UniProtKB - O75891 (AL1L1_HUMAN)
Protein
Cytosolic 10-formyltetrahydrofolate dehydrogenase
Gene
ALDH1L1
Organism
Homo sapiens (Human)
Status
Functioni
Caution
The phosphoserine observed at Ser-354 in PubMed:24275569 may result from secondary neutral loss of pantetheine from the phosphodiester linked cofactor.Curated
Catalytic activityi
- EC:1.5.1.6
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 106 | Proton donorBy similarity | 1 | |
Binding sitei | 142 | Substrate | 1 | |
Sitei | 142 | Essential for catalytic activityBy similarity | 1 | |
Active sitei | 673 | Proton acceptorPROSITE-ProRule annotation | 1 | |
Active sitei | 707 | Proton donorBy similarity | 1 | |
Binding sitei | 757 | NADPBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 571 – 573 | NADPBy similarity | 3 | |
Nucleotide bindingi | 597 – 600 | NADPBy similarity | 4 | |
Nucleotide bindingi | 630 – 635 | NADPBy similarity | 6 | |
Nucleotide bindingi | 650 – 651 | NADPBy similarity | 2 | |
Nucleotide bindingi | 804 – 806 | NADPBy similarity | 3 |
GO - Molecular functioni
- aldehyde dehydrogenase (NAD+) activity Source: GO_Central
- catalytic activity Source: ProtInc
- formyltetrahydrofolate dehydrogenase activity Source: GO_Central
- hydroxymethyl-, formyl- and related transferase activity Source: InterPro
GO - Biological processi
- 10-formyltetrahydrofolate catabolic process Source: ProtInc
- biosynthetic process Source: InterPro
- folic acid metabolic process Source: Reactome
- one-carbon metabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Biological process | One-carbon metabolism |
Ligand | NADP |
Enzyme and pathway databases
BioCyci | MetaCyc:HS07217-MONOMER |
BRENDAi | 1.5.1.6, 2681 |
PathwayCommonsi | O75891 |
Reactomei | R-HSA-196757, Metabolism of folate and pterines |
Names & Taxonomyi
Protein namesi | Recommended name: Cytosolic 10-formyltetrahydrofolate dehydrogenase (EC:1.5.1.6)Short name: 10-FTHFDH Short name: FDH Alternative name(s): Aldehyde dehydrogenase family 1 member L1 |
Gene namesi | Name:ALDH1L1 Synonyms:FTHFD |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000144908.13 |
HGNCi | HGNC:3978, ALDH1L1 |
MIMi | 600249, gene |
neXtProti | NX_O75891 |
Subcellular locationi
Other locations
Cytosol
- cytosol Source: HPA
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Organism-specific databases
DisGeNETi | 10840 |
OpenTargetsi | ENSG00000144908 |
PharmGKBi | PA28393 |
Miscellaneous databases
Pharosi | O75891, Tbio |
Chemistry databases
DrugBanki | DB00116, Tetrahydrofolic acid |
Polymorphism and mutation databases
BioMutai | ALDH1L1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000199419 | 1 – 902 | Cytosolic 10-formyltetrahydrofolate dehydrogenaseAdd BLAST | 902 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 9 | PhosphoserineCombined sources | 1 | |
Modified residuei | 38 | N6-succinyllysineBy similarity | 1 | |
Modified residuei | 354 | O-(pantetheine 4'-phosphoryl)serine; alternatePROSITE-ProRule annotationCurated | 1 | |
Modified residuei | 354 | Phosphoserine; alternateCombined sources | 1 | |
Modified residuei | 629 | PhosphoserineCombined sources | 1 | |
