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Protein

RNA polymerase sigma-54 factor

Gene

rpoN

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi356 – 375H-T-H motifSequence analysisAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Nucleotidyltransferase, Sigma factor, Transferase
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma-54 factor
Gene namesi
Name:rpoN
Ordered Locus Names:TP_0111
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002055451 – 475RNA polymerase sigma-54 factorAdd BLAST475

Proteomic databases

PRIDEiO83149

Interactioni

Protein-protein interaction databases

IntActiO83149, 2 interactors
STRINGi243276.TP0111

Structurei

3D structure databases

ProteinModelPortaliO83149
SMRiO83149
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi458 – 466RPON box9

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi2 – 14Gln-richAdd BLAST13

Sequence similaritiesi

Belongs to the sigma-54 factor family.Curated

Phylogenomic databases

eggNOGiENOG4105DTW Bacteria
COG1508 LUCA
KOiK03092
OMAiVTTQKFM

Family and domain databases

Gene3Di1.10.10.1330, 1 hit
InterProiView protein in InterPro
IPR000394 RNA_pol_sigma_54
IPR007046 RNA_pol_sigma_54_core-bd
IPR007634 RNA_pol_sigma_54_DNA-bd
IPR038709 RpoN_core-bd_sf
PANTHERiPTHR32248 PTHR32248, 1 hit
PfamiView protein in Pfam
PF00309 Sigma54_AID, 1 hit
PF04963 Sigma54_CBD, 1 hit
PF04552 Sigma54_DBD, 1 hit
PIRSFiPIRSF000774 RpoN, 1 hit
TIGRFAMsiTIGR02395 rpoN_sigma, 1 hit
PROSITEiView protein in PROSITE
PS00717 SIGMA54_1, 1 hit
PS00718 SIGMA54_2, 1 hit
PS50044 SIGMA54_3, 1 hit

Sequencei

Sequence statusi: Complete.

O83149-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQLVQQQRL VLNQRLVHGL CLLQLSRGDL KTEVLRAVQR NPLLEIRPSS
60 70 80 90 100
ARRTGKACYL SLGDRRERMR ARDRFQQLLE NQPDKQVDNI RAVLREQVFY
110 120 130 140 150
QKHEAIVLDL ACAFIQMLDD HGFFSISPAI FQNMCGSMPT ALQEKIPQAI
160 170 180 190 200
ALIQRLEPQG CAVFNFKESL AVQARLRFER FSDPLYRCVI NLLTHHSELL
210 220 230 240 250
FCSDNMCDGR VSVHALTTQI NSMGLCVQKV SSNDVKDILL LIKELHPFPG
260 270 280 290 300
KCVSNAQRAD TNMLLEPDVL ITKTAHGFVT QINCTGIPTV VFRNDYCMHS
310 320 330 340 350
KAAEKNHALK ACMHDALSLV SMLSYRERTL LDIAKTIVHY QCGFFDHGPA
360 370 380 390 400
KLTPLRMTDV AHRTGLSVST VSRIVRDKWL QYGSQHFSLR YFFSPRVLST
410 420 430 440 450
EEYRDRSSLG QNYPSSPHSK VSVKYRISRL IQEVRTQRIS LSDRRIAQLL
460 470
GEQGIKCARR TVNKYRSELR TCSSS
Length:475
Mass (Da):54,280
Last modified:November 1, 1998 - v1
Checksum:i2464059A019A6190
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000520 Genomic DNA Translation: AAC65101.1
PIRiF71364

Genome annotation databases

EnsemblBacteriaiAAC65101; AAC65101; TP_0111
KEGGitpa:TP_0111

Similar proteinsi

Entry informationi

Entry nameiRP54_TREPA
AccessioniPrimary (citable) accession number: O83149
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1998
Last modified: June 20, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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