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Protein
Submitted name:

Killer cell lectin-like receptor subfamily A, member 1

Gene

LY49L

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • carbohydrate binding Source: ProtInc
  • transmembrane signaling receptor activity Source: ProtInc

GO - Biological processi

Keywordsi

Molecular functionReceptorImported
LigandLectinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Killer cell lectin-like receptor subfamily A, member 1Imported
Submitted name:
Killer cell lectin-like receptor subfamily A, member 1, isoform CRA_aImported
Submitted name:
Ly-49LImported
Gene namesi
Name:LY49LImported
Synonyms:KLRA1Imported
ORF Names:hCG_27420Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 70HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

IntActiO75889, 28 interactors
O75889, 28 interactors

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 165Ly49InterPro annotationAdd BLAST125

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG053176

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
IPR013600 Ly49_N
PfamiView protein in Pfam
PF08391 Ly49, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit

Sequencei

Sequence statusi: Complete.

O75889-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDQGEIYST LRFLQSPSES QNRLRPDDTQ RPGKTDDKEF SVPWHLIAVT
60 70 80 90 100
LGILCLLLLM IVTVLVTNIF QCIQEKHQRQ EILRNCSEKY IMQNDNYLKE
110 120 130 140 150
QILTNKTLKY DVLKNSFQQK KELDSRLIQK NRCHRENEIV FKVLQNTGKF
160 170 180 190 200
SEDHGSCCGV NCYYFTMQKK DWKGCKQTCQ HCRSSLLKID DKDELVFYIH
210
FYSLGLCFSM LDLRY
Length:215
Mass (Da):25,457
Last modified:November 1, 1998 - v1
Checksum:i2B0A7CCA5A462C80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF047445 mRNA Translation: AAC35898.1
BC069672 mRNA Translation: AAH69672.1
BC069734 mRNA Translation: AAH69734.1
BC101471 mRNA Translation: AAI01472.1
BC101473 mRNA Translation: AAI01474.1
CH471094 Genomic DNA Translation: EAW96193.1
CH471094 Genomic DNA Translation: EAW96195.1
UniGeneiHs.159297

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF047445 mRNA Translation: AAC35898.1
BC069672 mRNA Translation: AAH69672.1
BC069734 mRNA Translation: AAH69734.1
BC101471 mRNA Translation: AAI01472.1
BC101473 mRNA Translation: AAI01474.1
CH471094 Genomic DNA Translation: EAW96193.1
CH471094 Genomic DNA Translation: EAW96195.1
UniGeneiHs.159297

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO75889, 28 interactors
O75889, 28 interactors

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

H-InvDBiHIX0036687

Phylogenomic databases

HOVERGENiHBG053176

Miscellaneous databases

ChiTaRSiKLRA1P human

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
IPR013600 Ly49_N
PfamiView protein in Pfam
PF08391 Ly49, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO75889_HUMAN
AccessioniPrimary (citable) accession number: O75889
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1998
Last sequence update: November 1, 1998
Last modified: November 7, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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