UniProtKB - O75832 (PSD10_HUMAN)
26S proteasome non-ATPase regulatory subunit 10
PSMD10
Functioni
Caution
GO - Molecular functioni
- transcription factor binding Source: UniProtKB
GO - Biological processi
- anaphase-promoting complex-dependent catabolic process Source: Reactome
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Source: Reactome
- apoptotic process Source: UniProtKB-KW
- cytoplasmic sequestering of NF-kappaB Source: UniProtKB
- Fc-epsilon receptor signaling pathway Source: Reactome
- interleukin-1-mediated signaling pathway Source: Reactome
- MAPK cascade Source: Reactome
- negative regulation of apoptotic process Source: UniProtKB
- negative regulation of canonical Wnt signaling pathway Source: Reactome
- negative regulation of DNA damage response, signal transduction by p53 class mediator Source: UniProtKB
- negative regulation of G2/M transition of mitotic cell cycle Source: Reactome
- negative regulation of MAPK cascade Source: UniProtKB
- negative regulation of NF-kappaB transcription factor activity Source: UniProtKB
- negative regulation of release of cytochrome c from mitochondria Source: UniProtKB
- negative regulation of transcription by RNA polymerase II Source: UniProtKB
- NIK/NF-kappaB signaling Source: Reactome
- positive regulation of canonical Wnt signaling pathway Source: Reactome
- positive regulation of cell growth Source: UniProtKB
- positive regulation of cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: UniProtKB
- positive regulation of protein ubiquitination Source: UniProtKB
- post-translational protein modification Source: Reactome
- proteasome-mediated ubiquitin-dependent protein catabolic process Source: Reactome
- proteasome regulatory particle assembly Source: UniProtKB
- protein deubiquitination Source: Reactome
- protein polyubiquitination Source: Reactome
- regulation of cellular amino acid metabolic process Source: Reactome
- regulation of hematopoietic stem cell differentiation Source: Reactome
- regulation of mitotic cell cycle phase transition Source: Reactome
- regulation of mRNA stability Source: Reactome
- regulation of transcription from RNA polymerase II promoter in response to hypoxia Source: Reactome
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: Reactome
- stimulatory C-type lectin receptor signaling pathway Source: Reactome
- T cell receptor signaling pathway Source: Reactome
- transmembrane transport Source: Reactome
- tumor necrosis factor-mediated signaling pathway Source: Reactome
- Wnt signaling pathway, planar cell polarity pathway Source: Reactome
Keywordsi
Molecular function | Chaperone |
Biological process | Apoptosis |
Enzyme and pathway databases
PathwayCommonsi | O75832 |
Reactomei | R-HSA-1169091, Activation of NF-kappaB in B cells R-HSA-1234176, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1236974, ER-Phagosome pathway R-HSA-1236978, Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-174084, Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174113, SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174154, APC/C:Cdc20 mediated degradation of Securin R-HSA-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-180534, Vpu mediated degradation of CD4 R-HSA-180585, Vif-mediated degradation of APOBEC3G R-HSA-187577, SCF(Skp2)-mediated degradation of p27/p21 R-HSA-195253, Degradation of beta-catenin by the destruction complex R-HSA-202424, Downstream TCR signaling R-HSA-211733, Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2871837, FCERI mediated NF-kB activation R-HSA-349425, Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-350562, Regulation of ornithine decarboxylase (ODC) R-HSA-382556, ABC-family proteins mediated transport R-HSA-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-4608870, Asymmetric localization of PCP proteins R-HSA-4641257, Degradation of AXIN R-HSA-4641258, Degradation of DVL R-HSA-5358346, Hedgehog