Modified residuei | 631 | PhosphoserineCombined sources | 1 | |
Modified residuei | 660 | N6-succinyllysineBy similarity | 1 | |
Modified residuei | 767 | N6-succinyllysineBy similarity | 1 | |
Modified residuei | 825 | PhosphoserineCombined sources | 1 | |
Modified residuei | 882 | N6-acetyllysineBy similarity | 1 |
Keywords - PTMi
Acetylation, Phosphopantetheine, PhosphoproteinProteomic databases
EPDi | O75891 |
jPOSTi | O75891 |
MassIVEi | O75891 |
MaxQBi | O75891 |
PaxDbi | O75891 |
PeptideAtlasi | O75891 |
PRIDEi | O75891 |
ProteomicsDBi | 19312 50249 [O75891-1] 74038 |
PTM databases
iPTMneti | O75891 |
PhosphoSitePlusi | O75891 |
Expressioni
Tissue specificityi
Highly expressed in liver, pancreas and kidney.1 Publication
Gene expression databases
Bgeei | ENSG00000144908, Expressed in liver and 210 other tissues |
ExpressionAtlasi | O75891, baseline and differential |
Genevisiblei | O75891, HS |
Organism-specific databases
HPAi | ENSG00000144908, Tissue enhanced (kidney, liver) |
Interactioni
Binary interactionsi
Isoform 4 [O75891-4]
With | #Exp. | IntAct |
---|---|---|
APPBP2 [Q92624] | 3 | EBI-12400198,EBI-743771 |
Protein-protein interaction databases
BioGRIDi | 116052, 23 interactors |
IntActi | O75891, 77 interactors |
MINTi | O75891 |
STRINGi | 9606.ENSP00000273450 |
Miscellaneous databases
RNActi | O75891, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | O75891 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | O75891 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 318 – 395 | CarrierPROSITE-ProRule annotationAdd BLAST | 78 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 203 | GARTAdd BLAST | 203 | |
Regioni | 88 – 90 | Substrate binding | 3 | |
Regioni | 417 – 902 | Aldehyde dehydrogenaseAdd BLAST | 486 |
Sequence similaritiesi
In the N-terminal section; belongs to the GART family.Curated
Phylogenomic databases
eggNOGi | KOG2452, Eukaryota |
GeneTreei | ENSGT00940000160913 |
HOGENOMi | CLU_014974_1_0_1 |
InParanoidi | O75891 |
OMAi | ENAKINW |
PhylomeDBi | O75891 |
TreeFami | TF354242 |
Family and domain databases
Gene3Di | 1.10.1200.10, 1 hit 3.10.25.10, 1 hit 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR011407, 10_FTHF_DH IPR036736, ACP-like_sf IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom IPR005793, Formyl_trans_C IPR037022, Formyl_trans_C_sf IPR002376, Formyl_transf_N IPR036477, Formyl_transf_N_sf IPR011034, Formyl_transferase-like_C_sf IPR001555, GART_AS IPR009081, PP-bd_ACP |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit PF02911, Formyl_trans_C, 1 hit PF00551, Formyl_trans_N, 1 hit PF00550, PP-binding, 1 hit |
PIRSFi | PIRSF036489, 10-FTHFDH, 1 hit |
SUPFAMi | SSF47336, SSF47336, 1 hit SSF50486, SSF50486, 1 hit SSF53328, SSF53328, 1 hit SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit PS50075, CARRIER, 1 hit PS00373, GART, 1 hit |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: O75891-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MKIAVIGQSL FGQEVYCHLR KEGHEVVGVF TVPDKDGKAD PLGLEAEKDG
60 70 80 90 100
VPVFKYSRWR AKGQALPDVV AKYQALGAEL NVLPFCSQFI PMEIISAPRH
