion
- mitochondrion Source: PomBase
Keywords - Cellular componenti
MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 18 | MitochondrionSequence analysisAdd BLAST | 18 | |
ChainiPRO_0000310303 | 19 – 426 | Putative 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrialAdd BLAST | 408 |
Proteomic databases
MaxQBi | O94297 |
PaxDbi | O94297 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transit peptidePhylogenomic databases
eggNOGi | KOG1394, Eukaryota |
HOGENOMi | CLU_000022_69_2_1 |
InParanoidi | O94297 |
OMAi | QIGHCLG |
PhylomeDBi | O94297 |
Family and domain databases
CDDi | cd00834, KAS_I_II, 1 hit |
Gene3Di | 3.40.47.10, 1 hit |
InterProi | View protein in InterPro IPR017568, 3-oxoacyl-ACP_synth-2 IPR000794, Beta-ketoacyl_synthase IPR014031, Ketoacyl_synth_C IPR014030, Ketoacyl_synth_N IPR020841, PKS_Beta-ketoAc_synthase_dom IPR016039, Thiolase-like |
PANTHERi | PTHR11712, PTHR11712, 1 hit |
Pfami | View protein in Pfam PF00109, ketoacyl-synt, 1 hit PF02801, Ketoacyl-synt_C, 1 hit |
PIRSFi | PIRSF000447, KAS_II, 1 hit |
SMARTi | View protein in SMART SM00825, PKS_KS, 1 hit |
SUPFAMi | SSF53901, SSF53901, 1 hit |
TIGRFAMsi | TIGR03150, fabF, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O94297-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKRVVITGLG AVTPLGNGVK TNWRNLIQGK SGIVSLKGFP EYEQIPSKVA
60 70 80 90 100
GVIPRGKEKE EWNVLDYVDQ GKLREVATFT QLALTSAAEA LKDARWIDID
110 120 130 140 150
EQEKLATGVC FGTGIGNLDD ALNENGVLNK AGIRKVSPRV ISKILINMPA
160 170 180 190 200
GYISQRYGFT ALNHTTTTAC AAGCHAIGDA FNFIKLGHAD VIIAGGSESC
210 220 230 240 250
INPLTVAGFS KARSLSTKFN DNPKAASRPF DANRDGFVIG EGSAALVLEE
260 270 280 290 300
LEHAKNRNAH IYAEIVGYGL ASDSYHITAP NPNGDAAYYA MKRSLKQAGL
310 320 330 340 350
SASQLDYINA HATSTKLGDV AESIAITRLL CDVNRNPEAF PVSSSKGSIG
360 370 380 390 400
HLLGAAGAIE SVYTVLTVQK GVLPPTLNFE YSDIPQQFQC DYVPNVAKES
410 420
RINVALSNSF GFGGTNASLC FKKFLQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA21898.1 |
PIRi | T40738 |
RefSeqi | NP_596487.1, NM_001022407.2 |
Genome annotation databases
EnsemblFungii | SPBC887.13c.1; SPBC887.13c.1:pep; SPBC887.13c |
GeneIDi | 2541226 |
KEGGi | spo:SPBC887.13c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA21898.1 |
PIRi | T40738 |
RefSeqi | NP_596487.1, NM_001022407.2 |
3D structure databases
SMRi | O94297 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4896.SPBC887.13c.1 |
Proteomic databases
MaxQBi | O94297 |
PaxDbi | O94297 |
Genome annotation databases
EnsemblFungii | SPBC887.13c.1; SPBC887.13c.1:pep; SPBC887.13c |
GeneIDi | 2541226 |
KEGGi | spo:SPBC887.13c |
Organism-specific databases
PomBasei | SPBC887.13c |
VEuPathDBi | FungiDB:SPBC887.13c |
Phylogenomic databases
eggNOGi | KOG1394, Eukaryota |
HOGENOMi | CLU_000022_69_2_1 |
InParanoidi | O94297 |
OMAi | QIGHCLG |
PhylomeDBi | O94297 |
Enzyme and pathway databases
UniPathwayi | UPA00094 |
Miscellaneous databases
PROi | PR:O94297 |
Family and domain databases
CDDi | cd00834, KAS_I_II, 1 hit |
Gene3Di | 3.40.47.10, 1 hit |
InterProi | View protein in InterPro IPR017568, 3-oxoacyl-ACP_synth-2 IPR000794, Beta-ketoacyl_synthase IPR014031, Ketoacyl_synth_C IPR014030, Ketoacyl_synth_N IPR020841, PKS_Beta-ketoAc_synthase_dom IPR016039, Thiolase-like |
PANTHERi | PTHR11712, PTHR11712, 1 hit |
Pfami | View protein in Pfam PF00109, ketoacyl-synt, 1 hit PF02801, Ketoacyl-synt_C, 1 hit |
PIRSFi | PIRSF000447, KAS_II, 1 hit |
SMARTi | View protein in SMART SM00825, PKS_KS, 1 hit |
SUPFAMi | SSF53901, SSF53901, 1 hit |
TIGRFAMsi | TIGR03150, fabF, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | OXSM_SCHPO | |
Accessioni | O94297Primary (citable) accession number: O94297 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 13, 2007 |
Last sequence update: | May 1, 1999 | |
Last modified: | September 29, 2021 | |
This is version 113 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families