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Protein

Transcriptional regulatory protein TdiR

Gene

tdiR

Organism
Thauera aromatica
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Member of the two-component regulatory system TdiR/TdiS, which probably regulates transcription of toluene catabolic genes (bss operon). Binds to DNA.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi165 – 184H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation, Two-component regulatory system

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein TdiR
Gene namesi
Name:tdiR
OrganismiThauera aromatica
Taxonomic identifieri59405 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaRhodocyclalesZoogloeaceaeThauera

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004188711 – 227Transcriptional regulatory protein TdiRAdd BLAST227

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei604-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by TdiS.By similarity

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliO87940
SMRiO87940
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 125Response regulatoryPROSITE-ProRule annotationAdd BLAST115
Domaini141 – 206HTH luxR-typePROSITE-ProRule annotationAdd BLAST66

Family and domain databases

CDDicd06170 LuxR_C_like, 1 hit
cd00156 REC, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011006 CheY-like_superfamily
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR001789 Sig_transdc_resp-reg_receiver
IPR000792 Tscrpt_reg_LuxR_C
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00196 GerE, 1 hit
PF00072 Response_reg, 1 hit
PRINTSiPR00038 HTHLUXR
SMARTiView protein in SMART
SM00421 HTH_LUXR, 1 hit
SM00448 REC, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF52172 SSF52172, 1 hit
PROSITEiView protein in PROSITE
PS00622 HTH_LUXR_1, 1 hit
PS50043 HTH_LUXR_2, 1 hit
PS50110 RESPONSE_REGULATORY, 1 hit

Sequencei

Sequence statusi: Complete.

O87940-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQATKTGNAS TVFVVDDEAS VRDSLTWLLN SISLDVRTFE SAKDFLDADI
60 70 80 90 100
SCTHGCVVLD VRMQNVSGLQ LQQALSERGF KLPIIFLSAY GDAQMGAQAV
110 120 130 140 150
KKGAFDFLQK PYRNQDLLDA VNAALALNRE MADKQNEKQK HLDLLATLSQ
160 170 180 190 200
REMEILDKVV AGSSSKEIAK LLGISYKTVE AHRGRIISKL GLKSTGDLMH
210 220
FVMRGSSHCS DCGRQPLPGS SPCRPAA
Length:227
Mass (Da):24,759
Last modified:November 1, 1998 - v1
Checksum:iE741F397A850D807
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001848 Genomic DNA Translation: CAA05049.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001848 Genomic DNA Translation: CAA05049.1

3D structure databases

ProteinModelPortaliO87940
SMRiO87940
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd06170 LuxR_C_like, 1 hit
cd00156 REC, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011006 CheY-like_superfamily
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR001789 Sig_transdc_resp-reg_receiver
IPR000792 Tscrpt_reg_LuxR_C
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF00196 GerE, 1 hit
PF00072 Response_reg, 1 hit
PRINTSiPR00038 HTHLUXR
SMARTiView protein in SMART
SM00421 HTH_LUXR, 1 hit
SM00448 REC, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF52172 SSF52172, 1 hit
PROSITEiView protein in PROSITE
PS00622 HTH_LUXR_1, 1 hit
PS50043 HTH_LUXR_2, 1 hit
PS50110 RESPONSE_REGULATORY, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTDIR_THAAR
AccessioniPrimary (citable) accession number: O87940
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: November 1, 1998
Last modified: October 25, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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