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Entry version 111 (02 Dec 2020)
Sequence version 1 (01 Nov 1998)
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Protein
Submitted name:

SecD/SecF fusion protein

Gene

secD

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, TranslocationARBA annotation, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
CTRA272561:G1G18-476-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SecD/SecF fusion proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:secDImported
Synonyms:secFImported
Ordered Locus Names:CT_448Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiChlamydia trachomatis (strain D/UW-3/Cx)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000431 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei906 – 925HelicalSequence analysisAdd BLAST20
Transmembranei930 – 950HelicalSequence analysisAdd BLAST21
Transmembranei956 – 980HelicalSequence analysisAdd BLAST25
Transmembranei1001 – 1022HelicalSequence analysisAdd BLAST22
Transmembranei1034 – 1057HelicalSequence analysisAdd BLAST24
Transmembranei1085 – 1105HelicalSequence analysisAdd BLAST21
Transmembranei1232 – 1249HelicalSequence analysisAdd BLAST18
Transmembranei1256 – 1280HelicalSequence analysisAdd BLAST25
Transmembranei1286 – 1309HelicalSequence analysisAdd BLAST24
Transmembranei1339 – 1358HelicalSequence analysisAdd BLAST20
Transmembranei1364 – 1391HelicalSequence analysisAdd BLAST28

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili232 – 252Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004081_0_0_0

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O84454

Identification of Orthologs from Complete Genome Data

More...
OMAi
WRMAVIL

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005791, SecD
IPR022813, SecD/SecF_arch_bac
IPR022645, SecD/SecF_bac
IPR005665, SecF_bac

The PANTHER Classification System

More...
PANTHERi
PTHR30081, PTHR30081, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02355, SecD_SecF, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01755, SECFTRNLCASE

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00916, 2A0604s01, 1 hit
TIGR00966, 3a0501s07, 1 hit
TIGR01129, secD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O84454-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRNFKRNLS IIILVFALAL YHVLPTCLYY SRPLNRKIDG REARKIIERF
60 70 80 90 100
TRQVSDARND LTLRVAKILS TLKLRGDIKQ HPSIPGVVNV HFPLAEDAAL
110 120 130 140 150
FIDNVVHGEP SVPVKSARLY VVGSSEFTGE TVVQISGSLV TSLTEKDLSF
160 170 180 190 200
VSYEDKDVTV SQELENLATN LFIESERPCE CGYYSLWDSM PIEKVIYVTR
210 220 230 240 250
NICSGLRLLP ARKTQAFLSR CLGTERDFTA FLARLEKALQ HEEVKEAREE
260 270 280 290 300
LKDASYLLHS RNLRWNSISP KVVGNVVDCS ELSPCFSSMS LTADGKLLFH
310 320 330 340 350
FDAEVAANRQ QLVGNERLDL ERLFAMEKQH IATRLNRSVE GTEFGFAVRL
360 370 380 390 400
RDEAASGKIV LQGHRVCQRI VEHLTALVLN RPIAETCDLS TENFPVYGRE
410 420 430 440 450
PLDSDALGCF IFSPERSCRH FSKGSVYIVF KGLRSIVAKY EHAGAEEAAL
460 470 480 490 500
LQHDLQNLYA CFIHTDAVSW SLGEDRVLEI KEPLQRVIRI WGEEFVQSFG
510 520 530 540 550
KASLEVRDVR DRLAVVNRIE KTQHAELVRW DEQYRQAQCS MNPRVRLRAA
560 570 580 590 600
IPHKNIFFEN LKLNIRKYSR GEHVLRFGTD FVGGKQIRIA FRDHQGNLLT
610 620 630 640 650
DKAGIDKVSD ELYARLNKLG VSEVGMQREG DHIQVSVPGA AGISSADILG
660 670 680 690 700
TSKMSFHVVN EQFSSRSPLR YEVQTFLDYL WFTARSLDEC SPQAINRLAG
710 720 730 740 750
ALFHGDNGSA PANVRVAVEK LREAGLSFSK ELEGGSASLD TQYSMIAIEK
760 770 780 790 800
ESREQVNPLM IVFRNHALEG ASLKNIRPEF AVGEGYVLNF GVKDKATFSD
810 820 830 840 850
GRETPVQQFH AWTSKFCQEG VSGTKNGLFS GGRGWRMAVV LDGYVISDPV
860 870 880 890 900
LNVPLKDHAS VSGNFSYREV HRLAADLKSG AMSFIPEILS EEVVSPELGS
910 920 930 940 950
SQRVQGILSV VLGLVVLIVL MSVYYRFGGV IASIAVLLNL LLIWASMQYL
960 970 980 990 1000
DAPLTLSGLA GIILAMGMAV DANVLVFERI REEYLLTRSL SESVEAGYKK
1010 1020 1030 1040 1050
AFSAIFDSNL TTILASALLL MLDTGPIKGF ALTLIIGIFS SMFTALFMTK
1060 1070 1080 1090 1100
FFFVIWVQKT RETQLHMMNK FIGIKHNFLK ECKRLWVVSG VVLVLGCVGL
1110 1120 1130 1140 1150
GFGAWDSVFG MDFKGGYALT LDSDVCEYNP EQMCSVLRKR FQQIGLSSRD
1160 1170 1180 1190 1200
YRVRRADSSE KVKIYLSQNA LDRVEQIEGA GSEQKGSDYH LARVLQVLSD
1210 1220 1230 1240 1250
SGSSTTSMVF DASRGSWFKV SGQLSNKMRT QAVIALFGAL GIILFYVSLR
1260 1270 1280 1290 1300
FEWRYAFSAI CALMHDLLAT CAVLVALHFF LQRIQIDLQA IGALMTVLGY
1310 1320 1330 1340 1350
SLNNTLIIFD RIREDRREKL FTPMPILIND ALQKTLGRTV MTTATTLSVL
1360 1370 1380 1390 1400
VILLFVGGGS IFNFAFIMTV GILLGTLSSL YIAPPLLLFM VRKEEQNSLR
Length:1,400
Mass (Da):156,516
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i09400F968AD18406
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE001273 Genomic DNA Translation: AAC68047.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A71514

NCBI Reference Sequences

More...
RefSeqi
NP_219961.1, NC_000117.1
WP_009871805.1, NC_000117.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC68047; AAC68047; CT_448

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
884222

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ctr:CT_448

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|272561.5.peg.484

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA Translation: AAC68047.1
PIRiA71514
RefSeqiNP_219961.1, NC_000117.1
WP_009871805.1, NC_000117.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAAC68047; AAC68047; CT_448
GeneIDi884222
KEGGictr:CT_448
PATRICifig|272561.5.peg.484

Phylogenomic databases

HOGENOMiCLU_004081_0_0_0
InParanoidiO84454
OMAiWRMAVIL

Enzyme and pathway databases

BioCyciCTRA272561:G1G18-476-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR005791, SecD
IPR022813, SecD/SecF_arch_bac
IPR022645, SecD/SecF_bac
IPR005665, SecF_bac
PANTHERiPTHR30081, PTHR30081, 2 hits
PfamiView protein in Pfam
PF02355, SecD_SecF, 2 hits
PRINTSiPR01755, SECFTRNLCASE
TIGRFAMsiTIGR00916, 2A0604s01, 1 hit
TIGR00966, 3a0501s07, 1 hit
TIGR01129, secD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO84454_CHLTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O84454
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: December 2, 2020
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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