Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 135 (08 May 2019)
Sequence version 1 (01 Nov 1998)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Calcineurin-binding protein cabin-1

Gene

Cabin1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be required for replication-independent chromatin assembly (By similarity). May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin.By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Calcineurin-binding protein cabin-1
Alternative name(s):
Calcineurin inhibitor
Short name:
CAIN
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cabin1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
620263 Cabin1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001062761 – 2182Calcineurin-binding protein cabin-1Add BLAST2182

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei10PhosphoserineBy similarity1
Modified residuei11PhosphoserineBy similarity1
Modified residuei12PhosphothreonineBy similarity1
Modified residuei20PhosphoserineBy similarity1
Modified residuei673PhosphoserineBy similarity1
Modified residuei1439PhosphoserineBy similarity1
Modified residuei2003PhosphoserineCombined sources1
Modified residuei2113PhosphothreonineBy similarity1
Modified residuei2116PhosphothreonineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Activated through PKC-mediated hyperphosphorylation.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O88480

PRoteomics IDEntifications database

More...
PRIDEi
O88480

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O88480

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O88480

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with prominent expression in neurons.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a complex that includes at least ASF1A, CABIN1, HIRA, histone H3.3 and UBN1 (By similarity).

Interacts with MEF2B (By similarity).

Interacts with calcineurin.

By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000001659

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O88480

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati36 – 69TPR 1Add BLAST34
Repeati90 – 123TPR 2Add BLAST34
Repeati125 – 157TPR 3Add BLAST33
Repeati615 – 648TPR 4Add BLAST34
Repeati1055 – 1088TPR 5Add BLAST34
Repeati1106 – 1139TPR 6Add BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2078 – 2115Required for interaction with calcineurinAdd BLAST38

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFFG Eukaryota
ENOG410XY91 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111281

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O88480

KEGG Orthology (KO)

More...
KOi
K17613

Database of Orthologous Groups

More...
OrthoDBi
56555at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O88480

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13839 MEF2_binding, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033053 Hir3/CABIN1
IPR015134 MEF2-bd
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

The PANTHER Classification System

More...
PANTHERi
PTHR15502 PTHR15502, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09047 MEF2_binding, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48452 SSF48452, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50005 TPR, 4 hits
PS50293 TPR_REGION, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

