UniProtKB - O75179 (ANR17_HUMAN)
Ankyrin repeat domain-containing protein 17
ANKRD17
Functioni
GO - Molecular functioni
- chromatin binding Source: UniProtKB
- RNA binding Source: UniProtKB
GO - Biological processi
- blood vessel maturation Source: Ensembl
- defense response to bacterium Source: UniProtKB
- innate immune response Source: UniProtKB
- negative regulation of smooth muscle cell differentiation Source: Ensembl
- positive regulation of cell cycle Source: UniProtKB
- positive regulation of G1/S transition of mitotic cell cycle Source: UniProtKB
- positive regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
- positive regulation of MDA-5 signaling pathway Source: UniProtKB
- positive regulation of RIG-I signaling pathway Source: UniProtKB
- regulation of DNA replication Source: UniProtKB
- viral process Source: UniProtKB-KW
Keywordsi
Molecular function | RNA-binding |
Biological process | Host-virus interaction, Immunity, Innate immunity |
Enzyme and pathway databases
PathwayCommonsi | O75179 |
Names & Taxonomyi
Protein namesi | Recommended name: Ankyrin repeat domain-containing protein 17Alternative name(s): Gene trap ankyrin repeat protein Serologically defined breast cancer antigen NY-BR-16 |
Gene namesi | Name:ANKRD17 Synonyms:GTAR, KIAA0697 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000132466.17 |
HGNCi | HGNC:23575, ANKRD17 |
MIMi | 615929, gene |
neXtProti | NX_O75179 |
Subcellular locationi
Nucleus
- nuclear membrane Source: HPA
- nucleoplasm Source: HPA
- nucleus Source: UniProtKB
Other locations
Keywords - Cellular componenti
Cytoplasm, NucleusPathology & Biotechi
Organism-specific databases
DisGeNETi | 26057 |
OpenTargetsi | ENSG00000132466 |
PharmGKBi | PA134943225 |
Miscellaneous databases
Pharosi | O75179, Tbio |
Polymorphism and mutation databases
BioMutai | ANKRD17 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000307917 | 1 – 2603 | Ankyrin repeat domain-containing protein 17Add BLAST | 2603 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 | |
Modified residuei | 19 | PhosphoserineCombined sources | 1 | |
Modified residuei | 50 | PhosphoserineBy similarity | 1 | |
Modified residuei | 156 | PhosphoserineCombined sources | 1 | |
Cross-linki | 318 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 803 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1457 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1635 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1639 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1696 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1700 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1709 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1874 | Asymmetric dimethylarginineBy similarity | 1 | |
Modified residuei | 2042 | Phosphoserine1 Publication | 1 | |
Modified residuei | 2044 | PhosphoserineBy similarity | 1 | |
Modified residuei | 2045 | PhosphoserineCombined sources1 Publication | 1 | |
Modified residuei | 2047 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2059 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2067 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2373 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2401 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | O75179 |
jPOSTi | O75179 |
MassIVEi | O75179 |
MaxQBi | O75179 |
PaxDbi | O75179 |
PeptideAtlasi | O75179 |
PRIDEi | O75179 |
ProteomicsDBi | 18505 33844 49850 [O75179-1] 49851 [O75179-2] 49852 [O75179-3] 49853 [O75179-4] 49854 [O75179-5] |
PTM databases
GlyGeni | O75179, 3 sites, 1 O-linked glycan (3 sites) |
iPTMneti | O75179 |
MetOSitei | O75179 |
PhosphoSitePlusi | O75179 |
SwissPalmi | O75179 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000132466, Expressed in sural nerve and 247 other tissues |
ExpressionAtlasi | O75179, baseline and differential |
Genevisiblei | O75179, HS |
Organism-specific databases
HPAi | ENSG00000132466, Low tissue specificity |
Interactioni
Subunit structurei
Interacts (via N-terminus) with NOD2.
Interacts with CDK2, MCM3, MCM5, MCM7, CDC6 and PCNA.
Interacts with MAVS and IFIH1.
Interacts (via the second ankyrin repeat cluster) with DDX58.
