Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 146 (16 Oct 2019)
Sequence version 1 (01 Nov 1998)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

ABC transporter B family member 4

Gene

ABCB4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Auxin influx transporter that mediates the transport of auxin in roots. Contributes to the basipetal transport in hypocotyls and root tips by establishing an auxin uptake sink in the root cap. Confers sensitivity to 1-N-naphthylphthalamic acid (NPA). Regulates the root elongation, the initiation of lateral roots and the development of root hairs. Can transport IAA, indole-3-propionic acid, NPA syringic acid, vanillic acid and some auxin metabolites, but not 2,4-D and 1-naphthaleneacetic acid.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi419 – 426ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi1077 – 1084ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAuxin signaling pathway, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT2G47000-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.201.7 the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ABC transporter B family member 4
Short name:
ABC transporter ABCB.4
Short name:
AtABCB4
Alternative name(s):
Multidrug resistance protein 4
P-glycoprotein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCB4
Synonyms:MDR4, PGP4
Ordered Locus Names:At2g47000
ORF Names:F14M4.17
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G47000

The Arabidopsis Information Resource

More...
TAIRi
locus:2041434 AT2G47000

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei60 – 80HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei109 – 129HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei186 – 206HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei208 – 228HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei288 – 308HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei317 – 337HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei721 – 741HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei764 – 784HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei850 – 870HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei871 – 891HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei942 – 962HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei976 – 996HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002279151 – 1286ABC transporter B family member 4Add BLAST1286

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi94N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi97N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi500N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi571N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi666N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei671PhosphoserineCombined sources1
Glycosylationi816N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi846N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1131N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1230N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation level varies significantly during early response to bacterial elicitor.

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O80725

PRoteomics IDEntifications database

More...
PRIDEi
O80725

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O80725

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O80725

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mostly expressed in roots, especially in the root elongation zone and lateral roots. In mature portion of the root, expressed in the epidermis and cortex. In the root elongation zone, confined to epidermis. In root tips, present in the root cap, S3 columella and epidermal cells.2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Highly expressed at early stages of root development.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By auxin, and cytokinins such as kinetin. Repressed by abscisic acid and cold treatment.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O80725 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O80725 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with 1-naphthylphthalamic acid (NPA).

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4649, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT2G47000.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O80725

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini63 – 349ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST287
Domaini384 – 620ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini720 – 1007ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST288
Domaini1042 – 1279ABC transporter 2PROSITE-ProRule annotationAdd BLAST238

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0055 Eukaryota
COG1132 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O80725

KEGG Orthology (KO)

More...
KOi
K05658

Identification of Orthologs from Complete Genome Data

More...
OMAi
SGQEKEN

Database of Orthologous Groups

More...
OrthoDBi
186078at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O80725

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1560.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter

The PANTHER Classification System

More...
PANTHERi
PTHR24221 PTHR24221, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

