UniProtKB - O81108 (ACA2_ARATH)

BLAST

>sp|O81108|ACA2_ARATH Calcium-transporting ATPase 2, plasma membrane-type OS=Arabidopsis thaliana OX=3702 GN=ACA2 PE=1 SV=1
MESYLNENFDVKAKHSSEEVLEKWRNLCGVVKNPKRRFRFTANLSKRYEAAAMRRTNQEK
LRIAVLVSKAAFQFISGVSPSDYTVPEDVKAAGFEICADELGSIVESHDVKKLKFHGGVD
GLAGKLKASPTDGLSTEAAQLSQRQELFGINKFAESEMRGFWVFVWEALQDMTLMILGVC
AFVSLIVGIATEGWPKGSHDGLGIAASILLVVFVTATSDYRQSLQFRDLDKEKKKITVQV
TRNGFRQKLSIYDLLPGDIVHLAIGDQVPADGLFLSGFSVVIDESSLTGESEPVMVNAQN
PFLMSGTKVQDGSCKMMITTVGMRTQWGKLMATLTEGGDDETPLQVKLNGVATIIGKIGL
FFAVVTFAVLVQGMFMRKLSTGTHWVWSGDEALELLEYFAIAVTIVVVAVPEGLPLAVTL
SLAFAMKKMMNDKALVRHLAACETMGSATTICSDKTGTLTTNHMTVVKSCICMNVQDVAN
KGSSLQSEIPESAVKLLIQSIFNNTGGEVVVNKHGKTELLGTPTETAILELGLSLGGKFQ
EERKSYKVIKVEPFNSTKKRMGVVIELPEGGRMRAHTKGASEIVLAACDKVVNSSGEVVP
LDEESIKYLNVTINEFANEALRTLCLAYMDIEGGFSPDDAIPASGFTCVGIVGIKDPVRP
GVKESVELCRRAGITVRMVTGDNINTAKAIARECGILTDDGIAIEGPVFREKNQEELLEL
IPKIQVMARSSPMDKHTLVKQLRTTFDEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVA
KESADVIILDDNFSTIVTVAKWGRSVYINIQKFVQFQLTVNVVALVVNFSSACLTGSAPL
TAVQLLWVNMIMDTLGALALATEPPNDELMKRLPVGRRGNFITNAMWRNILGQAVYQFIV
IWILQAKGKAMFGLDGPDSTLMLNTLIFNCFVFCQVFNEISSREMEEIDVFKGILDNYVF
VVVIGATVFFQIIIIEFLGTFASTTPLTITQWIFSIFIGFLGMPIAAGLKTIPV

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History
Entry version 169 (07 Nov 2018)
Sequence version 1 (01 Nov 1998)
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Protein

Calcium-transporting ATPase 2, plasma membrane-type

Gene

ACA2

Organism

Arabidopsis thaliana (Mouse-ear cress)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the endoplasmic reticulum.

Catalytic activityⁱ

ATP + H₂O + Ca²⁺(Side 1) = ADP + phosphate + Ca²⁺(Side 2).

Activity regulationⁱ

Activated by calmodulin.

Sites

Feature key	Position(s)	DescriptionActions	Length
Active siteⁱ	454	4-aspartylphosphate intermediateBy similarity	1
Metal bindingⁱ	755	MagnesiumBy similarity	1
Metal bindingⁱ	759	MagnesiumBy similarity	1

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
calcium ion transmembrane transporter activity
Source: TAIR
Inferred from direct assayⁱ
- 9422775
calcium-transporting ATPase activity
Source: TAIR
Inferred from direct assayⁱ
- 10631259
calmodulin binding
Source: TAIR
Inferred from direct assayⁱ
- 9422775
metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

calcium ion transmembrane transport
Source: TAIR
Inferred from direct assayⁱ
- 10823962

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Calmodulin-binding, Hydrolase
Biological process	Calcium transport, Ion transport, Transport
Ligand	ATP-binding, Calcium, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCycⁱ	ARA:AT4G37640-MONOMER MetaCyc:MONOMER-14659
Reactomeⁱ	R-ATH-418359 Reduction of cytosolic Ca++ levels R-ATH-5578775 Ion homeostasis R-ATH-936837 Ion transport by P-type ATPases

Protein family/group databases

TCDBⁱ	3.A.3.2.12 the p-type atpase (p-atpase) superfamily

TCDBⁱ

3.A.3.2.12 the p-type atpase (p-atpase) superfamily

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Calcium-transporting ATPase 2, plasma membrane-type (EC:3.6.3.8) Alternative name(s): Ca(2+)-ATPase isoform 2
Gene namesⁱ	Name:ACA2 Ordered Locus Names:At4g37640 ORF Names:F19F18.130
Organismⁱ	Arabidopsis thaliana (Mouse-ear cress)
Taxonomic identifierⁱ	3702 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
Proteomesⁱ	UP000006548 Componentⁱ: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal More...Araportⁱ	AT4G37640
TAIRⁱ	locus:2120096 AT4G37640

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 160	CytoplasmicSequence analysisAdd BLAST	160
Transmembraneⁱ	161 – 181	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	182 – 199	LumenalSequence analysisAdd BLAST	18
Transmembraneⁱ	200 – 220	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	221 – 348	CytoplasmicSequence analysisAdd BLAST	128
Transmembraneⁱ	349 – 368	HelicalSequence analysisAdd BLAST	20
Topological domainⁱ	369 – 398	LumenalSequence analysisAdd BLAST	30
Transmembraneⁱ	399 – 416	HelicalSequence analysisAdd BLAST	18
Topological domainⁱ	417 – 810	CytoplasmicSequence analysisAdd BLAST	394
Transmembraneⁱ	811 – 829	HelicalSequence analysisAdd BLAST	19
Topological domainⁱ	830 – 840	LumenalSequence analysisAdd BLAST	11
Transmembraneⁱ	841 – 861	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	862 – 881	CytoplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	882 – 904	HelicalSequence analysisAdd BLAST	23
Topological domainⁱ	905 – 916	LumenalSequence analysisAdd BLAST	12
Transmembraneⁱ	917 – 938	HelicalSequence analysisAdd BLAST	22
Topological domainⁱ	939 – 956	CytoplasmicSequence analysisAdd BLAST	18
Transmembraneⁱ	957 – 978	HelicalSequence analysisAdd BLAST	22
Topological domainⁱ	979 – 988	LumenalSequence analysis	10
Transmembraneⁱ	989 – 1010	HelicalSequence analysisAdd BLAST	22
Topological domainⁱ	1011 – 1014	CytoplasmicSequence analysis	4

Keywords - Cellular componentⁱ

Endoplasmic reticulum, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000046411	1 – 1014	Calcium-transporting ATPase 2, plasma membrane-typeAdd BLAST		1014

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	1	N-acetylmethionineCombined sources		1
Modified residueⁱ	45	Phosphoserine; by CPK11 Publication		1

Keywords - PTMⁱ

Acetylation, Phosphoprotein

Proteomic databases

PaxDbⁱ	O81108
PRIDEⁱ	O81108

PTM databases

iPTMnetⁱ	O81108

iPTMnetⁱ

O81108

Expressionⁱ

Gene expression databases

ExpressionAtlasⁱ	O81108 baseline and differential
Genevisibleⁱ	O81108 AT

Interactionⁱ

GO - Molecular functionⁱ

calmodulin binding
Source: TAIR
Inferred from direct assayⁱ
- 9422775

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	15199, 6 interactors
IntActⁱ	O81108, 2 interactors
STRINGⁱ	3702.AT4G37640.1

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Helixⁱ	22 – 31	Combined sources		10
Turnⁱ	34 – 36	Combined sources		3

Show more details

3D structure databases

ProteinModelPortalⁱ	O81108
SMRⁱ	O81108
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	20 – 31	Interaction with calmodulinAdd BLAST		12

Domainⁱ

The N-terminus contains an autoinhibitory calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion.

Sequence similaritiesⁱ

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily. [View classification]Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG0204 Eukaryota ENOG410XNNC LUCA
HOGENOMⁱ	HOG000265623
InParanoidⁱ	O81108
KEGG Orthology (KO) More...KOⁱ	K01537
OMAⁱ	TQWIFSI
Database of Orthologous Groups More...OrthoDBⁱ	EOG093600UZ
PhylomeDBⁱ	O81108

Family and domain databases

Gene3Dⁱ	3.40.1110.10, 1 hit 3.40.50.1000, 1 hit
InterProⁱ	View protein in InterPro IPR006068 ATPase_P-typ_cation-transptr_C IPR004014 ATPase_P-typ_cation-transptr_N IPR023299 ATPase_P-typ_cyto_dom_N IPR018303 ATPase_P-typ_P_site IPR023298 ATPase_P-typ_TM_dom_sf IPR008250 ATPase_P-typ_transduc_dom_A_sf IPR024750 Ca_ATPase_N_dom IPR036412 HAD-like_sf IPR023214 HAD_sf IPR006408 P-type_ATPase_IIB IPR001757 P_typ_ATPase
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12515 CaATP_NAI, 1 hit PF00689 Cation_ATPase_C, 1 hit PF00690 Cation_ATPase_N, 1 hit
PRINTSⁱ	PR00120 HATPASE
SMARTⁱ	View protein in SMART SM00831 Cation_ATPase_N, 1 hit
SUPFAMⁱ	SSF56784 SSF56784, 1 hit SSF81653 SSF81653, 1 hit SSF81660 SSF81660, 1 hit SSF81665 SSF81665, 1 hit
TIGRFAMsⁱ	TIGR01517 ATPase-IIB_Ca, 1 hit TIGR01494 ATPase_P-type, 3 hits
PROSITEⁱ	View protein in PROSITE PS00154 ATPASE_E1_E2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

