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UniProtKB - O75936 (BODG_HUMAN)

Entry version 180 (23 Feb 2022)
Sequence version 1 (01 Nov 1998)
Previous versions | rss
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Protein

Gamma-butyrobetaine dioxygenase

Gene

BBOX1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: carnitine biosynthesis

This protein is involved in the pathway carnitine biosynthesis, which is part of Amine and polyamine biosynthesis.
View all proteins of this organism that are known to be involved in the pathway carnitine biosynthesis and in Amine and polyamine biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi38Zinc1
Metal bindingi40Zinc1
Metal bindingi43Zinc1
Metal bindingi82Zinc1
Metal bindingi202Iron; catalyticCurated1
Metal bindingi204Iron; catalyticCurated1
Metal bindingi347Iron; catalyticCurated1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDioxygenase, Oxidoreductase
Biological processCarnitine biosynthesis
LigandIron, Metal-binding, Zinc

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		1.14.11.1, 2681

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O75936

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-71262, Carnitine synthesis

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		O75936

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		O75936

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00118

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Gamma-butyrobetaine dioxygenase (EC:1.14.11.1)
Alternative name(s):
Gamma-butyrobetaine hydroxylase
Short name:
Gamma-BBH
Gamma-butyrobetaine,2-oxoglutarate dioxygenase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BBOX1
Synonyms:BBH, BBOX
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:964, BBOX1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		603312, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O75936

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000129151

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		8424

Open Targets

More...OpenTargetsi		ENSG00000129151

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25274

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O75936, Tchem

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL2163175

Drug and drug target database

More...DrugBanki		DB00126, Ascorbic acid

DrugCentral

More...DrugCentrali		O75936

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		BBOX1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002070851 – 387Gamma-butyrobetaine dioxygenaseAdd BLAST387

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei351PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O75936

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O75936

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O75936

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O75936

PeptideAtlas

More...PeptideAtlasi		O75936

PRoteomics IDEntifications database

More...PRIDEi		O75936

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		50301

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O75936

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O75936

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in kidney; moderately expressed in liver; very low expression in brain.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000129151, Expressed in nephron tubule and 177 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O75936, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O75936, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000129151, Group enriched (kidney, liver)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		114008, 26 interactors

Protein interaction database and analysis system

More...IntActi		O75936, 16 interactors

Molecular INTeraction database

More...MINTi		O75936

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000263182

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		O75936

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O75936, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1387
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O75936

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		O75936

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the gamma-BBH/TMLD family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3888, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00530000063582

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_021859_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O75936

Identification of Orthologs from Complete Genome Data

More...OMAi		AFHIADR

Database of Orthologous Groups

More...OrthoDBi		868657at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O75936

TreeFam database of animal gene trees

More...TreeFami		TF313805

Family and domain databases

Database of protein disorder

More...DisProti		DP02678

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.2020.30, 1 hit
3.60.130.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012775, GBBH
IPR010376, GBBH-like_N
IPR038492, GBBH-like_N_sf
IPR042098, TauD-like_sf
IPR003819, TauD/TfdA-like

Pfam protein domain database

More...Pfami		View protein in Pfam
PF06155, GBBH-like_N, 1 hit
PF02668, TauD, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR02409, carnitine_bodg, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O75936-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MACTIQKAEA LDGAHLMQIL WYDEEESLYP AVWLRDNCPC SDCYLDSAKA 
        60         70         80         90        100
RKLLVEALDV NIGIKGLIFD RKKVYITWPD EHYSEFQADW LKKRCFSKQA 
       110        120        130        140        150
RAKLQRELFF PECQYWGSEL QLPTLDFEDV LRYDEHAYKW LSTLKKVGIV 
       160        170        180        190        200
RLTGASDKPG EVSKLGKRMG FLYLTFYGHT WQVQDKIDAN NVAYTTGKLS 
       210        220        230        240        250
FHTDYPALHH PPGVQLLHCI KQTVTGGDSE IVDGFNVCQK LKKNNPQAFQ 
       260        270        280        290        300
ILSSTFVDFT DIGVDYCDFS VQSKHKIIEL DDKGQVVRIN FNNATRDTIF 
       310        320        330        340        350
DVPVERVQPF YAALKEFVDL MNSKESKFTF KMNPGDVITF DNWRLLHGRR 
       360        370        380 
SYEAGTEISR HLEGAYADWD VVMSRLRILR QRVENGN
Length:387
Mass (Da):44,715
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA3BA3F9FA9355DB3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PKC9E9PKC9_HUMAN
Gamma-butyrobetaine dioxygenase
BBOX1
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF082868 mRNA Translation: AAC64066.1
CR456812 mRNA Translation: CAG33093.1
AK313422 mRNA Translation: BAG36214.1
CH471064 Genomic DNA Translation: EAW68290.1
CH471064 Genomic DNA Translation: EAW68291.1
BC011034 mRNA Translation: AAH11034.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS7862.1

