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UniProtKB - O75832 (PSD10_HUMAN)

Protein

26S proteasome non-ATPase regulatory subunit 10

Gene

PSMD10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome, regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway, leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.
Acts as an proto-oncoprotein by being involved in negative regulation of tumor suppressors RB1 and p53/TP53. Overexpression is leading to phosphorylation of RB1 and proteasomal degradation of RB1. Regulates CDK4-mediated phosphorylation of RB1 by competing with CDKN2A for binding with CDK4. Facilitates binding of MDM2 to p53/TP53 and the mono- and polyubiquitination of p53/TP53 by MDM2 suggesting a function in targeting the TP53:MDM2 complex to the 26S proteasome. Involved in p53-independent apoptosis. Involved in regulation of NF-kappa-B by retaining it in the cytoplasm. Binds to the NF-kappa-B component RELA and accelerates its XPO1/CRM1-mediated nuclear export.

Caution

Was initially identified as a genuine component of the 26S proteasome.Curated

GO - Molecular functioni

  • transcription factor binding Source: UniProtKB
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionChaperone
Biological processApoptosis

Enzyme and pathway databases

ReactomeiR-HSA-1169091 Activation of NF-kappaB in B cells
R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-HSA-1236974 ER-Phagosome pathway
R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes)
R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C
R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1
R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin
R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-HSA-180534 Vpu mediated degradation of CD4
R-HSA-180585 Vif-mediated degradation of APOBEC3G
R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21
R-HSA-195253 Degradation of beta-catenin by the destruction complex
R-HSA-202424 Downstream TCR signaling
R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation
R-HSA-2467813 Separation of Sister Chromatids
R-HSA-2871837 FCERI mediated NF-kB activation
R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1
R-HSA-350562 Regulation of ornithine decarboxylase (ODC)
R-HSA-382556 ABC-family proteins mediated transport
R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA
R-HSA-4608870 Asymmetric localization of PCP proteins
R-HSA-4641257 Degradation of AXIN
R-HSA-4641258 Degradation of DVL
R-HSA-5358346 Hedgehog ligand biogenesis
R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling
R-HSA-5607764 CLEC7A (Dectin-1) signaling
R-HSA-5610780 Degradation of GLI1 by the proteasome
R-HSA-5610783 Degradation of GLI2 by the proteasome
R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome
R-HSA-5632684 Hedgehog 'on' state
R-HSA-5658442 Regulation of RAS by GAPs
R-HSA-5668541 TNFR2 non-canonical NF-kB pathway
R-HSA-5676590 NIK-->noncanonical NF-kB signaling
R-HSA-5678895 Defective CFTR causes cystic fibrosis
R-HSA-5687128 MAPK6/MAPK4 signaling
R-HSA-5689603 UCH proteinases
R-HSA-5689880 Ub-specific processing proteases
R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex
R-HSA-68949 Orc1 removal from chromatin
R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6
R-HSA-69229 Ubiquitin-dependent degradation of Cyclin D1
R-HSA-69481 G2/M Checkpoints
R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint
R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs
R-HSA-8939902 Regulation of RUNX2 expression and activity
R-HSA-8941858 Regulation of RUNX3 expression and activity
R-HSA-8948751 Regulation of PTEN stability and activity
R-HSA-8951664 Neddylation
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-9020702 Interleukin-1 signaling
R-HSA-9604323 Negative regulation of NOTCH4 signaling
R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Recommended name:
26S proteasome non-ATPase regulatory subunit 10
Alternative name(s):
26S proteasome regulatory subunit p28
Gankyrin
p28(GANK)
Gene namesi
Name:PSMD10
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000101843.18
HGNCiHGNC:9555 PSMD10
MIMi300880 gene
neXtProtiNX_O75832

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi182E → A: Abolishes interaction with RB1. 1 Publication1

Organism-specific databases

DisGeNETi5716
OpenTargetsiENSG00000101843
PharmGKBiPA33900

Chemistry databases

ChEMBLiCHEMBL2331054

Polymorphism and mutation databases

BioMutaiPSMD10

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000670451 – 22626S proteasome non-ATPase regulatory subunit 10Add BLAST226

Proteomic databases

EPDiO75832
MaxQBiO75832
PaxDbiO75832
PeptideAtlasiO75832
PRIDEiO75832
ProteomicsDBi50220
50221 [O75832-2]
TopDownProteomicsiO75832-1 [O75832-1]

2D gel databases

OGPiO75832

PTM databases

iPTMnetiO75832
PhosphoSitePlusiO75832

Expressioni

Tissue specificityi

Tends to be up-regulated in cancer cells with RAS mutations, including lung cancers and adenocarconimas (at protein level).2 Publications

Gene expression databases

BgeeiENSG00000101843 Expressed in 228 organ(s), highest expression level in substantia nigra
CleanExiHS_PSMD10
ExpressionAtlasiO75832 baseline and differential
GenevisibleiO75832 HS

