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Entry version 121 (11 Dec 2019)
Sequence version 1 (01 Nov 1998)
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Protein

Zinc finger CCCH domain-containing protein 23

Gene

At2g25900

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri131 – 157C3H1-type 1PROSITE-ProRule annotationAdd BLAST27
Zinc fingeri165 – 189C3H1-type 2PROSITE-ProRule annotationAdd BLAST25

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger CCCH domain-containing protein 23
Short name:
AtC3H23
Alternative name(s):
Protein ATCTH
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At2g25900
ORF Names:F17H15.7
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G25900

The Arabidopsis Information Resource

More...
TAIRi
locus:2043565 AT2G25900

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003719821 – 315Zinc finger CCCH domain-containing protein 23Add BLAST315

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O82307

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O82307 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O82307 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
2483, 13 interactors

Protein interaction database and analysis system

More...
IntActi
O82307, 12 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT2G25900.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O82307

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri131 – 157C3H1-type 1PROSITE-ProRule annotationAdd BLAST27
Zinc fingeri165 – 189C3H1-type 2PROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410ITVH Eukaryota
ENOG410Y7IC LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000237601

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O82307

Identification of Orthologs from Complete Genome Data

More...
OMAi
YRTHLCK

Database of Orthologous Groups

More...
OrthoDBi
1188286at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O82307

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041367 Znf-CCCH_4
IPR000571 Znf_CCCH

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF18044 zf-CCCH_4, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00356 ZnF_C3H1, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50103 ZF_C3H1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O82307-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMIGENKNRP HPTIHIPQWD QINDPTATIS SPFSSVNLNS VNDYPHSPSP
60 70 80 90 100
YLDSFASLFR YLPSNELTND SDSSSGDESS PLTDSFSSDE FRIYEFKIRR
110 120 130 140 150
CARGRSHDWT ECPFAHPGEK ARRRDPRKFH YSGTACPEFR KGSCRRGDSC
160 170 180 190 200
EFSHGVFECW LHPSRYRTQP CKDGTSCRRR ICFFAHTTEQ LRVLPCSLDP
210 220 230 240 250
DLGFFSGLAT SPTSILVSPS FSPPSESPPL SPSTGELIAS MRKMQLNGGG
260 270 280 290 300
CSWSSPMRSA VRLPFSSSLR PIQAATWPRI REFEIEEAPA MEFVESGKEL
310
RAEMYARLSR ENSLG
Length:315
Mass (Da):35,465
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i320F0157B4C432FB
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB68046 differs from that shown. Reason: Frameshift.Curated
The sequence AAB68046 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti148D → H in AAM65505 (Ref. 5) Curated1
Sequence conflicti258R → G in AAM65505 (Ref. 5) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC005395 Genomic DNA Translation: AAC42256.1
CP002685 Genomic DNA Translation: AEC07769.1
CP002685 Genomic DNA Translation: AEC07770.1
AF370590 mRNA Translation: AAK43909.1
AF375403 mRNA Translation: AAK52987.1
AY129468 mRNA Translation: AAM91054.1
AK117272 mRNA Translation: BAC41945.1
AY087957 mRNA Translation: AAM65505.1
U81238 mRNA Translation: AAB68046.1 Sequence problems.

Protein sequence database of the Protein Information Resource

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PIRi
B84654

NCBI Reference Sequences

More...
RefSeqi
NP_001189604.1, NM_001202675.1
NP_180161.1, NM_128150.5

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G25900.1; AT2G25900.1; AT2G25900
AT2G25900.2; AT2G25900.2; AT2G25900

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
817131

Gramene; a comparative resource for plants

More...
Gramenei
AT2G25900.1; AT2G25900.1; AT2G25900
AT2G25900.2; AT2G25900.2; AT2G25900

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G25900

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005395 Genomic DNA Translation: AAC42256.1
CP002685 Genomic DNA Translation: AEC07769.1
CP002685 Genomic DNA Translation: AEC07770.1
AF370590 mRNA Translation: AAK43909.1
AF375403 mRNA Translation: AAK52987.1
AY129468 mRNA Translation: AAM91054.1
AK117272 mRNA Translation: BAC41945.1
AY087957 mRNA Translation: AAM65505.1
U81238 mRNA Translation: AAB68046.1 Sequence problems.
PIRiB84654
RefSeqiNP_001189604.1, NM_001202675.1
NP_180161.1, NM_128150.5

3D structure databases

SMRiO82307
ModBaseiSearch...

Protein-protein interaction databases

BioGridi2483, 13 interactors
IntActiO82307, 12 interactors
STRINGi3702.AT2G25900.1

Proteomic databases

PaxDbiO82307

Genome annotation databases

EnsemblPlantsiAT2G25900.1; AT2G25900.1; AT2G25900
AT2G25900.2; AT2G25900.2; AT2G25900
GeneIDi817131
GrameneiAT2G25900.1; AT2G25900.1; AT2G25900
AT2G25900.2; AT2G25900.2; AT2G25900
KEGGiath:AT2G25900

Organism-specific databases

AraportiAT2G25900
TAIRilocus:2043565 AT2G25900

Phylogenomic databases

eggNOGiENOG410ITVH Eukaryota
ENOG410Y7IC LUCA
HOGENOMiHOG000237601
InParanoidiO82307
OMAiYRTHLCK
OrthoDBi1188286at2759
PhylomeDBiO82307

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O82307

Gene expression databases

ExpressionAtlasiO82307 baseline and differential
GenevisibleiO82307 AT

Family and domain databases

InterProiView protein in InterPro
IPR041367 Znf-CCCH_4
IPR000571 Znf_CCCH
PfamiView protein in Pfam
PF18044 zf-CCCH_4, 1 hit
SMARTiView protein in SMART
SM00356 ZnF_C3H1, 2 hits
PROSITEiView protein in PROSITE
PS50103 ZF_C3H1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC3H23_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O82307
Secondary accession number(s): P93029, Q8LA97
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: November 1, 1998
Last modified: December 11, 2019
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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