110 120 130 140 150
GSIIYHPSLL PRHRGASAIN WTLIHGDKKG GFSIFWADDG LDTGDLLLQK
160 170 180 190 200
ECEVLPDDTV STLYNRFLFP EGIKGMVQAV RLIAEGKAPR LPQPEEGATY
210 220 230 240 250
EGIQKKETAK INWDQPAEAI HNWIRGNDKV PGAWTEACEQ KLTFFNSTLN
260 270 280 290 300
TSGLVPEGDA LPIPGAHRPG VVTKAGLILF GNDDKMLLVK NIQLEDGKMI
310 320 330 340 350
LASNFFKGAA SSVLELTEAE LVTAEAVRSV WQRILPKVLE VEDSTDFFKS
360 370 380 390 400
GAASVDVVRL VEEVKELCDG LELENEDVYM ASTFGDFIQL LVRKLRGDDE
410 420 430 440 450
EGECSIDYVE MAVNKRTVRM PHQLFIGGEF VDAEGAKTSE TINPTDGSVI
460 470 480 490 500
CQVSLAQVTD VDKAVAAAKD AFENGRWGKI SARDRGRLMY RLADLMEQHQ
510 520 530 540 550
EELATIEALD AGAVYTLALK THVGMSIQTF RYFAGWCDKI QGSTIPINQA
560 570 580 590 600
RPNRNLTLTR KEPVGVCGII IPWNYPLMML SWKTAACLAA GNTVVIKPAQ
610 620 630 640 650
VTPLTALKFA ELTLKAGIPK GVVNVLPGSG SLVGQRLSDH PDVRKIGFTG
660 670 680 690 700
STEVGKHIMK SCAISNVKKV SLELGGKSPL IIFADCDLNK AVQMGMSSVF
710 720 730 740 750
FNKGENCIAA GRLFVEDSIH DEFVRRVVEE VRKMKVGNPL DRDTDHGPQN
760 770 780 790 800
HHAHLVKLME YCQHGVKEGA TLVCGGNQVP RPGFFFEPTV FTDVEDHMFI
810 820 830 840 850
AKEESFGPVM IISRFADGDL DAVLSRANAT EFGLASGVFT RDINKALYVS
860 870 880 890 900
DKLQAGTVFV NTYNKTDVAA PFGGFKQSGF GKDLGEAALN EYLRVKTVTF
EY
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketC9IZ36 | C9IZ36_HUMAN | Cytosolic 10-formyltetrahydrofolate... | ALDH1L1 | 177 | Annotation score: | ||
C9JY00 | C9JY00_HUMAN | Cytosolic 10-formyltetrahydrofolate... | ALDH1L1 | 157 | Annotation score: | ||
C9JYZ6 | C9JYZ6_HUMAN | Cytosolic 10-formyltetrahydrofolate... | ALDH1L1 | 168 | Annotation score: | ||
D6RFJ7 | D6RFJ7_HUMAN | Cytosolic 10-formyltetrahydrofolate... | ALDH1L1 | 100 | Annotation score: | ||
F8WC34 | F8WC34_HUMAN | Cytosolic 10-formyltetrahydrofolate... | ALDH1L1 | 81 | Annotation score: | ||
F2Z324 | F2Z324_HUMAN | Aldehyde dehydrogenase 1 family mem... | ALDH1L1 | 47 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 63 | G → A in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 85 | F → S in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 176 | M → V in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 195 | E → K in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 470 | D → G in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 472 | F → L in BAG57647 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 677 | K → E in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 680 | L → F in AAC35000 (Ref. 1) Curated | 1 | |
Sequence conflicti | 702 | N → S in AAC35000 (Ref. 1) Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_052290 | 254 | L → P. Corresponds to variant dbSNP:rs3796191Ensembl. | 1 | |
Natural variantiVAR_052291 | 330 | V → F. Corresponds to variant dbSNP:rs2886059Ensembl. | 1 | |
Natural variantiVAR_052292 | 429 | E → A. Corresponds to variant dbSNP:rs9282691Ensembl. | 1 | |
Natural variantiVAR_052293 | 436 | A → T. Corresponds to variant dbSNP:rs9282692Ensembl. | 1 | |
Natural variantiVAR_052295 | 448 | S → N. Corresponds to variant dbSNP:rs9282697Ensembl. | 1 | |
Natural variantiVAR_052296 | 481 | S → G. Corresponds to variant dbSNP:rs2276724Ensembl. | 1 | |
