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Entry version 138 (07 Apr 2021)
Sequence version 1 (01 Nov 1998)
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Protein

Leucine-rich repeat receptor-like serine/threonine-protein kinase SKM1

Gene

SKM1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor with a serine/threonine-protein kinase activity (By similarity). Together with SKM2, LRR-rich receptor-like kinase (LRR-RLK) required for male fertility by the perception of CLE43 and CLE45 peptides and the transduction of their promoting action in pollen tubes, especially under relatively high temperature (at 30 degrees Celsius), thus conferring tolerance against high temperature probably through the maintenance of mitochondrial activity (PubMed:23910659). Seems to not be involved in the perception of CLE45 peptide in roots (PubMed:27354416).By similarity2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei717ATPPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi697 – 705ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • peptide binding Source: UniProtKB
  • peptide receptor activity Source: UniProtKB
  • protein serine kinase activity Source: UniProtKB-EC
  • protein threonine kinase activity Source: UniProtKB-EC

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor, Transferase
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Leucine-rich repeat receptor-like serine/threonine-protein kinase SKM1Curated (EC:2.7.11.1Curated)
Alternative name(s):
Protein STERILITY-REGULATING KINASE MEMBER 11 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SKM11 Publication
Ordered Locus Names:At2g25790Imported
ORF Names:F17H15.18Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G25790

The Arabidopsis Information Resource

More...
TAIRi
locus:2043540, AT2G25790

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini30 – 634ExtracellularCuratedAdd BLAST605
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei635 – 655HelicalSequence analysisAdd BLAST21
Topological domaini656 – 960CytoplasmicCuratedAdd BLAST305

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Insensitivity of pollen tubes to CLE43 and, partially, to CLE45 peptides-mediated growth stimulation (PubMed:23910659). Pollen tubes of plants missing both SKM1 and SKM2 are fully insensitive to CLE45 peptides (PubMed:23910659). Reduced seed production at 30 degrees Celsius, but not at 22 degrees Celsius (PubMed:23910659).1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi717K → E in KDSKM1; lost kinase activity (kinase-dead). High-temperature exposure (HTE) mediated reduction in seeds number. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 29Sequence analysisAdd BLAST29
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000038945430 – 960Leucine-rich repeat receptor-like serine/threonine-protein kinase SKM1Add BLAST931

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi61 ↔ 68By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi70N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi83N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi103N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi108N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi129N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi134N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi191N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi228N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi252N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi324N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi362N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi372N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi537N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi580N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi600N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei692PhosphothreonineBy similarity1
Modified residuei834PhosphotyrosineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O82318

PRoteomics IDEntifications database

More...
PRIDEi
O82318

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
243149

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in pollen grains and roots vascular tissues (PubMed:23910659). Present in roots (PubMed:27354416).2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In roots, restricted to the mature vasculature but absent from the meristem.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O82318, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O82318, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-interacts (By similarity). Binds to CLE45 present in the pistil, particularly under relatively high temperature (at 30 degrees Celsius) (PubMed:23910659).

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
2473, 29 interactors

Protein interaction database and analysis system

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IntActi
O82318, 29 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT2G25790.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O82318

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati71 – 96LRR 1Sequence analysisAdd BLAST26
Repeati97 – 120LRR 2Sequence analysisAdd BLAST24
Repeati122 – 146LRR 3Sequence analysisAdd BLAST25
Repeati149 – 168LRR 4Sequence analysisAdd BLAST20
Repeati169 – 194LRR 5Sequence analysisAdd BLAST26
Repeati196 – 216LRR 6Sequence analysisAdd BLAST21
Repeati217 – 240LRR 7Sequence analysisAdd BLAST24
Repeati241 – 264LRR 8Sequence analysisAdd BLAST24
Repeati265 – 288LRR 9Sequence analysisAdd BLAST24
Repeati290 – 312LRR 10Sequence analysisAdd BLAST23
Repeati313 – 336LRR 11Sequence analysisAdd BLAST24
Repeati338 – 360LRR 12Sequence analysisAdd BLAST23
Repeati361 – 384LRR 13Sequence analysisAdd BLAST24
Repeati386 – 408LRR 14Sequence analysisAdd BLAST23
Repeati409 – 432LRR 15Sequence analysisAdd BLAST24
Repeati434 – 454LRR 16Sequence analysisAdd BLAST21
Repeati455 – 477LRR 17Sequence analysisAdd BLAST23
Repeati478 – 501LRR 18Sequence analysisAdd BLAST24
Repeati503 – 525LRR 19Sequence analysisAdd BLAST23
Repeati526 – 549LRR 20Sequence analysisAdd BLAST24
Repeati550 – 573LRR 21Sequence analysisAdd BLAST24
Repeati575 – 598LRR 22Sequence analysisAdd BLAST24
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini691 – 953Protein kinasePROSITE-ProRule annotationAdd BLAST263

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi221 – 226CLE45 peptide bindingBy similarity6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRRF, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000288_22_1_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
O82318

Identification of Orthologs from Complete Genome Data

More...
OMAi
WIDSSID

Database of Orthologous Groups

More...
OrthoDBi
826997at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O82318

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.80.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
IPR013210, LRR_N_plant-typ
IPR000719, Prot_kinase_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00560, LRR_1, 1 hit
PF13855, LRR_8, 3 hits
PF08263, LRRNT_2, 1 hit
PF00069, Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00369, LRR_TYP, 9 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF56112, SSF56112, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS50011, PROTEIN_KINASE_DOM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

