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Protein
Submitted name:

Androgen receptor alpha

Gene

AR-alpha

Organism
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi495 – 570Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Androgen receptor alphaImported
Gene namesi
Name:AR-alphaImported
OrganismiOncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)Imported
Taxonomic identifieri8022 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeOncorhynchus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO93244
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini495 – 570Nuclear receptorInterPro annotationAdd BLAST76
Domaini599 – 833NR LBDInterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG007583

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

O93244-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEIPVGLGGV CDSTNLVFRG PFQNVFHNVQ ALPSNTTVTE SLDFCSSKFS
60 70 80 90 100
FLQNKQPWEM RQASRQSSRK EIWSGTARNS DIEVREDDSV GFSRTLESVA
110 120 130 140 150
CRIHFAKSSK GNKAGFSSLN ESDNPNANEY GSCRSGQQVS NTEQQSCQPS
160 170 180 190 200
VSHHGNELNH NSEACVASSC SSSACSTISK TARELCNAVS VSLGLTMDAN
210 220 230 240 250
EMTDLGPNHA PSSVNHQSQG NYLFEVPLLK CSGAGENVSI TEYTCPSERN
260 270 280 290 300
AKPLQSDKQL VEMFQRSPAN DLTEKVATIQ HLSSGHPCTD KQEFRLNENR
310 320 330 340 350
DDPTSKETDH FLNTGARSRS YHFDQLLPAH LAHFSQTETD RNSSHVFYKP
360 370 380 390 400
PAHVGETGET MEDKYADYLQ QQYSVKIKYE AFNRHNELPE PSWDFQYRYN
410 420 430 440 450
DNDNTQYGLN SYIAGPDSAL ICNPHEYERG GGLVRRERPT PEQWYPGEML
460 470 480 490 500
GRMPYPNSPC IKNEVGDSLD VSYTDARFEG GSDHMYPMEF FFPPQRTCLI
510 520 530 540 550
CAEEASGCHY GALTCGSCKV FFKRAAEGKQ KYLCASRNDC TIDKLRRKNC
560 570 580 590 600
PSCRLRRCFE AGMTLGTRKL KKIVQLKSPE EDLPTQGPTD TIQGVSPQSG
610 620 630 640 650
LSFHSQLVFL NILESIEPEV VHAGHDQCQP DSAAALLTSL NELGERQLVK
660 670 680 690 700
VVKWAKGLPG FRNLHVDDQM TVIQHSWMGV MVFGLGWRSY KNANCRLLYF
710 720 730 740 750
APDLVFNDHR MHISSMFDHC IRMRQLSQEF VLLQVTQEEF LCMKALLLFS
760 770 780 790 800
IIPVDGLKSQ KYFDELRLTY INELGRVINY GRKSNCSQRL YQLTRLMDSL
810 820 830 840 850
QPVVRKLQQF TFDLFVQAQS LPTKVNFPEM IAEIISVHLP KILAGLAKPI

LFHK
Length:854
Mass (Da):96,237
Last modified:November 1, 1998 - v1
Checksum:i9F123B27874B0728
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012095 mRNA Translation: BAA32784.1
RefSeqiNP_001117656.1, NM_001124184.1
UniGeneiOmy.30065

Genome annotation databases

GeneIDi100135788

Similar proteinsi

Entry informationi

Entry nameiO93244_ONCMY
AccessioniPrimary (citable) accession number: O93244
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 12, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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