Natural variantiVAR_036101 | 511 | A → V in a colorectal cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs768309358Ensembl. | 1 | |
Natural variantiVAR_052297 | 793 | D → G. Corresponds to variant dbSNP:rs1127717Ensembl. | 1 | |
Natural variantiVAR_052298 | 803 | E → K. Corresponds to variant dbSNP:rs9282689Ensembl. | 1 | |
Natural variantiVAR_052299 | 812 | I → V. Corresponds to variant dbSNP:rs4646750Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_047260 | 1 | M → MAGPSNPPATM in isoform 3. 1 Publication | 1 | |
Alternative sequenceiVSP_045569 | 118 – 218 | Missing in isoform 2. 1 PublicationAdd BLAST | 101 | |
Alternative sequenceiVSP_057429 | 492 – 505 | LADLM…EELAT → APPSPSTRPDPTAT in isoform 4. 1 PublicationAdd BLAST | 14 | |
Alternative sequenceiVSP_057430 | 506 – 902 | Missing in isoform 4. 1 PublicationAdd BLAST | 397 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF052732 mRNA Translation: AAC35000.1 AK294392 mRNA Translation: BAG57647.1 CR749807 mRNA Translation: CAH18667.1 AC079848 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW79370.1 BC027241 mRNA Translation: AAH27241.1 |
CCDSi | CCDS3034.1 [O75891-1] CCDS58850.1 [O75891-2] CCDS58851.1 [O75891-3] |
RefSeqi | NP_001257293.1, NM_001270364.1 [O75891-3] NP_001257294.1, NM_001270365.1 [O75891-2] NP_036322.2, NM_012190.3 [O75891-1] XP_006713544.1, XM_006713481.2 [O75891-1] XP_011510657.1, XM_011512355.1 [O75891-1] |
Genome annotation databases
Ensembli | ENST00000273450; ENSP00000273450; ENSG00000144908 [O75891-3] ENST00000393431; ENSP00000377081; ENSG00000144908 [O75891-4] ENST00000393434; ENSP00000377083; ENSG00000144908 [O75891-1] ENST00000452905; ENSP00000395881; ENSG00000144908 [O75891-2] ENST00000455064; ENSP00000414126; ENSG00000144908 [O75891-4] ENST00000472186; ENSP00000420293; ENSG00000144908 [O75891-1] |
GeneIDi | 10840 |
KEGGi | hsa:10840 |
UCSCi | uc003eim.3, human [O75891-1] uc062njt.1, human |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF052732 mRNA Translation: AAC35000.1 AK294392 mRNA Translation: BAG57647.1 CR749807 mRNA Translation: CAH18667.1 AC079848 Genomic DNA No translation available. CH471052 Genomic DNA Translation: EAW79370.1 BC027241 mRNA Translation: AAH27241.1 |
CCDSi | CCDS3034.1 [O75891-1] CCDS58850.1 [O75891-2] CCDS58851.1 [O75891-3] |
RefSeqi | NP_001257293.1, NM_001270364.1 [O75891-3] NP_001257294.1, NM_001270365.1 [O75891-2] NP_036322.2, NM_012190.3 [O75891-1] XP_006713544.1, XM_006713481.2 [O75891-1] XP_011510657.1, XM_011512355.1 [O75891-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2BW0 | X-ray | 1.70 | A | 1-307 | [»] | |
2CFI | X-ray | 1.85 | A | 1-307 | [»] | |
2CQ8 | NMR | - | A | 305-401 | [»] | |
SMRi | O75891 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 116052, 23 interactors |
IntActi | O75891, 77 interactors |
MINTi | O75891 |
STRINGi | 9606.ENSP00000273450 |
Chemistry databases
DrugBanki | DB00116, Tetrahydrofolic acid |
PTM databases
iPTMneti | O75891 |
PhosphoSitePlusi | O75891 |
Polymorphism and mutation databases
BioMutai | ALDH1L1 |
Proteomic databases
EPDi | O75891 |
