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UniProtKB - O85862 (O85862_NOVAR)

Entry version 69 (12 Aug 2020)
Sequence version 1 (01 Nov 1998)
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Protein
Submitted name:

Probably methylase/helicase

Gene

orf235

Organism
Novosphingobium aromaticivorans (Sphingomonas aromaticivorans)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseImported, Hydrolase, MethyltransferaseImported, Transferase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Probably methylase/helicaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:orf235Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pNL1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNovosphingobium aromaticivorans (Sphingomonas aromaticivorans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri48935 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Novosphingobium

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini402 – 720AAA_34InterPro annotationAdd BLAST319
Domaini894 – 1147Helicase_C_4InterPro annotationAdd BLAST254

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SBNO family.ARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR027417, P-loop_NTPase
IPR029063, SAM-dependent_MTases
IPR026937, SBNO_Helicase_C_dom
IPR026741, SNO
IPR039187, SNO_AAA

The PANTHER Classification System

More...PANTHERi		PTHR12706, PTHR12706, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13872, AAA_34, 1 hit
PF13871, Helicase_C_4, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit
SSF53335, SSF53335, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O85862-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCRRSAADLT ILPETSMTAT ISGSSAILGA ARTLAAKLLL AIPIDRAALT 
        60         70         80         90        100
EAMTESSGGN DAAGAWTQRE SFEALEVALA MAIPELVGRM DAGAAIGTLE 
       110        120        130        140        150
ALARELPTHT VRSEDQIAFQ QFSTPPALAC LAVHLARLGS EDIFLEPSAG 
       160        170        180        190        200
TGIIAALARG AVKQFLLNEL EPTRAELLEG LFPGSSVYRH DGAKIAALLA 
       210        220        230        240        250
GTARPSVIVM NPPFSVSQSR GEDQNTAARH LRAALDHLLP GGRVVAIMPD 
       260        270        280        290        300
WFAESARGGE VYRRTLEGAR VVMSLRLDKG GYAKHGTGIA VRLLVIDKVP 
       310        320        330        340        350
GETSVSTINR ASVSELFAAL GPIPPRAALR VASPAAVVRP KLSLFRSVKS 
       360        370        380        390        400
GPARPVIVRA PQTNEVRPVA YQVLEEAAAM GEQRGVYADY RPSRVVIPEA 
       410        420        430        440        450
GEHPSHLVES AAMASIAAPK PGYIPCLPER TVTARLLSAA QLETVIYAGE 
       460        470        480        490        500
AWSRDLHGRF SQTAGEVALK EDPEGQLYRT GFFLGDGTGA GKGRQAAACI 
       510        520        530        540        550
LDQWLKGNRR HIWISKNAPL LEDAQRDWTA IGGLPSDIID LARWKIGEEI 
       560        570        580        590        600
TAPEGILFVP YGTLRSARVE DTRLDQIVRW ASPAFEGVIV FDEAHEMGGV 
       610        620        630        640        650
AGGEGALGQK QGSLQGIAGV LLQNTLPRAR VLYASATGAS DVNNLAYAVR 
       660        670        680        690        700
LGLWGPGTAF ANREQFISEI RDGGIAAMEL VARDLKASGL YLARALSFAG 
       710        720        730        740        750
IEYDILRHDL SIDQIAIYDT YCEAWTIIHQ NLEAALELTG VVDGLENRTL 
       760        770        780        790        800
NSGAKAAARS RFEGTKQRFF AQVLLSLKLP SIFPAIDEHL AQDESVVVQL 
       810        820        830        840        850
VSTAESILNR RLNELDPEER EALELDLSPR EAIVDYLTRA FPTRQMEEYV 
       860        870        880        890        900
DELGDVRSRP MWDQAGNPVH NPQAEAAREQ LIEHICAMPP IPTALDALLE 
       910        920        930        940        950
HYGVSAVAEV TGRSKRLVRD GSGQQRLESR SPRTNLAETT AFMTGAKRIL 
       960        970        980        990       1000
VFSDAGGTGR SYHASLDAKN QQRRVHFLLE PGWRADRAIQ GLGRTHRTHQ 
      1010       1020       1030       1040       1050
ACPPLFRPVT TDCKGEARFT STIARRLDAL GALTRGQRQT GGQGMFDAAD 
      1060       1070       1080       1090       1100
NLESAYAKHA LHDWYGLLAT GKLKSTSLKE FQAMSGLELT DQDGVLREDL 
      1110       1120       1130       1140       1150
PPIQRWLNRI LAMKIAVQNA IFDEFLTLVE TRVSAAKEAG TFDIGVETVA 
      1160       1170       1180       1190       1200
AETCEVLSDT VIRTDPVTGA TSHLLELSLT QRRKLLALER VLKMASYENK 
      1210       1220       1230       1240       1250
PLFLRNAKSG KVALAIPAPS HMDEEGELIR RFELVRPLRS EYILAGRLDE 
      1260       1270       1280       1290       1300
TAWEPVAQTK FSALWEAEYA ADENQLVTET VFLATGLLLP IWGALPKEDL 
      1310       1320       1330       1340       1350
TVNRIVDKSG ASWLGRHVHD LYVDATLEKL GVSRKAQTDP AKIAQAILGG 
      1360       1370       1380       1390       1400
GTWKAPHPLN FTVRTSRVNG ARRIEIVGAE AARIPELKAM GCFTEIIAYK 
      1410       1420 
TRVFVPTDKA EAILQAMTGP GTTPD
Length:1,425
Mass (Da):154,439
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i46C045580A373919
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF079317 Genomic DNA Translation: AAD03877.1

Protein sequence database of the Protein Information Resource

More...PIRi		T31153

NCBI Reference Sequences

More...RefSeqi		NP_049081.1, NC_002033.1
WP_010890899.1, NC_002033.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		1238389

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF079317 Genomic DNA Translation: AAD03877.1
PIRiT31153
RefSeqiNP_049081.1, NC_002033.1
WP_010890899.1, NC_002033.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi1238389

Family and domain databases

InterProiView protein in InterPro
IPR027417, P-loop_NTPase
IPR029063, SAM-dependent_MTases
IPR026937, SBNO_Helicase_C_dom
IPR026741, SNO
IPR039187, SNO_AAA
PANTHERiPTHR12706, PTHR12706, 2 hits
PfamiView protein in Pfam
PF13872, AAA_34, 1 hit
PF13871, Helicase_C_4, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
SSF53335, SSF53335, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO85862_NOVAR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O85862
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: August 12, 2020
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

PlasmidImported
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