ligand biogenesis R-HSA-5362768, Hh mutants that don't undergo autocatalytic processing are degraded by ERAD R-HSA-5607761, Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607764, CLEC7A (Dectin-1) signaling R-HSA-5610780, Degradation of GLI1 by the proteasome R-HSA-5610783, Degradation of GLI2 by the proteasome R-HSA-5610785, GLI3 is processed to GLI3R by the proteasome R-HSA-5632684, Hedgehog 'on' state R-HSA-5658442, Regulation of RAS by GAPs R-HSA-5668541, TNFR2 non-canonical NF-kB pathway R-HSA-5676590, NIK-->noncanonical NF-kB signaling R-HSA-5678895, Defective CFTR causes cystic fibrosis R-HSA-5687128, MAPK6/MAPK4 signaling R-HSA-5689603, UCH proteinases R-HSA-5689880, Ub-specific processing proteases R-HSA-68827, CDT1 association with the CDC6:ORC:origin complex R-HSA-68949, Orc1 removal from chromatin R-HSA-69017, CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69481, G2/M Checkpoints R-HSA-69601, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-75815, Ubiquitin-dependent degradation of Cyclin D R-HSA-8852276, The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8854050, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939902, Regulation of RUNX2 expression and activity R-HSA-8941858, Regulation of RUNX3 expression and activity R-HSA-8948751, Regulation of PTEN stability and activity R-HSA-8951664, Neddylation R-HSA-9010553, Regulation of expression of SLITs and ROBOs R-HSA-9020702, Interleukin-1 signaling R-HSA-9604323, Negative regulation of NOTCH4 signaling R-HSA-983168, Antigen processing: Ubiquitination & Proteasome degradation |
Names & Taxonomyi
Protein namesi | Recommended name: 26S proteasome non-ATPase regulatory subunit 10Alternative name(s): 26S proteasome regulatory subunit p28 Gankyrin p28(GANK) |
Gene namesi | Name:PSMD10 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9555, PSMD10 |
MIMi | 300880, gene |
neXtProti | NX_O75832 |
VEuPathDBi | HostDB:ENSG00000101843.18 |
Subcellular locationi
Cytoskeleton
- intermediate filament cytoskeleton Source: HPA
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: Reactome
- nucleus Source: UniProtKB
Other locations
- cytoplasm Source: UniProtKB
- proteasome complex Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 182 | E → A: Abolishes interaction with RB1. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 5716 |
OpenTargetsi | ENSG00000101843 |
PharmGKBi | PA33900 |
Miscellaneous databases
Pharosi | O75832, Tbio |
Chemistry databases
ChEMBLi | CHEMBL2331054 |
Genetic variation databases
BioMutai | PSMD10 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000067045 | 1 – 226 | 26S proteasome non-ATPase regulatory subunit 10Add BLAST | 226 |
Proteomic databases
EPDi | O75832 |
jPOSTi | O75832 |
MassIVEi | O75832 |
MaxQBi | O75832 |
PaxDbi | O75832 |
PeptideAtlasi | O75832 |
PRIDEi | O75832 |
ProteomicsDBi | 50220 [O75832-1] 50221 [O75832-2] |
TopDownProteomicsi | O75832-1 [O75832-1] |
2D gel databases
OGPi | O75832 |
PTM databases
iPTMneti | O75832 |
MetOSitei | O75832 |
PhosphoSitePlusi | O75832 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000101843, Expressed in substantia nigra and 242 other tissues |
ExpressionAtlasi | O75832, baseline and differential |
Genevisiblei | O75832, HS |
Organism-specific databases
HPAi | ENSG00000101843, Low tissue specificity |
Interactioni
Subunit structurei
Part of transient complex containing PSMD10, PSMC4, PSMC5 and PAAF1 formed during the assembly of the 26S proteasome. Stays associated throughout the assembly of the PA700/19S RC and is released upon association with the 20S core.
Interacts with PSMC4.
Interacts with RB1.
Interacts with CDK4.
Interacts with MDM2.
Interacts with RELA. Associates with a CDK4:CCND2 serine/threonine kinase complex.
Interacts with ARHGDIA and increases the interaction between ARHGDIA and RHOA, hence promotes ARHGDIA inactivation of RHOA and ROCK.