O82318-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTSHHHHHP PYLITTLFFL FLNFSCLHAN ELELLLSFKS SIQDPLKHLS
60 70 80 90 100
SWSYSSTNDV CLWSGVVCNN ISRVVSLDLS GKNMSGQILT AATFRLPFLQ
110 120 130 140 150
TINLSNNNLS GPIPHDIFTT SSPSLRYLNL SNNNFSGSIP RGFLPNLYTL
160 170 180 190 200
DLSNNMFTGE IYNDIGVFSN LRVLDLGGNV LTGHVPGYLG NLSRLEFLTL
210 220 230 240 250
ASNQLTGGVP VELGKMKNLK WIYLGYNNLS GEIPYQIGGL SSLNHLDLVY
260 270 280 290 300
NNLSGPIPPS LGDLKKLEYM FLYQNKLSGQ IPPSIFSLQN LISLDFSDNS
310 320 330 340 350
LSGEIPELVA QMQSLEILHL FSNNLTGKIP EGVTSLPRLK VLQLWSNRFS
360 370 380 390 400
GGIPANLGKH NNLTVLDLST NNLTGKLPDT LCDSGHLTKL ILFSNSLDSQ
410 420 430 440 450
IPPSLGMCQS LERVRLQNNG FSGKLPRGFT KLQLVNFLDL SNNNLQGNIN
460 470 480 490 500
TWDMPQLEML DLSVNKFFGE LPDFSRSKRL KKLDLSRNKI SGVVPQGLMT
510 520 530 540 550
FPEIMDLDLS ENEITGVIPR ELSSCKNLVN LDLSHNNFTG EIPSSFAEFQ
560 570 580 590 600
VLSDLDLSCN QLSGEIPKNL GNIESLVQVN ISHNLLHGSL PFTGAFLAIN
610 620 630 640 650
ATAVEGNIDL CSENSASGLR PCKVVRKRST KSWWLIITST FAAFLAVLVS
660 670 680 690 700
GFFIVLVFQR THNVLEVKKV EQEDGTKWET QFFDSKFMKS FTVNTILSSL
710 720 730 740 750
KDQNVLVDKN GVHFVVKEVK KYDSLPEMIS DMRKLSDHKN ILKIVATCRS
760 770 780 790 800
ETVAYLIHED VEGKRLSQVL SGLSWERRRK IMKGIVEALR FLHCRCSPAV
810 820 830 840 850
VAGNLSPENI VIDVTDEPRL CLGLPGLLCM DAAYMAPETR EHKEMTSKSD
860 870 880 890 900
IYGFGILLLH LLTGKCSSSN EDIESGVNGS LVKWARYSYS NCHIDTWIDS
910 920 930 940 950
SIDTSVHQRE IVHVMNLALK CTAIDPQERP CTNNVLQALE STSSSSSSCT
960
TYLSKILSLA
Length:960
Mass (Da):106,448
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i865D523C610DD838
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA23395 differs from that shown. Reason: Frameshift.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC005395 Genomic DNA Translation: AAC42251.1
CP002685 Genomic DNA Translation: AEC07753.1
FJ708700 mRNA Translation: ACN59295.1
F20108 mRNA Translation: CAA23395.1 Frameshift.

Protein sequence database of the Protein Information Resource

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PIRi
G84652

NCBI Reference Sequences

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RefSeqi
NP_180150.1, NM_128139.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G25790.1; AT2G25790.1; AT2G25790

Database of genes from NCBI RefSeq genomes

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GeneIDi
817121

Gramene; a comparative resource for plants

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Gramenei
AT2G25790.1; AT2G25790.1; AT2G25790

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT2G25790

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005395 Genomic DNA Translation: AAC42251.1
CP002685 Genomic DNA Translation: AEC07753.1
FJ708700 mRNA Translation: ACN59295.1
F20108 mRNA Translation: CAA23395.1 Frameshift.
PIRiG84652
RefSeqiNP_180150.1, NM_128139.3

3D structure databases

SMRiO82318
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi2473, 29 interactors
IntActiO82318, 29 interactors
STRINGi3702.AT2G25790.1

Proteomic databases

PaxDbiO82318
PRIDEiO82318
ProteomicsDBi243149

Genome annotation databases

EnsemblPlantsiAT2G25790.1; AT2G25790.1; AT2G25790
GeneIDi817121
GrameneiAT2G25790.1; AT2G25790.1; AT2G25790
KEGGiath:AT2G25790

Organism-specific databases

AraportiAT2G25790
TAIRilocus:2043540, AT2G25790

Phylogenomic databases

eggNOGiENOG502QRRF, Eukaryota
HOGENOMiCLU_000288_22_1_1
InParanoidiO82318
OMAiWIDSSID
OrthoDBi826997at2759
PhylomeDBiO82318

Miscellaneous databases

Protein Ontology

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PROi
PR:O82318

Gene expression databases

ExpressionAtlasiO82318, baseline and differential
GenevisibleiO82318, AT

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR001611, Leu-rich_rpt
IPR003591, Leu-rich_rpt_typical-subtyp
IPR032675, LRR_dom_sf
IPR013210, LRR_N_plant-typ
IPR000719, Prot_kinase_dom
PfamiView protein in Pfam
PF00560, LRR_1, 1 hit
PF13855, LRR_8, 3 hits
PF08263, LRRNT_2, 1 hit
PF00069, Pkinase, 1 hit
SMARTiView protein in SMART
SM00369, LRR_TYP, 9 hits
SUPFAMiSSF56112, SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011, PROTEIN_KINASE_DOM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSKM1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O82318
Secondary accession number(s): Q42355
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 24, 2009
Last sequence update: November 1, 1998
Last modified: April 7, 2021
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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