jPOSTi | O75891 |
MassIVEi | O75891 |
MaxQBi | O75891 |
PaxDbi | O75891 |
PeptideAtlasi | O75891 |
PRIDEi | O75891 |
ProteomicsDBi | 19312 50249 [O75891-1] 74038 |
Protocols and materials databases
ABCDi | O75891, 1 sequenced antibody |
Antibodypediai | 33051, 473 antibodies |
DNASUi | 10840 |
Genome annotation databases
Ensembli | ENST00000273450; ENSP00000273450; ENSG00000144908 [O75891-3] ENST00000393431; ENSP00000377081; ENSG00000144908 [O75891-4] ENST00000393434; ENSP00000377083; ENSG00000144908 [O75891-1] ENST00000452905; ENSP00000395881; ENSG00000144908 [O75891-2] ENST00000455064; ENSP00000414126; ENSG00000144908 [O75891-4] ENST00000472186; ENSP00000420293; ENSG00000144908 [O75891-1] |
GeneIDi | 10840 |
KEGGi | hsa:10840 |
UCSCi | uc003eim.3, human [O75891-1] uc062njt.1, human |
Organism-specific databases
CTDi | 10840 |
DisGeNETi | 10840 |
EuPathDBi | HostDB:ENSG00000144908.13 |
GeneCardsi | ALDH1L1 |
HGNCi | HGNC:3978, ALDH1L1 |
HPAi | ENSG00000144908, Tissue enhanced (kidney, liver) |
MIMi | 600249, gene |
neXtProti | NX_O75891 |
OpenTargetsi | ENSG00000144908 |
PharmGKBi | PA28393 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2452, Eukaryota |
GeneTreei | ENSGT00940000160913 |
HOGENOMi | CLU_014974_1_0_1 |
InParanoidi | O75891 |
OMAi | ENAKINW |
PhylomeDBi | O75891 |
TreeFami | TF354242 |
Enzyme and pathway databases
BioCyci | MetaCyc:HS07217-MONOMER |
BRENDAi | 1.5.1.6, 2681 |
PathwayCommonsi | O75891 |
Reactomei | R-HSA-196757, Metabolism of folate and pterines |
Miscellaneous databases
BioGRID-ORCSi | 10840, 3 hits in 844 CRISPR screens |
ChiTaRSi | ALDH1L1, human |
EvolutionaryTracei | O75891 |
GeneWikii | ALDH1L1 |
GenomeRNAii | 10840 |
Pharosi | O75891, Tbio |
PROi | PR:O75891 |
RNActi | O75891, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000144908, Expressed in liver and 210 other tissues |
ExpressionAtlasi | O75891, baseline and differential |
Genevisiblei | O75891, HS |
Family and domain databases
Gene3Di | 1.10.1200.10, 1 hit 3.10.25.10, 1 hit 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR011407, 10_FTHF_DH IPR036736, ACP-like_sf IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom IPR005793, Formyl_trans_C IPR037022, Formyl_trans_C_sf IPR002376, Formyl_transf_N IPR036477, Formyl_transf_N_sf IPR011034, Formyl_transferase-like_C_sf IPR001555, GART_AS IPR009081, PP-bd_ACP |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit PF02911, Formyl_trans_C, 1 hit PF00551, Formyl_trans_N, 1 hit PF00550, PP-binding, 1 hit |
PIRSFi | PIRSF036489, 10-FTHFDH, 1 hit |
SUPFAMi | SSF47336, SSF47336, 1 hit SSF50486, SSF50486, 1 hit SSF53328, SSF53328, 1 hit SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit PS50075, CARRIER, 1 hit PS00373, GART, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AL1L1_HUMAN | |
Accessioni | O75891Primary (citable) accession number: O75891 Secondary accession number(s): B4DG36 Q8TBP8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | February 15, 2005 | |
Last modified: | December 2, 2020 | |
This is version 199 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations