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UniProtKB - O84454 (O84454_CHLTR)

Entry version 111 (02 Dec 2020)
Sequence version 1 (01 Nov 1998)
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Protein
Submitted name:

SecD/SecF fusion protein

Gene

secD

Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, TranslocationARBA annotation, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		CTRA272561:G1G18-476-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SecD/SecF fusion proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:secDImported
Synonyms:secFImported
Ordered Locus Names:CT_448Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiChlamydia trachomatis (strain D/UW-3/Cx)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272561 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000431 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei906 – 925HelicalSequence analysisAdd BLAST20
Transmembranei930 – 950HelicalSequence analysisAdd BLAST21
Transmembranei956 – 980HelicalSequence analysisAdd BLAST25
Transmembranei1001 – 1022HelicalSequence analysisAdd BLAST22
Transmembranei1034 – 1057HelicalSequence analysisAdd BLAST24
Transmembranei1085 – 1105HelicalSequence analysisAdd BLAST21
Transmembranei1232 – 1249HelicalSequence analysisAdd BLAST18
Transmembranei1256 – 1280HelicalSequence analysisAdd BLAST25
Transmembranei1286 – 1309HelicalSequence analysisAdd BLAST24
Transmembranei1339 – 1358HelicalSequence analysisAdd BLAST20
Transmembranei1364 – 1391HelicalSequence analysisAdd BLAST28

GO - Cellular componenti

Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili232 – 252Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004081_0_0_0

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O84454

Identification of Orthologs from Complete Genome Data

More...OMAi		WRMAVIL

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR005791, SecD
IPR022813, SecD/SecF_arch_bac
IPR022645, SecD/SecF_bac
IPR005665, SecF_bac

The PANTHER Classification System

More...PANTHERi		PTHR30081, PTHR30081, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02355, SecD_SecF, 2 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01755, SECFTRNLCASE