Organism-specific databases

HPAiCAB010434
HPA002920

Interactioni

Subunit structurei

Part of transient complex containing PSMD10, PSMC4, PSMC5 and PAAF1 formed during the assembly of the 26S proteasome. Stays associated throughout the assembly of the PA700/19S RC and is released upon association with the 20S core. Interacts with PSMC4. Interacts with RB1. Interacts with CDK4. Interacts with MDM2. Interacts with RELA. Associates with a CDK4:CCND2 serine/threonine kinase complex. Interacts with ARHGDIA and increases the interaction between ARHGDIA and RHOA, hence promotes ARHGDIA inactivation of RHOA and ROCK.7 Publications

Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridi111688, 79 interactors
CORUMiO75832
DIPiDIP-39026N
IntActiO75832, 33 interactors
MINTiO75832
STRINGi9606.ENSP00000217958

Structurei

Secondary structure

1226
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliO75832
SMRiO75832
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO75832

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati3 – 36ANK 1Add BLAST34
Repeati37 – 69ANK 2Add BLAST33
Repeati70 – 102ANK 3Add BLAST33
Repeati103 – 135ANK 4Add BLAST33
Repeati136 – 168ANK 5Add BLAST33
Repeati169 – 201ANK 6Add BLAST33
Repeati202 – 226ANK 7Add BLAST25

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 71Interaction with RB11 PublicationAdd BLAST71
Regioni1 – 37Required for nuclear localizationAdd BLAST37
Regioni39 – 226Interaction with RELAAdd BLAST188
Regioni171 – 226Interaction with RB11 PublicationAdd BLAST56

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiKOG4412 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00930000150856
HOGENOMiHOG000158359
HOVERGENiHBG053737
InParanoidiO75832
KOiK06694
OMAiSVNQNGC
OrthoDBiEOG091G0KEZ
PhylomeDBiO75832
TreeFamiTF106234

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR039334 PSMD10_like
PANTHERiPTHR44187 PTHR44187, 1 hit
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 2 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O75832-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA 
        60         70         80         90        100
GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN 
       110        120        130        140        150
AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG 
       160        170        180        190        200
NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI 
       210        220 
ENKEEKTPLQ VAKGGLGLIL KRMVEG
Length:226
Mass (Da):24,428
Last modified:November 1, 1998 - v1
Checksum:i57158E33146EC7C8
GO
Isoform 2 (identifier: O75832-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     150-226: GNLKMIHILL...GLILKRMVEG → DT

Show »
Length:151
Mass (Da):16,137
Checksum:iBEA968FE1439F3CC
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AJY5B1AJY5_HUMAN
26S proteasome non-ATPase regulator...
PSMD10
185Annotation score:
B1AJY7B1AJY7_HUMAN
26S proteasome non-ATPase regulator...
PSMD10
193Annotation score:
B1AJY6B1AJY6_HUMAN
26S proteasome non-ATPase regulator...
PSMD10
110Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti196A → T in AAV38495 (Ref. 5) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_043043150 – 226GNLKM…RMVEG → DT in isoform 2. 2 PublicationsAdd BLAST77

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009619 mRNA Translation: BAA33215.1
D83197 mRNA Translation: BAA34594.1
AY057056 mRNA Translation: AAL25260.1
AK295996 mRNA Translation: BAG58771.1
BT019689 mRNA Translation: AAV38495.1
AL031177 Genomic DNA No translation available.
BC011960 mRNA Translation: AAH11960.1
CCDSiCCDS14536.1 [O75832-1]
CCDS14537.1 [O75832-2]
RefSeqiNP_002805.1, NM_002814.3 [O75832-1]
NP_736606.1, NM_170750.2 [O75832-2]
UniGeneiHs.522752

Genome annotation databases

EnsembliENST00000217958; ENSP00000217958; ENSG00000101843 [O75832-1]
ENST00000361815; ENSP00000354906; ENSG00000101843 [O75832-2]
GeneIDi5716
KEGGihsa:5716
UCSCiuc004enp.3 human [O75832-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB009619 mRNA Translation: BAA33215.1
D83197 mRNA Translation: BAA34594.1
AY057056 mRNA Translation: AAL25260.1
AK295996 mRNA Translation: BAG58771.1
BT019689 mRNA Translation: AAV38495.1
AL031177 Genomic DNA No translation available.
BC011960 mRNA Translation: AAH11960.1
CCDSiCCDS14536.1 [O75832-1]
CCDS14537.1 [O75832-2]
RefSeqiNP_002805.1, NM_002814.3 [O75832-1]
NP_736606.1, NM_170750.2 [O75832-2]
UniGeneiHs.522752

