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Protein

Neural hemoglobin

Gene
N/A
Organism
Cerebratulus lacteus (Milky ribbon worm) (Micrura lactea)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts as an oxygen store capable of sustaining neuronal activity in an anoxic environment for 5 to 30 min.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi70Iron (heme proximal ligand)1

GO - Molecular functioni

Keywordsi

Biological processOxygen transport, Transport
LigandHeme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Neural hemoglobin
Short name:
NrHb
OrganismiCerebratulus lacteus (Milky ribbon worm) (Micrura lactea)
Taxonomic identifieri6221 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaNemerteaPilidiophoraHeteronemerteaCerebratulidaeCerebratulus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000524992 – 110Neural hemoglobinAdd BLAST109

Proteomic databases

PRIDEiO76242

Interactioni

Subunit structurei

Homotetramer. Self-associates in the deoxy state. Seems to dissociate upon oxygenation.1 Publication

Structurei

Secondary structure

1110
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliO76242
SMRiO76242
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO76242

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.Curated

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
PfamiView protein in Pfam
PF00042 Globin, 1 hit
SUPFAMiSSF46458 SSF46458, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O76242-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVNWAAVVDD FYQELFKAHP EYQNKFGFKG VALGSLKGNA AYKTQAGKTV
60 70 80 90 100
DYINAAIGGS ADAAGLASRH KGRNVGSAEF HNAKACLAKA CSAHGAPDLG
110
HAIDDILSHL
Length:110
Mass (Da):11,530
Last modified:January 23, 2007 - v3
Checksum:i0F30C4420773F244
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033001 Genomic DNA Translation: AAC39125.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF033001 Genomic DNA Translation: AAC39125.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1KR7X-ray1.50A1-110[»]
1V07X-ray1.70A2-110[»]
2VYYX-ray1.60A1-110[»]
2VYZX-ray1.80A1-110[»]
2XKGX-ray1.60A1-110[»]
2XKHX-ray2.31A1-110[»]
2XKIX-ray1.30A1-110[»]
4AVDX-ray1.50A1-110[»]
4AVEX-ray1.90A1-110[»]
4F68X-ray1.80A1-110[»]
4F69X-ray1.60A1-110[»]
4F6BX-ray1.64A1-110[»]
4F6DX-ray1.80A1-110[»]
4F6FX-ray1.56A1-110[»]
4F6GX-ray1.64A1-110[»]
4F6IX-ray1.56A1-110[»]
4F6JX-ray1.45A1-110[»]
ProteinModelPortaliO76242
SMRiO76242
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiO76242

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiO76242

Family and domain databases

Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
PfamiView protein in Pfam
PF00042 Globin, 1 hit
SUPFAMiSSF46458 SSF46458, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLBN_CERLA
AccessioniPrimary (citable) accession number: O76242
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 91 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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