3 Publications(Microbial infection) Interacts with enterovirus 71/EV71 capsid protein VP1.
1 PublicationProtein-protein interaction databases
BioGRIDi | 117519, 65 interactors |
DIPi | DIP-47290N |
IntActi | O75179, 41 interactors |
MINTi | O75179 |
STRINGi | 9606.ENSP00000351416 |
Miscellaneous databases
RNActi | O75179, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 233 – 262 | ANK 1Add BLAST | 30 | |
Repeati | 266 – 295 | ANK 2Add BLAST | 30 | |
Repeati | 300 – 329 | ANK 3Add BLAST | 30 | |
Repeati | 333 – 362 | ANK 4Add BLAST | 30 | |
Repeati | 366 – 395 | ANK 5Add BLAST | 30 | |
Repeati | 400 – 429 | ANK 6Add BLAST | 30 | |
Repeati | 433 – 462 | ANK 7Add BLAST | 30 | |
Repeati | 466 – 495 | ANK 8Add BLAST | 30 | |
Repeati | 499 – 528 | ANK 9Add BLAST | 30 | |
Repeati | 533 – 562 | ANK 10Add BLAST | 30 | |
Repeati | 563 – 592 | ANK 11Add BLAST | 30 | |
Repeati | 596 – 625 | ANK 12Add BLAST | 30 | |
Repeati | 629 – 658 | ANK 13Add BLAST | 30 | |
Repeati | 663 – 692 | ANK 14Add BLAST | 30 | |
Repeati | 696 – 725 | ANK 15Add BLAST | 30 | |
Repeati | 1082 – 1111 | ANK 16Add BLAST | 30 | |
Repeati | 1115 – 1144 | ANK 17Add BLAST | 30 | |
Repeati | 1149 – 1178 | ANK 18Add BLAST | 30 | |
Repeati | 1182 – 1211 | ANK 19Add BLAST | 30 | |
Repeati | 1217 – 1246 | ANK 20Add BLAST | 30 | |
Repeati | 1251 – 1280 | ANK 21Add BLAST | 30 | |
Repeati | 1284 – 1313 | ANK 22Add BLAST | 30 | |
Repeati | 1319 – 1348 | ANK 23Add BLAST | 30 | |
Repeati | 1352 – 1381 | ANK 24Add BLAST | 30 | |
Repeati | 1385 – 1414 | ANK 25Add BLAST | 30 | |
Domaini | 1725 – 1789 | KHPROSITE-ProRule annotationAdd BLAST | 65 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 1442 – 1526 | Sequence analysisAdd BLAST | 85 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 96 – 110 | Gly-richAdd BLAST | 15 | |
Compositional biasi | 858 – 1008 | Gln-richAdd BLAST | 151 | |
Compositional biasi | 1603 – 1700 | Ser-richAdd BLAST | 98 | |
Compositional biasi | 1950 – 2106 | Ser-richAdd BLAST | 157 | |
Compositional biasi | 1966 – 2033 | Thr-richAdd BLAST | 68 |
Keywords - Domaini
ANK repeat, Coiled coil, RepeatPhylogenomic databases
eggNOGi | KOG0504, Eukaryota KOG4369, Eukaryota |
GeneTreei | ENSGT00940000153768 |
HOGENOMi | CLU_000590_0_1_1 |
InParanoidi | O75179 |
OMAi | FGANIDH |
OrthoDBi | 1115202at2759 |
PhylomeDBi | O75179 |
TreeFami | TF328552 |
Family and domain databases
Gene3Di | 1.25.40.20, 8 hits 3.30.1370.10, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf |
Pfami | View protein in Pfam PF00023, Ank, 2 hits PF12796, Ank_2, 9 hits PF00013, KH_1, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 25 hits SM00322, KH, 1 hit |
SUPFAMi | SSF48403, SSF48403, 3 hits SSF54791, SSF54791, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 20 hits PS50084, KH_TYPE_1, 1 hit |
s (7+)i Sequence
Sequence statusi: Complete.
