Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 149 (13 Feb 2019)
Sequence version 2 (16 Aug 2004)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

F-box only protein 24

Gene

FBXO24

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ubiquitin-protein transferase activity Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processUbl conjugation pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
F-box only protein 24
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FBXO24
Synonyms:FBX24
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000106336.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13595 FBXO24

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609097 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O75426

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000106336

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28037

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FBXO24

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001199091 – 580F-box only protein 24Add BLAST580

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O75426

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O75426

PeptideAtlas

More...
PeptideAtlasi
O75426

PRoteomics IDEntifications database

More...
PRIDEi
O75426

ProteomicsDB human proteome resource

More...
ProteomicsDBi
49996
49997 [O75426-2]
49998 [O75426-3]
49999 [O75426-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O75426

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O75426

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000106336 Expressed in 125 organ(s), highest expression level in right testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O75426 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O75426 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA050951

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Directly interacts with SKP1 and CUL1.By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117647, 8 interactors

Protein interaction database and analysis system

More...
IntActi
O75426, 16 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000416558

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O75426

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini36 – 82F-boxPROSITE-ProRule annotationAdd BLAST47
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati376 – 425RCC1Add BLAST50

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IQCV Eukaryota
ENOG41100N3 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017455

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000253007

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051571

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O75426

KEGG Orthology (KO)

More...
KOi
K10304

Identification of Orthologs from Complete Genome Data

More...
OMAi
HDIEHHP

Database of Orthologous Groups

More...
OrthoDBi
379673at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O75426

TreeFam database of animal gene trees

More...
TreeFami
TF328722

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12937 F-box-like, 1 hit
PF00415 RCC1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00256 FBOX, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50985 SSF50985, 1 hit
SSF81383 SSF81383, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50181 FBOX, 1 hit
PS50012 RCC1_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O75426-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGEKAVPLLR RRRVKRSCPS CGSELGVEEK RGKGNPISIQ LFPPELVEHI
60 70 80 90 100
ISFLPVRDLV ALGQTCRYFH EVCDGEGVWR RICRRLSPRL QDQGSGVRPW
110 120 130 140 150
KRAAILNYTK GLYFQAFGGR RRCLSKSVAP LLAHGYRRFL PTKDHVFILD
160 170 180 190 200
YVGTLFFLKN ALVSTLGQMQ WKRACRYVVL CRGAKDFASD PRCDTVYRKY
210 220 230 240 250
LYVLATREPQ EVVGTTSSRA CDCVEVYLQS SGQRVFKMTF HHSMTFKQIV
260 270 280 290 300
LVGQETQRAL LLLTEEGKIY SLVVNETQLD QPRSYTVQLA LRKVSHYLPH
310 320 330 340 350
LRVACMTSNQ SSTLYVTDQG GVYFEVHTPG VYRDLFGTLQ AFDPLDQQMP
360 370 380 390 400
LALSLPAKIL FCALGYNHLG LVDEFGRIFM QGNNRYGQLG TGDKMDRGEP
410 420 430 440 450
TQVCYLQRPI TLWCGLNHSL VLSQSSEFSK ELLGCGCGAG GRLPGWPKGS
460 470 480 490 500
ASFVKLQVKV PLCACALCAT RECLYILSSH DIEQHAPYRH LPASRVVGTP
510 520 530 540 550
EPSLGARAPQ DPGGMAQACE EYLSQIHSCQ TLQDRTEKMK EIVGWMPLMA
560 570 580
AQKDFFWEAL DMLQRAEGGG GGVGPPAPET
Length:580
Mass (Da):64,889
Last modified:August 16, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3863C6846AB6B940
GO
Isoform 2 (identifier: O75426-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     94-108: GSGVRPWKRAAILNY → D
     319-332: QGGVYFEVHTPGVY → PILCSWLQPPWPGG
     333-580: Missing.

Show »
Length:318
Mass (Da):36,353
Checksum:i025D9AF7342646F2
GO
Isoform 3 (identifier: O75426-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-12: MGEKAVPLLRRR → MVWESQQERGGQGPRRQEGRSREGAIRMVRGSQRRKLQKFTRLCGREEGL

Note: No experimental confirmation available.
Show »
Length:618
Mass (Da):69,336
Checksum:i5F6E800F4AF66B0E
GO
Isoform 4 (identifier: O75426-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: MGEKAVPLLRRRR → M

Note: No experimental confirmation available.
Show »
Length:568
Mass (Da):63,456
Checksum:iD6E1D0FBBB60538A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J4S8C9J4S8_HUMAN
F-box only protein 24
FBXO24
187Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9K0U2C9K0U2_HUMAN
F-box only protein 24
FBXO24
130Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WC52F8WC52_HUMAN
F-box only protein 24
FBXO24
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_049042302R → H. Corresponds to variant dbSNP:rs7801492Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0434581 – 13MGEKA…LRRRR → M in isoform 4. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_0434591 – 12MGEKA…LLRRR → MVWESQQERGGQGPRRQEGR SREGAIRMVRGSQRRKLQKF TRLCGREEGL in isoform 3. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_01135194 – 108GSGVR…AILNY → D in isoform 2. 1 PublicationAdd BLAST15
Alternative sequenceiVSP_011352319 – 332QGGVY…TPGVY → PILCSWLQPPWPGG in isoform 2. 1 PublicationAdd BLAST14
Alternative sequenceiVSP_011353333 – 580Missing in isoform 2. 1 PublicationAdd BLAST248

