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Entry version 144 (29 Sep 2021)
Sequence version 1 (01 May 1999)
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Protein

Midasin

Gene

mdn1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits. Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus.

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi159 – 166ATPSequence analysis8
Nucleotide bindingi474 – 481ATPSequence analysis8
Nucleotide bindingi901 – 908ATPSequence analysis8
Nucleotide bindingi1193 – 1200ATPSequence analysis8
Nucleotide bindingi1566 – 1573ATPSequence analysis8
Nucleotide bindingi1876 – 1883ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • ribosomal large subunit assembly Source: PomBase
  • rRNA processing Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Midasin
Alternative name(s):
Dynein-related AAA-ATPase mdn1
MIDAS-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mdn1
ORF Names:SPCC737.08
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPCC737.08, mdn1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPCC737.08

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003633861 – 4717MidasinAdd BLAST4717

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei593Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O94248

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O94248

PRoteomics IDEntifications database

More...
PRIDEi
O94248

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O94248

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Associates with pre-60S ribosomes in the nucleoplasm.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
276054, 2 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPCC737.08.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O94248

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4505 – 4707VWFAPROSITE-ProRule annotationAdd BLAST203

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni149 – 384AAA-ATPase protomer 1Sequence analysisAdd BLAST236
Regioni458 – 797AAA-ATPase protomer 2Sequence analysisAdd BLAST340
Regioni871 – 1131AAA-ATPase protomer 3Sequence analysisAdd BLAST261
Regioni1157 – 1448AAA-ATPase protomer 4Sequence analysisAdd BLAST292
Regioni1552 – 1811AAA-ATPase protomer 5Sequence analysisAdd BLAST260
Regioni1858 – 2106AAA-ATPase protomer 6Sequence analysisAdd BLAST249
Regioni2173 – 3925LinkerBy similarityAdd BLAST1753
Regioni3898 – 3924DisorderedSequence analysisAdd BLAST27
Regioni3936 – 4283DisorderedSequence analysisAdd BLAST348
Regioni4295 – 4365DisorderedSequence analysisAdd BLAST71

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3947 – 3961Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi3973 – 3992Acidic residuesSequence analysisAdd BLAST20
Compositional biasi4030 – 4046Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi4047 – 4065Acidic residuesSequence analysisAdd BLAST19
Compositional biasi4081 – 4102Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi4103 – 4192Acidic residuesSequence analysisAdd BLAST90
Compositional biasi4209 – 4228Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi4310 – 4342Basic and acidic residuesSequence analysisAdd BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the midasin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1808, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000050_0_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O94248