This entry describes 7 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 7 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MEKATVPVAA ATAAEGEGSP PAVAAVAGPP AAAEVGGGVG GSSRARSASS
60 70 80 90 100
PRGMVRVCDL LLKKKPPQQQ HHKAKRNRTC RPPSSSESSS DSDNSGGGGG
110 120 130 140 150
GGGGGGGGGG TSSNNSEEEE DDDDEEEEVS EVESFILDQD DLENPMLETA
160 170 180 190 200
SKLLLSGTAD GADLRTVDPE TQARLEALLE AAGIGKLSTA DGKAFADPEV
210 220 230 240 250
LRRLTSSVSC ALDEAAAALT RMRAESTANA GQSDNRSLAE ACSEGDVNAV
260 270 280 290 300
RKLLIEGRSV NEHTEEGESL LCLACSAGYY ELAQVLLAMH ANVEDRGIKG
310 320 330 340 350
DITPLMAAAN GGHVKIVKLL LAHKADVNAQ SSTGNTALTY ACAGGYVDVV
360 370 380 390 400
KVLLESGASI EDHNENGHTP LMEAGSAGHV EVARLLLENG AGINTHSNEF
410 420 430 440 450
KESALTLACY KGHLEMVRFL LEAGADQEHK TDEMHTALME ACMDGHVEVA
460 470 480 490 500
RLLLDSGAQV NMPADSFESP LTLAACGGHV ELAALLIERG ASLEEVNDEG
510 520 530 540 550
YTPLMEAARE GHEEMVALLL GQGANINAQT EETQETALTL ACCGGFLEVA
560 570 580 590 600
DFLIKAGADI ELGCSTPLME AAQEGHLELV KYLLAAGANV HATTATGDTA
610 620 630 640 650
LTYACENGHT DVADVLLQAG ADLEHESEGG RTPLMKAARA GHVCTVQFLI
660 670 680 690 700
SKGANVNRTT ANNDHTVLSL ACAGGHLAVV ELLLAHGADP THRLKDGSTM
710 720 730 740 750
LIEAAKGGHT SVVCYLLDYP NNLLSAPPPD VTQLTPPSHD LNRAPRVPVQ
760 770 780 790 800
ALPMVVPPQE PDKPPANVAT TLPIRNKAAS KQKSSSHLPA NSQDVQGYIT
810 820 830 840 850
NQSPESIVEE AQGKLTELEQ RIKEAIEKNA QLQSLELAHA DQLTKEKIEE
860 870 880 890 900
LNKTREEQIQ KKQKILEELQ KVERELQLKT QQQLKKQYLE VKAQRIQLQQ
910 920 930 940 950
QQQQSCQHLG LLTPVGVGEQ LSEGDYARLQ QVDPVLLKDE PQQTAAQMGF
960 970 980 990 1000
APIQPLAMPQ ALPLAAGPLP PGSIANLTEL QGVIVGQPVL GQAQLAGLGQ
1010 1020 1030 1040 1050
GILTETQQGL MVASPAQTLN DTLDDIMAAV SGRASAMSNT PTHSIAASIS
1060 1070 1080 1090 1100
QPQTPTPSPI ISPSAMLPIY PAIDIDAQTE SNHDTALTLA CAGGHEELVQ
1110 1120 1130 1140 1150
TLLERGASIE HRDKKGFTPL ILAATAGHVG VVEILLDNGA DIEAQSERTK
1160 1170 1180 1190 1200
DTPLSLACSG GRQEVVELLL ARGANKEHRN VSDYTPLSLA ASGGYVNIIK
1210 1220 1230 1240 1250
ILLNAGAEIN SRTGSKLGIS PLMLAAMNGH TAAVKLLLDM GSDINAQIET
1260 1270 1280 1290 1300
NRNTALTLAC FQGRTEVVSL LLDRKANVEH RAKTGLTPLM EAASGGYAEV
1310 1320 1330 1340 1350
GRVLLDKGAD VNAPPVPSSR DTALTIAADK GHYKFCELLI GRGAHIDVRN
1360 1370 1380 1390 1400
KKGNTPLWLA ANGGHLDVVQ LLVQAGADVD AADNRKITPL MAAFRKGHVK
1410 1420 1430 1440 1450
VVRYLVKEVN QFPSDSECMR YIATITDKEM LKKCHLCMES IVQAKDRQAA
1460 1470 1480 1490 1500
EANKNASILL EELDLEKLRE ESRRLALAAK REKRKEKRRK KKEEQRRKLE
1510 1520 1530 1540 1550
EIEAKNKENF ELQAAQEKEK LKVEDEPEVL TEPPSATTTT TIGISATWTT
1560 1570 1580 1590 1600
LAGSHGKRNN TITTTSSKRK NRKNKITPEN VQIIFDDPLP ISYSQPEKVN
1610 1620 1630 1640 1650
GESKSSSTSE SGDSDNMRIS SCSDESSNSN SSRKSDNHSP AVVTTTVSSK
1660 1670 1680 1690 1700
KQPSVLVTFP KEERKSVSGK ASIKLSETIS EGTSNSLSTC TKSGPSPLSS
1710 1720 1730 1740 1750