7 PublicationsBinary interactionsi
Hide detailsO75832
GO - Molecular functioni
- transcription factor binding Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 111688, 91 interactors |
CORUMi | O75832 |
DIPi | DIP-39026N |
IntActi | O75832, 39 interactors |
MINTi | O75832 |
STRINGi | 9606.ENSP00000217958 |
Miscellaneous databases
RNActi | O75832, protein |
Structurei
Secondary structure
3D structure databases
BMRBi | O75832 |
SMRi | O75832 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | O75832 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 3 – 36 | ANK 1Add BLAST | 34 | |
Repeati | 37 – 69 | ANK 2Add BLAST | 33 | |
Repeati | 70 – 102 | ANK 3Add BLAST | 33 | |
Repeati | 103 – 135 | ANK 4Add BLAST | 33 | |
Repeati | 136 – 168 | ANK 5Add BLAST | 33 | |
Repeati | 169 – 201 | ANK 6Add BLAST | 33 | |
Repeati | 202 – 226 | ANK 7Add BLAST | 25 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 71 | Interaction with RB11 PublicationAdd BLAST | 71 | |
Regioni | 1 – 37 | Required for nuclear localizationAdd BLAST | 37 | |
Regioni | 39 – 226 | Interaction with RELAAdd BLAST | 188 | |
Regioni | 171 – 226 | Interaction with RB11 PublicationAdd BLAST | 56 |
Keywords - Domaini
ANK repeat, RepeatPhylogenomic databases
eggNOGi | KOG4412, Eukaryota |
GeneTreei | ENSGT00940000153404 |
HOGENOMi | CLU_000134_18_2_1 |
InParanoidi | O75832 |
OMAi | NLKMIQI |
OrthoDBi | 1514637at2759 |
PhylomeDBi | O75832 |
TreeFami | TF106234 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR039334, PSMD10-like |
PANTHERi | PTHR24126:SF24, PTHR24126:SF24, 1 hit |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 5 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 5 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA
60 70 80 90 100
GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN
110 120 130 140 150
AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG
160 170 180 190 200
NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI
210 220
ENKEEKTPLQ VAKGGLGLIL KRMVEG
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketB1AJY5 | B1AJY5_HUMAN | 26S proteasome non-ATPase regulator... | PSMD10 | 185 | Annotation score: | ||
B1AJY7 | B1AJY7_HUMAN | 26S proteasome non-ATPase regulator... | PSMD10 | 193 | Annotation score: | ||
B1AJY6 | B1AJY6_HUMAN | 26S proteasome non-ATPase regulator... | PSMD10 | 110 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 196 | A → T in AAV38495 (Ref. 5) Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_043043 | 150 – 226 | GNLKM…RMVEG → DT in isoform 2. 2 PublicationsAdd BLAST | 77 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB009619 mRNA Translation: BAA33215.1 D83197 mRNA Translation: BAA34594.1 AY057056 mRNA Translation: AAL25260.1 AK295996 mRNA Translation: BAG58771.1 BT019689 mRNA Translation: AAV38495.1 AL031177 Genomic DNA No translation available. BC011960 mRNA Translation: AAH11960.1 |
CCDSi | CCDS14536.1 [O75832-1] CCDS14537.1 [O75832-2] |
RefSeqi | NP_002805.1, NM_002814.3 [O75832-1] NP_736606.1, NM_170750.2 [O75832-2] |
Genome annotation databases
Ensembli | ENST00000217958; ENSP00000217958; ENSG00000101843 [O75832-1] ENST00000361815; ENSP00000354906; ENSG00000101843 [O75832-2] |
GeneIDi | 5716 |
KEGGi | hsa:5716 |
UCSCi | uc004enp.3, human [O75832-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB009619 mRNA Translation: BAA33215.1 D83197 mRNA Translation: BAA34594.1 AY057056 mRNA Translation: AAL25260.1 AK295996 mRNA Translation: BAG58771.1 BT019689 mRNA Translation: AAV38495.1 AL031177 Genomic DNA No translation available. BC011960 mRNA Translation: AAH11960.1 |
