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UniProtKB - O75541 (ZN821_HUMAN)

Entry version 174 (02 Dec 2020)
Sequence version 3 (16 May 2012)
Previous versions | rss
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Protein

Zinc finger protein 821

Gene

ZNF821

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri116 – 140C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri150 – 172C2H2-type 2PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O75541

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 821
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF821
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000102984.14

Human Gene Nomenclature Database

More...HGNCi		HGNC:28043, ZNF821

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O75541

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		55565

Open Targets

More...OpenTargetsi		ENSG00000102984

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162410689

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O75541, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF821

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003172891 – 412Zinc finger protein 821Add BLAST412

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O75541

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O75541

PeptideAtlas

More...PeptideAtlasi		O75541

PRoteomics IDEntifications database

More...PRIDEi		O75541

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		50075 [O75541-1]
50076 [O75541-2]

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		O75541, 1 site, 2 N-linked glycans (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O75541

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O75541

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000102984, Expressed in cortical plate and 145 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O75541, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O75541, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000102984, Tissue enhanced (brain, testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		120720, 7 interactors

Protein interaction database and analysis system

More...IntActi		O75541, 7 interactors

Molecular INTeraction database

More...MINTi		O75541

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000398089

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O75541, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili257 – 366Sequence analysisAdd BLAST110

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri116 – 140C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri150 – 172C2H2-type 2PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159421

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O75541

Identification of Orthologs from Complete Genome Data

More...OMAi		NPPVYPA

Database of Orthologous Groups

More...OrthoDBi		901424at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O75541

TreeFam database of animal gene trees

More...TreeFami		TF326851

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 2 hits
PS50157, ZINC_FINGER_C2H2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 10 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O75541-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSRRKQTNPN KVHWDQVFAG LEEQARQAMM KTDFPGDLGS QRQAIQQLRD 
        60         70         80         90        100
QDSSSSDSEG DEEETTQDEV SSHTSEEDGG VVKVEKELEN TEQPVGGNEV 
       110        120        130        140        150
VEHEVTGNLN SDPLLELCQC PLCQLDCGSR EQLIAHVYQH TAAVVSAKSY 
       160        170        180        190        200
MCPVCGRALS SPGSLGRHLL IHSEDQRSNC AVCGARFTSH ATFNSEKLPE 
       210        220        230        240        250
VLNMESLPTV HNEGPSSAEG KDIAFSPPVY PAGILLVCNN CAAYRKLLEA 
       260        270        280        290        300
QTPSVRKWAL RRQNEPLEVR LQRLERERTA KKSRRDNETP EEREVRRMRD 
       310        320        330        340        350
REAKRLQRMQ ETDEQRARRL QRDREAMRLK RANETPEKRQ ARLIREREAK 
       360        370        380        390        400
RLKRRLEKMD MMLRAQFGQD PSAMAALAAE MNFFQLPVSG VELDSQLLGK 
       410 
MAFEEQNSSS LH
Length:412
Mass (Da):46,794
Last modified:May 16, 2012 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB3C953147F1C4E5C
GO
Isoform 2 (identifier: O75541-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     16-57: Missing.

Show »
Length:370
Mass (Da):42,140
Checksum:i383D2D7EFAC1BEB5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0C4DH12A0A0C4DH12_HUMAN
Zinc finger protein 821
ZNF821
370Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BS68H3BS68_HUMAN
Zinc finger protein 821
ZNF821
403Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BPS7H3BPS7_HUMAN
Zinc finger protein 821
ZNF821 LOC55565, hCG_33012
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WXX1A0A087WXX1_HUMAN
Zinc finger protein 821
ZNF821
139Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BVG7H3BVG7_HUMAN
Zinc finger protein 821
ZNF821
212Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BRD6H3BRD6_HUMAN
Zinc finger protein 821
ZNF821
250Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQE4H3BQE4_HUMAN
Zinc finger protein 821
ZNF821
138Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BR75H3BR75_HUMAN
Zinc finger protein 821
ZNF821
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BR59H3BR59_HUMAN
Zinc finger protein 821
ZNF821 LOC55565, hCG_33012
66Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTZ4H3BTZ4_HUMAN
Zinc finger protein 821
ZNF821
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03093316 – 57Missing in isoform 2. 2 PublicationsAdd BLAST42

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF070588 mRNA Translation: AAC28648.1
AK296603 mRNA Translation: BAG59216.1
AC009127 Genomic DNA No translation available.
AC010653 Genomic DNA No translation available.
CH471166 Genomic DNA Translation: EAW59211.1
CH471166 Genomic DNA Translation: EAW59213.1
CH471166 Genomic DNA Translation: EAW59214.1
CH471166 Genomic DNA Translation: EAW59219.1
BC012116 mRNA Translation: AAH12116.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32481.1 [O75541-2]
CCDS56006.1 [O75541-1]