PNGKLTVASP KRGQKREEGW KEVVRRSKKV SVPSTVISRV IGRGGCNINA
1760 1770 1780 1790 1800
IREFTGAHID IDKQKDKTGD RIITIRGGTE STRQATQLIN ALIKDPDKEI
1810 1820 1830 1840 1850
DELIPKNRLK SSSANSKIGS SAPTTTAANT SLMGIKMTTV ALSSTSQTAT
1860 1870 1880 1890 1900
ALTVPAISSA STHKTIKNPV NNVRPGFPVS LPLAYPPPQF AHALLAAQTF
1910 1920 1930 1940 1950
QQIRPPRLPM THFGGTFPPA QSTWGPFPVR PLSPARATNS PKPHMVPRHS
1960 1970 1980 1990 2000
NQNSSGSQVN SAGSLTSSPT TTTSSSASTV PGTSTNGSPS SPSVRRQLFV
2010 2020 2030 2040 2050
TVVKTSNATT TTVTTTASNN NTAPTNATYP MPTAKEHYPV SSPSSPSPPA
2060 2070 2080 2090 2100
QPGGVSRNSP LDCGSASPNK VASSSEQEAG SPPVVETTNT RPPNSSSSSG
2110 2120 2130 2140 2150
SSSAHSNQQQ PPGSVSQEPR PPLQQSQVPP PEVRMTVPPL ATSSAPVAVP
2160 2170 2180 2190 2200
STAPVTYPMP QTPMGCPQPT PKMETPAIRP PPHGTTAPHK NSASVQNSSV
2210 2220 2230 2240 2250
AVLSVNHIKR PHSVPSSVQL PSTLSTQSAC QNSVHPANKP IAPNFSAPLP
2260 2270 2280 2290 2300
FGPFSTLFEN SPTSAHAFWG GSVVSSQSTP ESMLSGKSSY LPNSDPLHQS
2310 2320 2330 2340 2350
DTSKAPGFRP PLQRPAPSPS GIVNMDSPYG SVTPSSTHLG NFASNISGGQ
2360 2370 2380 2390 2400
MYGPGAPLGG APAAANFNRQ HFSPLSLLTP CSSASNDSSA QSVSSGVRAP
2410 2420 2430 2440 2450
SPAPSSVPLG SEKPSNVSQD RKVPVPIGTE RSARIRQTGT SAPSVIGSNL
2460 2470 2480 2490 2500
STSVGHSGIW SFEGIGGNQD KVDWCNPGMG NPMIHRPMSD PGVFSQHQAM
2510 2520 2530 2540 2550
ERDSTGIVTP SGTFHQHVPA GYMDFPKVGG MPFSVYGNAM IPPVAPIPDG
2560 2570 2580 2590 2600
AGGPIFNGPH AADPSWNSLI KMVSSSTENN GPQTVWTGPW APHMNSVHMN
QLG
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0YM23 | H0YM23_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD17 | 2,487 | Annotation score: | ||
H0YLQ3 | H0YLQ3_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD17 | 862 | Annotation score: | ||
A0A1W2PQ15 | A0A1W2PQ15_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD17 | 1,123 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 304 | P → S in BAA31672 (PubMed:9734811).Curated | 1 | |
Sequence conflicti | 705 | A → P in AAG48253 (PubMed:12747765).Curated | 1 | |
Sequence conflicti | 713 | V → G in AAG48253 (PubMed:12747765).Curated | 1 | |
Sequence conflicti | 1137 | D → G in BAB15260 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1163 | Q → P in AAG48253 (PubMed:12747765).Curated | 1 | |
Sequence conflicti | 1391 | Missing in CAD38571 (PubMed:17974005).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_036711 | 2560 | H → Y. Corresponds to variant dbSNP:rs2306059Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_054757 | 1 – 130 | MEKAT…EEEVS → MVETAAEMEAYVLEDIL in isoform 7. CuratedAdd BLAST | 130 | |
Alternative sequenceiVSP_028859 | 742 – 751 | NRAPRVPVQA → TDNIFPRLVC in isoform 5. 1 Publication | 10 | |
Alternative sequenceiVSP_028860 | 752 – 2603 | Missing in isoform 5. 1 PublicationAdd BLAST | 1852 | |
Alternative sequenceiVSP_047048 | 778 – 1028 | Missing in isoform 6. CuratedAdd BLAST | 251 | |