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00916, 2A0604s01, 1 hit
TIGR00966, 3a0501s07, 1 hit
TIGR01129, secD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O84454-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRNFKRNLS IIILVFALAL YHVLPTCLYY SRPLNRKIDG REARKIIERF 
        60         70         80         90        100
TRQVSDARND LTLRVAKILS TLKLRGDIKQ HPSIPGVVNV HFPLAEDAAL 
       110        120        130        140        150
FIDNVVHGEP SVPVKSARLY VVGSSEFTGE TVVQISGSLV TSLTEKDLSF 
       160        170        180        190        200
VSYEDKDVTV SQELENLATN LFIESERPCE CGYYSLWDSM PIEKVIYVTR 
       210        220        230        240        250
NICSGLRLLP ARKTQAFLSR CLGTERDFTA FLARLEKALQ HEEVKEAREE 
       260        270        280        290        300
LKDASYLLHS RNLRWNSISP KVVGNVVDCS ELSPCFSSMS LTADGKLLFH 
       310        320        330        340        350
FDAEVAANRQ QLVGNERLDL ERLFAMEKQH IATRLNRSVE GTEFGFAVRL 
       360        370        380        390        400
RDEAASGKIV LQGHRVCQRI VEHLTALVLN RPIAETCDLS TENFPVYGRE 
       410        420        430        440        450
PLDSDALGCF IFSPERSCRH FSKGSVYIVF KGLRSIVAKY EHAGAEEAAL 
       460        470        480        490        500
LQHDLQNLYA CFIHTDAVSW SLGEDRVLEI KEPLQRVIRI WGEEFVQSFG 
       510        520        530        540        550
KASLEVRDVR DRLAVVNRIE KTQHAELVRW DEQYRQAQCS MNPRVRLRAA 
       560        570        580        590        600
IPHKNIFFEN LKLNIRKYSR GEHVLRFGTD FVGGKQIRIA FRDHQGNLLT 
       610        620        630        640        650
DKAGIDKVSD ELYARLNKLG VSEVGMQREG DHIQVSVPGA AGISSADILG 
       660        670        680        690        700
TSKMSFHVVN EQFSSRSPLR YEVQTFLDYL WFTARSLDEC SPQAINRLAG 
       710        720        730        740        750
ALFHGDNGSA PANVRVAVEK LREAGLSFSK ELEGGSASLD TQYSMIAIEK 
       760        770        780        790        800
ESREQVNPLM IVFRNHALEG ASLKNIRPEF AVGEGYVLNF GVKDKATFSD 
       810        820        830        840        850
GRETPVQQFH AWTSKFCQEG VSGTKNGLFS GGRGWRMAVV LDGYVISDPV 
       860        870        880        890        900
LNVPLKDHAS VSGNFSYREV HRLAADLKSG AMSFIPEILS EEVVSPELGS 
       910        920        930        940        950
SQRVQGILSV VLGLVVLIVL MSVYYRFGGV IASIAVLLNL LLIWASMQYL 
       960        970        980        990       1000
DAPLTLSGLA GIILAMGMAV DANVLVFERI REEYLLTRSL SESVEAGYKK 
      1010       1020       1030       1040       1050
AFSAIFDSNL TTILASALLL MLDTGPIKGF ALTLIIGIFS SMFTALFMTK 
      1060       1070       1080       1090       1100
FFFVIWVQKT RETQLHMMNK FIGIKHNFLK ECKRLWVVSG VVLVLGCVGL 
      1110       1120       1130       1140       1150
GFGAWDSVFG MDFKGGYALT LDSDVCEYNP EQMCSVLRKR FQQIGLSSRD 
      1160       1170       1180       1190       1200
YRVRRADSSE KVKIYLSQNA LDRVEQIEGA GSEQKGSDYH LARVLQVLSD 
      1210       1220       1230       1240       1250
SGSSTTSMVF DASRGSWFKV SGQLSNKMRT QAVIALFGAL GIILFYVSLR 
      1260       1270       1280       1290       1300
FEWRYAFSAI CALMHDLLAT CAVLVALHFF LQRIQIDLQA IGALMTVLGY 
      1310       1320       1330       1340       1350
SLNNTLIIFD RIREDRREKL FTPMPILIND ALQKTLGRTV MTTATTLSVL 
      1360       1370       1380       1390       1400
VILLFVGGGS IFNFAFIMTV GILLGTLSSL YIAPPLLLFM VRKEEQNSLR
Length:1,400
Mass (Da):156,516
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i09400F968AD18406
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE001273 Genomic DNA Translation: AAC68047.1

Protein sequence database of the Protein Information Resource

More...PIRi		A71514

NCBI Reference Sequences

More...RefSeqi		NP_219961.1, NC_000117.1
WP_009871805.1, NC_000117.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC68047; AAC68047; CT_448

Database of genes from NCBI RefSeq genomes

More...GeneIDi		884222

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ctr:CT_448

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|272561.5.peg.484

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001273 Genomic DNA Translation: AAC68047.1
PIRiA71514
RefSeqiNP_219961.1, NC_000117.1
WP_009871805.1, NC_000117.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAAC68047; AAC68047; CT_448
GeneIDi884222
KEGGictr:CT_448
PATRICifig|272561.5.peg.484

Phylogenomic databases

HOGENOMiCLU_004081_0_0_0
InParanoidiO84454
OMAiWRMAVIL

Enzyme and pathway databases

BioCyciCTRA272561:G1G18-476-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR005791, SecD
IPR022813, SecD/SecF_arch_bac
IPR022645, SecD/SecF_bac
IPR005665, SecF_bac
PANTHERiPTHR30081, PTHR30081, 2 hits
PfamiView protein in Pfam
PF02355, SecD_SecF, 2 hits
PRINTSiPR01755, SECFTRNLCASE
TIGRFAMsiTIGR00916, 2A0604s01, 1 hit
TIGR00966, 3a0501s07, 1 hit
TIGR01129, secD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO84454_CHLTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O84454
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: December 2, 2020
This is version 111 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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