Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 147 (08 May 2019)
Sequence version 2 (11 Jan 2011)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Zinc finger BED domain-containing protein 4

Gene

ZBED4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri115 – 172BED-type 1PROSITE-ProRule annotationAdd BLAST58
Zinc fingeri285 – 342BED-type 2PROSITE-ProRule annotationAdd BLAST58
Zinc fingeri456 – 512BED-type 3PROSITE-ProRule annotationAdd BLAST57
Zinc fingeri558 – 615BED-type 4PROSITE-ProRule annotationAdd BLAST58

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger BED domain-containing protein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBED4
Synonyms:KIAA0637
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:20721 ZBED4

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612552 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O75132

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
9889

Open Targets

More...
OpenTargetsi
ENSG00000100426

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134948378

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZBED4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000665631 – 1171Zinc finger BED domain-containing protein 4Add BLAST1171

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki43Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki489Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei624PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O75132

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O75132

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O75132

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O75132

PeptideAtlas

More...
PeptideAtlasi
O75132

PRoteomics IDEntifications database

More...
PRIDEi
O75132

ProteomicsDB human proteome resource

More...
ProteomicsDBi
49794

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O75132

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O75132

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in testis, kidney and spinal cord and brain corpus callosum. Expressed in the retina, found in the cone photoreceptors, Mueller cells, cone pedicles and in the innermost retinal layer.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000100426 Expressed in 164 organ(s), highest expression level in leukocyte

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O75132 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA045341

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
MEOX2P502223EBI-2860059,EBI-748397

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115219, 6 interactors

Protein interaction database and analysis system

More...
IntActi
O75132, 13 interactors

Molecular INTeraction database

More...
MINTi
O75132

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000216268

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O75132

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi25 – 30Asp/Glu-rich (acidic)6
Compositional biasi533 – 536Poly-Ser4

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri115 – 172BED-type 1PROSITE-ProRule annotationAdd BLAST58
Zinc fingeri285 – 342BED-type 2PROSITE-ProRule annotationAdd BLAST58
Zinc fingeri456 – 512BED-type 3PROSITE-ProRule annotationAdd BLAST57
Zinc fingeri558 – 615BED-type 4PROSITE-ProRule annotationAdd BLAST58

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IR9V Eukaryota
ENOG4111I2V LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161365

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000139424

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O75132

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSPAWKH

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O75132

TreeFam database of animal gene trees

More...
TreeFami
TF322818

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037220 BED_dom
IPR008906 HATC_C_dom
IPR012337 RNaseH-like_sf
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05699 Dimer_Tnp_hAT, 1 hit
PF02892 zf-BED, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00614 ZnF_BED, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF140996 SSF140996, 1 hit
SSF53098 SSF53098, 1 hit
SSF57667 SSF57667, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50808 ZF_BED, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O75132-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENNLKTCPK EDGDFVSDKI KFKIEEEDDD GIPPDSLERM DFKSEQEDMK
60 70 80 90 100
QTDSGGERAG LGGTGCSCKP PGKYLSAESE DDYGALFSQY SSTLYDVAME
110 120 130 140 150
AVTQSLLSSR NMSSRKKSPA WKHFFISPRD STKAICMYCV KEFSRGKNEK
160 170 180 190 200
DLSTSCLMRH VRRAHPTVLI QENGSVSAVS SFPSPSLLLP PQPADAGDLS
210 220 230 240 250
TILSPIKLVQ KVASKIPSPD RITEESVSVV SSEEISSDMS VSEKCGREEA
260 270 280 290 300
LVGSSPHLPA LHYDEPAENL AEKSLPLPKS TSGSRRRSAV WKHFYLSPLD
310 320 330 340 350
NSKAVCIHCM NEFSRGKNGK DLGTSCLIRH MWRAHRAIVL QENGGTGIPP
360 370 380 390 400
LYSTPPTLLP SLLPPEGELS SVSSSPVKPV RESPSASSSP DRLTEDLQSH
410 420 430 440 450
LNPGDGLMED VAAFSSSDDI GEASASSPEK QQADGLSPRL FESGAIFQQN
460 470 480 490 500
KKVMKRLKSE VWHHFSLAPM DSLKAECRYC GCAISRGKKG DVGTSCLMRH
510 520 530 540 550
LYRRHPEVVG SQKGFLGASL ANSPYATLAS AESSSSKLTD LPTVVTKNNQ
560 570 580 590 600
VMFPVNSKKT SKLWNHFSIC SADSTKVVCL HCGRTISRGK KPTNLGTSCL
610 620 630 640 650
LRHLQRFHSN VLKTEVSETA RPSSPDTRVP RGTELSGASS FDDTNEKFYD
660 670 680 690 700
SHPVAKKITS LIAEMIALDL QPYSFVDNVG FNRLLEYLKP QYSLPAPSYF
710 720 730 740 750
SRTAIPGMYD NVKQIIMSHL KEAESGVIHF TSGIWMSNQT REYLTLTAHW
760 770 780 790 800
VSFESPARPR CDDHHCSALL DVSQVDCDYS GNSIQKQLEC WWEAWVTSTG
810 820 830 840 850
LQVGITVTDN ASIGKTLNEG EHSSVQCFSH TVNLIVSEAI KSQRMVQNLL
860 870 880 890 900
SLARKICERV HRSPKAKEKL AELQREYALP QHHLIQDVPS KWSTSFHMLE
910 920 930 940 950
RLIEQKRAIN EMSVECNFRE LISCDQWEVM QSVCRALKPF EAASREMSTQ
960 970 980 990 1000
MSTLSQVIPM VHILNRKVEM LFEETMGIDT MLRSLKEAMV SRLSATLHDP
1010 1020 1030 1040 1050
RYVFATLLDP RYKASLFTEE EAEQYKQDLI RELELMNSTS EDVAASHRCD
1060 1070 1080 1090 1100
AGSPSKDSAA EENLWSLVAK VKKKDPREKL PEAMVLAYLE EEVLEHSCDP
1110 1120 1130 1140 1150
LTYWNLKKAS WPGLSALAVR FLGCPPSIVP SEKLFNTPTE NGSLGQSRLM
1160 1170
MEHFEKLIFL KVNLPLIYFQ Y
Length:1,171
Mass (Da):130,322
Last modified:January 11, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i485746484E87B389
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA31612 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti584R → Q in AAI17671 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027809420I → V3 PublicationsCorresponds to variant dbSNP:rs910799Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB014537 mRNA Translation: BAA31612.2 Different initiation.
CR456387 mRNA Translation: CAG30273.1
AL117328 Genomic DNA No translation available.
BC117670 mRNA Translation: AAI17671.1
BC167155 mRNA Translation: AAI67155.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33677.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T00380