Identification of Orthologs from Complete Genome Data

More...
OMAi
ELGPPNI

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O94248

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.300, 4 hits
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR040848, AAA_lid_7
IPR011704, ATPase_dyneun-rel_AAA
IPR012099, Midasin
IPR041190, Midasin_AAA_lid_5
IPR027417, P-loop_NTPase
IPR002035, VWF_A
IPR036465, vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07728, AAA_5, 8 hits
PF17865, AAA_lid_5, 1 hit
PF17867, AAA_lid_7, 3 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF010340, Midasin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 6 hits
SSF53300, SSF53300, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50234, VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O94248-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVLIEWVAI YPQIYDILEH INYVPSNTLQ RLRLHQPWSK IDYDVWFLYA
60 70 80 90 100
SDEIRETCKV KYYGETKTYG EVFVLENERI SQLHRLFVSW TVSERAEHLK
110 120 130 140 150
NLLFDAGLSN LPLVELGGNV FFNSHVPLPC SLVLTKSTQE NLNRITPYLV
160 170 180 190 200
QKRPILLAGP EGIGKKFLIT QIAAKLGQQI IRIHLSDSTD PKMLIGTYTS
210 220 230 240 250
PKPGEFEWQP GVLTQAVITG KWILFTNIEH APSEVLSVLL PLLEKRQLVI
260 270 280 290 300
PSRGETIYAK GSFQMFATSS MKTKILGQRL WQILDLTYQP DECVEVVSTL
310 320 330 340 350
YPVLSIICPT LYSVYKDIFD LFSQRSFLAT SKIYRRLCLR DFYKFIKRVA
360 370 380 390 400
FLYHKFMIPS DHVVISQELQ DAVFKEAIDM FGAFIPSRDG FDLVVRNVAI
410 420 430 440 450
ELNIPPEKAL QLRYSIPVFQ NLEHNINIGR CSLKKLSTIR SCSTNSYAFT
460 470 480 490 500
SSSLGLLEQL AAGVQTNEPL LLVGETGTGK TTTIQLLAGL LGQKVTVINM
510 520 530 540 550
SQQTESSDML GGYKPINAST LGLPLHERFI DIFEQTFSSK KNAKFISMAS
560 570 580 590 600
TSARRFRWKT CLKIWKEACK LSKTVLDGQQ PLPNPQKRQK RLSNQVELRN
610 620 630 640 650
QWAKFEKEVE DFEKVLTGGS NGFMFSFVEG ALVKAVRSGH WVLLDEINLA
660 670 680 690 700
SLETLEPIGQ LLSSYESGIL LSERGDITPI TPHKNFRLFG CMNPSTDVGK
710 720 730 740 750
RELEPSFRSR FTEIYVHSPD QNLDDLLSII QKYIGSLCIG NEHVIREVAE
760 770 780 790 800
LYQVAKSLSL DGSLVDGAGQ RPHYTVRTLS RTLSYVTEIA PIYGLRRSLY
810 820 830 840 850
EGFCMSFLTL LDHTSESLLY NHVVRFTLGE LNRDQQNAIL KQIPKVPDHS
860 870 880 890 900
SYIAFCHYWL RRGSFPVEEQ EHYIITPFVQ KNLLNIARAC STRMFPILIQ
910 920 930 940 950
GPTSSGKTSM IEYVAKKTGH KFVRINNHEH TDLQEYIGTY VTDDNGSLSF
960 970 980 990 1000
REGVLVEALR NGYWIVLDEL NLAPTDVLEA LNRLLDDNRE LFIPETQVLV
1010 1020 1030 1040 1050
KPHPEFMLFA TQNPPGVYAG RKHLSRAFRN RFLEIHFDDI PENELETILH
1060 1070 1080 1090 1100
KRCKIAPSYA AKIVQVFREL SLRRQTTRIF EQKNSFATLR DLFRWAFREA
1110 1120 1130 1140 1150
VGYQQLAENG YMLLAERARD QKDKLAVQEV IEKVMKVKID TDGIYNLDSM
1160 1170 1180 1190 1200
EIFQDMSLKE GPLSKVVWTR PMIRLFCLVW RCLLAKEPVL LVGDTGCGKT
1210 1220 1230 1240 1250
TVCQILAECL HKELHIINAH QDTENGDIIG AQRPVRNRSA VNYSLHSQLC
1260 1270 1280 1290 1300
EKFNVQESLD SIDDLIEKFE KLSSSEKNDN LSNLIERQII KYRSLFEWHD
