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1 to 25 of 66  Show
  1. 1
    "Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity."
    Pessino A., Sivori S., Bottino C., Malaspina A., Morelli L., Moretta L., Biassoni R., Moretta A.
    J. Exp. Med. 188:953-960(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4), FUNCTION, TISSUE SPECIFICITY, GLYCOSYLATION, INTERACTION WITH CD247.
    Category: Function, PTM / Processing, Expression, Interaction, Sequences.
    Tissue: Lymphoid tissue.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 1 other entry.

  2. 2
    Lin L., Yu R., Zhong J., Li H., Zhou G., Shen C., Ke R., Zheng G., Yang S.
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5572 other entries.

  4. 4
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
    Category: Sequences.
    Tissue: Blood.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50477 other entries.

  6. 6
    "Human natural killer cell receptors: insights into their molecular function and structure."
    Biassoni R., Cantoni C., Marras D., Giron-Michel J., Falco M., Moretta L., Dimasi N.
    J. Cell. Mol. Med. 7:376-387(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.
    Source: UniProtKB/Swiss-Prot (reviewed).
  7. 7
    Cited for: X-RAY CRYSTALLOGRAPHY (1.93 ANGSTROMS) OF 25-212, DISULFIDE BONDS.
    Category: PTM / Processing, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptors."
    Foster C.E., Colonna M., Sun P.D.
    J. Biol. Chem. 278:46081-46086(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 25-212, DISULFIDE BONDS.
    Category: PTM / Processing, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 2 other entries.

  9. 9
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 974 and mapped to 2 other entries.

  10. 10
    "The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium."
    Vankayalapati R., Wizel B., Weis S.E., Safi H., Lakey D.L., Mandelboim O., Samten B., Porgador A., Barnes P.F.
    J. Immunol. 168:3451-3457(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The NKp46 receptor participates in NK cell-mediated lysis of cells infected with the intracellular pathogen Mycobacterium tuberculosis an activity that is reduced in tuberculosis patients compared with findings in healthy donors.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 3 other entries.

  11. 11
    "Selective cross-talk among natural cytotoxicity receptors in human natural killer cells."
    Augugliaro R., Parolini S., Castriconi R., Marcenaro E., Cantoni C., Nanni M., Moretta L., Moretta A., Bottino C.
    Eur. J. Immunol. 33:1235-1241(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: Selective cross-talk among natural cytotoxicity receptors (NKp46 NKp30 and NKp44) in human natural killer cells.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 7 other entries.

  12. 12
    "The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46."
    Arnon T.I., Achdout H., Lieberman N., Gazit R., Gonen-Gross T., Katz G., Bar-Ilan A., Bloushtain N., Lev M., Joseph A., Kedar E., Porgador A., Mandelboim O.
    Blood 103:664-672(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: NKp46 interacts with both viral hemagglutinins and the unknown tumor ligands via different mechanisms.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 3 other entries.

  13. 13
    "CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity."
    Marcenaro E., Augugliaro R., Falco M., Castriconi R., Parolini S., Sivori S., Romeo E., Millo R., Moretta L., Bottino C., Moretta A.
    Eur. J. Immunol. 33:3367-3376(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: CD59 is physically associated with NKp46 and NKp30 and activate human nk cell-mediated cytotoxicity.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 8 other entries.

  14. 14
    "HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells."
    Carbone E., Neri P., Mesuraca M., Fulciniti M.T., Otsuki T., Pende D., Groh V., Spies T., Pollio G., Cosman D., Catalano L., Tassone P., Rotoli B., Venuta S.
    Blood 105:251-258(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: natural cytotoxicity receptor (NCR) and NK receptor member D of the lectin-like receptor family (NKG2D) were the key NK activating receptors for bone marrow-derived myeloma cell recognitionImported.
    Source: GeneRIF:9437.

    This publication is mapped to 6 other entries.

  15. 15
    "Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias."
    Nowbakht P., Ionescu M.C., Rohner A., Kalberer C.P., Rossy E., Mori L., Cosman D., De Libero G., Wodnar-Filipowicz A.
    Blood 105:3615-3622(2005) [PubMed] [Europe PMC] [Abstract]
    Annotation: NKG2D NKp30 NKp44 and NKp46 acitvation affected by ligand-negative phenotype in bone marrow-derived progenitor cells acquisition of cell-surface ligands during myeloid differentiation defective expression of ligands on malignant transformationImported.
    Source: GeneRIF:9437.

    This publication is mapped to 10 other entries.

  16. 16
    "Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors."
    Poggi A., Massaro A.M., Negrini S., Contini P., Zocchi M.R.
    J. Immunol. 174:2653-2660(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: NKp46 is not only a triggering molecule essential for antitumor activity but is also a surface receptor involved in natural killer cell suicide.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 7 other entries.

