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Entry version 150 (07 Oct 2020)
Sequence version 1 (01 Nov 1998)
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Protein

Endo-1,4-beta-xylanase 2

Gene

XYN2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to and hydrolyzes insoluble and soluble xylan substrates.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.PROSITE-ProRule annotation EC:3.2.1.8

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei840Proton donorPROSITE-ProRule annotation1
Active sitei941NucleophilePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • endo-1,4-beta-xylanase activity Source: TAIR

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00114

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM22, Carbohydrate-Binding Module Family 22
GH10, Glycoside Hydrolase Family 10

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Endo-1,4-beta-xylanase 21 Publication (EC:3.2.1.8PROSITE-ProRule annotation)
Short name:
AtXyn21 Publication
Short name:
Xylan endohydrolase 21 Publication
Short name:
Xylanase 21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:XYN21 Publication
Ordered Locus Names:At1g10050Imported
ORF Names:T27I1.7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G10050

The Arabidopsis Information Resource

More...
TAIRi
locus:2201911, AT1G10050

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004451961 – 1063Endo-1,4-beta-xylanase 2Add BLAST1063

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O80596

PRoteomics IDEntifications database

More...
PRIDEi
O80596

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
242379

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O80596

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O80596, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 146CBM-cenC 1Sequence analysisAdd BLAST142
Domaini183 – 313CBM-cenC 2Sequence analysisAdd BLAST131
Domaini348 – 482CBM-cenC 3Sequence analysisAdd BLAST135
Domaini517 – 662CBM-cenC 4Sequence analysisAdd BLAST146
Domaini711 – 1006GH10PROSITE-ProRule annotationAdd BLAST296

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The GH10 domain binds to xylan.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 10 (cellulase F) family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008797_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O80596

Identification of Orthologs from Complete Genome Data

More...
OMAi
NIITNHD

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O80596

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.260, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003305, CenC_carb-bd
IPR008979, Galactose-bd-like_sf
IPR001000, GH10
IPR031158, GH10_AS
IPR017853, Glycoside_hydrolase_SF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02018, CBM_4_9, 4 hits
PF00331, Glyco_hydro_10, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00633, Glyco_10, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785, SSF49785, 4 hits
SSF51445, SSF51445, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00591, GH10_1, 1 hit
PS51760, GH10_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O80596-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADLNIVMNG DFFAGIEPWY PNGCEAFVVS SDPFSSEVMS ADSSSGGYVV
60 70 80 90 100
VTNRKETWQG LEQDITTRVA SGMNYTVSTC VGVSGPFNES AEVLSTVRLE
110 120 130 140 150
HEDSPTEYLC IGKTYASRDK WVDLEGTFSI SNMPDRVVLY LEGPAPGKDL
160 170 180 190 200
LIRSVTVRSS TSSDFQETEK NTDASNVFPL ALNIIKNHDF SDGLYSWNTN
210 220 230 240 250
GCDSFVVSSN DCNLESNAVV NNRSETWQGL EQDITDNVSP GFSYKVSASV
260 270 280 290 300
SVSGPVLGSA QVLATLKLEH KSSATEFQLI GKTYASKDIW KTLEGTFEVS
310 320 330 340 350
GRPDRVVFFL EGPPPGIDLL VKSVTIHCES DNQFERSREF CSAPESDNHI
360 370 380 390 400
FLNSSFSDGL NHWSGRGCNL MLHESLADGK ILPDSGTCFA SASERTHKWS
410 420 430 440 450
GIEQDITERV QRKLIYEASS VVRLSHSHHT VQATLYVQYL DQREEYIGIS
460 470 480 490 500
SVQGTHDDWV ELKGKFLLNG SPARAVVYIE GPPPGIDVFV DHFAVKPAEK
510 520 530 540 550
ETPSGRPYIE SHAFGMNIVS NSHLSDGTIE GWFPLGDCHL KVGDGSPRIL
560 570 580 590 600
PPLARDSLRK TQGYLSGRYV LATNRSGTWM GPAQTITDKV KLFVTYQVSA
610 620 630 640 650
WVKIGSGGRT SPQDVNIALS VDGNWVNGGK VEVDDGDWHE VVGSFRIEKE
660 670 680 690 700
AKEVMLHVQG PSPGVDLMVA GLQIFAVDRK ARLSYLRGQA DVVRKRNVCL
710 720 730 740 750
KFSGLDPSEL SGATVKIRQT RNSFPLGSCI SRSNIDNEDF VDFFLNNFDW
760 770 780 790 800
AVFGYELKWY WTEPEQGNFN YRDANEMIEF CERYNIKTRG HCIFWEVESA
810 820 830 840 850
IQPWVQQLTG SKLEAAVENR VTDLLTRYNG KFRHYDVNNE MLHGSFYRDR
860 870 880 890 900
LDSDARANMF KTAHELDPLA TLFLNEYHIE DGFDSRSSPE KYIKLVHKLQ
910 920 930 940 950
KKGAPVGGIG IQGHITSPVG HIVRSALDKL STLGLPIWFT ELDVSSTNEH
960 970 980 990 1000
IRGDDLEVML WEAFAHPAVE GVMLWGFWEL FMSREHSHLV NADGEVNEAG
1010 1020 1030 1040 1050
KRFLEIKREW LSFVDGEIED GGGLEFRGYH GSYTVEVVTS ESKYVTNFVV
1060
DKGNSPVDVI IDL
Length:1,063
Mass (Da):118,371
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i78F24C1749ACB841
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8AUA7A0A1P8AUA7_ARATH
Glycosyl hydrolase family 10 protei...
ATXYN2 At1g10050, T27I1.7, T27I1_7
1,095Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC004122 Genomic DNA Translation: AAC34334.1
CP002684 Genomic DNA Translation: AEE28533.1
CP002684 Genomic DNA Translation: ANM60238.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T00624