CCDSi | CCDS14536.1 [O75832-1] CCDS14537.1 [O75832-2] |
RefSeqi | NP_002805.1, NM_002814.3 [O75832-1] NP_736606.1, NM_170750.2 [O75832-2] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1QYM | X-ray | 2.80 | A | 2-226 | [»] | |
1TR4 | NMR | - | A | 1-226 | [»] | |
1UOH | X-ray | 2.00 | A | 1-226 | [»] | |
4NIK | X-ray | 2.50 | A | 1-226 | [»] | |
5VHF | electron microscopy | 5.70 | G | 4-226 | [»] | |
5VHH | electron microscopy | 6.10 | G | 4-226 | [»] | |
5VHI | electron microscopy | 6.80 | G | 1-226 | [»] | |
5VHJ | electron microscopy | 8.50 | G | 4-226 | [»] | |
5VHM | electron microscopy | 8.30 | G | 4-226 | [»] | |
5VHN | electron microscopy | 7.30 | G | 4-226 | [»] | |
5VHO | electron microscopy | 8.30 | G | 4-226 | [»] | |
5VHP | electron microscopy | 7.90 | G | 3-226 | [»] | |
5VHQ | electron microscopy | 8.90 | G | 4-226 | [»] | |
5VHR | electron microscopy | 7.70 | G | 4-226 | [»] | |
BMRBi | O75832 | |||||
SMRi | O75832 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 111688, 91 interactors |
CORUMi | O75832 |
DIPi | DIP-39026N |
IntActi | O75832, 39 interactors |
MINTi | O75832 |
STRINGi | 9606.ENSP00000217958 |
Chemistry databases
ChEMBLi | CHEMBL2331054 |
PTM databases
iPTMneti | O75832 |
MetOSitei | O75832 |
PhosphoSitePlusi | O75832 |
Genetic variation databases
BioMutai | PSMD10 |
2D gel databases
OGPi | O75832 |
Proteomic databases
EPDi | O75832 |
jPOSTi | O75832 |
MassIVEi | O75832 |
MaxQBi | O75832 |
PaxDbi | O75832 |
PeptideAtlasi | O75832 |
PRIDEi | O75832 |
ProteomicsDBi | 50220 [O75832-1] 50221 [O75832-2] |
TopDownProteomicsi | O75832-1 [O75832-1] |
Protocols and materials databases
ABCDi | O75832, 1 sequenced antibody |
Antibodypediai | 496, 421 antibodies |
DNASUi | 5716 |
Genome annotation databases
Ensembli | ENST00000217958; ENSP00000217958; ENSG00000101843 [O75832-1] ENST00000361815; ENSP00000354906; ENSG00000101843 [O75832-2] |
GeneIDi | 5716 |
KEGGi | hsa:5716 |
UCSCi | uc004enp.3, human [O75832-1] |
Organism-specific databases
CTDi | 5716 |
DisGeNETi | 5716 |
GeneCardsi | PSMD10 |
HGNCi | HGNC:9555, PSMD10 |
HPAi | ENSG00000101843, Low tissue specificity |
MIMi | 300880, gene |
neXtProti | NX_O75832 |
OpenTargetsi | ENSG00000101843 |
PharmGKBi | PA33900 |
VEuPathDBi | HostDB:ENSG00000101843.18 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG4412, Eukaryota |
GeneTreei | ENSGT00940000153404 |
HOGENOMi | CLU_000134_18_2_1 |
InParanoidi | O75832 |
OMAi | NLKMIQI |
OrthoDBi | 1514637at2759 |
PhylomeDBi | O75832 |
TreeFami | TF106234 |
Enzyme and pathway databases
PathwayCommonsi | O75832 |
Reactomei | R-HSA-1169091, Activation of NF-kappaB in B cells R-HSA-1234176, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha R-HSA-1236974, ER-Phagosome pathway R-HSA-1236978, Cross-presentation of soluble exogenous antigens (endosomes) R-HSA-174084, Autodegradation of Cdh1 by Cdh1:APC/C R-HSA-174113, SCF-beta-TrCP mediated degradation of Emi1 R-HSA-174154, APC/C:Cdc20 mediated degradation of Securin R-HSA-174178, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 R-HSA-174184, Cdc20:Phospho-APC/C mediated degradation of Cyclin A R-HSA-180534, Vpu mediated degradation of CD4 R-HSA-180585, Vif-mediated degradation of APOBEC3G R-HSA-187577, SCF(Skp2)-mediated degradation of p27/p21 R-HSA-195253, Degradation of beta-catenin by the destruction complex