Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 25 of 40  Show
  1. 1
    "Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein."
    Huggenvik J.I., Michelson R.J., Collard M.W., Ziemba A.J., Gurley P., Mowen K.A.
    Mol. Endocrinol. 12:1619-1639(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), MUTAGENESIS OF ARG-302 AND LYS-304.
    Category: Pathology & Biotech, Sequences.
    Tissue: Choriocarcinoma.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 other entries.

  2. 2
    "Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas."
    Manne U., Gary B.D., Oelschlager D.K., Weiss H.L., Frost A.R., Grizzle W.E.
    Clin. Cancer Res. 7:3495-3503(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), VARIANTS VAL-186; ASN-191; ILE-191; 199-CYS-ASP-ASN-ASP-202; ASP-202; LYS-218; 350-GLY-GLN-THR-352; HIS-356; ASN-364; HIS-367; LEU-370; PHE-397; ALA-442; LYS-449; 451-GLY-ILE-452; HIS-468; LEU-479; LYS-498; ASN-526; LEU-530; 537-HIS-LEU-538; HIS-542; GLY-545 AND VAL-545, ROLE IN NEOPLASIA.
    Category: Function, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes."
    Yip L., Su L., Sheng D., Chang P., Atkinson M., Czesak M., Albert P.R., Collier A.R., Turley S.J., Fathman C.G., Creusot R.J.
    Nat. Immunol. 10:1026-1033(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Category: Function, Subcellular Location, Expression, Sequences.
    Tissue: Pancreas.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 11 other entries.

  4. 4
    "Cloning and sequence analysis of the cDNA for human suppressin (spn)."
    LeBoeuf R.D., Blalock J.E., Tauber J.D.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
    Category: Sequences.
    Tissue: Mammary gland.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
    Category: Sequences.
    Tissue: Brain and Caudate nucleus.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12927 other entries.

  6. 6
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Ovary.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  7. 7
    "Nuclear DEAF-1-related (NUDR) protein contains a novel DNA binding domain and represses transcription of the heterogeneous nuclear ribonucleoprotein A2/B1 promoter."
    Michelson R.J., Collard M.W., Ziemba A.J., Persinger J., Bartholomew B., Huggenvik J.I.
    J. Biol. Chem. 274:30510-30519(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation."
    Bottomley M.J., Collard M.W., Huggenvik J.I., Liu Z., Gibson T.J., Sattler M.
    Nat. Struct. Biol. 8:626-633(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF SAND DOMAIN, MUTAGENESIS OF TYR-215; ARG-226; ARG-246; LYS-250; TRP-252 AND LYS-253.
    Category: Function, Pathology & Biotech, Family & Domains.
    Source: UniProtKB/Swiss-Prot (reviewed).
  9. 9
    "Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland."
    Barker H.E., Smyth G.K., Wettenhall J., Ward T.A., Bath M.L., Lindeman G.J., Visvader J.E.
    BMC Dev. Biol. 8:94-94(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Category: Function.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 11 other entries.

  10. 10
    "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 5354 and mapped to 17 other entries.

  11. 11
    "Deformed epidermal autoregulatory factor-1 (DEAF1) interacts with the Ku70 subunit of the DNA-dependent protein kinase complex."
    Jensik P.J., Huggenvik J.I., Collard M.W.
    PLoS ONE 7:E33404-E33404(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: DNA-BINDING, IDENTIFICATION IN A COMPLEX WITH XRCC5 AND XRCC6, SUBCELLULAR LOCATION, PHOSPHORYLATION BY DNA-PK COMPLEX.
    Category: Function, Subcellular Location, PTM / Processing, Interaction.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 2 and mapped to 6 other entries.

  12. 12
    "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-176 AND THR-432, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 13410 other entries.

  13. 13
    Cited for: FUNCTION, INTERACTION WITH XRCC6, DNA-BINDING, TISSUE SPECIFICITY, INVOLVEMENT IN MRD24, VARIANTS MRD24 TRP-224; SER-228; SER-254 AND PRO-264, CHARACTERIZATION OF VARIANTS MRD24 TRP-224; SER-228; SER-254 AND PRO-264, MUTAGENESIS OF LYS-250 AND LYS-253.
    Category: Function, Pathology & Biotech, Expression, Interaction, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 and mapped to 11 other entries.

