UniProtKB - O82318 (Y2579_ARATH)
Protein
Probably inactive leucine-rich repeat receptor-like protein kinase At2g25790
Gene
At2g25790
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 717 | ATPPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 697 – 705 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein kinase activity Source: InterPro
Keywordsi
Molecular function | Receptor |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Probably inactive leucine-rich repeat receptor-like protein kinase At2g25790 |
Gene namesi | Ordered Locus Names:At2g25790 ORF Names:F17H15.18 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G25790 |
TAIRi | locus:2043540, AT2G25790 |
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Single-pass type I membrane protein By similarity
Endoplasmic reticulum
- endoplasmic reticulum Source: TAIR
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 30 – 634 | ExtracellularSequence analysisAdd BLAST | 605 | |
Transmembranei | 635 – 655 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 656 – 960 | CytoplasmicSequence analysisAdd BLAST | 305 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 29 | Sequence analysisAdd BLAST | 29 | |
ChainiPRO_0000389454 | 30 – 960 | Probably inactive leucine-rich repeat receptor-like protein kinase At2g25790Add BLAST | 931 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 23 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 70 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 83 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 103 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 108 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 129 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 134 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 191 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 228 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 252 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 324 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 362 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 372 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 537 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 580 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 600 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 692 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 834 | PhosphotyrosineBy similarity | 1 |
Keywords - PTMi
Glycoprotein, PhosphoproteinProteomic databases
PaxDbi | O82318 |
PRIDEi | O82318 |
ProteomicsDBi | 243149 |
Expressioni
Gene expression databases
ExpressionAtlasi | O82318, baseline and differential |
Genevisiblei | O82318, AT |
Interactioni
Binary interactionsi
O82318
With | #Exp. | IntAct |
---|---|---|
At2g02780 [C0LGJ9] | 2 | EBI-20661246,EBI-20651541 |
Protein-protein interaction databases
BioGRIDi | 2473, 29 interactors |
IntActi | O82318, 29 interactors |
STRINGi | 3702.AT2G25790.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 71 – 96 | LRR 1Add BLAST | 26 | |
Repeati | 97 – 120 | LRR 2Add BLAST | 24 | |
Repeati | 122 – 146 | LRR 3Add BLAST | 25 | |
Repeati | 149 – 168 | LRR 4Add BLAST | 20 | |
Repeati | 169 – 194 | LRR 5Add BLAST | 26 | |
Repeati | 196 – 216 | LRR 6Add BLAST | 21 | |
Repeati | 217 – 240 | LRR 7Add BLAST | 24 | |
Repeati | 241 – 264 | LRR 8Add BLAST | 24 | |
Repeati | 265 – 288 | LRR 9Add BLAST | 24 | |
Repeati | 290 – 312 | LRR 10Add BLAST | 23 | |
Repeati | 313 – 336 | LRR 11Add BLAST | 24 | |
Repeati | 338 – 360 | LRR 12Add BLAST | 23 | |
Repeati | 361 – 384 | LRR 13Add BLAST | 24 | |
Repeati | 386 – 408 | LRR 14Add BLAST | 23 | |
Repeati | 409 – 432 | LRR 15Add BLAST | 24 | |
Repeati | 434 – 454 | LRR 16Add BLAST | 21 | |
Repeati | 455 – 477 | LRR 17Add BLAST | 23 | |
Repeati | 478 – 501 | LRR 18Add BLAST | 24 | |
Repeati | 503 – 525 | LRR 19Add BLAST | 23 | |
Repeati | 526 – 549 | LRR 20Add BLAST | 24 | |
Repeati | 550 – 573 | LRR 21Add BLAST | 24 | |
Repeati | 575 – 598 | LRR 22Add BLAST | 24 | |
Domaini | 691 – 953 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 263 |
Domaini
The protein kinase domain is predicted to be catalytically inactive. Lacks the conserved Asp active site at position 699, which is replaced by a Ser residue.
