COQ9

Functionⁱ

Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Binds a phospholipid of at least 10 carbons in each acyl group. May be required to present its bound-lipid to COQ7.1 Publication

Pathwayⁱ: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.By similarity
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

GO - Molecular functionⁱ

lipid binding
Source: UniProtKB
Inferred from direct assayⁱ
- 25339443
protein homodimerization activity
Source: UniProtKB
Inferred from direct assayⁱ
- 25339443

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mitochondrial electron transport, NADH to ubiquinone Source: Ensembl
ubiquinone biosynthetic process Source: UniProtKB

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Ubiquinone biosynthesis
Ligand	Lipid-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-2142789 Ubiquinol biosynthesis
UniPathwayⁱ	UPA00232

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ubiquinone biosynthesis protein COQ9, mitochondrial
Gene namesⁱ	Name:COQ9 Synonyms:C16orf49 ORF Names:HSPC326, PSEC0129
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 16

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000088682.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:25302 COQ9
MIMⁱ	612837 gene
neXtProtⁱ	NX_O75208

Keywords - Cellular componentⁱ

Mitochondrion

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Coenzyme Q10 deficiency, primary, 5 (COQ10D5)1 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA form of coenzyme Q10 deficiency, an autosomal recessive disorder with variable manifestations consistent with 5 major phenotypes. The phenotypes include an encephalomyopathic form with seizures and ataxia; a multisystem infantile form with encephalopathy, cardiomyopathy and renal failure; a predominantly cerebellar form with ataxia and cerebellar atrophy; Leigh syndrome with growth retardation; and an isolated myopathic form.

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	190	L → E: Impairs interaction with COQ7. 1 Publication	1
Mutagenesisⁱ	227	M → E: Impairs interaction with COQ7. 1 Publication	1
Mutagenesisⁱ	237	D → K: Impairs interaction with COQ7. 1 Publication	1
Mutagenesisⁱ	240	W → D or K: Abolishes interaction with COQ7. 1 Publication	1
Mutagenesisⁱ	241	Y → D or K: Abolishes interaction with COQ7. 1 Publication	1
Mutagenesisⁱ	256	L → K: Impairs interaction with COQ7. 1 Publication	1

Keywords - Diseaseⁱ

Primary mitochondrial disease

Organism-specific databases

DisGeNET More...DisGeNETⁱ	57017
MalaCards human disease database More...MalaCardsⁱ	COQ9
MIMⁱ	614654 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000088682
Orphanetⁱ	319678 Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
PharmGKBⁱ	PA142672085

Polymorphism and mutation databases

BioMutaⁱ	COQ9

BioMutaⁱ

COQ9

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transit peptideⁱ	1 – 44	MitochondrionSequence analysisAdd BLAST		44
ChainⁱPRO_0000228637	45 – 318	Ubiquinone biosynthesis protein COQ9, mitochondrialAdd BLAST		274

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	175	N6-acetyllysineBy similarity		1

Keywords - PTMⁱ

Acetylation

Proteomic databases

EPDⁱ	O75208
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O75208
PaxDbⁱ	O75208
PeptideAtlas More...PeptideAtlasⁱ	O75208
PRIDEⁱ	O75208
ProteomicsDBⁱ	49869 49870 [O75208-2]
TopDownProteomicsⁱ	O75208-1 [O75208-1]

PTM databases

iPTMnetⁱ	O75208
PhosphoSitePlusⁱ	O75208

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000088682 Expressed in 169 organ(s), highest expression level in apex of heart
CleanExⁱ	HS_COQ9
ExpressionAtlasⁱ	O75208 baseline and differential
Genevisibleⁱ	O75208 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA040918

HPAⁱ

HPA040918

Interactionⁱ

Subunit structureⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
COQ5	Q5HYK3	6	EBI-724524,EBI-12577722
COQ7	Q99807	8	EBI-724524,EBI-11017131

