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Entry version 125 (25 May 2022)
Sequence version 2 (11 Jul 2012)
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Protein

Uncharacterized transcriptional regulatory protein C757.04

Gene

SPCC757.04

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi10 – 36Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST27

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized transcriptional regulatory protein C757.04
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPCC757.04
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPCC757.04

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPCC757.04

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003103871 – 636Uncharacterized transcriptional regulatory protein C757.04Add BLAST636

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O74915

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O74915

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
275669, 10 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPCC757.04.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...
AlphaFoldDBi
O74915

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni556 – 581DisorderedSequence analysisAdd BLAST26

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QTSE, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_015811_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O74915

Identification of Orthologs from Complete Genome Data

More...
OMAi
YNFDFTL

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00067, GAL4, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007219, Transcription_factor_dom_fun
IPR001138, Zn2-C6_fun-type_DNA-bd
IPR036864, Zn2-C6_fun-type_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04082, Fungal_trans, 1 hit
PF00172, Zn_clus, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00906, Fungal_trans, 1 hit
SM00066, GAL4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57701, SSF57701, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00463, ZN2_CY6_FUNGAL_1, 1 hit
PS50048, ZN2_CY6_FUNGAL_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O74915-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHRIRHLSC LACRRKKVKC NRQYPCTRCL KYGEACTYDE RDNRKKRHSL
60 70 80 90 100
SYLHSLESQL ARLESFIMTL KNSDPEGRDE MLKSVVFSDH LTEPNDQEVK
110 120 130 140 150
SEGPIEYPVF LNVQDSKTVS FYGPTSAYDL SLPDITKDNK TTWNFQASYS
160 170 180 190 200
PMVSECLKLF FRYQYSQFLF VYRESFLSDY YYNFHDGFYC TEHLIYAICA
210 220 230 240 250
IGASMSDDEN ISRHSKSYYD ASWQKLLEFG LDRSHLTSVQ CLLCLGYYDI
260 270 280 290 300
GMGNTSLGWL LSGLAFRMGQ DLGFQLNPEN WYIDNSPAIS SADSDIRRRV
310 320 330 340 350
FWGSYVADKF IGFIMGRPTM LKRSDASIPG SNQLPEFAGL EEFKLNVTDY
360 370 380 390 400
MSLTDFSVCD AVALFVDLSD IADSILLNMF SPTSKNRATN INCVLSNLGK
410 420 430 440 450
YNLELMNWHY KLPDTISWRT IDLKKDRIPN LCAVSLYYHL IRICLNRPFL
460 470 480 490 500
SRKEVTANDL TPKTICTDSI NEIVTVIRAH RTANGLRYST LYIVYAAIVS
510 520 530 540 550
CSVILLLRDM CTDSELLTLN NDMMFFIEVL KECSQTWKLA QRSIVLIENT
560 570 580 590 600
LKGKTNSQST SEFVSPISDT ENGSSSQQVS EAKDIVEPSD VLDELQKFDL
610 620 630
LPENDDNFQT FQAFYGGPPI ILSPNLYEKK LNEKTL
Length:636
Mass (Da):72,887
Last modified:July 11, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1B37CF9287CF640F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA21229.2

Protein sequence database of the Protein Information Resource

More...
PIRi
T41595

NCBI Reference Sequences

More...
RefSeqi
NP_587679.2, NM_001022674.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPCC757.04.1; SPCC757.04.1:pep; SPCC757.04

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2539097

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPCC757.04

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA21229.2
PIRiT41595
RefSeqiNP_587679.2, NM_001022674.2

3D structure databases

AlphaFoldDBiO74915
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi275669, 10 interactors
STRINGi4896.SPCC757.04.1

Proteomic databases

MaxQBiO74915
PaxDbiO74915

Genome annotation databases

EnsemblFungiiSPCC757.04.1; SPCC757.04.1:pep; SPCC757.04
GeneIDi2539097
KEGGispo:SPCC757.04

Organism-specific databases

PomBaseiSPCC757.04
VEuPathDBiFungiDB:SPCC757.04

Phylogenomic databases

eggNOGiENOG502QTSE, Eukaryota
HOGENOMiCLU_015811_1_0_1
InParanoidiO74915
OMAiYNFDFTL

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O74915

Family and domain databases

CDDicd00067, GAL4, 1 hit
Gene3Di4.10.240.10, 1 hit
InterProiView protein in InterPro
IPR007219, Transcription_factor_dom_fun
IPR001138, Zn2-C6_fun-type_DNA-bd
IPR036864, Zn2-C6_fun-type_DNA-bd_sf
PfamiView protein in Pfam
PF04082, Fungal_trans, 1 hit
PF00172, Zn_clus, 1 hit
SMARTiView protein in SMART
SM00906, Fungal_trans, 1 hit
SM00066, GAL4, 1 hit
SUPFAMiSSF57701, SSF57701, 1 hit
PROSITEiView protein in PROSITE
PS00463, ZN2_CY6_FUNGAL_1, 1 hit
PS50048, ZN2_CY6_FUNGAL_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYJ74_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O74915
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: July 11, 2012
Last modified: May 25, 2022
This is version 125 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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