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Entry version 152 (07 Oct 2020)
Sequence version 1 (01 Nov 1998)
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Protein

DNA repair and recombination protein RAD54-like

Gene

okr

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in mitotic DNA repair and meiotic recombination. Functions in the recombinational DNA repair pathway. Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54.4 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi185 – 192ATPCurated8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Helicase, Hydrolase
Biological processCell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA repair and recombination protein RAD54-like1 Publication (EC:3.6.4.-)
Short name:
DmRAD541 Publication
Alternative name(s):
Protein okra1 Publication
RAD54 DNA repair proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:okrImported
Synonyms:RAD54Imported
ORF Names:CG3736
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2L

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0002989, okr

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Eggs and embryos exhibit variable alterations along the dorsal-ventral and anterior-posterior axes. There is a reduction in the level of meiotic recombination and an increase in the frequency of non-disjunction. Larvae have increased sensitivity to ionizing radiation and MMS.2 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi2 – 9Missing : Reduced ATPase activity and loss of chromatin remodeling and strand pairing activities. 1 Publication8
Mutagenesisi191K → A: No ATPase or chromatin remodeling activity. 1 Publication1
Mutagenesisi191K → R: Partial ATPase and low chromatin remodeling activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003925221 – 784DNA repair and recombination protein RAD54-likeAdd BLAST784

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei20Phosphoserine1 Publication1
Modified residuei22Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O76460

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O76460

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed both maternally and zygotically at all stages of fly development.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0002989, Expressed in embryo and 17 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O76460, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via N-terminus) with spn-A/Rad51.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
59726, 28 interactors

Protein interaction database and analysis system

More...
IntActi
O76460, 5 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0077357

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O76460

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini172 – 346Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST175
Domaini503 – 660Helicase C-terminalPROSITE-ProRule annotationAdd BLAST158

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2 – 9Required for chromatin remodeling, strand pairing activities and coupling of ATPase activity1 Publication8

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi297 – 300DEGH boxSequence analysis4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.Sequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0390, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156897

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000315_10_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O76460

KEGG Orthology (KO)

More...
KOi
K10875

Identification of Orthologs from Complete Genome Data

More...
OMAi
GMVICDE

Database of Orthologous Groups

More...
OrthoDBi
93727at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O76460