1310 1320 1330 1340 1350
GALVTAMKQG DFFLLDEISL ADDSVLERLN SVLELSRTLT LVEHSNAAVS
1360 1370 1380 1390 1400
LTAKDGFAFF ATMNPGGDYG KKELSPALRN RFTEIWVPPM VDTEDILKIV
1410 1420 1430 1440 1450
EGKLHNNKIE LARPLVEYAK WHANEYLYTD VISIRDVLSA VEFINACEIL
1460 1470 1480 1490 1500
DLNLVLFNAV SMVFIDALGS FTTFSLSNNL ASLHAERQRC FAKLNELAGS
1510 1520 1530 1540 1550
NIMASKSADI SIKFSDSSFF IGDFGIPLGD SVESDSTYSL HTDTTLMNAS
1560 1570 1580 1590 1600
KVLRALQVLK PILLEGSPGV GKTSLITALA RETGHQLVRI NLSDQTDLMD
1610 1620 1630 1640 1650
LFGSDVPVEG GEGGQFAWRD APFLAAMRNG HWVLLDELNL ASQSVLEGLN
1660 1670 1680 1690 1700
ACLDHRNEAY IPELDKVFKA HPNFRVFAAQ NPQHQGGGRK GLPRSFINRF
1710 1720 1730 1740 1750
SVVYVEALKE KDMIEIAACN YHQVNEDWRL KIIKFMFRLQ DNIEKDISFG
1760 1770 1780 1790 1800
SFGSPWEFNL RDTLRWLQLL NDAPKYTCVS PADYLEVMVL HRMRTVEDRV
1810 1820 1830 1840 1850
RTCELFKEVF DIDYEPRTIG FSLSSQCFKV GHSLLVRDVE RQKTLLDSQN
1860 1870 1880 1890 1900
ILQSQLPVLE SVITCINKKW PCILVGDTAT GKTCILRLLA AIAGAKIKEM
1910 1920 1930 1940 1950
AVNSDTDTMD LIGEYEQIDI SRKASELFTD LSQQLLNIVI KYRNFDNIFR
1960 1970 1980 1990 2000
ETSLYTLTTT SFKTHSQAFT LLQKVVDQLD QLKIHETLVH SLGDIHEKAR
2010 2020 2030 2040 2050
KLLAEFSASP AGRFEWFDGY LLKAVEEGHW FVLDNANLCS PAVLDRLNSL
2060 2070 2080 2090 2100
LEHKGVLIVN EKTTEDGHPK TIKPHPNFRL FLTVNPVYGE LSRAMRNRGV
2110 2120 2130 2140 2150
EIFLLKEALT EIDKKQMSLL EPAPISSAVD TLASNISYIK YVFETMGKIE
2160 2170 2180 2190 2200
IDGNYMYIAH AIILALFSPR QLKLLRKVLL TNPQFSLSIK ADAELLLTLK
2210 2220 2230 2240 2250
NLVQKIYCAD YFNHMDLKAS RFMDIYEYPV QLREVVGLIQ TINDFQSVIL
2260 2270 2280 2290 2300
TSHLELPETY ASGLLFVSAH EILDLTEEVN RLAVSTSNST YLLKSASAVY
2310 2320 2330 2340 2350
HNVSSFKGST PSLWNLLNQF SKFLIEIASA NSNIVYKLSY DVIRHFLKLV
2360 2370 2380 2390 2400
VLWKNIYVWT NVPDCDISRF YCYTKMLGEW MFTLTEKTKL LESFLPKDSL
2410 2420 2430 2440 2450
EKFSELQNLS TGLHMQAIWD KWHAFVPRTY DQWSLWNTVD KLLTQYVNAN
2460 2470 2480 2490 2500
IPSISMETTA CEVVGTSLSL LNKVLVENEV GDIYSYLKIL GKGVNELKSS
2510 2520 2530 2540 2550
KQVILPENLV NLFNCLASLD LLHIFIKYTT SSFFLTDDFV RFIRVCFHSR
2560 2570 2580 2590 2600
ISGNLLTLLH GISFDSTKAV APVLTYFDFC SLTTGNILGR IALAFTSIDE
2610 2620 2630 2640 2650
NANLESANIF EHARLALLQH FMDHSSLLAE DSSTKMNLIL LQRYAVIISI
2660 2670 2680 2690 2700
FLDQGKCEKA NDLITKLSLP YEELAENFVS ILEACKAFLV ANSEFISYTY
2710 2720 2730 2740 2750
TERFIHSLRF LKDSWLSSNQ QKMLKNQGMA YIYFASGMLL VYVPDKPFDP
2760 2770 2780 2790 2800
ALLPLLTVES LRHYLESLYK ESQILEIAES LNSGKVNSVM RRLVSTEISN
2810 2820 2830 2840 2850
TPNIDSSFST VYRSLNESIV PLYSELEFFM KSVVLNQYIF ELAMRLSKES
2860 2870 2880 2890 2900
NIAVVEEAKS FVTKWKAYIE RIREAYPQFV DVYELILSFI SFMIYGIELL
2910 2920 2930 2940 2950
MFEAKRRLDE RSQILSTLIL TLVDPSSFAR SLSFDDVSNL IEQIKVLDLN
2960 2970 2980 2990 3000
DSIRFEIYLF LASRLCSEKQ HSSDTHSLAN SFVLLANEFY IHNAKIKQKE
3010 3020 3030 3040 3050
LEEIEEKNRL YRQREFNFDK NDYLKVFINY DDEVEPEVEP EVVIERKRFL
3060 3070 3080 3090 3100
QLQFAFWSLY NEIYSEKMNV IPLEQLMNTG SYLAKKIKVK NPDMIASSGF
3110 3120 3130 3140 3150
DIVSVVLMMG VKSTNERQYW TPPVYNFYSD PNPSKAIEVR DLIKIVESRA
3160 3170 3180 3190 3200
ISLIKNWPEN FVLRGLKDAI DAILNLSPFS PIAEYLSKLE RVFHLLSEWE
3210 3220 3230 3240 3250
KLASREYSLA NEMDLIKKKI IDWRKFELSN WNNLLKLEEY KLSERVYPRL
3260 3270 3280 3290 3300
YSILQFIILK PFFENSKFTK QNLCESASII VQFITDLTVG EFQLCLKCLL
3310 3320 3330 3340 3350
SFSQHAASLR ICHGIDAMLL NIYHYFEQFL SKVSEAIHTQ KQSLENSIKE
3360 3370 3380 3390 3400
RILLMSWKDT NVYALKESAK KSHAELFKVL HRYREVLRQP VSSYLSQKHD
3410 3420 3430 3440 3450
WDSLLDTENN SAMWVAKKVN LSPSYIEKMD TEIMKLVPVR FSNTPTTLRL
3460 3470 3480 3490 3500
MWTLFANVEK PGSTFTNMVS NLITDARELM KLTPETINDD NLSEIKHLKS
3510 3520 3530 3540 3550
RKHLLLTETF KTLKAFGLQY RVKAGIEENL SNLRNLLAVI PTFPVTSLSI
3560 3570 3580 3590 3600
EKVDRSLMKS LDFIPKFQTL AGHQHNDLSV PEVQKGVGLF NSMLSLQLGE
3610 3620 3630 3640 3650
RAQLVEFTNE LLALKNVYSE VGVNGSPLES FNNSSFNEVS SLGYDHDFEN
3660 3670 3680 3690 3700
RAQAVSMLCQ IYAIVIQKHS SISPTASFQS IGHELSRFAD LLSNKLFPSS
3710 3720 3730 3740 3750
IPLYASADKV SSIRDQQKGI NDLIEYCRKK RTELPELSYC FKHLVSLQSL
3760 3770 3780 3790 3800
KSISRTQVDL TNDEFLNLMN FVLNLFDSLL SSIETATKNM RTFKELAETS
3810 3820 3830 3840 3850
SFIEMSSCFS KVLRAFNLKF QSMKLSSLKE KLRSSSVDKM SCQLLMLFLP
3860 3870 3880 3890 3900
VCEQFINLAE SVLDYFINVH NSNLDSLSKI STLFFMVANN GFCSPDLPQE
3910 3920 3930 3940 3950
GKSNSGELES GTGLGSGVGA EDITNTLNED DDLEELANEE DTANQSDLDE
3960 3970 3980 3990 4000
SEARELESDM NGVTKDSVVS ENENSDSEEE NQDLDEEVND IPEDLSNSLN
4010 4020 4030 4040 4050
EKLWDEPNEE DLLETEQKSN EQSAANNESD LVSKEDDNKA LEDKDRQEKE
4060 4070 4080 4090 4100
DEEEMSDDVG IDDEIQPDIQ ENNSQPPPEN EDHLDLPEDL KLDEKEGDVS
4110 4120 4130 4140 4150
KDSDLEDMDM EAADENKEEA DAEKDEPMQD FEDPLEENNT LDEDIQQDDF
4160 4170 4180 4190 4200
SDLAEDDEKM NEDGFEENVQ ENEESTEDGV KSDEELEQGE VPEDQAIDNH
4210 4220 4230 4240 4250
PKMDAKSTFA SAEADEENTD KGIVGENEEL GEEDGAAESG VRGNGTADGE
4260 4270 4280 4290 4300
FSSAEQVQKG EDTSTPKEAM SEADRQYQSL GDHLREWQQA NRIHEWEDLT
4310 4320 4330 4340 4350
ESQSQAFDDS EFMHVKEDEE EDLQALGNAE KDQIKSIDRD ESANQNPDSM
4360 4370 4380 4390 4400
NSTNIAEDEA DEVGDKQLQD GQDISDIKQT GEDTLPTEFG SINQSEKVFE
4410 4420 4430 4440 4450
LSEDEDIEDE LPDYNVKITN LPAAMPIDEA RDLWNKHEDS TKQLSIELCE
4460 4470 4480 4490 4500
QLRLILEPTL ATKMQGDFRT GKRLNMKRII PYIASQFKKD KIWMRRVKPS
4510 4520 4530 4540 4550
KRTYQVMISI DDSKSMSESG STVLALETLA LVTKALSLLE VGQIAVMKFG
4560 4570 4580 4590 4600
EQPELLHPFD KQFSSESGVQ MFSHFTFEQS NTNVLALADA SMKCFNYANT
4610 4620 4630 4640 4650
ASHHRSNSDI RQLEIIISDG ICEDHDSIRK LLRRAQEEKV MIVFVILDNV
4660 4670 4680 4690 4700
NTQKKSSILD IKKVYYDTKE DGTMDLKIQP YIDEFAFDYY LVVRNIEELP
4710
QLLSSALRQW FQQMSNT
Length:4,717
Mass (Da):537,787
Last modified:May 1, 1999 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB2B08A69419EF502
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20864.1

