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Entry version 130 (07 Oct 2020)
Sequence version 1 (01 Nov 1998)
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Protein

Phosphomethylpyrimidine synthase, chloroplastic

Gene

THIC

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

[4Fe-4S] cluster1 Publication1 PublicationNote: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: thiamine diphosphate biosynthesis

This protein is involved in the pathway thiamine diphosphate biosynthesis, which is part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the pathway thiamine diphosphate biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei228SubstrateBy similarity1
Binding sitei257SubstrateBy similarity1
Binding sitei286SubstrateBy similarity1
Binding sitei322SubstrateBy similarity1
Binding sitei422SubstrateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi426Zinc1 Publication1
Binding sitei449SubstrateBy similarity1
Metal bindingi490Zinc1 Publication1
Metal bindingi570Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Metal bindingi573Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1
Metal bindingi578Iron-sulfur (4Fe-4S-S-AdoMet)By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLyase
Biological processThiamine biosynthesis
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT2G29630-MONOMER
MetaCyc:AT2G29630-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
4.1.99.17, 399

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00060

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphomethylpyrimidine synthase, chloroplastic (EC:4.1.99.17)
Alternative name(s):
Hydroxymethylpyrimidine phosphate synthase
Short name:
HMP-P synthase
Short name:
HMP-phosphate synthase
Short name:
HMPP synthase
Protein PYRIMIDINE REQUIRING
Thiamine biosynthesis protein ThiC
Short name:
Protein THIAMINE C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:THIC
Synonyms:PY
Ordered Locus Names:At2g29630
ORF Names:T27A16.27
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G29630

The Arabidopsis Information Resource

More...
TAIRi
locus:2060604, AT2G29630

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Albino (white leaves) and lethal under normal culture conditions, probably due to an impairment in thiamine biosynthesis.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 54ChloroplastCuratedAdd BLAST54
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000041551855 – 644Phosphomethylpyrimidine synthase, chloroplasticAdd BLAST590

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O82392

PRoteomics IDEntifications database

More...
PRIDEi
O82392

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
246437

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O82392

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Strongly expressed in cotyledons, leaves, flowers and siliques, and, to a lower extent, in roots (PubMed:18048325, PubMed:25014715). Expressed in all green tissues, but not in roots, seeds, and petals (PubMed:23341335).3 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

First detected in five-days seedlings. In seedlings, mostly present at the root tips and in the jointed section between the hypocotyl and root. In two-leaves seedlings, expressed in leaves, cotyledons and vascular bundles of hypocotyls, and very weakly, in the roots. In flowers, detected in sepals, filaments and pistil tips, but not in petals. Later accumulates in the jointed region between the silique and silique stem, and in the tips of siliques. Decreasing expression during seed development (PubMed:25014715).3 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Circadian-regulation (PubMed:23341335). Down-regulated by extrinsic thiamine, via a vitamin B1 derivative thiamine pyrophosphate (TPP)-sensing riboswitch regulation. Detected in both dark and light grown seedlings; increased progressively after transfer of etiolated seedlings to light. Up-regulated by salt, osmotic stress and abscisic acid (PubMed:22214485).6 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O82392, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O82392, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
2863, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT2G29630.2

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1644
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O82392

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni342 – 344Substrate bindingBy similarity3
Regioni383 – 386Substrate bindingBy similarity4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ThiC family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRQ4, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013181_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O82392

KEGG Orthology (KO)

More...
KOi
K03147

Database of Orthologous Groups

More...
OrthoDBi
394937at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O82392

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.540, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00089, ThiC, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037509, ThiC
IPR038521, ThiC/Bza_sf
IPR002817, ThiC/BzaA/B

The PANTHER Classification System

More...
PANTHERi
PTHR30557, PTHR30557, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01964, ThiC_Rad_SAM, 1 hit