  17. 17
    "Characterization of the heparin/heparan sulfate binding site of the natural cytotoxicity receptor NKp46."
    Zilka A., Landau G., Hershkovitz O., Bloushtain N., Bar-Ilan A., Benchetrit F., Fima E., van Kuppevelt T.H., Gallagher J.T., Elgavish S., Porgador A.
    Biochemistry 44:14477-14485(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Results examine residues in NKp46 that may be involved in heparan sulfate binding on tumor cells.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 3 other entries.

  18. 18
    "Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells."
    Hermann E., Alonso-Vega C., Berthe A., Truyens C., Flores A., Cordova M., Moretta L., Torrico F., Braud V., Carlier Y.
    Pediatr. Res. 60:38-43(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: defect in cytotoxic effector function is associated with a reduced surface expression of activating NK receptors (NKp30 NKp46 and NKG2D) on CD56(dim) NK cells compared with uninfected newborns.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 9 other entries.

  19. 19
    "Vimentin expressed on Mycobacterium tuberculosis-infected human monocytes is involved in binding to the NKp46 receptor."
    Garg A., Barnes P.F., Porgador A., Roy S., Wu S., Nanda J.S., Griffith D.E., Girard W.M., Rawal N., Shetty S., Vankayalapati R.
    J. Immunol. 177:6192-6198(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Subcellular Location, Interaction.
    Annotation: Vimentin is involved in binding of NKp46 to M. tuberculosis H37Ra-infected mononuclear phagocytes.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 10 other entries.

  20. 20
    "The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells."
    El-Sherbiny Y.M., Meade J.L., Holmes T.D., McGonagle D., Mackie S.L., Morgan A.W., Cook G., Feyler S., Richards S.J., Davies F.E., Morgan G.J., Cook G.P.
    Cancer Res. 67:8444-8449(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The natural cytotoxicity receptor NKp46 was required for the killing of all myeloma cell lines analyzed.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 5 other entries.

  21. 21
    "Expression of ligands to NKp46 in benign and malignant melanocytes."
    Cagnano E., Hershkovitz O., Zilka A., Bar-Ilan A., Golder A., Sion-Vardy N., Bogdanov-Berezovsky A., Mandelboim O., Benharroch D., Porgador A.
    J. Invest. Dermatol. 128:972-979(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: There is a correlation between the malignant potential of the lesion and the expression of NKp46 ligands in the reticular dermis.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 3 other entries.

  22. 22
    "Expressions of natural cytotoxicity receptors and NKG2D on decidual natural killer cells in patients having spontaneous abortions."
    Zhang Y., Zhao A., Wang X., Shi G., Jin H., Lin Q.
    Fertil. Steril. 90:1931-1937(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Determined expressions of NKp46 in decidual natural killer cells in patients having spontaneous abortions.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 7 other entries.

  23. 23
    "Up-regulation of NK cell activating receptors following allogeneic hematopoietic stem cell transplantation under a lymphodepleting reduced intensity regimen is associated with elevated IL-15 levels."
    Boyiadzis M., Memon S., Carson J., Allen K., Szczepanski M.J., Vance B.A., Dean R., Bishop M.R., Gress R.E., Hakim F.T.
    Biol. Blood Marrow Transplant. 14:290-300(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: in NK cells cultured with IL-15 we observed an up-regulation of the activating receptors NKG2D NKp30 and NKp46 associated with an increase in anti-tumor lytic activity.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 9 other entries.

  24. 24
    "Critical and differential roles of NKp46- and NKp30-activating receptors expressed by uterine NK cells in early pregnancy."
    El Costa H., Casemayou A., Aguerre-Girr M., Rabot M., Berrebi A., Parant O., Clouet-Delannoy M., Lombardelli L., Jabrane-Ferrat N., Rukavina D., Bensussan A., Piccinni M.P., Le Bouteiller P., Tabiasco J.
    J. Immunol. 181:3009-3017(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: differential controlled role of NKp46- and NKp30-activating receptors expressed by uterine dNK that could be critical for the outcome of pregnancyImported.
    Source: GeneRIF:9437.

    This publication is mapped to 6 other entries.

  25. 25
    "Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition."
    Lunemann A., Lunemann J.D., Roberts S., Messmer B., Barreira da Silva R., Raine C.S., Munz C.
    J. Immunol. 181:6170-6177(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Brain-infiltrating natural killer (NK) cells might restrict innate and adaptive immune responses via elimination of resting microglia; this cell killing is dependent on cell contact NKp46 and NKG2D.Imported.
    Source: GeneRIF:9437.

    This publication is mapped to 6 other entries.

1 to 25 of 66  Show
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