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UniProtKB - O75954 (TSN9_HUMAN)

Entry version 146 (10 Feb 2021)
Sequence version 1 (01 Nov 1998)
Previous versions | rss
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Protein

Tetraspanin-9

Gene

TSPAN9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O75954

Protein family/group databases

Transport Classification Database

More...TCDBi		8.A.40.1.22, the tetraspanin (tetraspanin) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tetraspanin-9
Short name:
Tspan-9
Alternative name(s):
Tetraspan NET-5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TSPAN9
Synonyms:NET5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21640, TSPAN9

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		613137, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O75954

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000011105.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 13CytoplasmicSequence analysisAdd BLAST13
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei14 – 34HelicalSequence analysisAdd BLAST21
Topological domaini35 – 55ExtracellularSequence analysisAdd BLAST21
Transmembranei56 – 76HelicalSequence analysisAdd BLAST21
Topological domaini77 – 85CytoplasmicSequence analysis9
Transmembranei86 – 106HelicalSequence analysisAdd BLAST21
Topological domaini107 – 203ExtracellularSequence analysisAdd BLAST97
Transmembranei204 – 224HelicalSequence analysisAdd BLAST21
Topological domaini225 – 239CytoplasmicSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		10867

Open Targets

More...OpenTargetsi		ENSG00000011105

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142670694

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O75954, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TSPAN9

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002192531 – 239Tetraspanin-9Add BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi180N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated.By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O75954

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O75954

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O75954

MaxQB - The MaxQuant DataBase

More...MaxQBi		O75954

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O75954

PeptideAtlas

More...PeptideAtlasi		O75954

PRoteomics IDEntifications database

More...PRIDEi		O75954

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		50320

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		O75954, 1 site

SwissPalm database of S-palmitoylation events

More...SwissPalmi		O75954

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in megakaryocytes and platelets (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000011105, Expressed in cerebellar hemisphere and 233 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O75954, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O75954, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000011105, Tissue enhanced (brain, heart muscle)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Found in a complex with GP6.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		116076, 4 interactors

Protein interaction database and analysis system

More...IntActi		O75954, 4 interactors

Molecular INTeraction database

More...MINTi		O75954

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000011898

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O75954, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O75954

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3882, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158225

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_055524_4_3_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O75954

Identification of Orthologs from Complete Genome Data

More...OMAi		KMWFDEN

Database of Orthologous Groups

More...OrthoDBi		1224210at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O75954

TreeFam database of animal gene trees

More...TreeFami		TF352892

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1450.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000301, Tetraspanin
IPR018499, Tetraspanin/Peripherin
IPR018503, Tetraspanin_CS
IPR008952, Tetraspanin_EC2_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00335, Tetraspanin, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002419, Tetraspanin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00259, TMFOUR

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48652, SSF48652, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00421, TM4_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

O75954-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARGCLCCLK YMMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS 
        60         70         80         90        100
LSAANLVIAI GTIVMVTGFL GCLGAIKENK CLLLSFFIVL LVILLAELIL 
       110        120        130        140        150
LILFFVYMDK VNENAKKDLK EGLLLYHTEN NVGLKNAWNI IQAEMRCCGV 
       160        170        180        190        200
TDYTDWYPVL GENTVPDRCC MENSQGCGRN ATTPLWRTGC YEKVKMWFDD 
       210        220        230 
NKHVLGTVGM CILIMQILGM AFSMTLFQHI HRTGKKYDA
Length:239
Mass (Da):26,779
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDD7BA332BF6584EB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B5MD23B5MD23_HUMAN
Tetraspanin
TSPAN9
271Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1W2PQ04A0A1W2PQ04_HUMAN
Tetraspanin-9
TSPAN9
176Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3IST1A0A3B3IST1_HUMAN
Tetraspanin-9
TSPAN9
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PHL0E9PHL0_HUMAN
Tetraspanin-9
TSPAN9
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti216Q → R in BAD96899 (Ref. 4) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF089749 mRNA Translation: AAC35859.1
AK027366 mRNA Translation: BAG51307.1
CR542109 mRNA Translation: CAG46906.1
AK223179 mRNA Translation: BAD96899.1
AC005912 Genomic DNA No translation available.
CH471116 Genomic DNA Translation: EAW88868.1
CH471116 Genomic DNA Translation: EAW88869.1
BC071881 mRNA Translation: AAH71881.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS8520.1

NCBI Reference Sequences

More...RefSeqi		NP_001161792.1, NM_001168320.1
NP_006666.1, NM_006675.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000011898; ENSP00000011898; ENSG00000011105
ENST00000537971; ENSP00000444799; ENSG00000011105

Database of genes from NCBI RefSeq genomes

More...GeneIDi		10867

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:10867

UCSC genome browser

More...UCSCi		uc001qlp.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF089749 mRNA Translation: AAC35859.1
AK027366 mRNA Translation: BAG51307.1
CR542109 mRNA Translation: CAG46906.1
AK223179 mRNA Translation: BAD96899.1
AC005912 Genomic DNA No translation available.
CH471116 Genomic DNA Translation: EAW88868.1
CH471116 Genomic DNA Translation: EAW88869.1
BC071881 mRNA Translation: AAH71881.1
CCDSiCCDS8520.1
RefSeqiNP_001161792.1, NM_001168320.1
NP_006666.1, NM_006675.4

3D structure databases

SMRiO75954
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi116076, 4 interactors
IntActiO75954, 4 interactors
MINTiO75954
STRINGi9606.ENSP00000011898

Protein family/group databases

TCDBi8.A.40.1.22, the tetraspanin (tetraspanin) family

PTM databases

GlyGeniO75954, 1 site
SwissPalmiO75954

Genetic variation databases

BioMutaiTSPAN9

Proteomic databases

EPDiO75954
jPOSTiO75954
MassIVEiO75954
MaxQBiO75954
PaxDbiO75954
PeptideAtlasiO75954
PRIDEiO75954
ProteomicsDBi50320

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2820, 149 antibodies

The DNASU plasmid repository

More...DNASUi		10867

Genome annotation databases

EnsembliENST00000011898; ENSP00000011898; ENSG00000011105
ENST00000537971; ENSP00000444799; ENSG00000011105
GeneIDi10867
KEGGihsa:10867
UCSCiuc001qlp.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		10867
DisGeNETi10867

GeneCards: human genes, protein and diseases

More...GeneCardsi		TSPAN9
HGNCiHGNC:21640, TSPAN9
HPAiENSG00000011105, Tissue enhanced (brain, heart muscle)
MIMi613137, gene
neXtProtiNX_O75954
OpenTargetsiENSG00000011105
PharmGKBiPA142670694
VEuPathDBiHostDB:ENSG00000011105.11

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3882, Eukaryota
GeneTreeiENSGT00940000158225
HOGENOMiCLU_055524_4_3_1
InParanoidiO75954
OMAiKMWFDEN
OrthoDBi1224210at2759
PhylomeDBiO75954
TreeFamiTF352892

Enzyme and pathway databases

PathwayCommonsiO75954

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		10867, 1 hit in 875 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TSPAN9, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		10867
PharosiO75954, Tbio

Protein Ontology

More...PROi		PR:O75954
RNActiO75954, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000011105, Expressed in cerebellar hemisphere and 233 other tissues
ExpressionAtlasiO75954, baseline and differential
GenevisibleiO75954, HS

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301, Tetraspanin
IPR018499, Tetraspanin/Peripherin
IPR018503, Tetraspanin_CS
IPR008952, Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335, Tetraspanin, 1 hit
PIRSFiPIRSF002419, Tetraspanin, 1 hit
PRINTSiPR00259, TMFOUR
SUPFAMiSSF48652, SSF48652, 1 hit
PROSITEiView protein in PROSITE
PS00421, TM4_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTSN9_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75954
Secondary accession number(s): D3DUQ7, Q53FV2, Q6FGJ8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1998
Last modified: February 10, 2021
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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