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Entry version 141 (07 Apr 2021)
Sequence version 2 (01 Dec 2000)
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Protein

GTP-binding protein ERG

Gene

ERG

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Has a crucial role in plant growth and development, possibly by influencing mitochondrial division.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi160 – 167GTPSequence analysis8
Nucleotide bindingi207 – 211GTPSequence analysis5
Nucleotide bindingi279 – 282GTPSequence analysis4

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
LigandGTP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GTP-binding protein ERG
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ERG
Ordered Locus Names:At1g30960
ORF Names:F17F8.15
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G30960

The Arabidopsis Information Resource

More...
TAIRi
locus:2015771, AT1G30960

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001800801 – 437GTP-binding protein ERGAdd BLAST437

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei111PhosphoserineCombined sources1
Modified residuei112PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O82653

PRoteomics IDEntifications database

More...
PRIDEi
O82653

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
220576

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O82653

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O82653, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O82653, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
25218, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT1G30960.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O82653

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini152 – 333Era-type GPROSITE-ProRule annotationAdd BLAST182
Domaini361 – 437KH type-2Add BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni160 – 167G1PROSITE-ProRule annotation8
Regioni186 – 190G2PROSITE-ProRule annotation5
Regioni207 – 210G3PROSITE-ProRule annotation4
Regioni279 – 282G4PROSITE-ProRule annotation4
Regioni309 – 311G5PROSITE-ProRule annotation3

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.PROSITE-ProRule annotationCurated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1423, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_038009_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O82653

Identification of Orthologs from Complete Genome Data

More...
OMAi
YVIDHRL

Database of Orthologous Groups

More...
OrthoDBi
586738at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O82653

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04163, Era, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.300.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00367, GTPase_Era, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030388, G_ERA_dom
IPR006073, GTP-bd
IPR005662, GTP-bd_Era
IPR015946, KH_dom-like_a/b
IPR004044, KH_dom_type_2
IPR009019, KH_sf_prok-type
IPR027417, P-loop_NTPase
IPR005225, Small_GTP-bd_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07650, KH_2, 1 hit
PF01926, MMR_HSR1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 1 hit
SSF54814, SSF54814, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00436, era, 1 hit
TIGR00231, small_GTP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51713, G_ERA, 1 hit
PS50823, KH_TYPE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O82653-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKAFRSLRIL ISISRTTTKT TPRNPHQAQN FLRRFYSAQP NLDEPTSINE
60 70 80 90 100
DGSSSDSVFD SSQYPIDDSN VDSVKKPKEA TWDKGYRERV NKAFFGNLTE
110 120 130 140 150
KGKVKVAEEE SSEDDEDSVD RSRILAKALL EAALESPDEE LGEGEVREED
160 170 180 190 200
QKSLNVGIIG PPNAGKSSLT NFMVGTKVAA ASRKTNTTTH EVLGVLTKGD
210 220 230 240 250
TQVCFFDTPG LMLKKSGYGY KDIKARVQNA WTSVDLFDVL IVMFDVHRHL
260 270 280 290 300
MSPDSRVVRL IKYMGEEENP KQKRVLCMNK VDLVEKKKDL LKVAEEFQDL
310 320 330 340 350
PAYERYFMIS GLKGSGVKDL SQYLMDQAVK KPWEEDAFTM SEEVLKNISL
360 370 380 390 400
EVVRERLLDH VHQEIPYGLE HRLVDWKELR DGSLRIEQHL ITPKLSQRKI
410 420 430
LVGKGGCKIG RIGIEANEEL RRIMNRKVHL ILQVKLK
Length:437
Mass (Da):49,671
Last modified:December 1, 2000 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5F1AA1B32A50EE4D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti40P → A in CAA76979 (PubMed:9768362).Curated1
Sequence conflicti252 – 255Missing in CAA76979 (PubMed:9768362).Curated4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC000107 Genomic DNA Translation: AAF98187.1
CP002684 Genomic DNA Translation: AEE31297.1
BT015076 mRNA Translation: AAT71948.1
BT015910 mRNA Translation: AAU95446.1
Y17969 Genomic DNA Translation: CAA76979.1

Protein sequence database of the Protein Information Resource

More...
PIRi
C86435

NCBI Reference Sequences

More...
RefSeqi
NP_174383.1, NM_102835.5

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G30960.1; AT1G30960.1; AT1G30960

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
839983

Gramene; a comparative resource for plants

More...
Gramenei
AT1G30960.1; AT1G30960.1; AT1G30960

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G30960

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000107 Genomic DNA Translation: AAF98187.1
CP002684 Genomic DNA Translation: AEE31297.1
BT015076 mRNA Translation: AAT71948.1
BT015910 mRNA Translation: AAU95446.1
Y17969 Genomic DNA Translation: CAA76979.1
PIRiC86435
RefSeqiNP_174383.1, NM_102835.5

3D structure databases

SMRiO82653
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi25218, 1 interactor
STRINGi3702.AT1G30960.1

PTM databases

iPTMnetiO82653

Proteomic databases

PaxDbiO82653
PRIDEiO82653
ProteomicsDBi220576

Genome annotation databases

EnsemblPlantsiAT1G30960.1; AT1G30960.1; AT1G30960
GeneIDi839983
GrameneiAT1G30960.1; AT1G30960.1; AT1G30960
KEGGiath:AT1G30960

Organism-specific databases

AraportiAT1G30960
TAIRilocus:2015771, AT1G30960

Phylogenomic databases

eggNOGiKOG1423, Eukaryota
HOGENOMiCLU_038009_2_0_1
InParanoidiO82653
OMAiYVIDHRL
OrthoDBi586738at2759
PhylomeDBiO82653

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O82653

Gene expression databases

ExpressionAtlasiO82653, baseline and differential
GenevisibleiO82653, AT

Family and domain databases

CDDicd04163, Era, 1 hit
Gene3Di3.30.300.20, 1 hit
HAMAPiMF_00367, GTPase_Era, 1 hit
InterProiView protein in InterPro
IPR030388, G_ERA_dom
IPR006073, GTP-bd
IPR005662, GTP-bd_Era
IPR015946, KH_dom-like_a/b
IPR004044, KH_dom_type_2
IPR009019, KH_sf_prok-type
IPR027417, P-loop_NTPase
IPR005225, Small_GTP-bd_dom
PfamiView protein in Pfam
PF07650, KH_2, 1 hit
PF01926, MMR_HSR1, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
SSF54814, SSF54814, 1 hit
TIGRFAMsiTIGR00436, era, 1 hit
TIGR00231, small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51713, G_ERA, 1 hit
PS50823, KH_TYPE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiERG_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O82653
Secondary accession number(s): Q6DBE6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: December 1, 2000
Last modified: April 7, 2021
This is version 141 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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