GO - Molecular functionⁱ

protein homodimerization activity
Source: UniProtKB
Inferred from direct assayⁱ
- 25339443

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	121326, 180 interactors
ComplexPortalⁱ	CPX-3642 CoQ biosynthetic complex
IntActⁱ	O75208, 56 interactors
STRINGⁱ	9606.ENSP00000262507

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	96 – 108	Combined sources	13
Helixⁱ	111 – 114	Combined sources	4
Helixⁱ	118 – 127	Combined sources	10
Helixⁱ	132 – 137	Combined sources	6
Beta strandⁱ	140 – 142	Combined sources	3
Helixⁱ	143 – 169	Combined sources	27
Helixⁱ	178 – 191	Combined sources	14
Helixⁱ	192 – 199	Combined sources	8
Helixⁱ	200 – 207	Combined sources	8
Turnⁱ	210 – 212	Combined sources	3
Helixⁱ	213 – 231	Combined sources	19
Helixⁱ	240 – 258	Combined sources	19
Helixⁱ	264 – 266	Combined sources	3
Helixⁱ	267 – 282	Combined sources	16
Helixⁱ	294 – 309	Combined sources	16

Show more details

3D structure databases

ProteinModelPortalⁱ	O75208
SMRⁱ	O75208
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	241 – 244	Lipid bindingCombined sources1 Publication		4

Domainⁱ

Structurally similar to the bacterial FadR protein (fatty acid metabolism regulator protein).1 Publication

Sequence similaritiesⁱ

Belongs to the COQ9 family.Curated

Keywords - Domainⁱ

Transit peptide

Phylogenomic databases

eggNOGⁱ	KOG2969 Eukaryota COG5590 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000009328
HOVERGENⁱ	HBG079760
InParanoidⁱ	O75208
KEGG Orthology (KO) More...KOⁱ	K18587
OMAⁱ	DPSWYTK
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0M72
PhylomeDBⁱ	O75208
TreeFamⁱ	TF324653

Family and domain databases

InterProⁱ	View protein in InterPro IPR013718 COQ9 IPR012762 Ubiq_biosynth_COQ9
PANTHERⁱ	PTHR21427 PTHR21427, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08511 COQ9, 1 hit
TIGRFAMsⁱ	TIGR02396 diverge_rpsU, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 7 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: O75208-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAAAAVSGAL GRAGWRLLQL RCLPVARCRQ ALVPRAFHAS AVGLRSSDEQ 
        60         70         80         90        100
KQQPPNSFSQ QHSETQGAEK PDPESSHSPP RYTDQGGEEE EDYESEEQLQ 
       110        120        130        140        150
HRILTAALEF VPAHGWTAEA IAEGAQSLGL SSAAASMFGK DGSELILHFV 
       160        170        180        190        200
TQCNTRLTRV LEEEQKLVQL GQAEKRKTDQ FLRDAVETRL RMLIPYIEHW 
       210        220        230        240        250
PRALSILMLP HNIPSSLSLL TSMVDDMWHY AGDQSTDFNW YTRRAMLAAI 
       260        270        280        290        300
YNTTELVMMQ DSSPDFEDTW RFLENRVNDA MNMGHTAKQV KSTGEALVQG 
       310 
LMGAAVTLKN LTGLNQRR

Length:318

Mass (Da):35,509

Last modified:November 1, 1998 - v1

Checksum:ⁱF648B4B409E749DA

GO

Isoform 2 (identifier: O75208-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
127-135: SLGLSSAAA → VCIGEGGAT
136-318: Missing.

« Hide

        10         20         30         40         50
MAAAAVSGAL GRAGWRLLQL RCLPVARCRQ ALVPRAFHAS AVGLRSSDEQ 
        60         70         80         90        100
KQQPPNSFSQ QHSETQGAEK PDPESSHSPP RYTDQGGEEE EDYESEEQLQ 
       110        120        130 
HRILTAALEF VPAHGWTAEA IAEGAQVCIG EGGAT

Note: No experimental confirmation available.

