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Entry version 156 (13 Feb 2019)
Sequence version 2 (30 Nov 2010)
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Protein

Zinc finger protein 623

Gene

ZNF623

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri123 – 145C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri151 – 173C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri179 – 201C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri207 – 229C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri235 – 257C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri263 – 285C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri291 – 313C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri319 – 341C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri347 – 369C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri375 – 397C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri403 – 425C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 623
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF623
Synonyms:KIAA0628
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000183309.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29084 ZNF623

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O75123

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134969295

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF623

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476941 – 536Zinc finger protein 623Add BLAST536

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki445Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O75123

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O75123

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O75123

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O75123

PeptideAtlas

More...
PeptideAtlasi
O75123

PRoteomics IDEntifications database

More...
PRIDEi
O75123

ProteomicsDB human proteome resource

More...
ProteomicsDBi
49779

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O75123

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O75123

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000183309 Expressed in 209 organ(s), highest expression level in cerebellar vermis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O75123 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O75123 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA044372

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115169, 4 interactors

Protein interaction database and analysis system

More...
IntActi
O75123, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000434258

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O75123

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O75123

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri123 – 145C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri151 – 173C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri179 – 201C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri207 – 229C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri235 – 257C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri263 – 285C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri291 – 313C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri319 – 341C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri347 – 369C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri375 – 397C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri403 – 425C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri431 – 453C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri459 – 481C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018163

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O75123

KEGG Orthology (KO)

More...
KOi
K09228

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O75123

TreeFam database of animal gene trees

More...
TreeFami
TF337005

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 13 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 13 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O75123-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MILLSFVSDS NVGTGEKKVT EAWISEDENS HRTTSDRLTV MELPSPESEE
60 70 80 90 100
VHEPRLGELL GNPEGQSLGS SPSQDRGCKQ VTVTHWKIQT GETAQVCTKS
110 120 130 140 150
GRNHILNSDL LLLQRELIEG EANPCNICGK TFTFNSDLVR HRISHAGEKP
160 170 180 190 200
YTCDQCGKGF GQSSHLMEHQ RIHTGERLYV CNVCGKDFIH YSGLIEHQRV
210 220 230 240 250
HSGEKPFKCA QCGKAFCHSS DLIRHQRVHT RERPFECKEC GKGFSQSSLL
260 270 280 290 300
IRHQRIHTGE RPYECNECGK SFIRSSSLIR HYQIHTEVKQ YECKECGKAF
310 320 330 340 350
RHRSDLIEHQ RIHTGERPFE CNECGKAFIR SSKLIQHQRI HTGERPYVCN
360 370 380 390 400
ECGKRFSQTS NFTQHQRIHT GEKLYECNEC GKAFFLSSYL IRHQKIHTGE
410 420 430 440 450
RVYECKECGK AFLQKAHLTE HQKIHSGDRP FECKDCGKAF IQSSKLLLHQ
460 470 480 490 500
IIHTGEKPYV CSYCGKGFIQ RSNFLQHQKI HTEEKLYECS QYGRDFNSTT
510 520 530
NVKNNQRVHQ EGLSLSKAPI HLGERSVDKG EHTGNL
Length:536
Mass (Da):61,392
Last modified:November 30, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i798EB7EC0F0A4366
GO
Isoform 2 (identifier: O75123-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-40: Missing.

Note: No experimental confirmation available.
Show »
Length:496
Mass (Da):56,956
Checksum:i4D439CB2E91BA7DD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MT18A0A0A0MT18_HUMAN
Zinc finger protein 623
ZNF623
496Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YW98A0A0J9YW98_HUMAN
HCG31704
ZNF623 hCG_31704
536Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA31603 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAG57854 differs from that shown. Reason: Frameshift at position 467.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052881126N → D2 PublicationsCorresponds to variant dbSNP:rs4874084Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0535011 – 40Missing in isoform 2. 1 PublicationAdd BLAST40

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB014528 mRNA Translation: BAA31603.2 Different initiation.
AK294695 mRNA Translation: BAG57854.1 Frameshift.
AC067930 Genomic DNA No translation available.
AC105210 Genomic DNA No translation available.
BC067516 mRNA Translation: AAH67516.1
BC067517 mRNA Translation: AAH67517.1
BC067518 mRNA Translation: AAH67518.1
BC075056 mRNA Translation: AAH75056.1
BC075057 mRNA Translation: AAH75057.1
BC112899 mRNA Translation: AAI12900.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34957.1 [O75123-1]
CCDS47931.1 [O75123-2]

NCBI Reference Sequences

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RefSeqi
NP_001075949.1, NM_001082480.2
NP_001248772.1, NM_001261843.1
NP_055604.3, NM_014789.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.43133
Hs.694018
Hs.745418

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000501748; ENSP00000445979; ENSG00000183309

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9831

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9831

UCSC genome browser

More...
UCSCi
uc003yzd.3 human [O75123-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB014528 mRNA Translation: BAA31603.2 Different initiation.
AK294695 mRNA Translation: BAG57854.1 Frameshift.
AC067930 Genomic DNA No translation available.
AC105210 Genomic DNA No translation available.
BC067516 mRNA Translation: AAH67516.1
BC067517 mRNA Translation: AAH67517.1
BC067518 mRNA Translation: AAH67518.1
BC075056 mRNA Translation: AAH75056.1
BC075057 mRNA Translation: AAH75057.1
BC112899 mRNA Translation: AAI12900.1
CCDSiCCDS34957.1 [O75123-1]
CCDS47931.1 [O75123-2]
RefSeqiNP_001075949.1, NM_001082480.2
NP_001248772.1, NM_001261843.1
NP_055604.3, NM_014789.3
UniGeneiHs.43133
Hs.694018
Hs.745418

3D structure databases

ProteinModelPortaliO75123
SMRiO75123
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115169, 4 interactors
IntActiO75123, 1 interactor
STRINGi9606.ENSP00000434258

PTM databases

iPTMnetiO75123
PhosphoSitePlusiO75123

Polymorphism and mutation databases

BioMutaiZNF623

Proteomic databases

EPDiO75123
jPOSTiO75123
MaxQBiO75123
PaxDbiO75123
PeptideAtlasiO75123
PRIDEiO75123
ProteomicsDBi49779

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
9831
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000501748; ENSP00000445979; ENSG00000183309
GeneIDi9831
KEGGihsa:9831
UCSCiuc003yzd.3 human [O75123-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9831
EuPathDBiHostDB:ENSG00000183309.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF623
HGNCiHGNC:29084 ZNF623
HPAiHPA044372
neXtProtiNX_O75123
PharmGKBiPA134969295

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiO75123
KOiK09228
OrthoDBi1318335at2759
PhylomeDBiO75123
TreeFamiTF337005

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF623 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9831

Protein Ontology

More...
PROi
PR:O75123

Gene expression databases

BgeeiENSG00000183309 Expressed in 209 organ(s), highest expression level in cerebellar vermis
ExpressionAtlasiO75123 baseline and differential
GenevisibleiO75123 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 13 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 13 hits
SUPFAMiSSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 13 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN623_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75123
Secondary accession number(s): A4FU80, B4DGP3, E7ENV5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: November 30, 2010
Last modified: February 13, 2019
This is version 156 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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