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Protein

Serine/threonine-protein phosphatase

Gene

PpN58A

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • protein serine/threonine phosphatase activity Source: FlyBase

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation
LigandManganeseSAAS annotation, Metal-bindingSAAS annotation

Enzyme and pathway databases

SignaLinkiO77294

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
Gene namesi
Name:PpN58AImported
Synonyms:PPN 58AImported
ORF Names:CG3245Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0025573 PpN58A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiO77294

Expressioni

Gene expression databases

BgeeiFBgn0025573 Expressed in 7 organ(s), highest expression level in testis
ExpressionAtlasiO77294 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliO77294
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini134 – 139SER_THR_PHOSPHATASEInterPro annotation6

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IN82 Eukaryota
ENOG410Y2WA LUCA
HOGENOMiHOG000252499
OrthoDBiEOG091G0DV9

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
IPR031675 STPPase_N
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PF16891 STPPase_N, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

O77294-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMKKLLSNGS NKNKTLKFDE GINLDQIIAK LKLIGEIGSV IQISVREIEA
60 70 80 90 100
VCSRAREVLL KQPTLLEIPA PINLLGDIHG QYLNLLRYFE SNGYPPDSVY
110 120 130 140 150
LLLGDYVDRG KQSIETLTLL LALKARYPTK FYLLRGNHEC SSINHFYGFY
160 170 180 190 200
DECKRRYTVK LWRTFVDCYN CLPLAAIIEE NIFCCHGGLS PHLFSMQQIR
210 220 230 240 250
EIRRPIEIPE SGLICDILWS DPDLRIMGWG PNERGVSHTF GSDVVSAFLH
260 270 280 290 300
RFKLNLICRG HQVVEDGYEF FAKRQLITIF SAPNYCGEFD NAGAMMCINQ
310 320
DLLCTFRVQR PILSEQRRLS DISV
Length:324
Mass (Da):37,107
Last modified:November 1, 1998 - v1
Checksum:i196D1CC5F13DCA97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y17355 Genomic DNA Translation: CAA76756.1

Similar proteinsi

Entry informationi

Entry nameiO77294_DROME
AccessioniPrimary (citable) accession number: O77294
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: September 12, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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