Alternative sequenceiVSP_028861 | 982 – 1010 | GVIVG…TQQGL → VLSSLLQPCFLSTLPLILMH RLRVIMTRR in isoform 4. 1 PublicationAdd BLAST | 29 | |
Alternative sequenceiVSP_028862 | 1011 – 1603 | Missing in isoform 4. 1 PublicationAdd BLAST | 593 | |
Alternative sequenceiVSP_028863 | 1028 | Missing in isoform 2. 1 Publication | 1 | |
Alternative sequenceiVSP_028864 | 1176 – 1187 | KEHRN…DYTPL → YRSTGMVLITHL in isoform 3. 1 PublicationAdd BLAST | 12 | |
Alternative sequenceiVSP_028865 | 1188 – 2603 | Missing in isoform 3. 1 PublicationAdd BLAST | 1416 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF308285 mRNA Translation: AAG48253.1 Frameshift. AC053527 Genomic DNA No translation available. AC095053 Genomic DNA No translation available. AC105757 Genomic DNA No translation available. CH471057 Genomic DNA Translation: EAX05655.1 BC004173 mRNA Translation: AAH04173.1 Sequence problems. BC007747 mRNA Translation: AAH07747.2 BC019963 mRNA Translation: AAH19963.1 BC043394 mRNA Translation: AAH43394.1 AB014597 mRNA Translation: BAA31672.2 AL831903 mRNA Translation: CAD38571.2 AK025859 mRNA Translation: BAB15260.1 Sequence problems. |
CCDSi | CCDS34003.1 [O75179-6] CCDS34004.1 [O75179-1] CCDS68721.1 [O75179-7] |
PIRi | T00353 |
RefSeqi | NP_001273700.1, NM_001286771.2 [O75179-7] NP_056389.1, NM_015574.1 [O75179-2] NP_115593.3, NM_032217.4 [O75179-1] NP_942592.1, NM_198889.2 [O75179-6] |
Genome annotation databases
Ensembli | ENST00000330838; ENSP00000332265; ENSG00000132466 [O75179-6] ENST00000358602; ENSP00000351416; ENSG00000132466 [O75179-1] ENST00000509867; ENSP00000427151; ENSG00000132466 [O75179-7] |
GeneIDi | 26057 |
KEGGi | hsa:26057 |
UCSCi | uc003hgo.5, human [O75179-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF308285 mRNA Translation: AAG48253.1 Frameshift. AC053527 Genomic DNA No translation available. AC095053 Genomic DNA No translation available. AC105757 Genomic DNA No translation available. CH471057 Genomic DNA Translation: EAX05655.1 BC004173 mRNA Translation: AAH04173.1 Sequence problems. BC007747 mRNA Translation: AAH07747.2 BC019963 mRNA Translation: AAH19963.1 BC043394 mRNA Translation: AAH43394.1 AB014597 mRNA Translation: BAA31672.2 AL831903 mRNA Translation: CAD38571.2 AK025859 mRNA Translation: BAB15260.1 Sequence problems. |
CCDSi | CCDS34003.1 [O75179-6] CCDS34004.1 [O75179-1] CCDS68721.1 [O75179-7] |
PIRi | T00353 |
RefSeqi | NP_001273700.1, NM_001286771.2 [O75179-7] NP_056389.1, NM_015574.1 [O75179-2] NP_115593.3, NM_032217.4 [O75179-1] NP_942592.1, NM_198889.2 [O75179-6] |
3D structure databases
SMRi | O75179 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 117519, 65 interactors |
DIPi | DIP-47290N |
IntActi | O75179, 41 interactors |
MINTi | O75179 |
STRINGi | 9606.ENSP00000351416 |