NCBI Reference Sequences

More...
RefSeqi
NP_055653.2, NM_014838.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000216268; ENSP00000216268; ENSG00000100426

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9889

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9889

UCSC genome browser

More...
UCSCi
uc003bix.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014537 mRNA Translation: BAA31612.2 Different initiation.
CR456387 mRNA Translation: CAG30273.1
AL117328 Genomic DNA No translation available.
BC117670 mRNA Translation: AAI17671.1
BC167155 mRNA Translation: AAI67155.1
CCDSiCCDS33677.1
PIRiT00380
RefSeqiNP_055653.2, NM_014838.2

3D structure databases

SMRiO75132
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115219, 6 interactors
IntActiO75132, 13 interactors
MINTiO75132
STRINGi9606.ENSP00000216268

PTM databases

iPTMnetiO75132
PhosphoSitePlusiO75132

Polymorphism and mutation databases

BioMutaiZBED4

Proteomic databases

EPDiO75132
jPOSTiO75132
MaxQBiO75132
PaxDbiO75132
PeptideAtlasiO75132
PRIDEiO75132
ProteomicsDBi49794

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
9889
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000216268; ENSP00000216268; ENSG00000100426
GeneIDi9889
KEGGihsa:9889
UCSCiuc003bix.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9889
DisGeNETi9889

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZBED4

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0016602
HGNCiHGNC:20721 ZBED4
HPAiHPA045341
MIMi612552 gene
neXtProtiNX_O75132
OpenTargetsiENSG00000100426
PharmGKBiPA134948378

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IR9V Eukaryota
ENOG4111I2V LUCA
GeneTreeiENSGT00940000161365
HOGENOMiHOG000139424
InParanoidiO75132
OMAiKSPAWKH
PhylomeDBiO75132
TreeFamiTF322818

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZBED4 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9889

Protein Ontology

More...
PROi
PR:O75132

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000100426 Expressed in 164 organ(s), highest expression level in leukocyte
GenevisibleiO75132 HS

Family and domain databases

InterProiView protein in InterPro
IPR037220 BED_dom
IPR008906 HATC_C_dom
IPR012337 RNaseH-like_sf
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf
PfamiView protein in Pfam
PF05699 Dimer_Tnp_hAT, 1 hit
PF02892 zf-BED, 4 hits
SMARTiView protein in SMART
SM00614 ZnF_BED, 4 hits
SUPFAMiSSF140996 SSF140996, 1 hit
SSF53098 SSF53098, 1 hit
SSF57667 SSF57667, 4 hits
PROSITEiView protein in PROSITE
PS50808 ZF_BED, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZBED4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75132
Secondary accession number(s): B2RZH1, Q1ECU0, Q9UGG8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: January 11, 2011
Last modified: May 8, 2019
This is version 147 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again