R-HSA-202424, Downstream TCR signaling R-HSA-211733, Regulation of activated PAK-2p34 by proteasome mediated degradation R-HSA-2467813, Separation of Sister Chromatids R-HSA-2871837, FCERI mediated NF-kB activation R-HSA-349425, Autodegradation of the E3 ubiquitin ligase COP1 R-HSA-350562, Regulation of ornithine decarboxylase (ODC) R-HSA-382556, ABC-family proteins mediated transport R-HSA-450408, AUF1 (hnRNP D0) binds and destabilizes mRNA R-HSA-4608870, Asymmetric localization of PCP proteins R-HSA-4641257, Degradation of AXIN R-HSA-4641258, Degradation of DVL R-HSA-5358346, Hedgehog ligand biogenesis R-HSA-5362768, Hh mutants that don't undergo autocatalytic processing are degraded by ERAD R-HSA-5607761, Dectin-1 mediated noncanonical NF-kB signaling R-HSA-5607764, CLEC7A (Dectin-1) signaling R-HSA-5610780, Degradation of GLI1 by the proteasome R-HSA-5610783, Degradation of GLI2 by the proteasome R-HSA-5610785, GLI3 is processed to GLI3R by the proteasome R-HSA-5632684, Hedgehog 'on' state R-HSA-5658442, Regulation of RAS by GAPs R-HSA-5668541, TNFR2 non-canonical NF-kB pathway R-HSA-5676590, NIK-->noncanonical NF-kB signaling R-HSA-5678895, Defective CFTR causes cystic fibrosis R-HSA-5687128, MAPK6/MAPK4 signaling R-HSA-5689603, UCH proteinases R-HSA-5689880, Ub-specific processing proteases R-HSA-68827, CDT1 association with the CDC6:ORC:origin complex R-HSA-68949, Orc1 removal from chromatin R-HSA-69017, CDK-mediated phosphorylation and removal of Cdc6 R-HSA-69481, G2/M Checkpoints R-HSA-69601, Ubiquitin Mediated Degradation of Phosphorylated Cdc25A R-HSA-75815, Ubiquitin-dependent degradation of Cyclin D R-HSA-8852276, The role of GTSE1 in G2/M progression after G2 checkpoint R-HSA-8854050, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis R-HSA-8939236, RUNX1 regulates transcription of genes involved in differentiation of HSCs R-HSA-8939902, Regulation of RUNX2 expression and activity R-HSA-8941858, Regulation of RUNX3 expression and activity R-HSA-8948751, Regulation of PTEN stability and activity R-HSA-8951664, Neddylation R-HSA-9010553, Regulation of expression of SLITs and ROBOs R-HSA-9020702, Interleukin-1 signaling R-HSA-9604323, Negative regulation of NOTCH4 signaling R-HSA-983168, Antigen processing: Ubiquitination & Proteasome degradation |
Miscellaneous databases
BioGRID-ORCSi | 5716, 9 hits in 500 CRISPR screens |
ChiTaRSi | PSMD10, human |
EvolutionaryTracei | O75832 |
GeneWikii | PSMD10 |
GenomeRNAii | 5716 |
Pharosi | O75832, Tbio |
PROi | PR:O75832 |
RNActi | O75832, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000101843, Expressed in substantia nigra and 242 other tissues |
ExpressionAtlasi | O75832, baseline and differential |
Genevisiblei | O75832, HS |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR039334, PSMD10-like |
PANTHERi | PTHR24126:SF24, PTHR24126:SF24, 1 hit |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 5 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 5 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PSD10_HUMAN | |
Accessioni | O75832Primary (citable) accession number: O75832 Secondary accession number(s): Q5U0B2, Q8IZK9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 10, 2002 |
Last sequence update: | November 1, 1998 | |
Last modified: | February 10, 2021 | |
This is version 202 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome X
Human chromosome X: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references