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UniProtKB - O76486 (O76486_LEIME)
Protein
Submitted name:
Glucose transporter
Gene
GT1
Organism
Leishmania mexicana
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
GO - Biological processi
- carbohydrate transport Source: UniProtKB-KW
Keywordsi
Biological process | Sugar transportImportedARBA annotation, Transport |
Protein family/group databases
TCDBi | 2.A.1.1.76, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Submitted name: Glucose transporterImported |
Gene namesi | Name:GT1Imported |
Organismi | Leishmania mexicanaImported |
Taxonomic identifieri | 5665 [NCBI] |
Taxonomic lineagei | Eukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania › |
Organism-specific databases
VEuPathDBi | TriTrypDB:LmxM.36.6300 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 201 – 222 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 229 – 249 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 255 – 279 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 291 – 311 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 331 – 351 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 384 – 406 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 418 – 440 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 447 – 468 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 480 – 505 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 559 – 580 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 88 – 581 | MFSInterPro annotationAdd BLAST | 494 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 34 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 584 – 610 | DisorderedSequence analysisAdd BLAST | 27 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationFamily and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 2 hits |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O76486-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPPPQIPQP LKPKKVKLPH TSHAASSFQP SKRHLTPLPL QESKYISEKV
60 70 80 90 100
PNPMKPPIAD GIDEFVEESI SPNKELSPSF FSISNFRMIM VQAIGGCLNG
110 120 130 140 150
YSIGFVGVYS TLFGYSTNCA NFRSERGCTT APNADCQWFA NATGTSYCGW
160 170 180 190 200
PEITCRRTYT YSSVAEMPGA IAQCEADSRC RWSYSAKECQ NPSGYSSSES
210 220 230 240 250
GIFAGSMIAG CLIGSVFAGP LASTIGARLS FLLVGLVGVV SSVMCHVSAS
260 270 280 290 300
ENEFWVLVVG RFVIGLFVGV IGVACPVYTD QNAHPKWKRT IGVMFQVFTT
310 320 330 340 350
LGIFIAAAVG LALGQSTYFD RNKDQMVMAR MQGLCAFSTL FSLLTILLGI
360 370 380 390 400
VMSESRAKFG GDDEEGGIEL DPNEYSYVEM VPRLLMGAVM AGTLQLTGIN
410 420 430 440 450
AVMNYAPAIM GSLGLAPLVG NFVVMLWNFV TTLASIPLSY VFTMRQLFLF
460 470 480 490 500
GSLFTSSMCL FMCGIPVYPG VSKKTEVKNG VAITGILLFI LGFEVCVGPC
510 520 530 540 550
YYVLTQDMFP LSFRPRGASF TQVAQFIFNL IINVCYPIAT EHISGGPSGN
560 570 580 590 600
QDKGQAVAFI FFGCVGMICF IIQVFFLHPW DEKRDGKKRP ATPAGGKREL
610
SSSLSGNRAE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF071217 Genomic DNA Translation: AAC70946.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF071217 Genomic DNA Translation: AAC70946.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
TCDBi | 2.A.1.1.76, the major facilitator superfamily (mfs) |
Organism-specific databases
VEuPathDBi | TriTrypDB:LmxM.36.6300 |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 2 hits |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | O76486_LEIME | |
Accessioni | O76486Primary (citable) accession number: O76486 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1998 |
Last sequence update: | November 1, 1998 | |
Last modified: | January 19, 2022 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |