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UniProtKB - O76027 (ANXA9_HUMAN)

Entry version 171 (02 Dec 2020)
Sequence version 3 (20 Mar 2007)
Previous versions | rss
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Protein

Annexin A9

Gene

ANXA9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O76027

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Annexin A9
Alternative name(s):
Annexin XXXI
Annexin-31
Annexin-9
Pemphaxin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANXA9
Synonyms:ANX31
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000143412.9

Human Gene Nomenclature Database

More...HGNCi		HGNC:547, ANXA9

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		603319, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O76027

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		8416

Open Targets

More...OpenTargetsi		ENSG00000143412

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA24837

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O76027, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ANXA9

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000675051 – 345Annexin A9Add BLAST345

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O76027

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O76027

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O76027

MaxQB - The MaxQuant DataBase

More...MaxQBi		O76027

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O76027

PeptideAtlas

More...PeptideAtlasi		O76027

PRoteomics IDEntifications database

More...PRIDEi		O76027

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		50350

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O76027

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O76027

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000143412, Expressed in lower esophagus mucosa and 159 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O76027, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000143412, Tissue enhanced (ductus deferens, seminal vesicle)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		114002, 6 interactors

Protein interaction database and analysis system

More...IntActi		O76027, 4 interactors

Molecular INTeraction database

More...MINTi		O76027

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000357943

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O76027, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O76027

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati41 – 112Annexin 1PROSITE-ProRule annotationAdd BLAST72
Repeati113 – 184Annexin 2PROSITE-ProRule annotationAdd BLAST72
Repeati197 – 266Annexin 3PROSITE-ProRule annotationAdd BLAST70
Repeati270 – 341Annexin 4PROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the annexin family.PROSITE-ProRule annotationCurated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Annexin, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0819, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161835

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_025300_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O76027

Identification of Orthologs from Complete Genome Data

More...OMAi		VYKHNFQ

Database of Orthologous Groups

More...OrthoDBi		856254at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O76027

TreeFam database of animal gene trees

More...TreeFami		TF105452

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.220.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001464, Annexin
IPR018502, Annexin_repeat
IPR018252, Annexin_repeat_CS
IPR037104, Annexin_sf
IPR009116, ANX9

The PANTHER Classification System

More...PANTHERi		PTHR10502:SF122, PTHR10502:SF122, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00191, Annexin, 4 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00196, ANNEXIN
PR01812, ANNEXINXXXI

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00335, ANX, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47874, SSF47874, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00223, ANNEXIN_1, 1 hit
PS51897, ANNEXIN_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O76027-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVTGGKMAP SLTQEILSHL GLASKTAAWG TLGTLRTFLN FSVDKDAQRL 
        60         70         80         90        100
LRAITGQGVD RSAIVDVLTN RSREQRQLIS RNFQERTQQD LMKSLQAALS 
       110        120        130        140        150
GNLERIVMAL LQPTAQFDAQ ELRTALKASD SAVDVAIEIL ATRTPPQLQE 
       160        170        180        190        200
CLAVYKHNFQ VEAVDDITSE TSGILQDLLL ALAKGGRDSY SGIIDYNLAE 
       210        220        230        240        250
QDVQALQRAE GPSREETWVP VFTQRNPEHL IRVFDQYQRS TGQELEEAVQ 
       260        270        280        290        300
NRFHGDAQVA LLGLASVIKN TPLYFADKLH QALQETEPNY QVLIRILISR 
       310        320        330        340 
CETDLLSIRA EFRKKFGKSL YSSLQDAVKG DCQSALLALC RAEDM
Length:345
Mass (Da):38,364
Last modified:March 20, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF0FE611CA6D56B9
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH05830 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAA08933 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04825528A → T. Corresponds to variant dbSNP:rs16832595Ensembl.1
Natural variantiVAR_048256114T → A. Corresponds to variant dbSNP:rs7536645Ensembl.1
Natural variantiVAR_048257119A → T. Corresponds to variant dbSNP:rs16832602Ensembl.1
Natural variantiVAR_022814166D → G3 PublicationsCorresponds to variant dbSNP:rs267733Ensembl.1
Natural variantiVAR_031212225R → Q. Corresponds to variant dbSNP:rs775255778Ensembl.1
Natural variantiVAR_048258232R → Q. Corresponds to variant dbSNP:rs7542365Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ009985 mRNA Translation: CAA08933.1 Frameshift.
AF230929 mRNA Translation: AAG16780.1
AL590133 Genomic DNA No translation available.
BC005830 mRNA Translation: AAH05830.2 Different initiation.
CR536481 mRNA Translation: CAG38720.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS975.2