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QYMX-ray2.80A2-226[»]
1TR4NMR-A1-226[»]
1UOHX-ray2.00A1-226[»]
4NIKX-ray2.50A1-226[»]
5VHFelectron microscopy5.70G4-226[»]
5VHHelectron microscopy6.10G4-226[»]
5VHIelectron microscopy6.80G1-226[»]
5VHJelectron microscopy8.50G4-226[»]
5VHMelectron microscopy8.30G4-226[»]
5VHNelectron microscopy7.30G4-226[»]
5VHOelectron microscopy8.30G4-226[»]
5VHPelectron microscopy7.90G3-226[»]
5VHQelectron microscopy8.90G4-226[»]
5VHRelectron microscopy7.70G4-226[»]
ProteinModelPortaliO75832
SMRiO75832
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi111688, 79 interactors
CORUMiO75832
DIPiDIP-39026N
IntActiO75832, 33 interactors
MINTiO75832
STRINGi9606.ENSP00000217958

Chemistry databases

ChEMBLiCHEMBL2331054

PTM databases

iPTMnetiO75832
PhosphoSitePlusiO75832

Polymorphism and mutation databases

BioMutaiPSMD10

2D gel databases

OGPiO75832

Proteomic databases

EPDiO75832
MaxQBiO75832
PaxDbiO75832
PeptideAtlasiO75832
PRIDEiO75832
ProteomicsDBi50220
50221 [O75832-2]
TopDownProteomicsiO75832-1 [O75832-1]

Protocols and materials databases

DNASUi5716
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000217958; ENSP00000217958; ENSG00000101843 [O75832-1]
ENST00000361815; ENSP00000354906; ENSG00000101843 [O75832-2]
GeneIDi5716
KEGGihsa:5716
UCSCiuc004enp.3 human [O75832-1]

Organism-specific databases

CTDi5716
DisGeNETi5716
EuPathDBiHostDB:ENSG00000101843.18
GeneCardsiPSMD10
HGNCiHGNC:9555 PSMD10
HPAiCAB010434
HPA002920
MIMi300880 gene
neXtProtiNX_O75832
OpenTargetsiENSG00000101843
PharmGKBiPA33900
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4412 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00930000150856
HOGENOMiHOG000158359
HOVERGENiHBG053737
InParanoidiO75832
KOiK06694
OMAiSVNQNGC
OrthoDBiEOG091G0KEZ
PhylomeDBiO75832
TreeFamiTF106234

Enzyme and pathway databases

ReactomeiR-HSA-1169091 Activation of NF-kappaB in B cells
R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
R-HSA-1236974 ER-Phagosome pathway
R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes)
R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C
R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1
R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin
R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-HSA-180534 Vpu mediated degradation of CD4
R-HSA-180585 Vif-mediated degradation of APOBEC3G
R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21
R-HSA-195253 Degradation of beta-catenin by the destruction complex
R-HSA-202424 Downstream TCR signaling
R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation
R-HSA-2467813 Separation of Sister Chromatids
R-HSA-2871837 FCERI mediated NF-kB activation
R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1
R-HSA-350562 Regulation of ornithine decarboxylase (ODC)
R-HSA-382556 ABC-family proteins mediated transport
R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA
R-HSA-4608870 Asymmetric localization of PCP proteins
R-HSA-4641257 Degradation of AXIN
R-HSA-4641258 Degradation of DVL
R-HSA-5358346 Hedgehog ligand biogenesis
R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD
R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling
R-HSA-5607764 CLEC7A (Dectin-1) signaling
R-HSA-5610780 Degradation of GLI1 by the proteasome
R-HSA-5610783 Degradation of GLI2 by the proteasome
R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome
R-HSA-5632684 Hedgehog 'on' state
R-HSA-5658442 Regulation of RAS by GAPs
R-HSA-5668541 TNFR2 non-canonical NF-kB pathway
R-HSA-5676590 NIK-->noncanonical NF-kB signaling
R-HSA-5678895 Defective CFTR causes cystic fibrosis
R-HSA-5687128 MAPK6/MAPK4 signaling
R-HSA-5689603 UCH proteinases
R-HSA-5689880 Ub-specific processing proteases
R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex
R-HSA-68949 Orc1 removal from chromatin
R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6
R-HSA-69229 Ubiquitin-dependent degradation of Cyclin D1
R-HSA-69481 G2/M Checkpoints
R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint
R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs
R-HSA-8939902 Regulation of RUNX2 expression and activity
R-HSA-8941858 Regulation of RUNX3 expression and activity
R-HSA-8948751 Regulation of PTEN stability and activity
R-HSA-8951664 Neddylation
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-9020702 Interleukin-1 signaling
R-HSA-9604323 Negative regulation of NOTCH4 signaling
R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

ChiTaRSiPSMD10 human
EvolutionaryTraceiO75832
GeneWikiiPSMD10
GenomeRNAii5716
PROiPR:O75832
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000101843 Expressed in 228 organ(s), highest expression level in substantia nigra
CleanExiHS_PSMD10
ExpressionAtlasiO75832 baseline and differential
GenevisibleiO75832 HS

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR039334 PSMD10_like
PANTHERiPTHR44187 PTHR44187, 1 hit
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 2 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 5 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiPSD10_HUMAN
AccessioniPrimary (citable) accession number: O75832
Secondary accession number(s): Q5U0B2, Q8IZK9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: November 1, 1998
Last modified: November 7, 2018
This is version 186 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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