O81108-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MESYLNENFD VKAKHSSEEV LEKWRNLCGV VKNPKRRFRF TANLSKRYEA 
        60         70         80         90        100
AAMRRTNQEK LRIAVLVSKA AFQFISGVSP SDYTVPEDVK AAGFEICADE 
       110        120        130        140        150
LGSIVESHDV KKLKFHGGVD GLAGKLKASP TDGLSTEAAQ LSQRQELFGI 
       160        170        180        190        200
NKFAESEMRG FWVFVWEALQ DMTLMILGVC AFVSLIVGIA TEGWPKGSHD 
       210        220        230        240        250
GLGIAASILL VVFVTATSDY RQSLQFRDLD KEKKKITVQV TRNGFRQKLS 
       260        270        280        290        300
IYDLLPGDIV HLAIGDQVPA DGLFLSGFSV VIDESSLTGE SEPVMVNAQN 
       310        320        330        340        350
PFLMSGTKVQ DGSCKMMITT VGMRTQWGKL MATLTEGGDD ETPLQVKLNG 
       360        370        380        390        400
VATIIGKIGL FFAVVTFAVL VQGMFMRKLS TGTHWVWSGD EALELLEYFA 
       410        420        430        440        450
IAVTIVVVAV PEGLPLAVTL SLAFAMKKMM NDKALVRHLA ACETMGSATT 
       460        470        480        490        500
ICSDKTGTLT TNHMTVVKSC ICMNVQDVAN KGSSLQSEIP ESAVKLLIQS 
       510        520        530        540        550
IFNNTGGEVV VNKHGKTELL GTPTETAILE LGLSLGGKFQ EERKSYKVIK 
       560        570        580        590        600
VEPFNSTKKR MGVVIELPEG GRMRAHTKGA SEIVLAACDK VVNSSGEVVP 
       610        620        630        640        650
LDEESIKYLN VTINEFANEA LRTLCLAYMD IEGGFSPDDA IPASGFTCVG 
       660        670        680        690        700
IVGIKDPVRP GVKESVELCR RAGITVRMVT GDNINTAKAI ARECGILTDD 
       710        720        730        740        750
GIAIEGPVFR EKNQEELLEL IPKIQVMARS SPMDKHTLVK QLRTTFDEVV 
       760        770        780        790        800
AVTGDGTNDA PALHEADIGL AMGIAGTEVA KESADVIILD DNFSTIVTVA 
       810        820        830        840        850
KWGRSVYINI QKFVQFQLTV NVVALVVNFS SACLTGSAPL TAVQLLWVNM 
       860        870        880        890        900
IMDTLGALAL ATEPPNDELM KRLPVGRRGN FITNAMWRNI LGQAVYQFIV 
       910        920        930        940        950
IWILQAKGKA MFGLDGPDST LMLNTLIFNC FVFCQVFNEI SSREMEEIDV 
       960        970        980        990       1000
FKGILDNYVF VVVIGATVFF QIIIIEFLGT FASTTPLTIT QWIFSIFIGF 
      1010 
LGMPIAAGLK TIPV

Length:1,014

Mass (Da):110,439

Last modified:November 1, 1998 - v1

Checksum:ⁱ996DEFD26AFE9F03

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF025842 mRNA Translation: AAC26997.1 AL035605 Genomic DNA Translation: CAB38303.1 AL161591 Genomic DNA Translation: CAB80429.1 CP002687 Genomic DNA Translation: AEE86819.1 AY062484 mRNA Translation: AAL32562.1
PIRⁱ	T04721
NCBI Reference Sequences More...RefSeqⁱ	NP_195479.1, NM_119927.3
UniGeneⁱ	At.24252

Genome annotation databases

EnsemblPlantsⁱ	AT4G37640.1; AT4G37640.1; AT4G37640
GeneIDⁱ	829918
Grameneⁱ	AT4G37640.1; AT4G37640.1; AT4G37640
KEGGⁱ	ath:AT4G37640

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O81108	ACA2		ARATH		1014	UniRef100_O81108
Calcium-transporting ATPase		ARATH		1014
Plasma membrane-type calcium ATPase		ARATH		288

Protein	Similar proteins		Species	Score	Length	Source
O81108	Putative calcium-transporting ATPase 7, plasma membrane-type		ARATH		1015	UniRef90_O81108
Putative calcium-transporting ATPase 7, plasma membrane-type (Fragment)		NOCCA		86
Calcium-transporting ATPase		BRANA		1019
Calcium-transporting ATPase		Capsella rubella		1015
Calcium-transporting ATPase		ARALL		1015
+41