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF174604 mRNA Translation: AAF04525.1
AF053356 Genomic DNA Translation: AAC78801.1
AL136811 mRNA Translation: CAB66745.1
AK301864 mRNA Translation: BAG63303.1
AK302252 mRNA Translation: BAG63604.1
AC069281 Genomic DNA Translation: AAP21862.1
AC069281 Genomic DNA Translation: AAP21863.1
CH236956 Genomic DNA Translation: EAL23827.1
CH471091 Genomic DNA Translation: EAW76517.1
BC067293 mRNA Translation: AAH67293.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS55138.1 [O75426-4]
CCDS5698.1 [O75426-1]
CCDS5699.2 [O75426-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001156971.1, NM_001163499.1 [O75426-4]
NP_036304.2, NM_012172.4 [O75426-3]
NP_277041.1, NM_033506.2 [O75426-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.283764

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000241071; ENSP00000241071; ENSG00000106336 [O75426-1]
ENST00000427939; ENSP00000416558; ENSG00000106336 [O75426-3]
ENST00000465843; ENSP00000419602; ENSG00000106336 [O75426-2]
ENST00000468962; ENSP00000420239; ENSG00000106336 [O75426-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26261

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:26261

UCSC genome browser

More...
UCSCi
uc003uvl.2 human [O75426-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF174604 mRNA Translation: AAF04525.1
AF053356 Genomic DNA Translation: AAC78801.1
AL136811 mRNA Translation: CAB66745.1
AK301864 mRNA Translation: BAG63303.1
AK302252 mRNA Translation: BAG63604.1
AC069281 Genomic DNA Translation: AAP21862.1
AC069281 Genomic DNA Translation: AAP21863.1
CH236956 Genomic DNA Translation: EAL23827.1
CH471091 Genomic DNA Translation: EAW76517.1
BC067293 mRNA Translation: AAH67293.1
CCDSiCCDS55138.1 [O75426-4]
CCDS5698.1 [O75426-1]
CCDS5699.2 [O75426-3]
RefSeqiNP_001156971.1, NM_001163499.1 [O75426-4]
NP_036304.2, NM_012172.4 [O75426-3]
NP_277041.1, NM_033506.2 [O75426-1]
UniGeneiHs.283764

3D structure databases

ProteinModelPortaliO75426
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi117647, 8 interactors
IntActiO75426, 16 interactors
STRINGi9606.ENSP00000416558

PTM databases

iPTMnetiO75426
PhosphoSitePlusiO75426

Polymorphism and mutation databases

BioMutaiFBXO24

Proteomic databases

jPOSTiO75426
PaxDbiO75426
PeptideAtlasiO75426
PRIDEiO75426
ProteomicsDBi49996
49997 [O75426-2]
49998 [O75426-3]
49999 [O75426-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000241071; ENSP00000241071; ENSG00000106336 [O75426-1]
ENST00000427939; ENSP00000416558; ENSG00000106336 [O75426-3]
ENST00000465843; ENSP00000419602; ENSG00000106336 [O75426-2]
ENST00000468962; ENSP00000420239; ENSG00000106336 [O75426-4]
GeneIDi26261
KEGGihsa:26261
UCSCiuc003uvl.2 human [O75426-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26261
EuPathDBiHostDB:ENSG00000106336.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FBXO24
HGNCiHGNC:13595 FBXO24
HPAiHPA050951
MIMi609097 gene
neXtProtiNX_O75426
OpenTargetsiENSG00000106336
PharmGKBiPA28037

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IQCV Eukaryota
ENOG41100N3 LUCA
GeneTreeiENSGT00390000017455
HOGENOMiHOG000253007
HOVERGENiHBG051571
InParanoidiO75426
KOiK10304
OMAiHDIEHHP
OrthoDBi379673at2759
PhylomeDBiO75426
TreeFamiTF328722

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FBXO24 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
26261

Protein Ontology

More...
PROi
PR:O75426

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000106336 Expressed in 125 organ(s), highest expression level in right testis
ExpressionAtlasiO75426 baseline and differential
GenevisibleiO75426 HS

Family and domain databases

Gene3Di2.130.10.30, 1 hit
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
PF00415 RCC1, 1 hit
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SUPFAMiSSF50985 SSF50985, 1 hit
SSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit
PS50012 RCC1_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFBX24_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75426
Secondary accession number(s): A4D2D4
, B4DX91, B4DY42, Q9H0G1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: August 16, 2004
Last modified: February 13, 2019
This is version 149 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again