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Protein

U-box domain-containing protein 19

Gene

PUB19

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Functions as an E3 ubiquitin ligase.By similarity

Catalytic activityi

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine.

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

  • regulation of seed germination Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway

Enzyme and pathway databases

UniPathwayi
UPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
U-box domain-containing protein 19 (EC:2.3.2.27)
Alternative name(s):
Plant U-box protein 19
RING-type E3 ubiquitin transferase PUB19Curated
Gene namesi
Name:PUB19
Ordered Locus Names:At1g60190
ORF Names:T13D8.8
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G60190
TAIRilocus:2195563 AT1G60190

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003221631 – 686U-box domain-containing protein 19Add BLAST686

Proteomic databases

PaxDbiO80742
PRIDEiO80742

PTM databases

iPTMnetiO80742

Expressioni

Gene expression databases

ExpressionAtlasiO80742 baseline and differential
GenevisibleiO80742 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G60190.1

Structurei

3D structure databases

ProteinModelPortaliO80742
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini277 – 351U-boxAdd BLAST75
Repeati406 – 445ARM 1Add BLAST40
Repeati448 – 489ARM 2Add BLAST42
Repeati491 – 533ARM 3Add BLAST43
Repeati536 – 577ARM 4Add BLAST42
Repeati579 – 620ARM 5Add BLAST42

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410ITM9 Eukaryota
ENOG410YCUS LUCA
HOGENOMiHOG000238412
InParanoidiO80742
OMAiVRKWRDC
OrthoDBiEOG093604SG
PhylomeDBiO80742

Family and domain databases

Gene3Di1.25.10.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR003613 Ubox_domain
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00514 Arm, 1 hit
PF04564 U-box, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 3 hits
SM00504 Ubox, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 2 hits
PS51698 U_BOX, 1 hit

Sequencei

Sequence statusi: Complete.

O80742-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIHTPTGSSR RILTFPAVNP CESISLTTLV DSLLQLAGEI LSFKPKHFST
60 70 80 90 100
NKRSVKETLR HVQTLVIFFE ELRIQIRVGS IPAGRSVILS LSELHVIFQK
110 120 130 140 150
LKFLLDDCTR DGAKLYMLMN SGQVSAHFRD LTRSISTSLD TFPVRSVDLP
160 170 180 190 200
GEVNELIYLV MRQTRKSEAR PDRDDKRAID SVYWFFNLFE NRINPNSDEI
210 220 230 240 250
LRVLDHIGVR KWRDCVKEID FLREEISVGK KSNIEIELLS NLMGFICYCR
260 270 280 290 300
CVILRGIDVD DEEKDKEEDD LMMVRSLNVD DLRCPISLEI MSDPVVLESG
310 320 330 340 350
HTYDRSSITK WFASGNITCP KTGKTLVSTV LVDNFSVKQV IQSYSKQNGV
360 370 380 390 400
VMGQKGKKKV DVAESLAAEE AGKLTAEFLA GELIKGDEEE MVKALVEIRI
410 420 430 440 450
LTKTSTFYRS CLVEAGVVES LMKILRSDDP RIQENAMAGI MNLSKDIAGK
460 470 480 490 500
TRIVGEDGGG LRLIVEVLND GARRESRQYA AAALFYLSSL GDYSRLIGEI
510 520 530 540 550
SDAIPGLVRI VKSCDYGDSA KRNALIAIRS LLMNQPDNHW RILAAGIVPV
560 570 580 590 600
LLDLVKSEEI SDGVTADSMA ILAKMAEYPD GMISVLRRGG LKLAVKILGS
610 620 630 640 650
SEVSPATKQH CVALLLNLCH NGGSDVVGSL AKNPSIMGSL YTASSNGELG
660 670 680
GGKKASALIK MIHEFQERKT GPGEPVLERE RFVHAW
Length:686
Mass (Da):76,014
Last modified:November 1, 1998 - v1
Checksum:i59ED9D54AA062512
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004473 Genomic DNA Translation: AAC24052.1
CP002684 Genomic DNA Translation: AEE33665.1
PIRiT02271
RefSeqiNP_176225.1, NM_104709.3
UniGeneiAt.66059

Genome annotation databases

EnsemblPlantsiAT1G60190.1; AT1G60190.1; AT1G60190
GeneIDi842314
GrameneiAT1G60190.1; AT1G60190.1; AT1G60190
KEGGiath:AT1G60190

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004473 Genomic DNA Translation: AAC24052.1
CP002684 Genomic DNA Translation: AEE33665.1
PIRiT02271
RefSeqiNP_176225.1, NM_104709.3
UniGeneiAt.66059

3D structure databases

ProteinModelPortaliO80742
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G60190.1

PTM databases

iPTMnetiO80742

Proteomic databases

PaxDbiO80742
PRIDEiO80742

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G60190.1; AT1G60190.1; AT1G60190
GeneIDi842314
GrameneiAT1G60190.1; AT1G60190.1; AT1G60190
KEGGiath:AT1G60190

Organism-specific databases

AraportiAT1G60190
TAIRilocus:2195563 AT1G60190

Phylogenomic databases

eggNOGiENOG410ITM9 Eukaryota
ENOG410YCUS LUCA
HOGENOMiHOG000238412
InParanoidiO80742
OMAiVRKWRDC
OrthoDBiEOG093604SG
PhylomeDBiO80742

Enzyme and pathway databases

UniPathwayi
UPA00143

Miscellaneous databases

PROiPR:O80742

Gene expression databases

ExpressionAtlasiO80742 baseline and differential
GenevisibleiO80742 AT

Family and domain databases

Gene3Di1.25.10.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR003613 Ubox_domain
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00514 Arm, 1 hit
PF04564 U-box, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 3 hits
SM00504 Ubox, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 2 hits
PS51698 U_BOX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPUB19_ARATH
AccessioniPrimary (citable) accession number: O80742
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 1, 1998
Last modified: November 7, 2018
This is version 132 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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Main funding by: National Institutes of Health

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