NCBI Reference Sequences

More...RefSeqi		NP_003559.2, NM_003568.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000368947; ENSP00000357943; ENSG00000143412

Database of genes from NCBI RefSeq genomes

More...GeneIDi		8416

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:8416

UCSC genome browser

More...UCSCi		uc001ewa.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ009985 mRNA Translation: CAA08933.1 Frameshift.
AF230929 mRNA Translation: AAG16780.1
AL590133 Genomic DNA No translation available.
BC005830 mRNA Translation: AAH05830.2 Different initiation.
CR536481 mRNA Translation: CAG38720.1
CCDSiCCDS975.2
RefSeqiNP_003559.2, NM_003568.2

3D structure databases

SMRiO76027
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi114002, 6 interactors
IntActiO76027, 4 interactors
MINTiO76027
STRINGi9606.ENSP00000357943

PTM databases

iPTMnetiO76027
PhosphoSitePlusiO76027

Polymorphism and mutation databases

BioMutaiANXA9

Proteomic databases

EPDiO76027
jPOSTiO76027
MassIVEiO76027
MaxQBiO76027
PaxDbiO76027
PeptideAtlasiO76027
PRIDEiO76027
ProteomicsDBi50350

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		34042, 204 antibodies

The DNASU plasmid repository

More...DNASUi		8416

Genome annotation databases

EnsembliENST00000368947; ENSP00000357943; ENSG00000143412
GeneIDi8416
KEGGihsa:8416
UCSCiuc001ewa.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8416
DisGeNETi8416
EuPathDBiHostDB:ENSG00000143412.9

GeneCards: human genes, protein and diseases

More...GeneCardsi		ANXA9
HGNCiHGNC:547, ANXA9
HPAiENSG00000143412, Tissue enhanced (ductus deferens, seminal vesicle)
MIMi603319, gene
neXtProtiNX_O76027
OpenTargetsiENSG00000143412
PharmGKBiPA24837

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0819, Eukaryota
GeneTreeiENSGT00940000161835
HOGENOMiCLU_025300_0_0_1
InParanoidiO76027
OMAiVYKHNFQ
OrthoDBi856254at2759
PhylomeDBiO76027
TreeFamiTF105452

Enzyme and pathway databases

PathwayCommonsiO76027

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		8416, 7 hits in 842 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ANXA9, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ANXA9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		8416
PharosiO76027, Tbio

Protein Ontology

More...PROi		PR:O76027
RNActiO76027, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000143412, Expressed in lower esophagus mucosa and 159 other tissues
GenevisibleiO76027, HS

Family and domain databases

Gene3Di1.10.220.10, 4 hits
InterProiView protein in InterPro
IPR001464, Annexin
IPR018502, Annexin_repeat
IPR018252, Annexin_repeat_CS
IPR037104, Annexin_sf
IPR009116, ANX9
PANTHERiPTHR10502:SF122, PTHR10502:SF122, 1 hit
PfamiView protein in Pfam
PF00191, Annexin, 4 hits
PRINTSiPR00196, ANNEXIN
PR01812, ANNEXINXXXI
SMARTiView protein in SMART
SM00335, ANX, 4 hits
SUPFAMiSSF47874, SSF47874, 1 hit
PROSITEiView protein in PROSITE
PS00223, ANNEXIN_1, 1 hit
PS51897, ANNEXIN_2, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiANXA9_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O76027
Secondary accession number(s): Q5SZF1
, Q6FI55, Q9BS00, Q9HBJ6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: March 20, 2007
Last modified: December 2, 2020
This is version 171 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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