Show »

Length:135

Mass (Da):14,505

Checksum:ⁱ9C945AE4C90B6CC1

GO

Computationally mapped potential isoform sequencesⁱ

There are 7 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

H3BRC0	H3BRC0_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	207	Annotation score:
H3BPC6	H3BPC6_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	188	Annotation score:
H3BVA5	H3BVA5_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	172	Annotation score:
H3BSJ5	H3BSJ5_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	283	Annotation score:
H3BNT2	H3BNT2_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	303	Annotation score:
H3BPY0	H3BPY0_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	89	Annotation score:
H3BPW3	H3BPW3_HUMAN	Ubiquinone biosynthesis protein COQ... Ubiquinone biosynthesis protein COQ9, mitochondrial	COQ9	102	Annotation score:

Sequence cautionⁱ

The sequence AAF29004 differs from that shown. Reason: Frameshift at positions 26, 133, 138 and 141.Curated

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_017683	127 – 135	SLGLSSAAA → VCIGEGGAT in isoform 2. 1 Publication		9
Alternative sequenceⁱVSP_017684	136 – 318	Missing in isoform 2. 1 PublicationAdd BLAST		183

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF161444 mRNA Translation: AAF29004.1 Frameshift. AK075438 mRNA Translation: BAC11621.1 AK290627 mRNA Translation: BAF83316.1 AC004382 Genomic DNA Translation: AAC24313.1 CH471092 Genomic DNA Translation: EAW82928.1 BC001478 mRNA Translation: AAH01478.2 BC054340 mRNA Translation: AAH54340.2 BC064946 mRNA Translation: AAH64946.1 AL136884 mRNA Translation: CAB66818.2
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS32459.1 [O75208-1]
PIRⁱ	T46490
NCBI Reference Sequences More...RefSeqⁱ	NP_064708.1, NM_020312.3 [O75208-1]
UniGeneⁱ	Hs.513632

Genome annotation databases

Ensemblⁱ	ENST00000262507; ENSP00000262507; ENSG00000088682 [O75208-1]
GeneIDⁱ	57017
KEGGⁱ	hsa:57017
UCSC genome browser More...UCSCⁱ	uc002elq.4 human [O75208-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O75208	HCG2025883, isoform CRA_c		HUMAN		318	UniRef100_O75208
cDNA FLJ57712, highly similar to Ubiquinone biosynthesis protein COQ9, mitochondrial		HUMAN		174
UPI00051FF437		HUMAN		235

Protein	Similar proteins		Species	Score	Length	Source
O75208	HCG2025883, isoform CRA_c		HUMAN		318	UniRef90_O75208
Uncharacterized protein		RHIRO		355
Coenzyme Q9		SAIBB		352
Uncharacterized protein		AOTNA		352
Uncharacterized protein		MACNE		324
+57

Protein	Similar proteins		Species	Score	Length	Source
O75208	HCG2025883, isoform CRA_c		HUMAN		318	UniRef50_O75208
Uncharacterized protein		RHIRO		355
Coenzyme Q9		SAIBB		352
Uncharacterized protein		AOTNA		352
Uncharacterized protein		MACNE		324
+169

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF161444 mRNA Translation: AAF29004.1 Frameshift. AK075438 mRNA Translation: BAC11621.1 AK290627 mRNA Translation: BAF83316.1 AC004382 Genomic DNA Translation: AAC24313.1 CH471092 Genomic DNA Translation: EAW82928.1 BC001478 mRNA Translation: AAH01478.2 BC054340 mRNA Translation: AAH54340.2 BC064946 mRNA Translation: AAH64946.1 AL136884 mRNA Translation: CAB66818.2
CCDSⁱ	CCDS32459.1 [O75208-1]
PIRⁱ	T46490
RefSeqⁱ	NP_064708.1, NM_020312.3 [O75208-1]
UniGeneⁱ	Hs.513632