NCBI Reference Sequences

More...
RefSeqi
NP_001322538.1, NM_001331878.1
NP_172476.1, NM_100879.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G10050.1; AT1G10050.1; AT1G10050
AT1G10050.2; AT1G10050.2; AT1G10050

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
837540

Gramene; a comparative resource for plants

More...
Gramenei
AT1G10050.1; AT1G10050.1; AT1G10050
AT1G10050.2; AT1G10050.2; AT1G10050

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G10050

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004122 Genomic DNA Translation: AAC34334.1
CP002684 Genomic DNA Translation: AEE28533.1
CP002684 Genomic DNA Translation: ANM60238.1
PIRiT00624
RefSeqiNP_001322538.1, NM_001331878.1
NP_172476.1, NM_100879.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

CAZyiCBM22, Carbohydrate-Binding Module Family 22
GH10, Glycoside Hydrolase Family 10

PTM databases

iPTMnetiO80596

Proteomic databases

PaxDbiO80596
PRIDEiO80596
ProteomicsDBi242379

Genome annotation databases

EnsemblPlantsiAT1G10050.1; AT1G10050.1; AT1G10050
AT1G10050.2; AT1G10050.2; AT1G10050
GeneIDi837540
GrameneiAT1G10050.1; AT1G10050.1; AT1G10050
AT1G10050.2; AT1G10050.2; AT1G10050
KEGGiath:AT1G10050

Organism-specific databases

AraportiAT1G10050
TAIRilocus:2201911, AT1G10050

Phylogenomic databases

HOGENOMiCLU_008797_0_0_1
InParanoidiO80596
OMAiNIITNHD
PhylomeDBiO80596

Enzyme and pathway databases

UniPathwayiUPA00114

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O80596

Gene expression databases

ExpressionAtlasiO80596, baseline and differential

Family and domain databases

Gene3Di2.60.120.260, 4 hits
InterProiView protein in InterPro
IPR003305, CenC_carb-bd
IPR008979, Galactose-bd-like_sf
IPR001000, GH10
IPR031158, GH10_AS
IPR017853, Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF02018, CBM_4_9, 4 hits
PF00331, Glyco_hydro_10, 1 hit
SMARTiView protein in SMART
SM00633, Glyco_10, 1 hit
SUPFAMiSSF49785, SSF49785, 4 hits
SSF51445, SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS00591, GH10_1, 1 hit
PS51760, GH10_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiXYN2_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O80596
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2018
Last sequence update: November 1, 1998
Last modified: October 7, 2020
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. SIMILARITY comments
    Index of protein domains and families
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