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Entry version 71 (17 Jun 2020)
Sequence version 1 (01 Nov 1998)
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Protein
Submitted name:

C-di-GMP phosphodiesterase A

Gene

pdeA2

Organism
Komagataeibacter xylinus (Gluconacetobacter xylinus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
C-di-GMP phosphodiesterase AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pdeA2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiKomagataeibacter xylinus (Gluconacetobacter xylinus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri28448 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesAcetobacteraceaeKomagataeibacter

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini30 – 100PASInterPro annotationAdd BLAST71
Domaini346 – 478GGDEFInterPro annotationAdd BLAST133
Domaini487 – 741EALInterPro annotationAdd BLAST255

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01948, EAL, 1 hit
cd01949, GGDEF, 1 hit
cd00130, PAS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.450, 1 hit
3.30.450.40, 1 hit
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012226, Diguanyl_cyclase/Pdiesterase
IPR001633, EAL_dom
IPR035919, EAL_sf
IPR029016, GAF-like_dom_sf
IPR000160, GGDEF_dom
IPR029787, Nucleotide_cyclase
IPR001610, PAC
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00563, EAL, 1 hit
PF00990, GGDEF, 1 hit
PF13426, PAS_9, 1 hit

PIRSF; a whole-protein classification database

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PIRSFi
PIRSF005925, Dos, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00052, EAL, 1 hit
SM00267, GGDEF, 1 hit
SM00086, PAC, 1 hit
SM00091, PAS, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF141868, SSF141868, 1 hit
SSF55073, SSF55073, 1 hit
SSF55785, SSF55785, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00254, GGDEF, 1 hit
TIGR00229, sensory_box, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50883, EAL, 1 hit
PS50887, GGDEF, 1 hit
PS50112, PAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O87376-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPAQVRKMIL HGAVGRADVL EFTVDQPKIS ADVLLSAMEQ AIDPMVVIDE
60 70 80 90 100
HNLIIFFNAA AEKIWGCSRE EVMGRNVSCL VPEPERDRHD DYINRNRETG
110 120 130 140 150
VGRIVGTSRE VEFRRANGEY VCGELSISRV QVNDCGKIYY IAVMKDVTEQ
160 170 180 190 200
SRQRKILVLQ NDVLQALASD MSIQEVGDLL CRRADSFVPG AVGALMLIDP
210 220 230 240 250
SRRLSVSASP SMPKRYRAAL DSMQLTPEQL EMLRANPAGS NTVVWDGYAS
260 270 280 290 300
LARSLGLERC CSSTIISRTG QVMGVFALYL RGDEADLAWA QRVVSTSMPF
310 320 330 340 350
CALAIEQSET RQHIAQLSNF DSLTGLLNRT SLHNIIERLI MRGGDSQFSL
360 370 380 390 400
FMVDIDRFRD INDALGHVNA DRFLIEIGRR IRHLVKDEYI VSRSGGDEFI
410 420 430 440 450
IVVPECSHER AEKFAENLIN AIARPLQVGE NTLSISCCVG ISTFPANGPD
460 470 480 490 500
SESLLSHADA ATRQAKEDGR GLFRFAGQEK NQVAQDRLVL GSALRDSLSK
510 520 530 540 550
GMLNLNYQPQ VETMTGGLYG VEALSRWHHP TLGNIYPSRF IAVAEETGQI
560 570 580 590 600
EAIGRWSLEE ACSQMVKWDR DGVRVPTVAV NLSAVHFRNR GLPEHIANLL
610 620 630 640 650
KHHGLTPDRL TVEITESVMM DSSSETEEVL HAIRRLDVGL SMDDFGTGYS
660 670 680 690 700
SLSRLTRLPL TEIKIDRSFI NDFEHDTNAQ AVTMAVIGIG SRLGMTVVTE
710 720 730 740 750
GVETEQQWRL LEELHCDVMQ GYLFSKPLPP AELEKWFRER QERGSFLIPT

TA
Length:752
Mass (Da):83,790
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC001A3E09C418B74
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF052518 Genomic DNA Translation: AAC61686.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF052518 Genomic DNA Translation: AAC61686.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

CDDicd01948, EAL, 1 hit
cd01949, GGDEF, 1 hit
cd00130, PAS, 1 hit
Gene3Di3.20.20.450, 1 hit
3.30.450.40, 1 hit
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR012226, Diguanyl_cyclase/Pdiesterase
IPR001633, EAL_dom
IPR035919, EAL_sf
IPR029016, GAF-like_dom_sf
IPR000160, GGDEF_dom
IPR029787, Nucleotide_cyclase
IPR001610, PAC
IPR000014, PAS
IPR035965, PAS-like_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
PfamiView protein in Pfam
PF00563, EAL, 1 hit
PF00990, GGDEF, 1 hit
PF13426, PAS_9, 1 hit
PIRSFiPIRSF005925, Dos, 1 hit
SMARTiView protein in SMART
SM00052, EAL, 1 hit
SM00267, GGDEF, 1 hit
SM00086, PAC, 1 hit
SM00091, PAS, 1 hit
SUPFAMiSSF141868, SSF141868, 1 hit
SSF55073, SSF55073, 1 hit
SSF55785, SSF55785, 1 hit
TIGRFAMsiTIGR00254, GGDEF, 1 hit
TIGR00229, sensory_box, 1 hit
PROSITEiView protein in PROSITE
PS50883, EAL, 1 hit
PS50887, GGDEF, 1 hit
PS50112, PAS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO87376_KOMXY
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O87376
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: June 17, 2020
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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