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	4RHP	X-ray	2.39	A/B	84-318	[»]
ProteinModelPortalⁱ	O75208
SMRⁱ	O75208
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	121326, 180 interactors
ComplexPortalⁱ	CPX-3642 CoQ biosynthetic complex
IntActⁱ	O75208, 56 interactors
STRINGⁱ	9606.ENSP00000262507

PTM databases

iPTMnetⁱ	O75208
PhosphoSitePlusⁱ	O75208

Polymorphism and mutation databases

BioMutaⁱ	COQ9

BioMutaⁱ

COQ9

Proteomic databases

EPDⁱ	O75208
MaxQBⁱ	O75208
PaxDbⁱ	O75208
PeptideAtlasⁱ	O75208
PRIDEⁱ	O75208
ProteomicsDBⁱ	49869 49870 [O75208-2]
TopDownProteomicsⁱ	O75208-1 [O75208-1]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	57017
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000262507; ENSP00000262507; ENSG00000088682 [O75208-1]
GeneIDⁱ	57017
KEGGⁱ	hsa:57017
UCSCⁱ	uc002elq.4 human [O75208-1]

Organism-specific databases

CTDⁱ	57017
DisGeNETⁱ	57017
EuPathDBⁱ	HostDB:ENSG00000088682.13
GeneCardsⁱ	COQ9
HGNCⁱ	HGNC:25302 COQ9
HPAⁱ	HPA040918
MalaCardsⁱ	COQ9
MIMⁱ	612837 gene 614654 phenotype
neXtProtⁱ	NX_O75208
OpenTargetsⁱ	ENSG00000088682
Orphanetⁱ	319678 Encephalopathy-hypertrophic cardiomyopathy-renal tubular disease syndrome
PharmGKBⁱ	PA142672085
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2969 Eukaryota COG5590 LUCA
GeneTreeⁱ	ENSGT00390000009328
HOVERGENⁱ	HBG079760
InParanoidⁱ	O75208
KOⁱ	K18587
OMAⁱ	DPSWYTK
OrthoDBⁱ	EOG091G0M72
PhylomeDBⁱ	O75208
TreeFamⁱ	TF324653

Enzyme and pathway databases

UniPathwayⁱ	UPA00232
Reactomeⁱ	R-HSA-2142789 Ubiquinol biosynthesis

Miscellaneous databases

ChiTaRSⁱ	COQ9 human
GeneWikiⁱ	COQ9
GenomeRNAiⁱ	57017
Protein Ontology More...PROⁱ	PR:O75208
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000088682 Expressed in 169 organ(s), highest expression level in apex of heart
CleanExⁱ	HS_COQ9
ExpressionAtlasⁱ	O75208 baseline and differential
Genevisibleⁱ	O75208 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR013718 COQ9 IPR012762 Ubiq_biosynth_COQ9
PANTHERⁱ	PTHR21427 PTHR21427, 1 hit
Pfamⁱ	View protein in Pfam PF08511 COQ9, 1 hit
TIGRFAMsⁱ	TIGR02396 diverge_rpsU, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	COQ9_HUMAN
Accessionⁱ	O75208Primary (citable) accession number: O75208 Secondary accession number(s): A8K3L2 , Q7L5V7, Q7Z5T6, Q8NBL4, Q9NTJ2, Q9P056
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
	Last sequence update:	November 1, 1998
	Last modified:	November 7, 2018
	This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 16
Human chromosome 16: entries, gene names and cross-references to MIM
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PATHWAY comments
Index of metabolic and biosynthesis pathways
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O75208 (COQ9_HUMAN)

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Ubiquinone biosynthesis protein COQ9, mitochondrial

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: ubiquinone biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Keywords - Diseasei

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

Pathwayⁱ: ubiquinone biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