  14. 14
    Cited for: STRUCTURE BY NMR OF 496-544 IN COMPLEX WITH ZINC IONS.
    Category: Interaction, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  15. 15
    "Retraction notice to 'Structure and functional analysis of the MYND domain' [J. Mol. Biol. (2006) 358, 498-508]."
    Spadaccini R., Perrin H., Bottomley M.J., Ansieau S., Sattler M.
    J. Mol. Biol. 376:1523-1523(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: RETRACTION: STRUCTURE BY NMR OF 496-544 IN COMPLEX WITH ZINC IONS.
    Category: Interaction, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  16. 16
    Cited for: STRUCTURE BY NMR OF 501-544 IN COMPLEX WITH ZINC IONS, SUBUNIT, INTERACTION WITH NCOR1 AND NCOR2, MUTAGENESIS OF HIS-538.
    Category: Pathology & Biotech, Interaction, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 other entries.

  17. 17
    Category: Pathology & Biotech, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 7 other entries.

  18. 18
    "Recessive DEAF1 mutation associates with autism, intellectual disability, basal ganglia dysfunction and epilepsy."
    Rajab A., Schuelke M., Gill E., Zwirner A., Seifert F., Morales Gonzalez S., Knierim E.
    J. Med. Genet. 52:607-611(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: INVOLVEMENT IN DYSEIDD.
    Category: Pathology & Biotech.
    Source: UniProtKB/Swiss-Prot (reviewed).
  19. 19
    "Novel homozygous DEAF1 variant suspected in causing white matter disease, intellectual disability, and microcephaly."
    Faqeih E.A., Al-Owain M., Colak D., Kenana R., Al-Yafee Y., Al-Dosary M., Al-Saman A., Albalawi F., Al-Sarar D., Domiaty D., Daghestani M., Kaya N.
    Am. J. Med. Genet. A 164A:1565-1570(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANT TRP-226.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  20. 20
    "Identification of a nuclear export signal and protein interaction domains in deformed epidermal autoregulatory factor-1 (DEAF-1)."
    Jensik P.J., Huggenvik J.I., Collard M.W.
    J. Biol. Chem. 279:32692-32699(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: DEAF1 has nuclear export signal and protein interaction domains.
    Source: GeneRIF:10522.

    This publication is mapped to 1 other entry.

  21. 21
    Category: Interaction.
    Source: IntAct:O75398.

    This publication is mapped to 1656 other entries.

  22. 22
    "Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism."
    Czesak M., Lemonde S., Peterson E.A., Rogaeva A., Albert P.R.
    J. Neurosci. 26:1864-1871(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Cell-specific regulation by Deaf-1 could underlie region-specific alterations in 5-HT1A receptor expression in different mood disorders.
    Source: GeneRIF:10522.

    This publication is mapped to 19 other entries.

  23. 23
    "Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder."
    Szewczyk B., Albert P.R., Burns A.M., Czesak M., Overholser J.C., Jurjus G.J., Meltzer H.Y., Konick L.C., Dieter L., Herbst N., May W., Rajkowska G., Stockmeier C.A., Austin M.C.
    Int. J. Neuropsychopharmacol. 12:155-168(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: In this study the NUDR immunoreactivity as measured by Western blot was significantly decreased in the prefrontal cortex of female depressed subjects (42% p=0.02) and unchanged in male depressed subjects relative to gender-matched control subjects.
    Source: GeneRIF:10522.

    This publication is mapped to 5 other entries.

  24. 24
    Category: Interaction.
    Source: IntAct:O75398.

    This publication is mapped to 271 other entries.

  25. 25
    "Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism."
    Egli R.J., Southam L., Wilkins J.M., Lorenzen I., Pombo-Suarez M., Gonzalez A., Carr A., Chapman K., Loughlin J.
    Arthritis Rheum. 60:2055-2064(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: DEAF-1 is a trans-acting factor that merits further investigation as a potential tool for modulating GDF5 expression.
    Source: GeneRIF:10522.

    This publication is mapped to 14 other entries.

1 to 25 of 40  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again