O88480-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIRIAALNAS STIEDDHEGS FKSHKIQTKE AQEAEAFALY HKALDLQKHD
60 70 80 90 100
RFEESAKAYH ELLEARLLRE AVSSGDEKEG LKHPGLILKY STYKNLAQLA
110 120 130 140 150
AQREDLETAM EFYLEAVMLD STDVNLWYKI GHVALRLIRL PLARHAFEEG
160 170 180 190 200
LRCNPDHWPC LDNLITVLYT LSDYTTCLYF ICKALEKDCR YSKGLVLKEK
210 220 230 240 250
IFEEQPCLRK DSLRMFLKCD MSVHEVSVNA AETQAIVDEA LGLRKKRQAL
260 270 280 290 300
IVREKEPDLK LVQPIPFFTW KCLGESLLAM YNHLTTCEPP RPSLGKRIDL
310 320 330 340 350
SDYQDPSQLL APSIVVTPVS VVQPSPVCTN PTVAVAEPVL SYTSVTTTSF
360 370 380 390 400
PLHSPGLLDT GTPMGDVSGG DKSKKGVKRK KTLEESGETA KRRSARVRNT
410 420 430 440 450
KCKKEEKVDF QGLLVKFLPS RLRKLDPEEE DDPFNNYEVQ SEAKLESFSN
460 470 480 490 500
VGPHRLSFDS ATFMESEKQD VHAFLMENLT NGGVLELMMR YLKSMGHKFL
510 520 530 540 550
LKWPPGLAEV VLSVYHSWRR HSTSLPNPLL RDCSNKHIKD MMLMSLSCME
560 570 580 590 600
LQLDQWLLTK GRSSTVSPRN CPAGVVTGRF GPDFPGTHCL GDLLQLSFAS
610 620 630 640 650
SQRDLFEDGW LEFVVRVYWL KARFLALQGD MEQALENYDI CTEILQSSTA
660 670 680 690 700
LQAQAGAEQR DIVIRLPNLH NDSIVSLEEI DKNLKSLERC QSLEEIQRLF
710 720 730 740 750
EAGDYKAVVQ LLRPTLCTSG FDRAKHLEFM TSIPERPAQL LLLQDSLLRL
760 770 780 790 800
EEHRQCFECS DVALNEAVQQ MLNSSDSAAK EEWAATVTQL LLGMEQALSS
810 820 830 840 850
DSRGSILKES SSPTGLVRLT NNLIQVIDCS MAVQEEPKEP YVSSVLPWII
860 870 880 890 900
LHRIIWQEED TFRSLCHQQQ LQNPTEEGIS EMPMLPSSLM LLNTAHEYLG
910 920 930 940 950
RRSWCCNSDG ALLRFYVHVL QKELAASASE DTHPYKEELE TALEQCFYCL
960 970 980 990 1000
YSFPSKKSKA RYLEEHSAQQ VDLTWEDALF MFEYFKPKTL PEFDSYKTST
1010 1020 1030 1040 1050
VSADLANLLK RIATIVPRTE KPALSMDKVS AYIEGTSAEV PCLPDGADPA
1060 1070 1080 1090 1100
PPVLNELYYL LADYHFKNKE QSKAIKFYMH DICICPNRFD SWAGMALARA
1110 1120 1130 1140 1150
SRIQDKLNSN ELKSDGPIWR HATPVLNCFR RALEIDSSNL SLWIEYGTMS
1160 1170 1180 1190 1200
YALHSFASRQ LKQWRAELPP EVVQQMEDRR DSMLETARHC FTSAAHCEGD
1210 1220 1230 1240 1250
GDEEEWLIHY MLGKVAEKQQ QPPTVYLLHY RQAGHYLHEE AARYPKKIHY
1260 1270 1280 1290 1300
HNPPELAMEA LEVYFRLHAS ILKLLGKPDS GVSAEVLVSF MKEAAEGPFA
1310 1320 1330 1340 1350
RGEEKNTPKA SEKEKACLVD EDSHSSAGTL PGPGASLPSS SGPGLTSPPY
1360 1370 1380 1390 1400
TATPIDHDYV KCKKPRQQAT PDDRSQDSTA VALSDSSSTQ DFFNEPTSLL
1410 1420 1430 1440 1450
DGSRKLLPEK RISGLSAQAG PSGKDLPGPT EERGKTEESL ESTEAFRVVE
1460 1470 1480 1490 1500
PSVQKPVADS SASAYIPSKP AVSTPPPWDG KKRSDPLGEP VAFPQGLPAG
1510 1520 1530 1540 1550
AEEQRQFLTE QCIASFCLCL SRFPQHYKSL YRLAFLYTYS KTHRNLQWAR
1560 1570 1580 1590 1600
DVLLGSSIPW QQLQHMPAQG LFCERNKTNF FNGIWRIPVD EIDRPGSFAW
1610 1620 1630 1640 1650
HMNRSIVLLL KVLAQLRDHS TLLKVSSMLQ RTPDQGKKYL RDADRQVLAQ
1660 1670 1680 1690 1700
RAFILTVKVL EDTLSELAEG LEHPGSKACG LSGARMTTDV SHKASPEDGQ
1710 1720 1730 1740 1750
ESLPHPKKLP LADGSGPGPE PGGKVGPLHQ LPVATDTRDN TEQGGEPKDK
1760 1770 1780 1790 1800
ERPPVGPTEP MDTGETAARH PDLEPTPRLL PGRPPRDRGP ESRSAELSLE
1810 1820 1830 1840 1850
ELSISTRQQP APLVPSPVTP TTAAPTTMGA RAAGHPEEAP PRPNRKRKLL
1860 1870 1880 1890 1900
QDTESGKTLL LDAYRVWQQG QKAMAYDLSR IEKIMSETYM LIKQVDEETA
1910 1920 1930 1940 1950
LEQAVKFCQV HLGAAAQRQA SGDAPTTPKH PKDSRENFFP ATVAPSAPDT
1960 1970 1980 1990 2000
TAPDALQRPS DSHLKPGLAA AITCPPSASA STPDPGIPQP HRPEAVPSRA
2010 2020 2030 2040 2050
PLSPDGEEVS GVTEGPSFLS QEPRHSHQMK MAATGPLAEQ HCWPVEAACQ
2060 2070 2080 2090 2100
TGAEPTFSQA TSTKVPSSGS TQTPESHQGK TESSRAKSRL LPNMPKLVIP
2110 2120 2130 2140 2150
SATTKFPPEI TVTPPTPTLL SPKGSISEET KQKLKSAILS AQSAANVRKE
2160 2170 2180
SLCQPALEVL ETSSQESSLE SETDEDDDFM DV
Length:2,182
Mass (Da):242,813
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2904C335AB3F440A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V650G3V650_RAT
Calcineurin binding protein 1, isof...
Cabin1 rCG_60929
2,182Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2Q6J0A0A1W2Q6J0_RAT
Calcineurin-binding protein cabin-1
Cabin1
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF061947 mRNA Translation: AAC40176.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T14320

NCBI Reference Sequences

More...
RefSeqi
NP_446027.2, NM_053575.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
94165

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:94165

UCSC genome browser

More...
UCSCi
RGD:620263 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF061947 mRNA Translation: AAC40176.1
PIRiT14320
RefSeqiNP_446027.2, NM_053575.2

3D structure databases

SMRiO88480
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000001659

PTM databases

iPTMnetiO88480
PhosphoSitePlusiO88480

Proteomic databases

PaxDbiO88480
PRIDEiO88480

Genome annotation databases

GeneIDi94165
KEGGirno:94165
UCSCiRGD:620263 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23523
RGDi620263 Cabin1

Phylogenomic databases

eggNOGiENOG410IFFG Eukaryota
ENOG410XY91 LUCA
HOGENOMiHOG000111281
InParanoidiO88480
KOiK17613
OrthoDBi56555at2759
PhylomeDBiO88480

Enzyme and pathway databases

ReactomeiR-RNO-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF)

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O88480

Family and domain databases

CDDicd13839 MEF2_binding, 1 hit
Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR033053 Hir3/CABIN1
IPR015134 MEF2-bd
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR15502 PTHR15502, 1 hit
PfamiView protein in Pfam
PF09047 MEF2_binding, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 4 hits
PS50293 TPR_REGION, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCABIN_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O88480
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: May 8, 2019
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again