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Entry version 160 (16 Oct 2019)
Sequence version 2 (27 Jul 2011)
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Protein

Carboxypeptidase D

Gene

Cpd

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Releases C-terminal Arg and Lys from polypeptides. EC:3.4.17.22

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 2 Zn2+ ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi138Zinc 1; catalyticBy similarity1
Metal bindingi141Zinc 1; catalyticBy similarity1
Metal bindingi256Zinc 1; catalyticBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei349Important for catalytic activityBy similarity1
Metal bindingi563Zinc 2; catalyticBy similarity1
Metal bindingi566Zinc 2; catalyticBy similarity1
Metal bindingi670Zinc 2; catalyticBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei761Proton donor/acceptorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCarboxypeptidase, Hydrolase, Metalloprotease, Protease
LigandMetal-binding, Zinc

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.4.17.22 3474

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-432722 Golgi Associated Vesicle Biogenesis

Protein family/group databases

MEROPS protease database

More...
MEROPSi
M14.011

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Carboxypeptidase D (EC:3.4.17.22)
Alternative name(s):
Metallocarboxypeptidase D
gp180
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cpd
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:107265 Cpd

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini38 – 1296ExtracellularSequence analysisAdd BLAST1259
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1297 – 1317HelicalSequence analysisAdd BLAST21
Topological domaini1318 – 1377CytoplasmicSequence analysisAdd BLAST60

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 37Sequence analysisAdd BLAST37
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000440238 – 1377Carboxypeptidase DAdd BLAST1340

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi171N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi216N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei264PhosphotyrosineCombined sources1
Modified residuei269PhosphoserineCombined sources1
Glycosylationi398N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi409N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi428N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi521N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi625N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi810N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi854N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi866N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi878N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi952N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi975N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1067N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1139N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi1314S-palmitoyl cysteineBy similarity1
Lipidationi1318S-palmitoyl cysteineBy similarity1
Lipidationi1320S-palmitoyl cysteineBy similarity1
Modified residuei1355PhosphoserineCombined sources1
Modified residuei1358PhosphoserineCombined sources1
Modified residuei1365PhosphothreonineCombined sources1
Modified residuei1367PhosphothreonineCombined sources1

Keywords - PTMi

Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O89001

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O89001

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O89001

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O89001

PeptideAtlas

More...
PeptideAtlasi
O89001

PRoteomics IDEntifications database

More...
PRIDEi
O89001

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2184

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O89001

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O89001

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O89001

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000020841 Expressed in 311 organ(s), highest expression level in submandibular gland

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O89001 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
O89001, 3 interactors

Molecular INTeraction database

More...
MINTi
O89001

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000021201

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O89001

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni38 – 492Carboxypeptidase-like 1Add BLAST455
Regioni493 – 896Carboxypeptidase-like 2Add BLAST404
Regioni897 – 1296Carboxypeptidase-like 3Add BLAST400

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi161 – 163Cell attachment siteSequence analysis3

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

There are 3 carboxypeptidase-like domains. Only the first two domains seem to have kept a catalytic activity.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase M14 family.Curated

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2649 Eukaryota
ENOG410XX0H LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156919

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000046445

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O89001

KEGG Orthology (KO)

More...
KOi
K07752

Identification of Orthologs from Complete Genome Data

More...
OMAi
GCPNKSD

Database of Orthologous Groups

More...
OrthoDBi
101221at2759

TreeFam database of animal gene trees

More...
TreeFami
TF315592

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03863 M14_CPD_II, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008969 CarboxyPept-like_regulatory
IPR034224 M14_CPD_II
IPR015567 Pept_M14B_carboxypept_D2
IPR000834 Peptidase_M14

The PANTHER Classification System

More...
PANTHERi
PTHR11532:SF73 PTHR11532:SF73, 3 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00246 Peptidase_M14, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00765 CRBOXYPTASEA

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00631 Zn_pept, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49464 SSF49464, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00132 CARBOXYPEPT_ZN_1, 2 hits
PS00133 CARBOXYPEPT_ZN_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