PTM databases
GlyGeni | O75179, 3 sites, 1 O-linked glycan (3 sites) |
iPTMneti | O75179 |
MetOSitei | O75179 |
PhosphoSitePlusi | O75179 |
SwissPalmi | O75179 |
Polymorphism and mutation databases
BioMutai | ANKRD17 |
Proteomic databases
EPDi | O75179 |
jPOSTi | O75179 |
MassIVEi | O75179 |
MaxQBi | O75179 |
PaxDbi | O75179 |
PeptideAtlasi | O75179 |
PRIDEi | O75179 |
ProteomicsDBi | 18505 33844 49850 [O75179-1] 49851 [O75179-2] 49852 [O75179-3] 49853 [O75179-4] 49854 [O75179-5] |
Protocols and materials databases
Antibodypediai | 24452, 137 antibodies |
Genome annotation databases
Ensembli | ENST00000330838; ENSP00000332265; ENSG00000132466 [O75179-6] ENST00000358602; ENSP00000351416; ENSG00000132466 [O75179-1] ENST00000509867; ENSP00000427151; ENSG00000132466 [O75179-7] |
GeneIDi | 26057 |
KEGGi | hsa:26057 |
UCSCi | uc003hgo.5, human [O75179-1] |
Organism-specific databases
CTDi | 26057 |
DisGeNETi | 26057 |
EuPathDBi | HostDB:ENSG00000132466.17 |
GeneCardsi | ANKRD17 |
HGNCi | HGNC:23575, ANKRD17 |
HPAi | ENSG00000132466, Low tissue specificity |
MIMi | 615929, gene |
neXtProti | NX_O75179 |
OpenTargetsi | ENSG00000132466 |
PharmGKBi | PA134943225 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0504, Eukaryota KOG4369, Eukaryota |
GeneTreei | ENSGT00940000153768 |
HOGENOMi | CLU_000590_0_1_1 |
InParanoidi | O75179 |
OMAi | FGANIDH |
OrthoDBi | 1115202at2759 |
PhylomeDBi | O75179 |
TreeFami | TF328552 |
Enzyme and pathway databases
PathwayCommonsi | O75179 |
Miscellaneous databases
BioGRID-ORCSi | 26057, 89 hits in 850 CRISPR screens |
ChiTaRSi | ANKRD17, human |
GeneWikii | ANKRD17 |
GenomeRNAii | 26057 |
Pharosi | O75179, Tbio |
PROi | PR:O75179 |
RNActi | O75179, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000132466, Expressed in sural nerve and 247 other tissues |
ExpressionAtlasi | O75179, baseline and differential |
Genevisiblei | O75179, HS |
Family and domain databases
Gene3Di | 1.25.40.20, 8 hits 3.30.1370.10, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf |
Pfami | View protein in Pfam PF00023, Ank, 2 hits PF12796, Ank_2, 9 hits PF00013, KH_1, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 25 hits SM00322, KH, 1 hit |
SUPFAMi | SSF48403, SSF48403, 3 hits SSF54791, SSF54791, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 20 hits PS50084, KH_TYPE_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ANR17_HUMAN | |
Accessioni | O75179Primary (citable) accession number: O75179 Secondary accession number(s): E7EUV3 Q9H6J9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 23, 2007 |
Last sequence update: | October 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 170 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM - Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations