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Entry version 99 (07 Apr 2021)
Sequence version 1 (01 Nov 1998)
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Protein
Submitted name:

Putative replication initiation protein Rep

Gene

rep

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative replication initiation protein RepImported
Submitted name:
Replication initiator proteinImported
Submitted name:
Replication proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:repImported
Synonyms:repAImported
ORF Names:BN1321_460001Imported, ERS072840_02903Imported, GO706_16250Imported, SAMEA103891571_02742Imported, SAP014A_024Imported, SAP015H_001Imported, SAP068A_001Imported, SAP069A_027Imported, SAP079A_026Imported, SAP080A_044Imported, SAP082A_019Imported, VRA0001Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid SAP014AImported
Plasmid SAP015BImported
Plasmid SAP068AImported
Plasmid SAP069AImported
Plasmid SAP079AImported
Plasmid SAP080AImported
Plasmid SAP082AImported
Plasmid pLW043Imported
Plasmid pN315GImported
Plasmid pSK41Imported
Plasmid plw043Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiStaphylococcus aureusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1280 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000505270 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000433276 Componenti: Unassembled WGS sequence
  • UP000039437 Componenti: Unassembled WGS sequence
  • UP000242625 Componenti: Plasmid plw043
  • UP000069800 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini14 – 89RepA_NInterPro annotationAdd BLAST76
Domaini218 – 301Bac_RepA_CInterPro annotationAdd BLAST84

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili116 – 136Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041151, Bac_RepA_C
IPR010724, RepA_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18008, Bac_RepA_C, 1 hit
PF06970, RepA_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O87367-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKQFFTVEE NYKERFYQLP KVFFTNPNYK DLSNDAKIAY AILRDRLQLS
60 70 80 90 100
IKNNWIDTEG NIYFIYTVAD LEVILNCGNK KITKIKKELE NVDLLIQKRQ
110 120 130 140 150
GLNKPNLLYL LKPAITKNDI YEIDKAENEV EALQDKEVSK GHVQKCQKDT
160 170 180 190 200
SRNVKRTRLE MSKGHTNDTD FIDTDFIDTE SNDMNNMNDT NQHSNHSNHF
210 220 230 240 250
SNIHDKESLK YIELQELPEL IKSYINNFSY EEVKSIKSVI LKAKKSFNNK
260 270 280 290 300
YDTFYMLEDI DEELLLVLKR FKGYLVKKQE KVANMEGYLM RSIIAELEEM
310
HSTIMRRKNM ENNPLSLFN
Length:319
Mass (Da):37,689
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEFC551B9EB3DECA9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF051917 Genomic DNA Translation: AAC61944.1
AE017171 Genomic DNA Translation: AAQ17124.1
GQ900421 Genomic DNA Translation: ACZ68636.1
GQ900422 Genomic DNA Translation: ACZ68717.1
GQ900379 Genomic DNA Translation: ADA61331.1
GQ900432 Genomic DNA Translation: ADA62096.1
GQ900433 Genomic DNA Translation: ADA62167.1
GQ900434 Genomic DNA Translation: ADA62191.1
GQ900504 Genomic DNA Translation: ADA62815.1
AP012550 Genomic DNA Translation: BAP94550.1
CAIIXB010000019 Genomic DNA Translation: CAC9483185.1
CVOQ01000041 Genomic DNA Translation: CRI20811.1
FGEC01000043 Genomic DNA Translation: CXO38015.1
WPRC01000334 Genomic DNA Translation: MVI40197.1

NCBI Reference Sequences

More...
RefSeqi
NP_863615.1, NC_005024.1
NP_877980.1, NC_005054.1
WP_000043161.1, NZ_WWCF01000338.1
YP_002790910.1, NC_012547.1
YP_006937644.1, NC_013320.1
YP_006938302.1, NC_013338.1
YP_006938382.1, NC_013339.1
YP_006938489.1, NC_013342.1
YP_006938559.1, NC_013343.1
YP_006938584.1, NC_013344.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AVG65299; AVG65299; RK64_14000
CRI20811; CRI20811; BN1321_460001
CXO38015; CXO38015; ERS072840_02903

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
59697409

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1280.3527.peg.141

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051917 Genomic DNA Translation: AAC61944.1
AE017171 Genomic DNA Translation: AAQ17124.1
GQ900421 Genomic DNA Translation: ACZ68636.1
GQ900422 Genomic DNA Translation: ACZ68717.1
GQ900379 Genomic DNA Translation: ADA61331.1
GQ900432 Genomic DNA Translation: ADA62096.1
GQ900433 Genomic DNA Translation: ADA62167.1
GQ900434 Genomic DNA Translation: ADA62191.1
GQ900504 Genomic DNA Translation: ADA62815.1
AP012550 Genomic DNA Translation: BAP94550.1
CAIIXB010000019 Genomic DNA Translation: CAC9483185.1
CVOQ01000041 Genomic DNA Translation: CRI20811.1
FGEC01000043 Genomic DNA Translation: CXO38015.1
WPRC01000334 Genomic DNA Translation: MVI40197.1
RefSeqiNP_863615.1, NC_005024.1
NP_877980.1, NC_005054.1
WP_000043161.1, NZ_WWCF01000338.1
YP_002790910.1, NC_012547.1
YP_006937644.1, NC_013320.1
YP_006938302.1, NC_013338.1
YP_006938382.1, NC_013339.1
YP_006938489.1, NC_013342.1
YP_006938559.1, NC_013343.1
YP_006938584.1, NC_013344.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAVG65299; AVG65299; RK64_14000
CRI20811; CRI20811; BN1321_460001
CXO38015; CXO38015; ERS072840_02903
GeneIDi59697409
PATRICifig|1280.3527.peg.141

Family and domain databases

InterProiView protein in InterPro
IPR041151, Bac_RepA_C
IPR010724, RepA_N
PfamiView protein in Pfam
PF18008, Bac_RepA_C, 1 hit
PF06970, RepA_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO87367_STAAU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O87367
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: April 7, 2021
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

PlasmidImported
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