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR027417, P-loop_NTPase
IPR013967, Rad54_N
IPR038718, SNF2-like_sf
IPR000330, SNF2_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00271, Helicase_C, 1 hit
PF08658, Rad54_N, 1 hit
PF00176, SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487, DEXDc, 1 hit
SM00490, HELICc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O76460-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRSLAPSQR GPLRPESRHS FTPPLLKKNK RSCQQELERE QELDRRRLGA
60 70 80 90 100
LRDASNTSEL PLPIRFTANS EYELAIAKVL ARKFKVPMDN YVPDYGGKRV
110 120 130 140 150
LGVRRCISRR PLHDPMACNA LVLFHPPAYT EHERMGMDPT KVLVHVVVDP
160 170 180 190 200
LLSNILRPHQ REGVRFMYEC VEGKRGNFNG CIMADEMGLG KTLQCVTLVW
210 220 230 240 250
TLLRQGPECK PTINKAIVVS PSSLVKNWEK EFTKWLHGRL LCLPMEGGTK
260 270 280 290 300
ENTIRALEQF SMTSARLGTP VLLISYETFR IYAEILCKYE VGMVICDEGH
310 320 330 340 350
RLKNSDNLTY QALMGLKTKR RVLLSGTPIQ NDLTEYYSLV NFVNPEMLGT
360 370 380 390 400
AAVFKRNFES AILRGQNTDS TEQERQRAIE KTQELIGLVD QCIIRRTNQI
410 420 430 440 450
LTKYLPVKFE MVICAKLTAI QLELYTNFLK SDQVRRSLAD CNEKASLTAL
460 470 480 490 500
ADITTLKKIC SHPDLIYEKL TAREKGFENS QNVLPSNYKP KDLNPELSGK
510 520 530 540 550
FMLLDFMLAA IRAEGNDKVV LISNYTQTLD LFEQLARKRK YGFVRLDGTM
560 570 580 590 600
SIKKRSKVVD RFNDPESDSF LFMLSSKAGG CGLNLIGANR LFMFDPDWNP
610 620 630 640 650
ANDEQAMARV WRDGQKKPCY IYRLVASGSI EEKILQRQTH KKSLSSTIID
660 670 680 690 700
NNESAEKHFT RDDLKDLFTF DANILSDTHD KLKCKRCVQN IQMKPPPEDT
710 720 730 740 750
DCTSHLSQWY HCSNNRGLPD NILAQAWMDC KCVSFVFHHR SQAQEIVPSA
760 770 780
EEEATDQPEE KPESRKRSST PASDDSADED FRGF
Length:784
Mass (Da):89,534
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB7B27FFF61C3AF63
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAL39744 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti761K → N in CAA71278 (PubMed:9315669).Curated1
Sequence conflicti761K → N in AAC26857 (PubMed:9732269).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Y10229 Genomic DNA Translation: CAA71278.1
AF069779 Genomic DNA Translation: AAC24577.1
AF069780 mRNA Translation: AAC26857.1
AE014134 Genomic DNA Translation: AAF51168.1
AY069599 mRNA Translation: AAL39744.2 Different initiation.
FJ219215 Genomic DNA Translation: ACI97200.1
FJ219218 Genomic DNA Translation: ACI97203.1
FJ219219 Genomic DNA Translation: ACI97204.1
FJ219220 Genomic DNA Translation: ACI97205.1
FJ219221 Genomic DNA Translation: ACI97206.1
FJ219222 Genomic DNA Translation: ACI97207.1
FJ219223 Genomic DNA Translation: ACI97208.1
FJ219224 Genomic DNA Translation: ACI97209.1
FJ219225 Genomic DNA Translation: ACI97210.1
FJ219226 Genomic DNA Translation: ACI97211.1
FJ219227 Genomic DNA Translation: ACI97212.1
FJ219228 Genomic DNA Translation: ACI97213.1
FJ219229 Genomic DNA Translation: ACI97214.1
FJ219230 Genomic DNA Translation: ACI97215.1
FJ219231 Genomic DNA Translation: ACI97216.1
FJ219232 Genomic DNA Translation: ACI97217.1
FJ219233 Genomic DNA Translation: ACI97218.1
FJ219234 Genomic DNA Translation: ACI97219.1
FJ219235 Genomic DNA Translation: ACI97220.1
FJ219236 Genomic DNA Translation: ACI97221.1
FJ219237 Genomic DNA Translation: ACI97222.1
FJ219238 Genomic DNA Translation: ACI97223.1
FJ219239 Genomic DNA Translation: ACI97224.1
FJ219240 Genomic DNA Translation: ACI97225.1
FJ219241 Genomic DNA Translation: ACI97226.1
FJ219242 Genomic DNA Translation: ACI97227.1
FJ219243 Genomic DNA Translation: ACI97228.1
FJ219244 Genomic DNA Translation: ACI97229.1
FJ219245 Genomic DNA Translation: ACI97230.1
FJ219246 Genomic DNA Translation: ACI97231.1
FJ219247 Genomic DNA Translation: ACI97232.1

NCBI Reference Sequences

More...
RefSeqi
NP_476661.1, NM_057313.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0077673; FBpp0077357; FBgn0002989