Protein sequence database of the Protein Information Resource

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PIRi
T41581

NCBI Reference Sequences

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RefSeqi
NP_588370.1, NM_001023361.2

Genome annotation databases

Ensembl fungal genome annotation project

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EnsemblFungii
SPCC737.08.1; SPCC737.08.1:pep; SPCC737.08

Database of genes from NCBI RefSeq genomes

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GeneIDi
2539491

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
spo:SPCC737.08

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20864.1
PIRiT41581
RefSeqiNP_588370.1, NM_001023361.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6OR5electron microscopy4.00A1-4717[»]
6OR6electron microscopy5.30A1-4717[»]
6ORBelectron microscopy7.70A1-4717[»]
SMRiO94248
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi276054, 2 interactors
STRINGi4896.SPCC737.08.1

PTM databases

iPTMnetiO94248

Proteomic databases

MaxQBiO94248
PaxDbiO94248
PRIDEiO94248

Genome annotation databases

EnsemblFungiiSPCC737.08.1; SPCC737.08.1:pep; SPCC737.08
GeneIDi2539491
KEGGispo:SPCC737.08

Organism-specific databases

PomBaseiSPCC737.08, mdn1
VEuPathDBiFungiDB:SPCC737.08

Phylogenomic databases

eggNOGiKOG1808, Eukaryota
HOGENOMiCLU_000050_0_2_1
InParanoidiO94248
OMAiELGPPNI
PhylomeDBiO94248

Miscellaneous databases

Protein Ontology

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PROi
PR:O94248

Family and domain databases

Gene3Di3.40.50.300, 4 hits
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR040848, AAA_lid_7
IPR011704, ATPase_dyneun-rel_AAA
IPR012099, Midasin
IPR041190, Midasin_AAA_lid_5
IPR027417, P-loop_NTPase
IPR002035, VWF_A
IPR036465, vWFA_dom_sf
PfamiView protein in Pfam
PF07728, AAA_5, 8 hits
PF17865, AAA_lid_5, 1 hit
PF17867, AAA_lid_7, 3 hits
PIRSFiPIRSF010340, Midasin, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 5 hits
SUPFAMiSSF52540, SSF52540, 6 hits
SSF53300, SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50234, VWFA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMDN1_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O94248
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 1, 1999
Last modified: September 29, 2021
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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