Protein sequence database of the Protein Information Resource

More...PIRi		JE0360

NCBI Reference Sequences

More...RefSeqi		NP_003977.1, NM_003986.2
XP_005253216.1, XM_005253159.2
XP_005253217.1, XM_005253160.2
XP_005253218.1, XM_005253161.2
XP_011518704.1, XM_011520402.1
XP_016873892.1, XM_017018403.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000263182; ENSP00000263182; ENSG00000129151
ENST00000525090; ENSP00000433772; ENSG00000129151
ENST00000528583; ENSP00000434918; ENSG00000129151
ENST00000529202; ENSP00000435781; ENSG00000129151

Database of genes from NCBI RefSeq genomes

More...GeneIDi		8424

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:8424

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000263182.8; ENSP00000263182.3; NM_003986.3; NP_003977.1

UCSC genome browser

More...UCSCi		uc001mre.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF082868 mRNA Translation: AAC64066.1
CR456812 mRNA Translation: CAG33093.1
AK313422 mRNA Translation: BAG36214.1
CH471064 Genomic DNA Translation: EAW68290.1
CH471064 Genomic DNA Translation: EAW68291.1
BC011034 mRNA Translation: AAH11034.1
CCDSiCCDS7862.1
PIRiJE0360
RefSeqiNP_003977.1, NM_003986.2
XP_005253216.1, XM_005253159.2
XP_005253217.1, XM_005253160.2
XP_005253218.1, XM_005253161.2
XP_011518704.1, XM_011520402.1
XP_016873892.1, XM_017018403.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3MS5X-ray1.82A1-387[»]
3N6WX-ray2.00A1-387[»]
3O2GX-ray1.78A1-387[»]
4BG1X-ray1.89A1-387[»]
4BGKX-ray2.18A1-387[»]
4BGMX-ray2.40A1-387[»]
4BHFX-ray2.05A1-387[»]
4BHGX-ray1.85A1-387[»]
4BHIX-ray2.15A1-387[»]
4C5WX-ray1.70A1-387[»]
4C8RX-ray2.82A/B/C/D/E/F1-387[»]
4CWDX-ray1.90A1-387[»]
SMRiO75936
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi114008, 26 interactors
IntActiO75936, 16 interactors
MINTiO75936
STRINGi9606.ENSP00000263182

Chemistry databases

BindingDBiO75936
ChEMBLiCHEMBL2163175
DrugBankiDB00126, Ascorbic acid
DrugCentraliO75936

PTM databases

iPTMnetiO75936
PhosphoSitePlusiO75936

Genetic variation databases

BioMutaiBBOX1

Proteomic databases

EPDiO75936
jPOSTiO75936
MassIVEiO75936
PaxDbiO75936
PeptideAtlasiO75936
PRIDEiO75936
ProteomicsDBi50301

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2001, 372 antibodies from 30 providers

The DNASU plasmid repository

More...DNASUi		8424

Genome annotation databases

EnsembliENST00000263182; ENSP00000263182; ENSG00000129151
ENST00000525090; ENSP00000433772; ENSG00000129151
ENST00000528583; ENSP00000434918; ENSG00000129151
ENST00000529202; ENSP00000435781; ENSG00000129151
GeneIDi8424
KEGGihsa:8424
MANE-SelectiENST00000263182.8; ENSP00000263182.3; NM_003986.3; NP_003977.1
UCSCiuc001mre.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8424
DisGeNETi8424

GeneCards: human genes, protein and diseases

More...GeneCardsi		BBOX1
HGNCiHGNC:964, BBOX1
HPAiENSG00000129151, Group enriched (kidney, liver)
MIMi603312, gene
neXtProtiNX_O75936
OpenTargetsiENSG00000129151
PharmGKBiPA25274
VEuPathDBiHostDB:ENSG00000129151

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3888, Eukaryota
GeneTreeiENSGT00530000063582
HOGENOMiCLU_021859_2_0_1
InParanoidiO75936
OMAiAFHIADR
OrthoDBi868657at2759
PhylomeDBiO75936
TreeFamiTF313805

Enzyme and pathway databases

UniPathwayiUPA00118
BRENDAi1.14.11.1, 2681
PathwayCommonsiO75936
ReactomeiR-HSA-71262, Carnitine synthesis
SABIO-RKiO75936
SignaLinkiO75936

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		8424, 4 hits in 1037 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		BBOX1, human
EvolutionaryTraceiO75936

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		Gamma-butyrobetaine_dioxygenase

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		8424
PharosiO75936, Tchem

Protein Ontology

More...PROi		PR:O75936
RNActiO75936, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000129151, Expressed in nephron tubule and 177 other tissues
ExpressionAtlasiO75936, baseline and differential
GenevisibleiO75936, HS

Family and domain databases

DisProtiDP02678
Gene3Di3.30.2020.30, 1 hit
3.60.130.10, 1 hit
InterProiView protein in InterPro
IPR012775, GBBH
IPR010376, GBBH-like_N
IPR038492, GBBH-like_N_sf
IPR042098, TauD-like_sf
IPR003819, TauD/TfdA-like
PfamiView protein in Pfam
PF06155, GBBH-like_N, 1 hit
PF02668, TauD, 1 hit
TIGRFAMsiTIGR02409, carnitine_bodg, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBODG_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75936
Secondary accession number(s): B2R8L7, D3DQZ1, Q6IBJ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1998
Last modified: February 23, 2022
This is version 180 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families
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