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
33507

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG3736

UCSC genome browser

More...
UCSCi
CG3736-RA, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10229 Genomic DNA Translation: CAA71278.1
AF069779 Genomic DNA Translation: AAC24577.1
AF069780 mRNA Translation: AAC26857.1
AE014134 Genomic DNA Translation: AAF51168.1
AY069599 mRNA Translation: AAL39744.2 Different initiation.
FJ219215 Genomic DNA Translation: ACI97200.1
FJ219218 Genomic DNA Translation: ACI97203.1
FJ219219 Genomic DNA Translation: ACI97204.1
FJ219220 Genomic DNA Translation: ACI97205.1
FJ219221 Genomic DNA Translation: ACI97206.1
FJ219222 Genomic DNA Translation: ACI97207.1
FJ219223 Genomic DNA Translation: ACI97208.1
FJ219224 Genomic DNA Translation: ACI97209.1
FJ219225 Genomic DNA Translation: ACI97210.1
FJ219226 Genomic DNA Translation: ACI97211.1
FJ219227 Genomic DNA Translation: ACI97212.1
FJ219228 Genomic DNA Translation: ACI97213.1
FJ219229 Genomic DNA Translation: ACI97214.1
FJ219230 Genomic DNA Translation: ACI97215.1
FJ219231 Genomic DNA Translation: ACI97216.1
FJ219232 Genomic DNA Translation: ACI97217.1
FJ219233 Genomic DNA Translation: ACI97218.1
FJ219234 Genomic DNA Translation: ACI97219.1
FJ219235 Genomic DNA Translation: ACI97220.1
FJ219236 Genomic DNA Translation: ACI97221.1
FJ219237 Genomic DNA Translation: ACI97222.1
FJ219238 Genomic DNA Translation: ACI97223.1
FJ219239 Genomic DNA Translation: ACI97224.1
FJ219240 Genomic DNA Translation: ACI97225.1
FJ219241 Genomic DNA Translation: ACI97226.1
FJ219242 Genomic DNA Translation: ACI97227.1
FJ219243 Genomic DNA Translation: ACI97228.1
FJ219244 Genomic DNA Translation: ACI97229.1
FJ219245 Genomic DNA Translation: ACI97230.1
FJ219246 Genomic DNA Translation: ACI97231.1
FJ219247 Genomic DNA Translation: ACI97232.1
RefSeqiNP_476661.1, NM_057313.5

3D structure databases

SMRiO76460
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi59726, 28 interactors
IntActiO76460, 5 interactors
STRINGi7227.FBpp0077357

PTM databases

iPTMnetiO76460

Proteomic databases

PaxDbiO76460

Genome annotation databases

EnsemblMetazoaiFBtr0077673; FBpp0077357; FBgn0002989
GeneIDi33507
KEGGidme:Dmel_CG3736
UCSCiCG3736-RA, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
33507
FlyBaseiFBgn0002989, okr

Phylogenomic databases

eggNOGiKOG0390, Eukaryota
GeneTreeiENSGT00940000156897
HOGENOMiCLU_000315_10_2_1
InParanoidiO76460
KOiK10875
OMAiGMVICDE
OrthoDBi93727at2759
PhylomeDBiO76460

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
33507, 0 hits in 5 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
okr, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
33507

Protein Ontology

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PROi
PR:O76460

Gene expression databases

BgeeiFBgn0002989, Expressed in embryo and 17 other tissues
GenevisibleiO76460, DM

Family and domain databases

Gene3Di3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR027417, P-loop_NTPase
IPR013967, Rad54_N
IPR038718, SNF2-like_sf
IPR000330, SNF2_N
PfamiView protein in Pfam
PF00271, Helicase_C, 1 hit
PF08658, Rad54_N, 1 hit
PF00176, SNF2_N, 1 hit
SMARTiView protein in SMART
SM00487, DEXDc, 1 hit
SM00490, HELICc, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRAD54_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O76460
Secondary accession number(s): B6UXG7
, B6UXH8, B6UXJ2, B6UXJ5, P91636, Q7K0T1, Q7KPH9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: November 1, 1998
Last modified: October 7, 2020
This is version 152 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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