Structure-Function Linkage Database

More...
SFLDi
SFLDF00407, phosphomethylpyrimidine_syntha, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00190, thiC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O82392-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASVHCTLM SVVCNNKNHS ARPKLPNSSL LPGFDVVVQA AATRFKKETT
60 70 80 90 100
TTRATLTFDP PTTNSERAKQ RKHTIDPSSP DFQPIPSFEE CFPKSTKEHK
110 120 130 140 150
EVVHEESGHV LKVPFRRVHL SGGEPAFDNY DTSGPQNVNA HIGLAKLRKE
160 170 180 190 200
WIDRREKLGT PRYTQMYYAK QGIITEEMLY CATREKLDPE FVRSEVARGR
210 220 230 240 250
AIIPSNKKHL ELEPMIVGRK FLVKVNANIG NSAVASSIEE EVYKVQWATM
260 270 280 290 300
WGADTIMDLS TGRHIHETRE WILRNSAVPV GTVPIYQALE KVDGIAENLN
310 320 330 340 350
WEVFRETLIE QAEQGVDYFT IHAGVLLRYI PLTAKRLTGI VSRGGSIHAK
360 370 380 390 400
WCLAYHKENF AYEHWDDILD ICNQYDVALS IGDGLRPGSI YDANDTAQFA
410 420 430 440 450
ELLTQGELTR RAWEKDVQVM NEGPGHVPMH KIPENMQKQL EWCNEAPFYT
460 470 480 490 500
LGPLTTDIAP GYDHITSAIG AANIGALGTA LLCYVTPKEH LGLPNRDDVK
510 520 530 540 550
AGVIAYKIAA HAADLAKQHP HAQAWDDALS KARFEFRWMD QFALSLDPMT
560 570 580 590 600
AMSFHDETLP ADGAKVAHFC SMCGPKFCSM KITEDIRKYA EENGYGSAEE
610 620 630 640
AIRQGMDAMS EEFNIAKKTI SGEQHGEVGG EIYLPESYVK AAQK
Length:644
Mass (Da):71,987
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD1051F98A0200D21
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8B279A0A1P8B279_ARATH
ThiaminC
THIC PY, PYRIMIDINE REQUIRING, thiaminC, At2g29630, T27A16.27
479Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC005496 Genomic DNA Translation: AAC35232.1
CP002685 Genomic DNA Translation: AEC08281.1
CP002685 Genomic DNA Translation: AEC08282.1
CP002685 Genomic DNA Translation: AEC08283.1
AY092989 mRNA Translation: AAM12988.1
AY128756 mRNA Translation: AAM91156.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F84698

NCBI Reference Sequences

More...
RefSeqi
NP_001189634.1, NM_001202705.1
NP_180524.1, NM_128517.4
NP_850135.1, NM_179804.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G29630.1; AT2G29630.1; AT2G29630
AT2G29630.2; AT2G29630.2; AT2G29630
AT2G29630.3; AT2G29630.3; AT2G29630

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
817513

Gramene; a comparative resource for plants

More...
Gramenei
AT2G29630.1; AT2G29630.1; AT2G29630
AT2G29630.2; AT2G29630.2; AT2G29630
AT2G29630.3; AT2G29630.3; AT2G29630

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G29630

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005496 Genomic DNA Translation: AAC35232.1
CP002685 Genomic DNA Translation: AEC08281.1
CP002685 Genomic DNA Translation: AEC08282.1
CP002685 Genomic DNA Translation: AEC08283.1
AY092989 mRNA Translation: AAM12988.1
AY128756 mRNA Translation: AAM91156.1
PIRiF84698
RefSeqiNP_001189634.1, NM_001202705.1
NP_180524.1, NM_128517.4
NP_850135.1, NM_179804.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4N7QX-ray1.60A72-644[»]
4S25X-ray1.45A72-644[»]
4S26X-ray1.85A/B72-644[»]
4S27X-ray1.27A72-644[»]
4S28X-ray1.25A72-644[»]
4S29X-ray1.38A72-644[»]
SMRiO82392
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi2863, 1 interactor
STRINGi3702.AT2G29630.2

PTM databases

iPTMnetiO82392

Proteomic databases

PaxDbiO82392
PRIDEiO82392
ProteomicsDBi246437

Genome annotation databases

EnsemblPlantsiAT2G29630.1; AT2G29630.1; AT2G29630
AT2G29630.2; AT2G29630.2; AT2G29630
AT2G29630.3; AT2G29630.3; AT2G29630
GeneIDi817513
GrameneiAT2G29630.1; AT2G29630.1; AT2G29630
AT2G29630.2; AT2G29630.2; AT2G29630
AT2G29630.3; AT2G29630.3; AT2G29630
KEGGiath:AT2G29630

Organism-specific databases

AraportiAT2G29630
TAIRilocus:2060604, AT2G29630

Phylogenomic databases

eggNOGiENOG502QRQ4, Eukaryota
HOGENOMiCLU_013181_2_1_1
InParanoidiO82392
KOiK03147
OrthoDBi394937at2759
PhylomeDBiO82392

Enzyme and pathway databases

UniPathwayiUPA00060
BioCyciARA:AT2G29630-MONOMER
MetaCyc:AT2G29630-MONOMER
BRENDAi4.1.99.17, 399

Miscellaneous databases

Protein Ontology

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PROi
PR:O82392

Gene expression databases

ExpressionAtlasiO82392, baseline and differential
GenevisibleiO82392, AT

Family and domain databases

Gene3Di3.20.20.540, 1 hit
HAMAPiMF_00089, ThiC, 1 hit
InterProiView protein in InterPro
IPR037509, ThiC
IPR038521, ThiC/Bza_sf
IPR002817, ThiC/BzaA/B
PANTHERiPTHR30557, PTHR30557, 1 hit
PfamiView protein in Pfam
PF01964, ThiC_Rad_SAM, 1 hit
SFLDiSFLDF00407, phosphomethylpyrimidine_syntha, 1 hit
TIGRFAMsiTIGR00190, thiC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTHIC_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O82392
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: November 1, 1998
Last modified: October 7, 2020
This is version 130 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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