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Entry version 110 (29 Sep 2021)
Sequence version 2 (11 Jul 2012)
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Protein

Exocyst complex component sec15

Gene

sec15

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processExocytosis, Protein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SPO-264876, Insulin processing

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Exocyst complex component sec15
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:sec15
ORF Names:SPCC1183.01, SPCC1672.13
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPCC1183.01, sec15

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPCC1183.01

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001189581 – 768Exocyst complex component sec15Add BLAST768

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O75006

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O75006

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O75006

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

The exocyst complex is composed of sec3, sec5, sec6, sec8, sec10, sec15, exo70 and exo84.

Interacts with sec4.

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4896.SPCC1183.01.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O75006

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili69 – 115Sequence analysisAdd BLAST47

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SEC15 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG2176, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_009437_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O75006

Identification of Orthologs from Complete Genome Data

More...
OMAi
RDHYNEV

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.357.30, 1 hit
1.20.58.670, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007225, EXOC6/Sec15
IPR042045, EXOC6/Sec15_C_dom1
IPR042044, EXOC6PINT-1/Sec15/Tip20_C_dom2

The PANTHER Classification System

More...
PANTHERi
PTHR12702, PTHR12702, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04091, Sec15, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF025007, Sec15, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O75006-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIDVLEFVD KIASIESAGD TLDRLPQLIS LACEKGQETQ VYERLNELAS
60 70 80 90 100
KSAIRVEQLS AENNQDFSKS VNQLSVVRSE LRSLQSLMAD LNTDIQASGR
110 120 130 140 150
DLQNMKQQLN SLSTSERFLT KYHNLVRSCM QVLHQVQYSQ ELLSKKQYLP
160 170 180 190 200
TLRICSEISE VHLKRLDGLG MYSTIQQYIV TTKEAICSAV MEDLHEWLFS
210 220 230 240 250
IRQKLPLVGK SCSQQIDEAR RRWAREYKED LVNLSSKTSI SLELYLLEMM
260 270 280 290 300
DFSPLDNEIV KISFEPLYIC LQVHSYLGLL SSFRSSFERD RRRQQEFLAP
310 320 330 340 350
KSLTTLDMAV VSEWLNSIAG FMIVEYYILQ CIPNFRSYEE VQNIWTIICE
360 370 380 390 400
KLVETILSVA FTEQSTTTII KLKNQIVLLM HTMERFGFSV ESLRNLCVEL
410 420 430 440 450
IDAFGGALIL KHSVFFEEAF EKDVYAPMIV ETQEEYDHYI APYWNFPSEP
460 470 480 490 500
FPRTMSFSKM CPLCCTTLSK FVRHFFMFLN DSVILATEVN EKAPRFYRRF
510 520 530 540 550
ILRSLVDRLK SLYPKLALSQ MSQLVKNFYA FEDPLLQIEK SLVLNKPIHQ
560 570 580 590 600
IGAEASSSNN VKSTELLEGL ANARKSALHE IFVKINLKID DFLGLAEYDW
610 620 630 640 650
TTTQVRKDVS GYLQEMVTYL QTMYLESLAG LPKHDKSYVY LETLDHLCTA
660 670 680 690 700
MVDLLSDPSI RKVTTAAAEG FKLDVEYLES FAAQVPDQSI VNADSFIELR
710 720 730 740 750
QCANLLLGDN MEEYLDTDKF MRDFNRLQPA VAIKFLERHI NNYSANPLSN
760
DRPKRRAIEI LIATLKKR
Length:768
Mass (Da):88,550
Last modified:July 11, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7639A682EDEB0839
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20451.2

Protein sequence database of the Protein Information Resource

More...
PIRi
T40841

NCBI Reference Sequences

More...
RefSeqi
NP_587884.2, NM_001022876.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPCC1183.01.1; SPCC1183.01.1:pep; SPCC1183.01

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2538937

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPCC1183.01

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20451.2
PIRiT40841
RefSeqiNP_587884.2, NM_001022876.2

3D structure databases

SMRiO75006
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4896.SPCC1183.01.1

PTM databases

SwissPalmiO75006

Proteomic databases

MaxQBiO75006
PaxDbiO75006

Genome annotation databases

EnsemblFungiiSPCC1183.01.1; SPCC1183.01.1:pep; SPCC1183.01
GeneIDi2538937
KEGGispo:SPCC1183.01

Organism-specific databases

PomBaseiSPCC1183.01, sec15
VEuPathDBiFungiDB:SPCC1183.01

Phylogenomic databases

eggNOGiKOG2176, Eukaryota
HOGENOMiCLU_009437_2_0_1
InParanoidiO75006
OMAiRDHYNEV

Enzyme and pathway databases

ReactomeiR-SPO-264876, Insulin processing

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O75006

Family and domain databases

Gene3Di1.10.357.30, 1 hit
1.20.58.670, 1 hit
InterProiView protein in InterPro
IPR007225, EXOC6/Sec15
IPR042045, EXOC6/Sec15_C_dom1
IPR042044, EXOC6PINT-1/Sec15/Tip20_C_dom2
PANTHERiPTHR12702, PTHR12702, 1 hit
PfamiView protein in Pfam
PF04091, Sec15, 1 hit
PIRSFiPIRSF025007, Sec15, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSEC15_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O75006
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: July 11, 2012
Last modified: September 29, 2021
This is version 110 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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