O80725-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASESGLNGD PNILEEVSET KRDKEEEEEV KKTEKKDEEH EKTKTVPFYK
60 70 80 90 100
LFAFADSFDF LLMILGTLGS IGNGLGFPLM TLLFGDLIDA FGENQTNTTD
110 120 130 140 150
KVSKVALKFV WLGIGTFAAA FLQLSGWMIS GERQAARIRS LYLKTILRQD
160 170 180 190 200
IAFFDIDTNT GEVVGRMSGD TVLIQDAMGE KVGKAIQLLA TFVGGFVIAF
210 220 230 240 250
VRGWLLTLVM LSSIPLLVMA GALLAIVIAK TASRGQTAYA KAATVVEQTI
260 270 280 290 300
GSIRTVASFT GEKQAISNYN KHLVTAYKAG VIEGGSTGLG LGTLFLVVFC
310 320 330 340 350
SYALAVWYGG KLILDKGYTG GQVLNIIIAV LTGSMSLGQT SPCLSAFAAG
360 370 380 390 400
QAAAYKMFET IERRPNIDSY STNGKVLDDI KGDIELKDVY FTYPARPDEQ
410 420 430 440 450
IFRGFSLFIS SGTTVALVGQ SGSGKSTVVS LIERFYDPQA GDVLIDGINL
460 470 480 490 500
KEFQLKWIRS KIGLVSQEPV LFTASIKDNI AYGKEDATTE EIKAAAELAN
510 520 530 540 550
ASKFVDKLPQ GLDTMVGEHG TQLSGGQKQR IAVARAILKD PRILLLDEAT
560 570 580 590 600
SALDAESERV VQEALDRIMV NRTTVVVAHR LSTVRNADMI AVIHQGKIVE
610 620 630 640 650
KGSHTELLKD PEGAYSQLIR LQEEKKSDEN AAEEQKMSSI ESFKQSSLRK
660 670 680 690 700
SSLGRSLSKG GSSRGNSSRH SFNMFGFPAG IDGNVVQDQE EDDTTQPKTE
710 720 730 740 750
PKKVSIFRIA ALNKPEIPVL ILGSISAAAN GVILPIFGIL ISSVIKAFFQ
760 770 780 790 800
PPKKLKEDTS FWAIIFMVLG FASIIAYPAQ TFFFAIAGCK LVQRIRSMCF
810 820 830 840 850
EKVVHMEVGW FDEPENSSGT IGARLSADAA TIRGLVGDSL AQTVQNLSSI
860 870 880 890 900
LAGLIIAFLA CWQLAFVVLA MLPLIALNGF LYMKFMKGFS ADAKKMYGEA
910 920 930 940 950
SQVANDAVGS IRTVASFCAE DKVMNMYSKK CEGPMKNGIR QGIVSGIGFG
960 970 980 990 1000
FSFFVLFSSY AASFYVGARL VDDGKTTFDS VFRVFFALTM AAMAISQSSS
1010 1020 1030 1040 1050
LSPDSSKADV AAASIFAIMD RESKIDPSVE SGRVLDNVKG DIELRHVSFK
1060 1070 1080 1090 1100
YPARPDVQIF QDLCLSIRAG KTVALVGESG SGKSTVIALL QRFYDPDSGE
1110 1120 1130 1140 1150
ITLDGVEIKS LRLKWLRQQT GLVSQEPILF NETIRANIAY GKGGDASESE
1160 1170 1180 1190 1200
IVSSAELSNA HGFISGLQQG YDTMVGERGI QLSGGQKQRV AIARAIVKDP
1210 1220 1230 1240 1250
KVLLLDEATS ALDAESERVV QDALDRVMVN RTTIVVAHRL STIKNADVIA
1260 1270 1280
VVKNGVIVEK GKHDTLINIK DGVYASLVQL HLTAAS
Length:1,286
Mass (Da):139,028
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i97D2A8AFEBA698E6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8AYF4A0A1P8AYF4_ARATH
ATP binding cassette subfamily B4
ABCB4 ARABIDOPSIS P-GLYCOPROTEIN 4, AtABCB4, ATP-binding cassette B4, ATPGP4, MDR4
1,113Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8AYG2A0A1P8AYG2_ARATH
ATP binding cassette subfamily B4
ABCB4 ARABIDOPSIS P-GLYCOPROTEIN 4, AtABCB4, ATP-binding cassette B4, ATPGP4, MDR4
1,002Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8AYL3A0A1P8AYL3_ARATH
ATP binding cassette subfamily B4
ABCB4 ARABIDOPSIS P-GLYCOPROTEIN 4, AtABCB4, ATP-binding cassette B4, ATPGP4, MDR4
1,179Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC004411 Genomic DNA Translation: AAC34225.1
CP002685 Genomic DNA Translation: AEC10785.1
CP002685 Genomic DNA Translation: ANM61709.1
CP002685 Genomic DNA Translation: ANM61712.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T02187

NCBI Reference Sequences

More...
RefSeqi
NP_001323911.1, NM_001337237.1
NP_001323914.1, NM_001337236.1
NP_182223.1, NM_130268.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G47000.1; AT2G47000.1; AT2G47000
AT2G47000.5; AT2G47000.5; AT2G47000
AT2G47000.6; AT2G47000.6; AT2G47000

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
819314

Gramene; a comparative resource for plants

More...
Gramenei
AT2G47000.1; AT2G47000.1; AT2G47000
AT2G47000.5; AT2G47000.5; AT2G47000
AT2G47000.6; AT2G47000.6; AT2G47000

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G47000

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004411 Genomic DNA Translation: AAC34225.1
CP002685 Genomic DNA Translation: AEC10785.1
CP002685 Genomic DNA Translation: ANM61709.1
CP002685 Genomic DNA Translation: ANM61712.1
PIRiT02187
RefSeqiNP_001323911.1, NM_001337237.1
NP_001323914.1, NM_001337236.1
NP_182223.1, NM_130268.4

3D structure databases

SMRiO80725
ModBaseiSearch...

Protein-protein interaction databases

BioGridi4649, 1 interactor
STRINGi3702.AT2G47000.1

Protein family/group databases

TCDBi3.A.1.201.7 the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiO80725
SwissPalmiO80725

Proteomic databases

PaxDbiO80725
PRIDEiO80725

Genome annotation databases

EnsemblPlantsiAT2G47000.1; AT2G47000.1; AT2G47000
AT2G47000.5; AT2G47000.5; AT2G47000
AT2G47000.6; AT2G47000.6; AT2G47000
GeneIDi819314
GrameneiAT2G47000.1; AT2G47000.1; AT2G47000
AT2G47000.5; AT2G47000.5; AT2G47000
AT2G47000.6; AT2G47000.6; AT2G47000
KEGGiath:AT2G47000

Organism-specific databases

AraportiAT2G47000
TAIRilocus:2041434 AT2G47000

Phylogenomic databases

eggNOGiKOG0055 Eukaryota
COG1132 LUCA
InParanoidiO80725
KOiK05658
OMAiSGQEKEN
OrthoDBi186078at2759
PhylomeDBiO80725

Enzyme and pathway databases

BioCyciARA:AT2G47000-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O80725

Gene expression databases

ExpressionAtlasiO80725 baseline and differential
GenevisibleiO80725 AT

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter
PANTHERiPTHR24221 PTHR24221, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAB4B_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O80725
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 1, 1998
Last modified: October 16, 2019
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again