Protein	Similar proteins		Species	Score	Length	Source
O81108	Putative calcium-transporting ATPase 7, plasma membrane-type		ARATH		1015	UniRef50_O81108
Putative calcium-transporting ATPase 7, plasma membrane-type (Fragment)		NOCCA		86
Calcium-transporting ATPase		BRANA		1019
Calcium-transporting ATPase		ARALL		1015
Calcium-transporting ATPase		Capsella rubella		1015
+69

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF025842 mRNA Translation: AAC26997.1 AL035605 Genomic DNA Translation: CAB38303.1 AL161591 Genomic DNA Translation: CAB80429.1 CP002687 Genomic DNA Translation: AEE86819.1 AY062484 mRNA Translation: AAL32562.1
PIRⁱ	T04721
RefSeqⁱ	NP_195479.1, NM_119927.3
UniGeneⁱ	At.24252

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2M7E	NMR	-	A	20-45	[»]
ProteinModelPortalⁱ	O81108
SMRⁱ	O81108
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	15199, 6 interactors
IntActⁱ	O81108, 2 interactors
STRINGⁱ	3702.AT4G37640.1

Protein family/group databases

TCDBⁱ	3.A.3.2.12 the p-type atpase (p-atpase) superfamily

TCDBⁱ

3.A.3.2.12 the p-type atpase (p-atpase) superfamily

PTM databases

iPTMnetⁱ	O81108

iPTMnetⁱ

O81108

Proteomic databases

PaxDbⁱ	O81108
PRIDEⁱ	O81108

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblPlantsⁱ	AT4G37640.1; AT4G37640.1; AT4G37640
GeneIDⁱ	829918
Grameneⁱ	AT4G37640.1; AT4G37640.1; AT4G37640
KEGGⁱ	ath:AT4G37640

Organism-specific databases

Araportⁱ	AT4G37640
TAIRⁱ	locus:2120096 AT4G37640

Phylogenomic databases

eggNOGⁱ	KOG0204 Eukaryota ENOG410XNNC LUCA
HOGENOMⁱ	HOG000265623
InParanoidⁱ	O81108
KOⁱ	K01537
OMAⁱ	TQWIFSI
OrthoDBⁱ	EOG093600UZ
PhylomeDBⁱ	O81108

Enzyme and pathway databases

BioCycⁱ	ARA:AT4G37640-MONOMER MetaCyc:MONOMER-14659
Reactomeⁱ	R-ATH-418359 Reduction of cytosolic Ca++ levels R-ATH-5578775 Ion homeostasis R-ATH-936837 Ion transport by P-type ATPases

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:O81108

PROⁱ

PR:O81108

Gene expression databases

ExpressionAtlasⁱ	O81108 baseline and differential
Genevisibleⁱ	O81108 AT

Family and domain databases

Gene3Dⁱ	3.40.1110.10, 1 hit 3.40.50.1000, 1 hit
InterProⁱ	View protein in InterPro IPR006068 ATPase_P-typ_cation-transptr_C IPR004014 ATPase_P-typ_cation-transptr_N IPR023299 ATPase_P-typ_cyto_dom_N IPR018303 ATPase_P-typ_P_site IPR023298 ATPase_P-typ_TM_dom_sf IPR008250 ATPase_P-typ_transduc_dom_A_sf IPR024750 Ca_ATPase_N_dom IPR036412 HAD-like_sf IPR023214 HAD_sf IPR006408 P-type_ATPase_IIB IPR001757 P_typ_ATPase
Pfamⁱ	View protein in Pfam PF12515 CaATP_NAI, 1 hit PF00689 Cation_ATPase_C, 1 hit PF00690 Cation_ATPase_N, 1 hit
PRINTSⁱ	PR00120 HATPASE
SMARTⁱ	View protein in SMART SM00831 Cation_ATPase_N, 1 hit
SUPFAMⁱ	SSF56784 SSF56784, 1 hit SSF81653 SSF81653, 1 hit SSF81660 SSF81660, 1 hit SSF81665 SSF81665, 1 hit
TIGRFAMsⁱ	TIGR01517 ATPase-IIB_Ca, 1 hit TIGR01494 ATPase_P-type, 3 hits
PROSITEⁱ	View protein in PROSITE PS00154 ATPASE_E1_E2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ACA2_ARATH
Accessionⁱ	O81108Primary (citable) accession number: O81108
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
	Last sequence update:	November 1, 1998
	Last modified:	November 7, 2018
	This is version 169 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Plant Protein Annotation Program

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Supporting data

UniProtKB - O81108 (ACA2_ARATH)

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Calcium-transporting ATPase 2, plasma membrane-type

ACA2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Endoplasmic reticulum

Endoplasmic reticulum

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