O89001-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASGRDERPP WRLGRLRLLP PPPLLLLLLL LRSSAQAAHI KKAEATTTTV
60 70 80 90 100
GGSEAAEGQF DHYYHEAALG EALEAAAAAG PPGLARLFSI GSSVEGRPLW
110 120 130 140 150
VLRLTAGLGP PPTAAAGLDA AGPLLPGRPQ VKLVGNMHGD ETVSRQVLVY
160 170 180 190 200
LARELASGYR RGDPRLVRLL NTTDVYLLPS LNPDGFERAR EGDCGLGDSG
210 220 230 240 250
PPGTSGRDNS RGRDLNRSFP DQFSTGEPPS LDEVPEVRAL IDWIRRNKFV
260 270 280 290 300
LSGNLHGGSV VASYPFDDSP EHKTTGLYSK TSDDEVFRYL AKAYASNHPI
310 320 330 340 350
MKTGEPHCPG DEDETFKDGI TNGAHWYDVE GGMQDYNYVW ANCFEITLEL
360 370 380 390 400
SCCKYPPASQ LRQEWENNRE SLITLIEKVH IGIKGFVKDS VTGSGLENAT
410 420 430 440 450
ISVAGINHNI TTGRFGDFHR LLVPGTYNLT ALSTGYMPLT INNIMVKEGP
460 470 480 490 500
ATEMDFSLRP TVMSVMPGST EAVTTPGTVA VPNIPPGTPS SHQPIQPKDF
510 520 530 540 550
HHHHFPDMEI FLRRFANEYP NITRLYSLGK SVESRELYVM EISDNPGVHE
560 570 580 590 600
PGEPEFKYIG NMHGNEVVGR ELLLNLIEYL CKNFGTDPEV TDLVRSTRIH
610 620 630 640 650
LMPSMNPDGY EKSQEGDSIS VVGRNNSNNF DLNRNFPDQF VPITEPTQPE
660 670 680 690 700
TIAVMSWVKA YPFVLSANLH GGSLVVNYPY DDNEQGVATY SKSPDDAVFQ
710 720 730 740 750
QIALSYSKEN SQMFQGRPCK DMYLNEYFPH GITNGASWYN VPGGMQDWNY
760 770 780 790 800
LQTNCFEVTI ELGCVKYPFE NELPKYWEQN RRSLIQFMKQ VHQGVKGFVL
810 820 830 840 850
DATDGRGILN ATLSVAEINH PVTTYKAGDY WRLLVPGTYK ITASARGYNP
860 870 880 890 900
VTKNVTVRSE GAVQVNFTLV RSSADANNES KKGRGHSTST DDTSDPTSKE
910 920 930 940 950
FEALIKHLSA ENGLEGFMLS SSSDLALYRY HSYKDLSEFL RGLVMNYPHI
960 970 980 990 1000
TNLTTLGQSV EYRHIWSLEI SNKPNISEPE EPKIRFVAGI HGNAPVGTEL
1010 1020 1030 1040 1050
LLALAEFLCL NYKRNPVVTQ LVDRTRIVIV PSLNPDGRER AQEKDCTSKT
1060 1070 1080 1090 1100
GHTNAHGKDL DTDFTSNASQ PETKAIIENL IQKQDFSLSI ALDGGSVLVT
1110 1120 1130 1140 1150
YPYDKPVQTV ENKETLKHLA SLYANNHPSM HMGQPSCPNN SDENIPGGVM
1160 1170 1180 1190 1200
RGAEWHSHLG SMKDYSVTYG HCPEITVYTS CCYFPSAAQL PALWAENKKS
1210 1220 1230 1240 1250
LLSMLVEVHK GVHGLVKDKA GKPISKAVIV LNEGIKVYTK EGGYFHVLLA
1260 1270 1280 1290 1300
PGVHNINAIA DGYQQQHTQV FVHHDAASSV VIVFDTDNRI FGLPRELVVT
1310 1320 1330 1340 1350
VSGATMSALI LTACIIWCIC SIKSNRHKDG FHRLRQHHDE YEDEIRMMST
1360 1370
GSKKSLLSHE FQDETDTEEE TLYSSKH
Length:1,377
Mass (Da):152,406
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73CC0861EE674053
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti53S → T in BAA33371 (PubMed:9714835).Curated1
Sequence conflicti1039 – 1040ER → DG in BAA33371 (PubMed:9714835).Curated2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
D85391 mRNA Translation: BAA33371.1
AK137737 mRNA Translation: BAE23483.1
AL645479 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25071.1

NCBI Reference Sequences

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RefSeqi
NP_031780.2, NM_007754.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000021201; ENSMUSP00000021201; ENSMUSG00000020841

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
12874

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:12874

UCSC genome browser

More...
UCSCi
uc007kga.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D85391 mRNA Translation: BAA33371.1
AK137737 mRNA Translation: BAE23483.1
AL645479 Genomic DNA No translation available.
CCDSiCCDS25071.1
RefSeqiNP_031780.2, NM_007754.2

3D structure databases

SMRiO89001
ModBaseiSearch...

Protein-protein interaction databases

IntActiO89001, 3 interactors
MINTiO89001
STRINGi10090.ENSMUSP00000021201

Protein family/group databases

MEROPSiM14.011

PTM databases

GlyConnecti2184
iPTMnetiO89001
PhosphoSitePlusiO89001
SwissPalmiO89001

Proteomic databases

EPDiO89001
jPOSTiO89001
MaxQBiO89001
PaxDbiO89001
PeptideAtlasiO89001
PRIDEiO89001

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
12874

Genome annotation databases

EnsembliENSMUST00000021201; ENSMUSP00000021201; ENSMUSG00000020841
GeneIDi12874
KEGGimmu:12874
UCSCiuc007kga.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1362
MGIiMGI:107265 Cpd

Phylogenomic databases

eggNOGiKOG2649 Eukaryota
ENOG410XX0H LUCA
GeneTreeiENSGT00940000156919
HOGENOMiHOG000046445
InParanoidiO89001
KOiK07752
OMAiGCPNKSD
OrthoDBi101221at2759
TreeFamiTF315592

Enzyme and pathway databases

BRENDAi3.4.17.22 3474
ReactomeiR-MMU-432722 Golgi Associated Vesicle Biogenesis

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Cpd mouse

Protein Ontology

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PROi
PR:O89001

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000020841 Expressed in 311 organ(s), highest expression level in submandibular gland
GenevisibleiO89001 MM

Family and domain databases

CDDicd03863 M14_CPD_II, 1 hit
InterProiView protein in InterPro
IPR008969 CarboxyPept-like_regulatory
IPR034224 M14_CPD_II
IPR015567 Pept_M14B_carboxypept_D2
IPR000834 Peptidase_M14
PANTHERiPTHR11532:SF73 PTHR11532:SF73, 3 hits
PfamiView protein in Pfam
PF00246 Peptidase_M14, 3 hits
PRINTSiPR00765 CRBOXYPTASEA
SMARTiView protein in SMART
SM00631 Zn_pept, 3 hits
SUPFAMiSSF49464 SSF49464, 3 hits
PROSITEiView protein in PROSITE
PS00132 CARBOXYPEPT_ZN_1, 2 hits
PS00133 CARBOXYPEPT_ZN_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCBPD_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O89001
Secondary accession number(s): Q5SVH8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: July 27, 2011
Last modified: October 16, 2019
This is version 160 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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