Sequence similaritiesi
Keywords - Domaini
Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QRRF, Eukaryota |
HOGENOMi | CLU_000288_22_1_1 |
InParanoidi | O82318 |
OMAi | WIDSSID |
OrthoDBi | 826997at2759 |
PhylomeDBi | O82318 |
Family and domain databases
Gene3Di | 3.80.10.10, 3 hits |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR013210, LRR_N_plant-typ IPR000719, Prot_kinase_dom |
Pfami | View protein in Pfam PF00560, LRR_1, 1 hit PF13855, LRR_8, 3 hits PF08263, LRRNT_2, 1 hit PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 9 hits |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O82318-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTSHHHHHP PYLITTLFFL FLNFSCLHAN ELELLLSFKS SIQDPLKHLS
60 70 80 90 100
SWSYSSTNDV CLWSGVVCNN ISRVVSLDLS GKNMSGQILT AATFRLPFLQ
110 120 130 140 150
TINLSNNNLS GPIPHDIFTT SSPSLRYLNL SNNNFSGSIP RGFLPNLYTL
160 170 180 190 200
DLSNNMFTGE IYNDIGVFSN LRVLDLGGNV LTGHVPGYLG NLSRLEFLTL
210 220 230 240 250
ASNQLTGGVP VELGKMKNLK WIYLGYNNLS GEIPYQIGGL SSLNHLDLVY
260 270 280 290 300
NNLSGPIPPS LGDLKKLEYM FLYQNKLSGQ IPPSIFSLQN LISLDFSDNS
310 320 330 340 350
LSGEIPELVA QMQSLEILHL FSNNLTGKIP EGVTSLPRLK VLQLWSNRFS
360 370 380 390 400
GGIPANLGKH NNLTVLDLST NNLTGKLPDT LCDSGHLTKL ILFSNSLDSQ
410 420 430 440 450
IPPSLGMCQS LERVRLQNNG FSGKLPRGFT KLQLVNFLDL SNNNLQGNIN
460 470 480 490 500
TWDMPQLEML DLSVNKFFGE LPDFSRSKRL KKLDLSRNKI SGVVPQGLMT
510 520 530 540 550
FPEIMDLDLS ENEITGVIPR ELSSCKNLVN LDLSHNNFTG EIPSSFAEFQ
560 570 580 590 600
VLSDLDLSCN QLSGEIPKNL GNIESLVQVN ISHNLLHGSL PFTGAFLAIN
610 620 630 640 650
ATAVEGNIDL CSENSASGLR PCKVVRKRST KSWWLIITST FAAFLAVLVS
660 670 680 690 700
GFFIVLVFQR THNVLEVKKV EQEDGTKWET QFFDSKFMKS FTVNTILSSL
710 720 730 740 750
KDQNVLVDKN GVHFVVKEVK KYDSLPEMIS DMRKLSDHKN ILKIVATCRS
760 770 780 790 800
ETVAYLIHED VEGKRLSQVL SGLSWERRRK IMKGIVEALR FLHCRCSPAV
810 820 830 840 850
VAGNLSPENI VIDVTDEPRL CLGLPGLLCM DAAYMAPETR EHKEMTSKSD
860 870 880 890 900
IYGFGILLLH LLTGKCSSSN EDIESGVNGS LVKWARYSYS NCHIDTWIDS
910 920 930 940 950
SIDTSVHQRE IVHVMNLALK CTAIDPQERP CTNNVLQALE STSSSSSSCT
960
TYLSKILSLA
Sequence cautioni
The sequence CAA23395 differs from that shown. Reason: Frameshift.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005395 Genomic DNA Translation: AAC42251.1 CP002685 Genomic DNA Translation: AEC07753.1 FJ708700 mRNA Translation: ACN59295.1 F20108 mRNA Translation: CAA23395.1 Frameshift. |
PIRi | G84652 |
RefSeqi | NP_180150.1, NM_128139.3 |
Genome annotation databases
EnsemblPlantsi | AT2G25790.1; AT2G25790.1; AT2G25790 |
GeneIDi | 817121 |
Gramenei | AT2G25790.1; AT2G25790.1; AT2G25790 |
KEGGi | ath:AT2G25790 |
Similar proteinsi
Cross-referencesi
Web resourcesi
PlantP kinase Classification PPC |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005395 Genomic DNA Translation: AAC42251.1 CP002685 Genomic DNA Translation: AEC07753.1 FJ708700 mRNA Translation: ACN59295.1 F20108 mRNA Translation: CAA23395.1 Frameshift. |
PIRi | G84652 |
RefSeqi | NP_180150.1, NM_128139.3 |
3D structure databases
SMRi | O82318 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 2473, 29 interactors |
IntActi | O82318, 29 interactors |
STRINGi | 3702.AT2G25790.1 |
Proteomic databases
PaxDbi | O82318 |
PRIDEi | O82318 |
ProteomicsDBi | 243149 |
Genome annotation databases
EnsemblPlantsi | AT2G25790.1; AT2G25790.1; AT2G25790 |
GeneIDi | 817121 |
Gramenei | AT2G25790.1; AT2G25790.1; AT2G25790 |
KEGGi | ath:AT2G25790 |
Organism-specific databases
Araporti | AT2G25790 |
TAIRi | locus:2043540, AT2G25790 |
Phylogenomic databases
eggNOGi | ENOG502QRRF, Eukaryota |
HOGENOMi | CLU_000288_22_1_1 |
InParanoidi | O82318 |
OMAi | WIDSSID |
OrthoDBi | 826997at2759 |
PhylomeDBi | O82318 |
Miscellaneous databases
PROi | PR:O82318 |
Gene expression databases
ExpressionAtlasi | O82318, baseline and differential |
Genevisiblei | O82318, AT |
Family and domain databases
Gene3Di | 3.80.10.10, 3 hits |
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR013210, LRR_N_plant-typ IPR000719, Prot_kinase_dom |
Pfami | View protein in Pfam PF00560, LRR_1, 1 hit PF13855, LRR_8, 3 hits PF08263, LRRNT_2, 1 hit PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 9 hits |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y2579_ARATH | |
Accessioni | O82318Primary (citable) accession number: O82318 Secondary accession number(s): Q42355 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 24, 2009 |
Last sequence update: | November 1, 1998 | |
Last modified: | August 12, 2020 | |
This is version 136 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families