Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome P450 94A1

Gene

CYP94A1

Organism
Vicia sativa (Spring vetch) (Tare)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the omega-hydroxylation of various fatty acids (FA) from 10 to 18 carbon atoms. The substrate specificity is higher for laurate > palmitate > myristate > linolenate > linoleate > oleate > caprate. May play a minor role in cutin synthesis and could be involved in plant defense.

Cofactori

hemeBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi458Iron (heme axial ligand)By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenase, Oxidoreductase
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome P450 94A1 (EC:1.14.-.-)
Alternative name(s):
P450-dependent fatty acid omega-hydroxylase
Gene namesi
Name:CYP94A1
Synonyms:VAGH111
OrganismiVicia sativa (Spring vetch) (Tare)
Taxonomic identifieri3908 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideae50 kb inversion cladeNPAAA cladeHologaleginaIRL cladeFabeaeVicia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 29HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000521921 – 514Cytochrome P450 94A1Add BLAST514

Expressioni

Inductioni

By clofibrate.

Structurei

3D structure databases

ProteinModelPortaliO81117
SMRiO81117
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK13407

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit

Sequencei

Sequence statusi: Complete.

O81117-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFQFHLEVLL PYLLPLLLLI LPTTIFFLTK PNNKVSSTST NNNIITLPKS
60 70 80 90 100
YPLIGSYLSF RKNLHRRIQW LSDIVQISPS ATFQLDGTLG KRQIITGNPS
110 120 130 140 150
TVQHILKNQF SNYQKGTTFT NTLSDFLGTG IFNTNGPNWK FQRQVASHEF
160 170 180 190 200
NTKSIRNFVE HIVDTELTNR LIPILTSSTQ TNNILDFQDI LQRFTFDNIC
210 220 230 240 250
NIAFGYDPEY LTPSTNRSKF AEAYEDATEI SSKRFRLPLP IIWKIKKYFN
260 270 280 290 300
IGSEKRLKEA VTEVRSFAKK LVREKKRELE EKSSLETEDM LSRFLSSGHS
310 320 330 340 350
DEDFVADIVI SFILAGKDTT SAALTWFFWL LWKNPRVEEE IVNELSKKSE
360 370 380 390 400
LMVYDEVKEM VYTHAALSES MRLYPPVPMD SKEAVNDDVL PDGWVVKKGT
410 420 430 440 450
IVTYHVYAMG RMKSLWGDDW AEFRPERWLE KDEVNGKWVF VGRDSYSYPV
460 470 480 490 500
FQAGPRVCLG KEMAFMQMKR IVAGIVGKFK VVPEAHLAQE PGFISFLSSQ
510
MEGGFPVTIQ KRDS
Length:514
Mass (Da):59,111
Last modified:May 1, 1999 - v2
Checksum:i3D9361380D6C3B0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030260 mRNA Translation: AAD10204.1
PIRiT08014

Genome annotation databases

KEGGiag:AAD10204

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030260 mRNA Translation: AAD10204.1
PIRiT08014

3D structure databases

ProteinModelPortaliO81117
SMRiO81117
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGiag:AAD10204

Phylogenomic databases

KOiK13407

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiC94A1_VICSA
AccessioniPrimary (citable) accession number: O81117
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: May 1, 1999
Last modified: September 12, 2018
This is version 81 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again