NCBI Reference Sequences

More...RefSeqi		NP_001188481.1, NM_001201552.1 [O75541-1]
NP_001188482.1, NM_001201553.1 [O75541-1]
NP_001188483.1, NM_001201554.1
NP_001188485.1, NM_001201556.1
NP_060000.1, NM_017530.2
XP_005256090.1, XM_005256033.2
XP_006721296.1, XM_006721233.1
XP_011521513.1, XM_011523211.2 [O75541-1]
XP_016878898.1, XM_017023409.1
XP_016878899.1, XM_017023410.1 [O75541-1]
XP_016878900.1, XM_017023411.1 [O75541-1]
XP_016878901.1, XM_017023412.1 [O75541-1]
XP_016878903.1, XM_017023414.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000425432; ENSP00000398089; ENSG00000102984 [O75541-1]
ENST00000565601; ENSP00000455648; ENSG00000102984 [O75541-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		55565

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:55565

UCSC genome browser

More...UCSCi		uc002fbf.4, human [O75541-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF070588 mRNA Translation: AAC28648.1
AK296603 mRNA Translation: BAG59216.1
AC009127 Genomic DNA No translation available.
AC010653 Genomic DNA No translation available.
CH471166 Genomic DNA Translation: EAW59211.1
CH471166 Genomic DNA Translation: EAW59213.1
CH471166 Genomic DNA Translation: EAW59214.1
CH471166 Genomic DNA Translation: EAW59219.1
BC012116 mRNA Translation: AAH12116.1
CCDSiCCDS32481.1 [O75541-2]
CCDS56006.1 [O75541-1]
RefSeqiNP_001188481.1, NM_001201552.1 [O75541-1]
NP_001188482.1, NM_001201553.1 [O75541-1]
NP_001188483.1, NM_001201554.1
NP_001188485.1, NM_001201556.1
NP_060000.1, NM_017530.2
XP_005256090.1, XM_005256033.2
XP_006721296.1, XM_006721233.1
XP_011521513.1, XM_011523211.2 [O75541-1]
XP_016878898.1, XM_017023409.1
XP_016878899.1, XM_017023410.1 [O75541-1]
XP_016878900.1, XM_017023411.1 [O75541-1]
XP_016878901.1, XM_017023412.1 [O75541-1]
XP_016878903.1, XM_017023414.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi120720, 7 interactors
IntActiO75541, 7 interactors
MINTiO75541
STRINGi9606.ENSP00000398089

PTM databases

GlyGeniO75541, 1 site, 2 N-linked glycans (1 site)
iPTMnetiO75541
PhosphoSitePlusiO75541

Polymorphism and mutation databases

BioMutaiZNF821

Proteomic databases

MassIVEiO75541
PaxDbiO75541
PeptideAtlasiO75541
PRIDEiO75541
ProteomicsDBi50075 [O75541-1]
50076 [O75541-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		16662, 91 antibodies

The DNASU plasmid repository

More...DNASUi		55565

Genome annotation databases

EnsembliENST00000425432; ENSP00000398089; ENSG00000102984 [O75541-1]
ENST00000565601; ENSP00000455648; ENSG00000102984 [O75541-1]
GeneIDi55565
KEGGihsa:55565
UCSCiuc002fbf.4, human [O75541-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		55565
DisGeNETi55565
EuPathDBiHostDB:ENSG00000102984.14

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF821
HGNCiHGNC:28043, ZNF821
HPAiENSG00000102984, Tissue enhanced (brain, testis)
neXtProtiNX_O75541
OpenTargetsiENSG00000102984
PharmGKBiPA162410689

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000159421
InParanoidiO75541
OMAiNPPVYPA
OrthoDBi901424at2759
PhylomeDBiO75541
TreeFamiTF326851

Enzyme and pathway databases

PathwayCommonsiO75541

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		55565, 1 hit in 865 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF821, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		55565
PharosiO75541, Tdark

Protein Ontology

More...PROi		PR:O75541
RNActiO75541, protein

Gene expression databases

BgeeiENSG00000102984, Expressed in cortical plate and 145 other tissues
ExpressionAtlasiO75541, baseline and differential
GenevisibleiO75541, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 2 hits
SUPFAMiSSF57667, SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 2 hits
PS50157, ZINC_FINGER_C2H2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN821_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75541
Secondary accession number(s): A6NK48, B4DKK4, D3DWS3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 16, 2012
Last modified: December 2, 2020
This is version 174 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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